P08185

Corticosteroid-binding globulin    //   UniProt Profile 

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Species

 H. sapiens

Number of Interactions

 11 / 18

Average Interaction Score

 0.918

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.8 Experimental: experimental eSLDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.79 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.79 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.3 Unknown: HDA GO PubMed 

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

P08185

Interaction Score
0.992

P19021

(UniProtKB/Swiss-Prot/P) Details

Peptidyl-glycine alpha-amidating monooxygenase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.971 Predicted: SVM decision tree eSLDB PubMed 
Membrane Cell surface (GO:0009986) 0.998 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Perikaryon (GO:0043204) 0.986 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytosol (GO:0005829) 0.986 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 0.986 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.971 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Trans-Golgi network (GO:0005802) 0.971 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Secretory granule membrane (GO:0030667) 0.971 Unknown: inferred from electronic annotation GO PubMed 
Membrane Neuron projection (GO:0043005) 0.998 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.998 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 0.998 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.998 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.998 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.998 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.998 Experimental: experimental Organelle PubMed 
Cytosol Vesicle (GO:0031982) 0.986 Experimental: experimental eSLDB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.986 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P08185

Interaction Score
0.99

P04440

(UniProtKB/Swiss-Prot/P) Details

HLA class II histocompatibility antigen, DP beta 1 chain

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Cell surface (GO:0009986) 0.999 Experimental: inferred from mutant phenotype GO PubMed 
Nucleus Nucleus (GO:0005634) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Integral to lumenal side of endoplasmic reticulum membrane (GO:0071556) 0.942 Unknown: traceable author statement GO PubMed 
Secretory-pathway Golgi membrane (GO:0000139) 0.942 Unknown: traceable author statement GO PubMed 
Secretory-pathway Trans-Golgi network membrane (GO:0032588) 0.942 Unknown: traceable author statement GO PubMed 
Secretory-pathway Endosome membrane (GO:0010008) 0.942 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Lysosome (GO:0005764) 0.79 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Lysosomal membrane (GO:0005765) 0.79 Unknown: traceable author statement GO PubMed 
Secretory-pathway Endocytic vesicle membrane (GO:0030666) 0.942 Unknown: traceable author statement GO PubMed 
Secretory-pathway ER to Golgi transport vesicle membrane (GO:0012507) 0.942 Unknown: traceable author statement GO PubMed 
Secretory-pathway Clathrin-coated endocytic vesicle membrane (GO:0030669) 0.942 Unknown: traceable author statement GO PubMed 
Secretory-pathway Transport vesicle membrane (GO:0030658) 0.942 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Membrane (GO:0016020) 0.999 Unknown: HDA GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.999 Experimental: experimental eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.999 Unknown: traceable author statement GO PubMed 
Membrane MHC class II protein complex (GO:0042613) 0.999 Experimental: inferred from direct assay GO PubMed 
Membrane Cell junction (GO:0030054) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P08185

Interaction Score
0.989

P02751

(UniProtKB/Swiss-Prot/P) Details

Fibronectin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.971 Predicted: SVM decision tree eSLDB PubMed 
Secretory-pathway Endoplasmic reticulum lumen (GO:0005788) 0.971 Unknown: traceable author statement GO PubMed 
Secretory-pathway Endoplasmic reticulum-Golgi intermediate compartment (GO:0005793) 0.971 Experimental: inferred from direct assay GO PubMed 
Cytosol Lysosome (GO:0005764) 0.79 Predicted: pTarget method LOCATE PubMed 
Secretory-pathway Platelet alpha granule lumen (GO:0031093) 0.971 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 1 Unknown: non-traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 1 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular region (GO:0005576) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 1 Experimental: inferred from direct assay GO PubMed 
Extracellular Fibrinogen complex (GO:0005577) 1 Experimental: inferred from direct assay GO PubMed 
Extracellular Blood microparticle (GO:0072562) 1 Unknown: HDA GO PubMed 
Extracellular Extracellular matrix (GO:0031012) 1 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular matrix (GO:0031012) 1 Experimental: experimental MatrixDB PubMed 
Extracellular Basement membrane (GO:0005604) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Membrane (GO:0016020) 0.86 Experimental: experimental MatrixDB PubMed 
Membrane Apical plasma membrane (GO:0016324) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.79 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P08185

Interaction Score
0.979

O43405

(UniProtKB/Swiss-Prot/P) Details

Cochlin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.8 Experimental: experimental eSLDB PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.998 Experimental: experimental eSLDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.998 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular matrix (GO:0031012) 0.998 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular matrix (GO:0031012) 0.998 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P08185

Interaction Score
0.979

P36955

(UniProtKB/Swiss-Prot/P) Details

Pigment epithelium-derived factor

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.79 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 0.51 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Melanosome (GO:0042470) 0.79 Unknown: inferred from electronic annotation GO PubMed 
Membrane Axon hillock (GO:0043203) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.994 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.994 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.994 Unknown: HDA GO PubMed 
Extracellular Extracellular matrix (GO:0031012) 0.994 Experimental: experimental MatrixDB PubMed 
Extracellular Basement membrane (GO:0005604) 0.994 Unknown: inferred from electronic annotation GO PubMed 
Membrane Membrane (GO:0016020) 0.86 Experimental: experimental MatrixDB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.51 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P08185

Interaction Score
0.954

P08572

(UniProtKB/Swiss-Prot/P) Details

Collagen alpha-2(IV) chain

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.86 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Secretory-pathway Endoplasmic reticulum lumen (GO:0005788) 0.3 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.979 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.979 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular matrix (GO:0031012) 0.979 Unknown: HDA GO PubMed 
Extracellular Extracellular matrix (GO:0031012) 0.979 Experimental: experimental MatrixDB PubMed 
Extracellular Collagen type IV (GO:0005587) 0.979 Unknown: traceable author statement GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.86 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P08185

Interaction Score
0.897

O00258

(UniProtKB/Swiss-Prot/P) Details

Tail-anchored protein insertion receptor WRB

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.992 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.79 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.79 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P08185

Interaction Score
0.845

Q6MZF4

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein DKFZp686F219

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Lysosome (GO:0005764) 0.7 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular region (GO:0005576) 0.7 Predicted: pTarget method LOCATE PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P08185

Interaction Score
0.845

Q6MZM7

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein DKFZp686O12165

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Lysosome (GO:0005764) 0.7 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular region (GO:0005576) 0.7 Predicted: pTarget method LOCATE PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P08185

Interaction Score
0.838

Q86XF0

(UniProtKB/Swiss-Prot/P) Details

Dihydrofolate reductase 2, mitochondrial

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.998 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.998 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Mitochondrion Mitochondrial matrix (GO:0005759) 0.998 Experimental: inferred from mutant phenotype GO PubMed 
Mitochondrion Mitochondrial inner membrane (GO:0005743) 0.998 Experimental: inferred from mutant phenotype GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P08185

Interaction Score
0.792

Q92791

(UniProtKB/Swiss-Prot/P) Details

Endoplasmic reticulum protein SC65

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.997 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.997 Experimental: experimental Organelle PubMed 
Nucleus Nucleolus (GO:0005730) 0.997 Unknown: traceable author statement GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.8 Experimental: inferred from direct assay GO PubMed 
Nucleus Chromosome (GO:0005694) 0.997 Experimental: experimental Organelle PubMed 
Nucleus Condensed nuclear chromosome (GO:0000794) 0.997 Unknown: traceable author statement GO PubMed 
Nucleus Synaptonemal complex (GO:0000795) 0.997 Unknown: inferred from electronic annotation GO PubMed 
Membrane Catalytic complex (GO:1902494) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Vesicle (GO:0031982) 0.8 Experimental: experimental eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

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ComPPI is published in Nucleic Acids Research Database Issue 2015