P07098

Gastric triacylglycerol lipase    //   UniProt Profile 

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Species

 H. sapiens

Number of Interactions

 13 / 16

Average Interaction Score

 0.885

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.8 Experimental: experimental eSLDB PubMed 
N/A Cellular component (GO:0005575) 0.3 Unknown: no biological data available GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Lysosome (GO:0005764) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular region (GO:0005576) 0.79 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.79 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

P07098

Interaction Score
0.997

P49810

(UniProtKB/Swiss-Prot/P) Details

Presenilin-2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Cell surface (GO:0009986) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Endomembrane system (GO:0012505) 1 Experimental: experimental Organelle PubMed 
Cytosol Neuronal cell body (GO:0043025) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cell cortex (GO:0005938) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Mitochondrion Mitochondrial inner membrane (GO:0005743) 0.7 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nuclear inner membrane (GO:0005637) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Integral to nuclear inner membrane (GO:0005639) 1 Experimental: experimental Organelle PubMed 
Nucleus Macromolecular complex (GO:0032991) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 1 Experimental: experimental eSLDB PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 1 Experimental: experimental Organelle PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 1 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 1 Experimental: experimental eSLDB PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Golgi membrane (GO:0000139) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Lysosomal membrane (GO:0005765) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Z disc (GO:0030018) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Centrosome (GO:0005813) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Chromosome (GO:0005694) 1 Experimental: experimental Organelle PubMed 
Nucleus Kinetochore (GO:0000776) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Growth cone (GO:0030426) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Dendritic shaft (GO:0043198) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Axon (GO:0030424) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Ciliary rootlet (GO:0035253) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 1 Unknown: HDA GO PubMed 
Membrane Integral to membrane (GO:0016021) 1 Experimental: experimental eSLDB PubMed 
Membrane Membrane raft (GO:0045121) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Integral to plasma membrane (GO:0005887) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Organelle inner membrane (GO:0019866) 1 Experimental: experimental Organelle PubMed 
Membrane Neuromuscular junction (GO:0031594) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

P07098

Interaction Score
0.987

P20062

(UniProtKB/Swiss-Prot/P) Details

Transcobalamin-2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.79 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.86 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endosome (GO:0005768) 0.79 Unknown: traceable author statement GO PubMed 
Cytosol Lysosomal lumen (GO:0043202) 0.86 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.958 Experimental: inferred from direct assay GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P07098

Interaction Score
0.977

O95297

(UniProtKB/Swiss-Prot/P) Details

Myelin protein zero-like protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Cell surface (GO:0009986) 0.997 Unknown: HDA GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to membrane (GO:0016021) 0.997 Experimental: experimental eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.997 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 0.997 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.997 Unknown: inferred from electronic annotation GO PubMed 
Membrane Focal adhesion (GO:0005925) 0.997 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P07098

Interaction Score
0.976

Q6UWE0

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase LRSAM1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.982 Experimental: inferred from direct assay GO PubMed 
Membrane Ion channel complex (GO:0034702) 0.982 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.982 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P07098

Interaction Score
0.966

P04118

(UniProtKB/Swiss-Prot/P) Details

Colipase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.8 Experimental: experimental eSLDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.937 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.937 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular region (GO:0005576) 0.937 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed 

P07098

Interaction Score
0.951

P15056

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein kinase B-raf

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Intracellular (GO:0005622) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.79 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.79 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.7 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P07098

Interaction Score
0.939

Q15818

(UniProtKB/Swiss-Prot/P) Details

Neuronal pentraxin-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.86 Experimental: experimental eSLDB PubMed 
Secretory-pathway Transport vesicle (GO:0030133) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Vesicle (GO:0031982) 0.8 Experimental: experimental eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P07098

Interaction Score
0.935

P20648

(UniProtKB/Swiss-Prot/P) Details

Potassium-transporting ATPase alpha chain 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.86 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular space (GO:0005615) 0.86 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 0.998 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.998 Predicted: SVM decision tree eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.998 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.998 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 0.998 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.998 Unknown: traceable author statement GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P07098

Interaction Score
0.917

Q96EP0

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase RNF31

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol LUBAC complex (GO:0071797) 0.992 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.992 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.992 Unknown: traceable author statement GO PubMed 
Cytosol Cytosol (GO:0005829) 0.992 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.91 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.91 Predicted: pTarget method LOCATE PubMed 
Membrane Internal side of plasma membrane (GO:0009898) 0.91 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane CD40 receptor complex (GO:0035631) 0.91 Predicted: inferred from sequence or structural similarity GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P07098

Interaction Score
0.858

Q9H0F6

(UniProtKB/Swiss-Prot/P) Details

Sharpin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol LUBAC complex (GO:0071797) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Lysosome (GO:0005764) 1 Predicted: pTarget method LOCATE PubMed 
Membrane Dendrite (GO:0030425) 0.657 Unknown: inferred from electronic annotation GO PubMed 
Membrane Postsynaptic density (GO:0014069) 0.657 Unknown: inferred from electronic annotation GO PubMed 
Membrane Cell junction (GO:0030054) 0.657 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P07098

Interaction Score
0.838

Q658V6

(UniProtKB/TrEmbl/P) Details

Sodium/potassium-transporting ATPase subunit alpha

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P07098

Interaction Score
0.672

A0A2R8Y8E0

(UniProtKB/TrEmbl/P) Details

Serine/threonine-protein kinase B-raf

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P07098

Interaction Score
0.49

Q6PJD5

(UniProtKB/TrEmbl/P) Details

SHARPIN protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

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ComPPI is published in Nucleic Acids Research Database Issue 2015