P08571

Monocyte differentiation antigen CD14    //   UniProt Profile 

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Species

 H. sapiens

Number of Interactions

 48 / 56

Average Interaction Score

 0.786

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.86 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.902 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endosome membrane (GO:0010008) 0.902 Unknown: traceable author statement GO PubMed 
Secretory-pathway Secretory granule membrane (GO:0030667) 0.902 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.971 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.971 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.971 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.971 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 1 Experimental: experimental eSLDB PubMed 
Membrane Membrane (GO:0016020) 1 Experimental: experimental MatrixDB PubMed 
Membrane Membrane raft (GO:0045121) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Lipopolysaccharide receptor complex (GO:0046696) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Anchored to external side of plasma membrane (GO:0031362) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.86 Unknown: HDA GO PubMed 

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

P08571

Interaction Score
1

O00206

(UniProtKB/Swiss-Prot/P) Details

Toll-like receptor 4

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Cell surface (GO:0009986) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Intracellular (GO:0005622) 0.998 Predicted: inferred from physical interaction GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.998 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.998 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 0.998 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.902 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Early endosome (GO:0005769) 0.902 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Endosome membrane (GO:0010008) 0.902 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Experimental: experimental eSLDB PubMed 
Membrane Lipopolysaccharide receptor complex (GO:0046696) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Lipopolysaccharide receptor complex (GO:0046696) 1 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane External side of plasma membrane (GO:0009897) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Intrinsic to plasma membrane (GO:0031226) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Integral to plasma membrane (GO:0005887) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Receptor complex (GO:0043235) 1 Predicted: inferred from physical interaction GO PubMed 

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed 

P08571

Interaction Score
1

O60603

(UniProtKB/Swiss-Prot/P) Details

Toll-like receptor 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Cell surface (GO:0009986) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cell body (GO:0044297) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.86 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.902 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Phagocytic vesicle membrane (GO:0030670) 0.902 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Secretory granule membrane (GO:0030667) 0.902 Unknown: traceable author statement GO PubMed 
Membrane Cell projection (GO:0042995) 1 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Experimental: experimental eSLDB PubMed 
Membrane Membrane raft (GO:0045121) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: pTarget method LOCATE PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Toll-like receptor 1-Toll-like receptor 2 protein complex (GO:0035354) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Intrinsic to plasma membrane (GO:0031226) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Integral to plasma membrane (GO:0005887) 1 Unknown: traceable author statement GO PubMed 

Interaction Source Database:

IntAct, DIP, BioGRID, HPRD

Interaction Source Publication:

PubMed , PubMed 

P08571

Interaction Score
1

P08174

(UniProtKB/Swiss-Prot/P) Details

Complement decay-accelerating factor

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.928 Predicted: SVM decision tree eSLDB PubMed 
Membrane Flemming body (GO:0090543) 1 Unknown: unspecified method The Human Protein Atlas PubMed 
Membrane Cell surface (GO:0009986) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.51 Unknown: unspecified method The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum-Golgi intermediate compartment membrane (GO:0033116) 0.928 Unknown: traceable author statement GO PubMed 
Secretory-pathway Golgi membrane (GO:0000139) 0.928 Unknown: traceable author statement GO PubMed 
Secretory-pathway Secretory granule membrane (GO:0030667) 0.928 Unknown: traceable author statement GO PubMed 
Secretory-pathway Transport vesicle (GO:0030133) 0.928 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Membrane (GO:0016020) 1 Experimental: experimental MatrixDB PubMed 
Membrane Anchored to membrane (GO:0031225) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Integral to membrane (GO:0016021) 1 Predicted: SVM decision tree eSLDB PubMed 
Membrane Membrane raft (GO:0045121) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.51 Unknown: HDA GO PubMed 

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed 

P08571

Interaction Score
1

O15455

(UniProtKB/Swiss-Prot/P) Details

Toll-like receptor 3

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Cell surface (GO:0009986) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Intracellular (GO:0005622) 0.98 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.98 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 0.76 Unknown: traceable author statement GO PubMed 
Secretory-pathway Golgi membrane (GO:0000139) 0.76 Unknown: traceable author statement GO PubMed 
Secretory-pathway Early endosome (GO:0005769) 0.76 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Endosome membrane (GO:0010008) 0.76 Unknown: traceable author statement GO PubMed 
Cytosol Lysosomal membrane (GO:0005765) 0.98 Unknown: HDA GO PubMed 
Cytosol Endolysosome membrane (GO:0036020) 0.98 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Membrane (GO:0016020) 1 Unknown: non-traceable author statement GO PubMed 
Membrane Integral to membrane (GO:0016021) 1 Experimental: experimental eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: pTarget method LOCATE PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to plasma membrane (GO:0005887) 1 Unknown: traceable author statement GO PubMed 

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed 

P08571

Interaction Score
1

P05107

(UniProtKB/Swiss-Prot/P) Details

Integrin beta-2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Cell surface (GO:0009986) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.79 Predicted: SVM decision tree eSLDB PubMed 
Secretory-pathway Tertiary granule membrane (GO:0070821) 0.3 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Membrane (GO:0016020) 1 Unknown: HDA GO PubMed 
Membrane Integral to membrane (GO:0016021) 1 Predicted: SVM decision tree eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 1 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane External side of plasma membrane (GO:0009897) 1 Unknown: non-traceable author statement GO PubMed 
Membrane Integrin complex (GO:0008305) 1 Unknown: non-traceable author statement GO PubMed 
Membrane Receptor complex (GO:0043235) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.79 Unknown: HDA GO PubMed 

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed 

P08571

Interaction Score
1

O95425

(UniProtKB/Swiss-Prot/P) Details

Supervillin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Midbody (GO:0030496) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Cleavage furrow (GO:0032154) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.996 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.996 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.996 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 0.996 Experimental: experimental Organelle PubMed 
Cytosol Costamere (GO:0043034) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Experimental: experimental Organelle PubMed 
Cytosol Podosome (GO:0002102) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Actin cytoskeleton (GO:0015629) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Actin cytoskeleton (GO:0015629) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Invadopodium (GO:0071437) 1 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Focal adhesion (GO:0005925) 1 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P08571

Interaction Score
1

P20333

(UniProtKB/Swiss-Prot/P) Details

Tumor necrosis factor receptor superfamily member 1B

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.8 Experimental: experimental eSLDB PubMed 
Cytosol Neuronal cell body (GO:0043025) 0.51 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 0.51 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Membrane Varicosity (GO:0043196) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Membrane (GO:0016020) 0.999 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.999 Experimental: experimental eSLDB PubMed 
Membrane Membrane raft (GO:0045121) 0.999 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.999 Unknown: traceable author statement GO PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.999 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed 

P08571

Interaction Score
1

P02788

(UniProtKB/Swiss-Prot/P) Details

Lactotransferrin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.994 Experimental: experimental eSLDB PubMed 
Membrane Cell surface (GO:0009986) 0.96 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.972 Experimental: inferred from mutant phenotype GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.972 Experimental: experimental Human Proteinpedia PubMed 
Nucleus Nucleus (GO:0005634) 0.86 Unknown: HDA GO PubMed 
Nucleus Macromolecular complex (GO:0032991) 0.86 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Phagocytic vesicle lumen (GO:0097013) 0.994 Unknown: traceable author statement GO PubMed 
Secretory-pathway Secretory granule (GO:0030141) 0.994 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Specific granule (GO:0042581) 0.994 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.997 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.997 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular region (GO:0005576) 0.997 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Other organism cell membrane (GO:0044218) 0.997 Experimental: inferred from mutant phenotype GO PubMed 
Extracellular Extracellular space (GO:0005615) 0.997 Experimental: inferred from direct assay GO PubMed 
Membrane Membrane (GO:0016020) 0.96 Experimental: experimental MatrixDB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.972 Unknown: HDA GO PubMed 

Interaction Source Database:

HPRD, BioGRID

Interaction Source Publication:

PubMed 

P08571

Interaction Score
1

P20138

(UniProtKB/Swiss-Prot/P) Details

Myeloid cell surface antigen CD33

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.96 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Tertiary granule membrane (GO:0070821) 0.3 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Predicted: SVM decision tree eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane External side of plasma membrane (GO:0009897) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Integral to plasma membrane (GO:0005887) 1 Unknown: traceable author statement GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P08571

Interaction Score
1

P20073

(UniProtKB/Swiss-Prot/P) Details

Annexin A7

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.971 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.971 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytosol (GO:0005829) 0.971 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear envelope (GO:0005635) 0.992 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.992 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 0.96 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Chromaffin granule membrane (GO:0042584) 0.96 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.971 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 0.971 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.971 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.971 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.971 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P08571

Interaction Score
1

P18428

(UniProtKB/Swiss-Prot/P) Details

Lipopolysaccharide-binding protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Membrane Cell surface (GO:0009986) 0.972 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.997 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.997 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular region (GO:0005576) 0.997 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.997 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.997 Experimental: inferred from direct assay GO PubMed 
Membrane Membrane (GO:0016020) 0.972 Unknown: inferred from electronic annotation GO PubMed 
Membrane Membrane (GO:0016020) 0.972 Experimental: experimental MatrixDB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.3 Unknown: HDA GO PubMed 

Interaction Source Database:

HPRD, DIP, BioGRID

Interaction Source Publication:

PubMed , PubMed 

P08571

Interaction Score
1

Q92572

(UniProtKB/Swiss-Prot/P) Details

AP-3 complex subunit sigma-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.994 Experimental: experimental eSLDB PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.994 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.994 Predicted: pTarget method LOCATE PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.994 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Cytoplasmic vesicle membrane (GO:0030659) 0.994 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Transport vesicle (GO:0030133) 0.994 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane AP-type membrane coat adaptor complex (GO:0030119) 0.86 Unknown: traceable author statement GO PubMed 
Membrane AP-3 adaptor complex (GO:0030123) 0.86 Experimental: inferred from direct assay GO PubMed 
Cytosol Vesicle (GO:0031982) 1 Experimental: experimental eSLDB PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed 

P08571

Interaction Score
0.999

P29033

(UniProtKB/Swiss-Prot/P) Details

Gap junction beta-2 protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Mitochondrion Mitochondrion (GO:0005739) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum-Golgi intermediate compartment (GO:0005793) 0.3 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.996 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.996 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.996 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.996 Predicted: pTarget method LOCATE PubMed 
Membrane Plasma membrane (GO:0005886) 0.996 Experimental: experimental Organelle PubMed 
Membrane Connexon complex (GO:0005922) 0.996 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

P08571

Interaction Score
0.999

Q08380

(UniProtKB/Swiss-Prot/P) Details

Galectin-3-binding protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.8 Experimental: experimental eSLDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.999 Experimental: experimental eSLDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.999 Unknown: HDA GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.999 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.999 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.999 Unknown: HDA GO PubMed 
Extracellular Blood microparticle (GO:0072562) 0.999 Unknown: HDA GO PubMed 
Extracellular Extracellular matrix (GO:0031012) 0.999 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Membrane Membrane (GO:0016020) 0.86 Experimental: experimental MatrixDB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.3 Unknown: HDA GO PubMed 

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed 

P08571

Interaction Score
0.999

Q12841

(UniProtKB/Swiss-Prot/P) Details

Follistatin-related protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.86 Experimental: experimental eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.972 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.972 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum lumen (GO:0005788) 0.86 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.853 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.853 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.853 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.972 Unknown: HDA GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P08571

Interaction Score
0.997

Q9NP61

(UniProtKB/Swiss-Prot/P) Details

ADP-ribosylation factor GTPase-activating protein 3

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Organelle PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.8 Experimental: experimental eSLDB PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.972 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.972 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Golgi membrane (GO:0000139) 0.972 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.3 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

P08571

Interaction Score
0.987

Q68CP9

(UniProtKB/Swiss-Prot/P) Details

AT-rich interactive domain-containing protein 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.998 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.998 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.998 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.998 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Plasma membrane (GO:0005886) 0.96 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed 

P08571

Interaction Score
0.984

Q9UMF0

(UniProtKB/Swiss-Prot/P) Details

Intercellular adhesion molecule 5

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Plasma membrane (GO:0005886) 0.51 Unknown: traceable author statement GO PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.51 Unknown: traceable author statement GO PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed 

P08571

Interaction Score
0.978

Q15646

(UniProtKB/Swiss-Prot/P) Details

2'-5'-oligoadenylate synthase-like protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.998 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.998 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.998 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.998 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleolus (GO:0005730) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.3 Unknown: HDA GO PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed 

P08571

Interaction Score
0.972

O60237

(UniProtKB/Swiss-Prot/P) Details

Protein phosphatase 1 regulatory subunit 12B

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.999 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.999 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 0.79 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.79 Unknown: traceable author statement GO PubMed 
Cytosol Z disc (GO:0030018) 0.999 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol A band (GO:0031672) 0.999 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Actin cytoskeleton (GO:0015629) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Plasma membrane (GO:0005886) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed 

P08571

Interaction Score
0.97

Q9Y3D8

(UniProtKB/Swiss-Prot/P) Details

Adenylate kinase isoenzyme 6

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.94 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cytosol (GO:0005829) 0.94 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleolus (GO:0005730) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Cajal body (GO:0015030) 1 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.3 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P08571

Interaction Score
0.969

Q96LZ3

(UniProtKB/Swiss-Prot/P) Details

Calcineurin subunit B type 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.982 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.982 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.982 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Plasma membrane (GO:0005886) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

P08571

Interaction Score
0.967

Q9H6U6

(UniProtKB/Swiss-Prot/P) Details

Breast carcinoma-amplified sequence 3

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Cell leading edge (GO:0031252) 0.79 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.982 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleolus (GO:0005730) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleolus (GO:0005730) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Intermediate filament cytoskeleton (GO:0045111) 0.982 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Cytoplasmic microtubule (GO:0005881) 0.982 Predicted: inferred from sequence or structural similarity GO PubMed 
Nucleus Transcriptionally active chromatin (GO:0035327) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Cell periphery (GO:0071944) 0.79 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P08571

Interaction Score
0.957

A8MW92

(UniProtKB/Swiss-Prot/P) Details

PHD finger protein 20-like protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 0.987 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.987 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.987 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.987 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Plasma membrane (GO:0005886) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P08571

Interaction Score
0.94

Q14689

(UniProtKB/Swiss-Prot/P) Details

Disco-interacting protein 2 homolog A

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Cell surface (GO:0009986) 0.94 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.958 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.958 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.958 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Integral to membrane (GO:0016021) 0.94 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P08571

Interaction Score
0.938

E1CKY7

(UniProtKB/TrEmbl/P) Details

Protein phosphatase 1 regulatory subunit 12B

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Actin cytoskeleton (GO:0015629) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Plasma membrane (GO:0005886) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P08571

Interaction Score
0.93

F5H459

(UniProtKB/TrEmbl/P) Details

AP complex subunit sigma

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P08571

Interaction Score
0.92

A0A0A0MQS0

(UniProtKB/TrEmbl/P) Details

PHD finger protein 20-like protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Plasma membrane (GO:0005886) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P08571

Interaction Score
0.889

Q8N6I2

(UniProtKB/TrEmbl/P) Details

ICAM5 protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.7 Predicted: pTarget method LOCATE PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P08571

Interaction Score
0.882

Q8TCF0

(UniProtKB/TrEmbl/P) Details

LBP protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.7 Predicted: pTarget method LOCATE PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P08571

Interaction Score
0.86

O60566

(UniProtKB/Swiss-Prot/P) Details

Mitotic checkpoint serine/threonine-protein kinase BUB1 beta

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Ubiquitin ligase complex (GO:0000151) 1 Experimental: experimental Organelle PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Anaphase-promoting complex (GO:0005680) 1 Unknown: traceable author statement GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Experimental: experimental Organelle PubMed 
Cytosol Spindle midzone (GO:0051233) 1 Unknown: non-traceable author statement GO PubMed 
Cytosol Microtubule organizing center (GO:0005815) 1 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Chromosome (GO:0005694) 1 Experimental: experimental Organelle PubMed 
Nucleus Condensed nuclear chromosome kinetochore (GO:0000778) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Condensed chromosome kinetochore (GO:0000777) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Condensed chromosome outer kinetochore (GO:0000940) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Kinetochore (GO:0000776) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

P08571

Interaction Score
0.857

Q9Y616

(UniProtKB/Swiss-Prot/P) Details

Interleukin-1 receptor-associated kinase 3

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.996 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.996 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.996 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.996 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.8 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed 

P08571

Interaction Score
0.837

Q9UPZ3

(UniProtKB/Swiss-Prot/P) Details

Hermansky-Pudlak syndrome 5 protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.973 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.973 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol BLOC-2 complex (GO:0031084) 0.973 Predicted: inferred from physical interaction GO PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P08571

Interaction Score
0.8

Q9UQ84

(UniProtKB/Swiss-Prot/P) Details

Exonuclease 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nuclear body (GO:0016604) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear body (GO:0016604) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Plasma membrane (GO:0005886) 0.8 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed 

P08571

Interaction Score
0.776

H9U1J4

(UniProtKB/TrEmbl/P) Details

Gap junction protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P08571

Interaction Score
0.776

B3KWR9

(UniProtKB/TrEmbl/P) Details

Toll-like receptor

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P08571

Interaction Score
0.776

A0A0S2Z4S4

(UniProtKB/TrEmbl/P) Details

Toll-like receptor

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P08571

Interaction Score
0.722

Q2TUW9

(UniProtKB/TrEmbl/P) Details

Lactoferrin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.8 Experimental: experimental eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P08571

Interaction Score
0.688

B2R657

(UniProtKB/TrEmbl/P) Details

Annexin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.8 Experimental: experimental Human Proteinpedia PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P08571

Interaction Score
0.688

Q9H6R7

(UniProtKB/Swiss-Prot/P) Details

WD repeat and coiled-coil-containing protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleolus (GO:0005730) 0.94 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

P08571

Interaction Score
0.688

Q16594

(UniProtKB/Swiss-Prot/P) Details

Transcription initiation factor TFIID subunit 9

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Pre-snoRNP complex (GO:0070761) 0.8 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Unknown: traceable author statement GO PubMed 
Nucleus MLL1 complex (GO:0071339) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Transcription factor TFIID complex (GO:0005669) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Transcription factor TFTC complex (GO:0033276) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus SAGA complex (GO:0000124) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus STAGA complex (GO:0030914) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus PCAF complex (GO:0000125) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed 

P08571

Interaction Score
0

P52435

(UniProtKB/Swiss-Prot/P) Details

DNA-directed RNA polymerase II subunit RPB11-a

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Unknown: traceable author statement GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus DNA-directed RNA polymerase II, core complex (GO:0005665) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus RNA polymerase complex (GO:0030880) 1 Experimental: experimental Organelle PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

P08571

Interaction Score
0

Q569J5

(UniProtKB/TrEmbl/P) Details

SVIL protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.91 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.91 Predicted: pTarget method LOCATE PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P08571

Interaction Score
0

Q05D99

(UniProtKB/TrEmbl/P) Details

BCAS3 protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P08571

Interaction Score
0

K7ESE9

(UniProtKB/TrEmbl/P) Details

Breast carcinoma-amplified sequence 3

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleolus (GO:0005730) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P08571

Interaction Score
0

Q96BD5

(UniProtKB/Swiss-Prot/P) Details

PHD finger protein 21A

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.987 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.987 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.987 Unknown: traceable author statement GO PubMed 
Nucleus Histone deacetylase complex (GO:0000118) 0.987 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P08571

Interaction Score
0

H0Y9L7

(UniProtKB/TrEmbl/P) Details

Transcription initiation factor TFIID subunit 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P08571

Interaction Score
0

P21675

(UniProtKB/Swiss-Prot/P) Details

Transcription initiation factor TFIID subunit 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleolus (GO:0005730) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus MLL1 complex (GO:0071339) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Transcription factor complex (GO:0005667) 1 Predicted: inferred from physical interaction GO PubMed 
Nucleus Transcription factor TFIID complex (GO:0005669) 1 Unknown: traceable author statement GO PubMed 
Nucleus Nuclear chromatin (GO:0000790) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

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ComPPI is published in Nucleic Acids Research Database Issue 2015