P20800

Endothelin-2    //   UniProt Profile 

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Species

 H. sapiens

Number of Interactions

 3 / 3

Average Interaction Score

 0.996

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.8 Experimental: experimental eSLDB PubMed 
Cytosol Intracellular (GO:0005622) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytosol (GO:0005829) 0.86 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.987 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.987 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular region (GO:0005576) 0.987 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.987 Experimental: inferred from direct assay GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

P20800

Interaction Score
0.998

P23946

(UniProtKB/Swiss-Prot/P) Details

Chymase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.94 Predicted: SVM decision tree eSLDB PubMed 
Secretory-pathway Secretory granule (GO:0030141) 0.7 Predicted: inferred from biological aspect of ancestor GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Unknown: HDA GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular matrix (GO:0031012) 0.958 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 
Cytosol Vesicle (GO:0031982) 0.94 Experimental: experimental eSLDB PubMed 

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed 

P20800

Interaction Score
0.996

P08473

(UniProtKB/Swiss-Prot/P) Details

Neprilysin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.86 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Secretory granule membrane (GO:0030667) 0.79 Unknown: traceable author statement GO PubMed 
Secretory-pathway Synaptic vesicle (GO:0008021) 0.79 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Brush border (GO:0005903) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Dendrite (GO:0030425) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Neuron projection terminus (GO:0044306) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Axon (GO:0030424) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Unknown: non-traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: pTarget method LOCATE PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Integral to plasma membrane (GO:0005887) 1 Unknown: non-traceable author statement GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.86 Unknown: HDA GO PubMed 
Membrane Focal adhesion (GO:0005925) 1 Unknown: HDA GO PubMed 
Membrane Synapse (GO:0045202) 1 Predicted: inferred from sequence or structural similarity GO PubMed 

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed 

P20800

Interaction Score
0.993

P23276

(UniProtKB/Swiss-Prot/P) Details

Kell blood group glycoprotein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoskeleton (GO:0005856) 0.96 Experimental: experimental eSLDB PubMed 
Cytosol Cytoskeleton (GO:0005856) 0.96 Experimental: experimental Organelle PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.994 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.994 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.994 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.994 Predicted: pTarget method LOCATE PubMed 
Membrane Plasma membrane (GO:0005886) 0.994 Experimental: experimental Organelle PubMed 

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed 

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ComPPI is published in Nucleic Acids Research Database Issue 2015