P18669

Phosphoglycerate mutase 1    //   UniProt Profile 

Custom Settings: Use these controls to filter the data displayed on this page. The parameters apply to both the query protein and its interactors. Details







The (filtered) results are available for download, see the help for details. Download The Results

Species

H. sapiens

Number of Interactions

78 / 109

Average Interaction Score

0.927

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Myelin sheath (GO:0043209) 0.902 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.992 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.992 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.992 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.86 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Secretory granule lumen (GO:0034774) 0.3 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.86 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.86 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.902 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 0.902 Experimental: experimental MatrixDB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.992 Unknown: HDA GO PubMed 

First-Neighbour Network Visualization

Toggle Display

The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

P18669

Interaction Score
1

P00441

(UniProtKB/Swiss-Prot/P) Details

Superoxide dismutase [Cu-Zn]

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Myelin sheath (GO:0043209) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Neuronal cell body (GO:0043025) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.902 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrial matrix (GO:0005759) 0.902 Unknown: non-traceable author statement GO PubMed 
Mitochondrion Mitochondrial intermembrane space (GO:0005758) 0.902 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 0.998 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.998 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.998 Experimental: inferred from direct assay GO PubMed 
Nucleus Macromolecular complex (GO:0032991) 0.998 Experimental: inferred from direct assay GO PubMed 
Cytosol Lysosome (GO:0005764) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Peroxisome (GO:0005777) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Secretory-pathway Cytoplasmic vesicle (GO:0031410) 0.86 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Dense core granule (GO:0031045) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Membrane Dendrite cytoplasm (GO:0032839) 0.999 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.994 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular space (GO:0005615) 0.994 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular matrix (GO:0031012) 0.994 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular matrix (GO:0031012) 0.994 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.999 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.999 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
1

P04406

(UniProtKB/Swiss-Prot/P) Details

Glyceraldehyde-3-phosphate dehydrogenase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
N/A GAIT complex (GO:0097452) 0.8 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Lipid particle (GO:0005811) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 1 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 0.988 Predicted: inferred from sequence or structural similarity GO PubMed 
Nucleus Nucleus (GO:0005634) 0.988 Experimental: experimental Human Proteinpedia PubMed 
Nucleus Nuclear membrane (GO:0031965) 0.988 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Microtubule cytoskeleton (GO:0015630) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.96 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular matrix (GO:0031012) 0.96 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.972 Unknown: HDA GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.972 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.972 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Vesicle (GO:0031982) 1 Unknown: HDA GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
1

P05067

(UniProtKB/Swiss-Prot/P) Details

Amyloid-beta A4 protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 1 Experimental: experimental eSLDB PubMed 
Membrane Cell surface (GO:0009986) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Coated pit (GO:0005905) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Apical part of cell (GO:0045177) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Unknown: traceable author statement GO PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.96 Experimental: experimental eSLDB PubMed 
Nucleus Nuclear envelope lumen (GO:0005641) 0.96 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 1 Experimental: experimental eSLDB PubMed 
Secretory-pathway Rough endoplasmic reticulum (GO:0005791) 1 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Smooth endoplasmic reticulum (GO:0005790) 1 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Endoplasmic reticulum lumen (GO:0005788) 1 Unknown: traceable author statement GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 1 Experimental: experimental eSLDB PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Golgi lumen (GO:0005796) 1 Unknown: traceable author statement GO PubMed 
Secretory-pathway Trans-Golgi network membrane (GO:0032588) 1 Unknown: traceable author statement GO PubMed 
Secretory-pathway Endosome (GO:0005768) 1 Experimental: experimental eSLDB PubMed 
Secretory-pathway Endosome (GO:0005768) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endosome lumen (GO:0031904) 1 Unknown: traceable author statement GO PubMed 
Cytosol Lysosome (GO:0005764) 1 Experimental: experimental eSLDB PubMed 
Secretory-pathway Platelet alpha granule lumen (GO:0031093) 1 Unknown: traceable author statement GO PubMed 
Secretory-pathway ER to Golgi transport vesicle (GO:0030134) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Spindle midzone (GO:0051233) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Astrocyte projection (GO:0097449) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Dendritic shaft (GO:0043198) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Dendritic spine (GO:0043197) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Axon (GO:0030424) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Main axon (GO:0044304) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Ciliary rootlet (GO:0035253) 1 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.98 Experimental: experimental eSLDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.98 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.98 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular space (GO:0005615) 0.98 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 1 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Membrane raft (GO:0045121) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: pTarget method LOCATE PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Integral to plasma membrane (GO:0005887) 1 Unknown: traceable author statement GO PubMed 
Membrane Receptor complex (GO:0043235) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Vesicle (GO:0031982) 1 Experimental: experimental eSLDB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 
Membrane Cell-cell junction (GO:0005911) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Synapse (GO:0045202) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Neuromuscular junction (GO:0031594) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Presynaptic active zone (GO:0048786) 1 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P18669

Interaction Score
1

P06733

(UniProtKB/Swiss-Prot/P) Details

Alpha-enolase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Cell surface (GO:0009986) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Phosphopyruvate hydratase complex (GO:0000015) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.958 Unknown: inferred by curator GO PubMed 
Nucleus Nucleus (GO:0005634) 0.958 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 0.958 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol M band (GO:0031430) 1 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.86 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular space (GO:0005615) 0.86 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Membrane (GO:0016020) 1 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
1

Q99569

(UniProtKB/Swiss-Prot/P) Details

Plakophilin-4

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Midbody (GO:0030496) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.91 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.91 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cornified envelope (GO:0001533) 1 Unknown: traceable author statement GO PubMed 
Cytosol Mitotic spindle (GO:0072686) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Spindle midzone (GO:0051233) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Spindle pole (GO:0000922) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Postsynaptic density (GO:0014069) 1 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Internal side of plasma membrane (GO:0009898) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Cell junction (GO:0030054) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Cell junction (GO:0030054) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Cell-cell junction (GO:0005911) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Cell-cell contact zone (GO:0044291) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Desmosome (GO:0030057) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P18669

Interaction Score
1

O00429

(UniProtKB/Swiss-Prot/P) Details

Dynamin-1-like protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Coated pit (GO:0005905) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.988 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.988 Predicted: PAML algorithm PA-GOSUB PubMed 
Mitochondrion Mitochondrial outer membrane (GO:0005741) 0.988 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Macromolecular complex (GO:0032991) 0.94 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.997 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.997 Experimental: experimental Organelle PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 0.997 Unknown: traceable author statement GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.997 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi membrane (GO:0000139) 0.997 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Peroxisome (GO:0005777) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Synaptic vesicle membrane (GO:0030672) 0.997 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Microtubule (GO:0005874) 1 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.51 Unknown: HDA GO PubMed 
Membrane Cell junction (GO:0030054) 0.51 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

P18669

Interaction Score
1

Q15051

(UniProtKB/Swiss-Prot/P) Details

IQ calmodulin-binding motif-containing protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.94 Experimental: inferred from direct assay GO PubMed 
Cytosol Microtubule cytoskeleton (GO:0015630) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Microtubule cytoskeleton (GO:0015630) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Mitotic spindle (GO:0072686) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Centrosome (GO:0005813) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Centriole (GO:0005814) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Photoreceptor connecting cilium (GO:0032391) 0.86 Experimental: inferred from direct assay GO PubMed 
Membrane Photoreceptor outer segment (GO:0001750) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Intercellular bridge (GO:0045171) 0.96 Experimental: inferred from direct assay GO PubMed 
Extracellular Intercellular bridge (GO:0045171) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

P18669

Interaction Score
1

Q14203

(UniProtKB/Swiss-Prot/P) Details

Dynactin subunit 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Cell leading edge (GO:0031252) 0.931 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Retromer complex (GO:0030904) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Neuronal cell body (GO:0043025) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Cell cortex (GO:0005938) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear envelope (GO:0005635) 0.96 Experimental: inferred from direct assay GO PubMed 
Cytosol Intermediate filament cytoskeleton (GO:0045111) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Intermediate filament cytoskeleton (GO:0045111) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Spindle (GO:0005819) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Spindle pole (GO:0000922) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Microtubule associated complex (GO:0005875) 1 Experimental: inferred from mutant phenotype GO PubMed 
Cytosol Dynein complex (GO:0030286) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Dynactin complex (GO:0005869) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Centrosome (GO:0005813) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Centrosome (GO:0005813) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Centriole (GO:0005814) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Microtubule (GO:0005874) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Microtubule plus end (GO:0035371) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Kinetochore (GO:0000776) 0.96 Experimental: inferred from direct assay GO PubMed 
Membrane Neuron projection (GO:0043005) 0.931 Experimental: inferred from direct assay GO PubMed 
Membrane Axon (GO:0030424) 0.931 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.931 Unknown: HDA GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P18669

Interaction Score
1

Q04760

(UniProtKB/Swiss-Prot/P) Details

Lactoylglutathione lyase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.999 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Unknown: traceable author statement GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytosol (GO:0005829) 0.999 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 0.96 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Plasma membrane (GO:0005886) 0.96 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.999 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
1

P15121

(UniProtKB/Swiss-Prot/P) Details

Aldose reductase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Schmidt-Lanterman incisure (GO:0043220) 0.952 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.996 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.996 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.996 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 0.996 Unknown: inferred from electronic annotation GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.96 Experimental: inferred from direct assay GO PubMed 
Cytosol Mast cell granule (GO:0042629) 0.996 Unknown: inferred from electronic annotation GO PubMed 
Membrane Schwann cell microvillus (GO:0097454) 0.952 Unknown: inferred from electronic annotation GO PubMed 
Membrane Cell projection cytoplasm (GO:0032838) 0.952 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular space (GO:0005615) 0.3 Unknown: traceable author statement GO PubMed 
Membrane Membrane (GO:0016020) 0.952 Experimental: experimental MatrixDB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.996 Unknown: HDA GO PubMed 
Membrane Paranodal junction (GO:0033010) 0.952 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
1

P62136

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Protein phosphatase type 1 complex (GO:0000164) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol PTW/PP1 phosphatase complex (GO:0072357) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Perikaryon (GO:0043204) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Glycogen granule (GO:0042587) 1 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Human Proteinpedia PubMed 
Nucleus Nucleolus (GO:0005730) 1 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nuclear chromosome, telomeric region (GO:0000784) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Dendritic spine (GO:0043197) 0.994 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.994 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.994 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 
Membrane Cell-cell adherens junction (GO:0005913) 0.994 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P18669

Interaction Score
1

P13569

(UniProtKB/Swiss-Prot/P) Details

Cystic fibrosis transmembrane conductance regulator

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Cell surface (GO:0009986) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.972 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.972 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Predicted: inferred from sequence or structural similarity GO PubMed 
Nucleus Macromolecular complex (GO:0032991) 0.94 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Endoplasmic reticulum Sec complex (GO:0031205) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi-associated vesicle membrane (GO:0030660) 1 Unknown: traceable author statement GO PubMed 
Secretory-pathway Recycling endosome (GO:0055037) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Recycling endosome membrane (GO:0055038) 1 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Early endosome (GO:0005769) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Early endosome membrane (GO:0031901) 1 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Endosome membrane (GO:0010008) 1 Unknown: traceable author statement GO PubMed 
Cytosol Lysosomal membrane (GO:0005765) 0.972 Unknown: traceable author statement GO PubMed 
Secretory-pathway Clathrin coated vesicle membrane (GO:0030665) 1 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Chloride channel complex (GO:0034707) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to plasma membrane (GO:0005887) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Apical plasma membrane (GO:0016324) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
1

P62491

(UniProtKB/Swiss-Prot/P) Details

Ras-related protein Rab-11A

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cleavage furrow (GO:0032154) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytosol (GO:0005829) 1 Unknown: traceable author statement GO PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Macromolecular complex (GO:0032991) 0.8 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 1 Unknown: HDA GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Trans-Golgi network (GO:0005802) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Recycling endosome (GO:0055037) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Secretory-pathway Recycling endosome membrane (GO:0055038) 1 Unknown: traceable author statement GO PubMed 
Secretory-pathway Multivesicular body (GO:0005771) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Cytoplasmic vesicle (GO:0031410) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Cytoplasmic vesicle membrane (GO:0030659) 1 Unknown: traceable author statement GO PubMed 
Secretory-pathway Phagocytic vesicle (GO:0045335) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Transport vesicle (GO:0030133) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Kinetochore microtubule (GO:0005828) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Spindle pole (GO:0000922) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Microtubule organizing center (GO:0005815) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Microtubule organizing center (GO:0005815) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Centrosome (GO:0005813) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Axon (GO:0030424) 0.79 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.79 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Vesicle (GO:0031982) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
1

P63104

(UniProtKB/Swiss-Prot/P) Details

14-3-3 protein zeta/delta

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.999 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Unknown: traceable author statement GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.999 Unknown: traceable author statement GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.902 Unknown: HDA GO PubMed 
Nucleus Nucleus (GO:0005634) 0.902 Experimental: experimental Human Proteinpedia PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.902 Unknown: traceable author statement GO PubMed 
Secretory-pathway Melanosome (GO:0042470) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 0.999 Experimental: experimental Human Proteinpedia PubMed 
Extracellular Extracellular space (GO:0005615) 0.51 Unknown: HDA GO PubMed 
Extracellular Blood microparticle (GO:0072562) 0.51 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 0.86 Experimental: experimental MatrixDB PubMed 
Cytosol Vesicle (GO:0031982) 0.999 Unknown: HDA GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.999 Unknown: HDA GO PubMed 
Membrane Focal adhesion (GO:0005925) 0.86 Unknown: HDA GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P18669

Interaction Score
1

P13929

(UniProtKB/Swiss-Prot/P) Details

Beta-enolase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Phosphopyruvate hydratase complex (GO:0000015) 1 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.86 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular space (GO:0005615) 0.86 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 0.998 Experimental: inferred from direct assay GO PubMed 
Membrane Membrane (GO:0016020) 0.998 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.998 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.998 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
1

P09104

(UniProtKB/Swiss-Prot/P) Details

Gamma-enolase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Photoreceptor inner segment (GO:0001917) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Membrane Myelin sheath (GO:0043209) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Perikaryon (GO:0043204) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Phosphopyruvate hydratase complex (GO:0000015) 1 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.86 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular space (GO:0005615) 0.86 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 0.999 Experimental: inferred from direct assay GO PubMed 
Membrane Membrane (GO:0016020) 0.999 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.999 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
1

Q01469

(UniProtKB/Swiss-Prot/P) Details

Fatty acid-binding protein 5

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.994 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.994 Unknown: traceable author statement GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.994 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.994 Unknown: traceable author statement GO PubMed 
Cytosol Cytosol (GO:0005829) 0.994 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.86 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.86 Unknown: traceable author statement GO PubMed 
Secretory-pathway Secretory granule membrane (GO:0030667) 0.51 Unknown: traceable author statement GO PubMed 
Secretory-pathway Azurophil granule lumen (GO:0035578) 0.51 Unknown: traceable author statement GO PubMed 
Membrane Postsynaptic density (GO:0014069) 0.999 Predicted: inferred from sequence or structural similarity GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.3 Unknown: traceable author statement GO PubMed 
Membrane Membrane (GO:0016020) 0.999 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.999 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.994 Unknown: HDA GO PubMed 
Membrane Cell junction (GO:0030054) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Membrane Synapse (GO:0045202) 0.999 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Postsynaptic membrane (GO:0045211) 0.999 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
1

P54105

(UniProtKB/Swiss-Prot/P) Details

Methylosome subunit pICln

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol PICln-Sm protein complex (GO:0034715) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Methylosome (GO:0034709) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Microtubule cytoskeleton (GO:0015630) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Plasma membrane (GO:0005886) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.86 Experimental: experimental Organelle PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
1

P09972

(UniProtKB/Swiss-Prot/P) Details

Fructose-bisphosphate aldolase C

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.999 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytosol (GO:0005829) 0.999 Unknown: traceable author statement GO PubMed 
Cytosol Cytosol (GO:0005829) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Fibrillar center (GO:0001650) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Secretory granule lumen (GO:0034774) 0.3 Unknown: traceable author statement GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 0.999 Unknown: inferred by curator GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.3 Unknown: traceable author statement GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.999 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
1

P15056

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein kinase B-raf

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Intracellular (GO:0005622) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.79 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.79 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.7 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
1

P60174

(UniProtKB/Swiss-Prot/P) Details

Triosephosphate isomerase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.996 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.996 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 0.996 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.996 Predicted: inferred from biological aspect of ancestor GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 0.86 Unknown: HDA GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.86 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular space (GO:0005615) 0.3 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.996 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
1

P11413

(UniProtKB/Swiss-Prot/P) Details

Glucose-6-phosphate 1-dehydrogenase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.7 Predicted: pTarget method LOCATE PubMed 
Cytosol Microtubule organizing center (GO:0005815) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.86 Unknown: HDA GO PubMed 
Membrane Internal side of plasma membrane (GO:0009898) 0.86 Experimental: inferred from direct assay GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
1

P10599

(UniProtKB/Swiss-Prot/P) Details

Thioredoxin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleolus (GO:0005730) 0.992 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
1

P12956

(UniProtKB/Swiss-Prot/P) Details

X-ray repair cross-complementing protein 6

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.958 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.958 Unknown: traceable author statement GO PubMed 
Cytosol Nonhomologous end joining complex (GO:0070419) 0.958 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleolus (GO:0005730) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Transcription factor complex (GO:0005667) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Macromolecular complex (GO:0032991) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Protein-DNA complex (GO:0032993) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear telomere cap complex (GO:0000783) 1 Unknown: traceable author statement GO PubMed 
Nucleus Ku70:Ku80 complex (GO:0043564) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Secretory granule lumen (GO:0034774) 0.3 Unknown: traceable author statement GO PubMed 
Nucleus Nuclear chromosome, telomeric region (GO:0000784) 1 Unknown: HDA GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.86 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.86 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.86 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 0.86 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

P18669

Interaction Score
1

P25788

(UniProtKB/Swiss-Prot/P) Details

Proteasome subunit alpha type-3

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Unknown: traceable author statement GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytosol (GO:0005829) 1 Unknown: traceable author statement GO PubMed 
Cytosol Proteasome complex (GO:0000502) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Proteasome core complex (GO:0005839) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Proteasome core complex, alpha-subunit complex (GO:0019773) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Nucleus Nucleus (GO:0005634) 0.902 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 0.902 Experimental: experimental Organelle PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.902 Unknown: traceable author statement GO PubMed 
Cytosol Microtubule cytoskeleton (GO:0015630) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Intercellular bridge (GO:0045171) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 
Membrane Synapse (GO:0045202) 0.3 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
1

P61970

(UniProtKB/Swiss-Prot/P) Details

Nuclear transport factor 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.998 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.998 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.998 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear membrane (GO:0031965) 0.979 Predicted: inferred from sequence or structural similarity GO PubMed 
Nucleus Nuclear outer membrane (GO:0005640) 0.979 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nuclear inner membrane (GO:0005637) 0.979 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nuclear pore central transport channel (GO:0044613) 0.979 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.979 Experimental: inferred from direct assay GO PubMed 
Cytosol Microtubule cytoskeleton (GO:0015630) 0.998 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.998 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.999

P49703

(UniProtKB/Swiss-Prot/P) Details

ADP-ribosylation factor-like protein 4D

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.96 Experimental: inferred from direct assay GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.79 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleolus (GO:0005730) 0.79 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.8 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.999

Q15907

(UniProtKB/Swiss-Prot/P) Details

Ras-related protein Rab-11B

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.999 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytosol (GO:0005829) 0.999 Unknown: traceable author statement GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.997 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Recycling endosome (GO:0055037) 0.997 Predicted: inferred from sequence or structural similarity GO PubMed 
Secretory-pathway Recycling endosome membrane (GO:0055038) 0.997 Unknown: traceable author statement GO PubMed 
Secretory-pathway Phagocytic vesicle (GO:0045335) 0.997 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Phagocytic vesicle membrane (GO:0030670) 0.997 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Synaptic vesicle (GO:0008021) 0.997 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Microtubule organizing center (GO:0005815) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.79 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.999 Unknown: HDA GO PubMed 
Membrane Cell junction (GO:0030054) 0.79 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.999

P04629

(UniProtKB/Swiss-Prot/P) Details

High affinity nerve growth factor receptor

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Cell surface (GO:0009986) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Neuronal cell body (GO:0043025) 0.897 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytosol (GO:0005829) 0.897 Unknown: unspecified method The Human Protein Atlas PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.897 Unknown: unspecified method The Human Protein Atlas PubMed 
Nucleus Macromolecular complex (GO:0032991) 0.7 Predicted: inferred from sequence or structural similarity GO PubMed 
Secretory-pathway Endosome (GO:0005768) 0.994 Experimental: experimental eSLDB PubMed 
Secretory-pathway Endosome (GO:0005768) 0.994 Unknown: traceable author statement GO PubMed 
Secretory-pathway Early endosome (GO:0005769) 0.994 Predicted: inferred from sequence or structural similarity GO PubMed 
Secretory-pathway Late endosome membrane (GO:0031902) 0.994 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Early endosome membrane (GO:0031901) 0.994 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Late endosome (GO:0005770) 0.994 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Lysosome (GO:0005764) 0.897 Predicted: pTarget method LOCATE PubMed 
Membrane Dendrite (GO:0030425) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Axon (GO:0030424) 1 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Predicted: SVM decision tree eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to plasma membrane (GO:0005887) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Receptor complex (GO:0043235) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.999

P09622

(UniProtKB/Swiss-Prot/P) Details

Dihydrolipoyl dehydrogenase, mitochondrial

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Myelin sheath (GO:0043209) 0.51 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Pyruvate dehydrogenase complex (GO:0045254) 0.96 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.999 Predicted: SVM decision tree eSLDB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.999 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.999 Experimental: experimental Organelle PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.999 Predicted: PAML algorithm PA-GOSUB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Mitochondrion Mitochondrial matrix (GO:0005759) 0.999 Unknown: traceable author statement GO PubMed 
Cytosol Oxoglutarate dehydrogenase complex (GO:0045252) 0.96 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Experimental: experimental Human Proteinpedia PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.992 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Acrosomal matrix (GO:0043159) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Membrane Motile cilium (GO:0031514) 0.51 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.999

Q96NS5

(UniProtKB/Swiss-Prot/P) Details

Ankyrin repeat and SOCS box protein 16

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Ubiquitin ligase complex (GO:0000151) 0.998 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.998 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.998 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.998 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytoplasm (GO:0005737) 0.998 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.998 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Focal adhesion (GO:0005925) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.999

Q9NX55

(UniProtKB/Swiss-Prot/P) Details

Huntingtin-interacting protein K

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.992 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Macromolecular complex (GO:0032991) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Microtubule cytoskeleton (GO:0015630) 0.992 Experimental: inferred from direct assay GO PubMed 
Cytosol Microtubule cytoskeleton (GO:0015630) 0.992 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.999

P04818

(UniProtKB/Swiss-Prot/P) Details

Thymidylate synthase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.958 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.958 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.958 Unknown: traceable author statement GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.992 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrial matrix (GO:0005759) 0.992 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrial inner membrane (GO:0005743) 0.992 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.86 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleolus (GO:0005730) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.999

Q8IV45

(UniProtKB/Swiss-Prot/P) Details

UNC5C-like protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.958 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.958 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Centrosome (GO:0005813) 0.958 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Membrane (GO:0016020) 0.958 Experimental: inferred from direct assay GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.958 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.958 Predicted: pTarget method LOCATE PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.999

P15336

(UniProtKB/Swiss-Prot/P) Details

Cyclic AMP-dependent transcription factor ATF-2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.94 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.94 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrial outer membrane (GO:0005741) 0.8 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Site of double-strand break (GO:0035861) 1 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.999

P37802

(UniProtKB/Swiss-Prot/P) Details

Transgelin-2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.996 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.996 Unknown: traceable author statement GO PubMed 
Cytosol Cytosol (GO:0005829) 0.996 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: pTarget method LOCATE PubMed 
Cytosol Actin cytoskeleton (GO:0015629) 0.996 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.3 Unknown: traceable author statement GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 
Cytosol Vesicle (GO:0031982) 0.996 Unknown: HDA GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.996 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.999

Q9NRC8

(UniProtKB/Swiss-Prot/P) Details

NAD-dependent protein deacetylase sirtuin-7

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.972 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.972 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.972 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleolus (GO:0005730) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Fibrillar center (GO:0001650) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleolus organizer region (GO:0005731) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.998

Q9GZX7

(UniProtKB/Swiss-Prot/P) Details

Single-stranded DNA cytosine deaminase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.992 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.992 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Exosome (RNase complex) (GO:0000178) 0.992 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.998

P11172

(UniProtKB/Swiss-Prot/P) Details

Uridine 5'-monophosphate synthase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.997 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.997 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytoplasm (GO:0005737) 0.997 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.997 Unknown: traceable author statement GO PubMed 
Cytosol Cytosol (GO:0005829) 0.997 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.8 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.998

J3KN38

(UniProtKB/TrEmbl/P) Details

Methylosome subunit pICln

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.998 Experimental: experimental eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.998 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.96 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Cytoskeleton (GO:0005856) 0.998 Experimental: experimental eSLDB PubMed 
Cytosol Microtubule cytoskeleton (GO:0015630) 0.998 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.998

O15264

(UniProtKB/Swiss-Prot/P) Details

Mitogen-activated protein kinase 13

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.996 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.996 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.996 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.996 Unknown: traceable author statement GO PubMed 
Cytosol Cytosol (GO:0005829) 0.996 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.988 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Nucleus (GO:0005634) 0.988 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleolus (GO:0005730) 0.988 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.998

Q00987

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase Mdm2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.972 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.972 Experimental: inferred from mutant phenotype GO PubMed 
Cytosol Cytosol (GO:0005829) 0.972 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleolus (GO:0005730) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear body (GO:0016604) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Macromolecular complex (GO:0032991) 1 Experimental: inferred from mutant phenotype GO PubMed 
Secretory-pathway Endocytic vesicle membrane (GO:0030666) 0.3 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.51 Unknown: traceable author statement GO PubMed 
Membrane Synapse (GO:0045202) 0.51 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.997

O43175

(UniProtKB/Swiss-Prot/P) Details

D-3-phosphoglycerate dehydrogenase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Myelin sheath (GO:0043209) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.971 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.971 Unknown: traceable author statement GO PubMed 
Cytosol Cytosol (GO:0005829) 0.971 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Plasma membrane (GO:0005886) 0.86 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.971 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.997

P36957

(UniProtKB/Swiss-Prot/P) Details

Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Myelin sheath (GO:0043209) 0.51 Unknown: inferred from electronic annotation GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.996 Predicted: SVM decision tree eSLDB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.996 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.996 Predicted: pTarget method LOCATE PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.996 Predicted: PAML algorithm PA-GOSUB PubMed 
Mitochondrion Mitochondrial matrix (GO:0005759) 0.996 Unknown: traceable author statement GO PubMed 
Cytosol Oxoglutarate dehydrogenase complex (GO:0045252) 0.8 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.86 Unknown: HDA GO PubMed 
Nucleus Nucleus (GO:0005634) 0.86 Experimental: experimental Human Proteinpedia PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.51 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.997

P15259

(UniProtKB/Swiss-Prot/P) Details

Phosphoglycerate mutase 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.987 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.987 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cytosol (GO:0005829) 0.987 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.86 Unknown: HDA GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.86 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.987 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.997

Q14258

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin/ISG15 ligase TRIM25

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.988 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.988 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.988 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nuclear body (GO:0016604) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear body (GO:0016604) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.997

Q8TCT1

(UniProtKB/Swiss-Prot/P) Details

Phosphoethanolamine/phosphocholine phosphatase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.958 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.958 Unknown: traceable author statement GO PubMed 
Cytosol Actin cytoskeleton (GO:0015629) 0.958 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular membrane-bounded organelle (GO:0065010) 0.902 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular matrix (GO:0031012) 0.902 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular matrix (GO:0031012) 0.902 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.996

P31040

(UniProtKB/Swiss-Prot/P) Details

Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Myelin sheath (GO:0043209) 0.958 Unknown: inferred from electronic annotation GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 1 Predicted: SVM decision tree eSLDB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 1 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 1 Predicted: pTarget method LOCATE PubMed 
Mitochondrion Mitochondrion (GO:0005739) 1 Experimental: experimental Organelle PubMed 
Mitochondrion Mitochondrion (GO:0005739) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Mitochondrion Mitochondrial inner membrane (GO:0005743) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Mitochondrion Mitochondrial respiratory chain complex II (GO:0005749) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Nucleus Nucleolus (GO:0005730) 0.8 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.958 Experimental: experimental eSLDB PubMed 
Membrane Plasma membrane succinate dehydrogenase complex (GO:0045282) 0.958 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.995

P12004

(UniProtKB/Swiss-Prot/P) Details

Proliferating cell nuclear antigen

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol PCNA complex (GO:0043626) 0.972 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nuclear body (GO:0016604) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear body (GO:0016604) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus PCNA-p21 complex (GO:0070557) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Centrosome (GO:0005813) 0.972 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear chromosome, telomeric region (GO:0000784) 1 Unknown: HDA GO PubMed 
Nucleus Nuclear replication fork (GO:0043596) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Replication fork (GO:0005657) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Replisome (GO:0030894) 1 Unknown: traceable author statement GO PubMed 
Nucleus DNA replication factor C complex (GO:0005663) 1 Unknown: traceable author statement GO PubMed 
Nucleus Chromatin (GO:0000785) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.972 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.993

P49715

(UniProtKB/Swiss-Prot/P) Details

CCAAT/enhancer-binding protein alpha

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.96 Experimental: inferred from direct assay GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleolus (GO:0005730) 1 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus RNA polymerase II transcription factor complex (GO:0090575) 1 Experimental: inferred from mutant phenotype GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.992

G8JLD5

(UniProtKB/TrEmbl/P) Details

Dynamin-1-like protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.988 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytosol (GO:0005829) 0.988 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.988 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.985

P32119

(UniProtKB/Swiss-Prot/P) Details

Peroxiredoxin-2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.994 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.994 Unknown: traceable author statement GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.994 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 0.994 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.994 Unknown: traceable author statement GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.994 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.985

E9PJF4

(UniProtKB/TrEmbl/P) Details

Methylosome subunit pICln

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Microtubule cytoskeleton (GO:0015630) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.985

E9PMI6

(UniProtKB/TrEmbl/P) Details

Methylosome subunit pICln

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Microtubule cytoskeleton (GO:0015630) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.979

Q96DX5

(UniProtKB/Swiss-Prot/P) Details

Ankyrin repeat and SOCS box protein 9

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.981 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.981 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytoplasm (GO:0005737) 0.981 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.981 Unknown: traceable author statement GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.3 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.973

P42785

(UniProtKB/Swiss-Prot/P) Details

Lysosomal Pro-X carboxypeptidase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Basal part of cell (GO:0045178) 0.971 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Lysosome (GO:0005764) 0.971 Experimental: experimental eSLDB PubMed 
Cytosol Lysosome (GO:0005764) 0.971 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Plasma membrane (GO:0005886) 0.3 Unknown: traceable author statement GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.971 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.972

P12532

(UniProtKB/Swiss-Prot/P) Details

Creatine kinase U-type, mitochondrial

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Mitochondrion Mitochondrion (GO:0005739) 0.971 Experimental: experimental eSLDB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.971 Unknown: traceable author statement GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.971 Predicted: PAML algorithm PA-GOSUB PubMed 
Mitochondrion Mitochondrial inner membrane (GO:0005743) 0.971 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.961

Q9UII6

(UniProtKB/Swiss-Prot/P) Details

Dual specificity protein phosphatase 13 isoform B

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.952

A0A2R8Y8E0

(UniProtKB/TrEmbl/P) Details

Serine/threonine-protein kinase B-raf

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.95

Q53HE2

(UniProtKB/TrEmbl/P) Details

Triosephosphate isomerase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: pTarget method LOCATE PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.941

G3XA89

(UniProtKB/TrEmbl/P) Details

E3 ubiquitin-protein ligase Mdm2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.902

P05412

(UniProtKB/Swiss-Prot/P) Details

Transcription factor AP-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Transcriptional repressor complex (GO:0017053) 1 Unknown: inferred from electronic annotation GO PubMed 
Nucleus AP1 complex (GO:0035976) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Chromosome (GO:0005694) 1 Experimental: experimental Organelle PubMed 
Nucleus Nuclear chromosome (GO:0000228) 1 Unknown: traceable author statement GO PubMed 
Nucleus Nuclear euchromatin (GO:0005719) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.877

Q6B8I1

(UniProtKB/Swiss-Prot/P) Details

Dual specificity protein phosphatase 13 isoform A

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.863

D6RFM5

(UniProtKB/TrEmbl/P) Details

Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Mitochondrion Mitochondrion (GO:0005739) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.86

Q9BSM1

(UniProtKB/Swiss-Prot/P) Details

Polycomb group RING finger protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus PcG protein complex (GO:0031519) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.722

V9HWC9

(UniProtKB/TrEmbl/P) Details

Superoxide dismutase [Cu-Zn]

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.694

Q53Y97

(UniProtKB/TrEmbl/P) Details

Thymidylate synthetase, isoform CRA_f

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.694

Q6FHV6

(UniProtKB/TrEmbl/P) Details

ENO2 protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.688

B1AHC9

(UniProtKB/TrEmbl/P) Details

X-ray repair cross-complementing protein 6

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.688

A7UKX8

(UniProtKB/TrEmbl/P) Details

E3 ubiquitin-protein ligase Mdm2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.688

X5DR71

(UniProtKB/TrEmbl/P) Details

Tyrosine-protein kinase receptor

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.688

A0A024QZ30

(UniProtKB/TrEmbl/P) Details

Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.688

A0A024R730

(UniProtKB/TrEmbl/P) Details

Cystic fibrosis transmembrane conductance regulator

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.602

Q96DS0

(UniProtKB/TrEmbl/P) Details

MDM2 variant FB55

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.56

E9PEX6

(UniProtKB/TrEmbl/P) Details

Dihydrolipoyl dehydrogenase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Mitochondrion Mitochondrion (GO:0005739) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.49

Q546Y9

(UniProtKB/TrEmbl/P) Details

AID

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.49

Q6QJ80

(UniProtKB/TrEmbl/P) Details

Activation-induced cytidine deaminase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P18669

Interaction Score
0.49

Q7Z599

(UniProtKB/TrEmbl/P) Details

Activation-induced cytidine deaminase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

⇦ Back to the Search Page
⇦ Back to Starting Page

ComPPI is published in Nucleic Acids Research Database Issue 2015