P26022

Pentraxin-related protein PTX3    //   UniProt Profile 

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Species

 H. sapiens

Number of Interactions

 18 / 20

Average Interaction Score

 0.855

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.958 Experimental: inferred from direct assay GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

P26022

Interaction Score
0.995

O00602

(UniProtKB/Swiss-Prot/P) Details

Ficolin-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.86 Experimental: experimental eSLDB PubMed 
Secretory-pathway Secretory granule lumen (GO:0034774) 0.86 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.991 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.991 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular region (GO:0005576) 0.991 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.991 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Collagen (GO:0005581) 0.991 Unknown: inferred from electronic annotation GO PubMed 
Membrane Membrane (GO:0016020) 0.96 Experimental: experimental MatrixDB PubMed 
Membrane Extrinsic to external side of plasma membrane (GO:0031232) 0.96 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P26022

Interaction Score
0.99

P02747

(UniProtKB/Swiss-Prot/P) Details

Complement C1q subcomponent subunit C

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.8 Experimental: experimental eSLDB PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.3 Unknown: unspecified method The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.978 Unknown: non-traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.978 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular region (GO:0005576) 0.978 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.978 Unknown: HDA GO PubMed 
Extracellular Blood microparticle (GO:0072562) 0.978 Unknown: HDA GO PubMed 
Extracellular Collagen (GO:0005581) 0.978 Unknown: inferred from electronic annotation GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed 

P26022

Interaction Score
0.989

Q9Y6Z7

(UniProtKB/Swiss-Prot/P) Details

Collectin-10

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.79 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.96 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.96 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 0.8 Experimental: experimental Organelle PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.79 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.971 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.971 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.971 Experimental: inferred from direct assay GO PubMed 
Extracellular Collagen (GO:0005581) 0.971 Unknown: inferred from electronic annotation GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P26022

Interaction Score
0.989

P08603

(UniProtKB/Swiss-Prot/P) Details

Complement factor H

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.8 Experimental: experimental eSLDB PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.86 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.969 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.969 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular region (GO:0005576) 0.969 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.969 Unknown: traceable author statement GO PubMed 
Extracellular Blood microparticle (GO:0072562) 0.969 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.86 Unknown: HDA GO PubMed 

Interaction Source Database:

HPRD, IntAct

Interaction Source Publication:

PubMed 

P26022

Interaction Score
0.988

P02746

(UniProtKB/Swiss-Prot/P) Details

Complement C1q subcomponent subunit B

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.978 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.978 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular region (GO:0005576) 0.978 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Complement component C1 complex (GO:0005602) 0.978 Unknown: traceable author statement GO PubMed 
Extracellular Blood microparticle (GO:0072562) 0.978 Unknown: HDA GO PubMed 
Extracellular Collagen (GO:0005581) 0.978 Unknown: inferred from electronic annotation GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed 

P26022

Interaction Score
0.987

P98066

(UniProtKB/Swiss-Prot/P) Details

Tumor necrosis factor-inducible gene 6 protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.971 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.971 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.971 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular matrix (GO:0031012) 0.971 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P26022

Interaction Score
0.987

O75636

(UniProtKB/Swiss-Prot/P) Details

Ficolin-3

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.969 Unknown: non-traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.969 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular region (GO:0005576) 0.969 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Blood microparticle (GO:0072562) 0.969 Unknown: HDA GO PubMed 
Extracellular Collagen (GO:0005581) 0.969 Unknown: inferred from electronic annotation GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P26022

Interaction Score
0.987

Q15485

(UniProtKB/Swiss-Prot/P) Details

Ficolin-2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.969 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.969 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular region (GO:0005576) 0.969 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Blood microparticle (GO:0072562) 0.969 Unknown: HDA GO PubMed 
Extracellular Collagen (GO:0005581) 0.969 Unknown: inferred from electronic annotation GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.3 Unknown: HDA GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P26022

Interaction Score
0.986

P01023

(UniProtKB/Swiss-Prot/P) Details

Alpha-2-macroglobulin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.79 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.51 Unknown: traceable author statement GO PubMed 
Secretory-pathway Platelet alpha granule lumen (GO:0031093) 0.79 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.956 Unknown: non-traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.956 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular region (GO:0005576) 0.956 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Blood microparticle (GO:0072562) 0.956 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.51 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P26022

Interaction Score
0.984

Q8WUJ1

(UniProtKB/Swiss-Prot/P) Details

Neuferricin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.91 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Endomembrane system (GO:0012505) 0.94 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Nucleolus (GO:0005730) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nuclear membrane (GO:0031965) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Centrosome (GO:0005813) 0.94 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.86 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.94 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Membrane (GO:0016020) 0.94 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P26022

Interaction Score
0.981

P09038

(UniProtKB/Swiss-Prot/P) Details

Fibroblast growth factor 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.992 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.992 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nuclear body (GO:0016604) 0.992 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.987 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.987 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular region (GO:0005576) 0.987 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.987 Experimental: inferred from direct assay GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

HPRD, IntAct

Interaction Source Publication:

PubMed , PubMed 

P26022

Interaction Score
0.98

P02745

(UniProtKB/Swiss-Prot/P) Details

Complement C1q subcomponent subunit A

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.86 Experimental: experimental eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.3 Unknown: unspecified method The Human Protein Atlas PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.86 Unknown: unspecified method The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.897 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.897 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Complement component C1 complex (GO:0005602) 0.897 Unknown: traceable author statement GO PubMed 
Extracellular Collagen (GO:0005581) 0.897 Unknown: inferred from electronic annotation GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed 

P26022

Interaction Score
0.974

P27918

(UniProtKB/Swiss-Prot/P) Details

Properdin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.86 Experimental: experimental eSLDB PubMed 
Secretory-pathway Endoplasmic reticulum lumen (GO:0005788) 0.86 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.853 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.853 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.853 Unknown: traceable author statement GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P26022

Interaction Score
0.971

Q14624

(UniProtKB/Swiss-Prot/P) Details

Inter-alpha-trypsin inhibitor heavy chain H4

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.86 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.853 Unknown: non-traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.853 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Blood microparticle (GO:0072562) 0.853 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 0.86 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.86 Unknown: HDA GO PubMed 

Interaction Source Database:

MatrixDB

Interaction Source Publication:

PubMed 

P26022

Interaction Score
0.953

P48039

(UniProtKB/Swiss-Prot/P) Details

Melatonin receptor type 1A

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Experimental: experimental eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 1 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to plasma membrane (GO:0005887) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Receptor complex (GO:0043235) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

P26022

Interaction Score
0.64

Q6PF06

(UniProtKB/Swiss-Prot/P) Details

tRNA methyltransferase 10 homolog B

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.982 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.982 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytosol (GO:0005829) 0.982 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Plasma membrane (GO:0005886) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P26022

Interaction Score
0

Q9UK11

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein 223

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Mitochondrion Mitochondrion (GO:0005739) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.997 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.997 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.997 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 0.997 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.997 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P26022

Interaction Score
0

Q9NZL3

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein 224

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nuclear membrane (GO:0031965) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear membrane (GO:0031965) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Transcriptional repressor complex (GO:0017053) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

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ComPPI is published in Nucleic Acids Research Database Issue 2015