P31946

14-3-3 protein beta/alpha // UniProt Profile

Custom Settings: Use these controls to filter the data displayed on this page. The parameters apply to both the query protein and its interactors. Details

The (filtered) results are available for download, see the help for details. Download The Results

Species	H. sapiens
Number of Interactions	607 / 838
Average Interaction Score	0.933

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.902	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Transcriptional repressor complex (GO:0017053)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Melanosome (GO:0042470)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Human Proteinpedia	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.51	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.51	Unknown: HDA	GO	PubMed

First-Neighbour Network Visualization

Toggle Display

The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

P31946

Interaction Score

P37840

(UniProtKB/Swiss-Prot/P) Details

Alpha-synuclein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Neuronal cell body (GO:0043025)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Inclusion body (GO:0016234)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Ribosome (GO:0005840)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cell cortex (GO:0005938)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.832	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrial matrix (GO:0005759)	0.832	Unknown: inferred from electronic annotation	GO	PubMed
Mitochondrion	Mitochondrial intermembrane space (GO:0005758)	0.832	Unknown: inferred from electronic annotation	GO	PubMed
Mitochondrion	Mitochondrial respiratory chain complex I (GO:0005747)	0.832	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrial outer membrane (GO:0005741)	0.832	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.972	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.972	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear outer membrane (GO:0005640)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Rough endoplasmic reticulum (GO:0005791)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Lysosome (GO:0005764)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Platelet alpha granule membrane (GO:0031092)	0.931	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Synaptic vesicle membrane (GO:0030672)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Growth cone (GO:0030426)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Axon (GO:0030424)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.992	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.992	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.992	Experimental: inferred from direct assay	GO	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Terminal button (GO:0043195)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

P31946

Interaction Score

P00441

(UniProtKB/Swiss-Prot/P) Details

Superoxide dismutase [Cu-Zn]

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Myelin sheath (GO:0043209)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Neuronal cell body (GO:0043025)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.902	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial matrix (GO:0005759)	0.902	Unknown: non-traceable author statement	GO	PubMed
Mitochondrion	Mitochondrial intermembrane space (GO:0005758)	0.902	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Lysosome (GO:0005764)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Peroxisome (GO:0005777)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.86	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Dense core granule (GO:0031045)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendrite cytoplasm (GO:0032839)	0.999	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.994	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular space (GO:0005615)	0.994	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.994	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.994	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.999	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q5S007

(UniProtKB/Swiss-Prot/P) Details

Leucine-rich repeat serine/threonine-protein kinase 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Neuronal cell body (GO:0043025)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Perikaryon (GO:0043204)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Intracellular (GO:0005622)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Cytosol	Inclusion body (GO:0016234)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial matrix (GO:0005759)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Mitochondrion	Mitochondrial membrane (GO:0031966)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	External side of mitochondrial outer membrane (GO:0032473)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Mitochondrion	Mitochondrial outer membrane (GO:0005741)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Golgi-associated vesicle (GO:0005798)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Trans-Golgi network (GO:0005802)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Multivesicular body, internal vesicle (GO:0097487)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Amphisome (GO:0044753)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Lysosome (GO:0005764)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Synaptic vesicle membrane (GO:0030672)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Growth cone (GO:0030426)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Microvillus (GO:0005902)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Neuron projection (GO:0043005)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Dendrite (GO:0030425)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Dendrite cytoplasm (GO:0032839)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Axon (GO:0030424)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.86	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Terminal button (GO:0043195)	1	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

P08238

(UniProtKB/Swiss-Prot/P) Details

Heat shock protein HSP 90-beta

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Neuronal cell body (GO:0043025)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Inclusion body (GO:0016234)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.3	Unknown: HDA	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.994	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Signalosome (GO:0008180)	0.994	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.994	Unknown: traceable author statement	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.994	Experimental: inferred from mutant phenotype	GO	PubMed
Cytosol	Lysosomal membrane (GO:0005765)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Melanosome (GO:0042470)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Secretory granule lumen (GO:0034774)	0.51	Unknown: traceable author statement	GO	PubMed
Membrane	Dendritic growth cone (GO:0044294)	0.997	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Brush border membrane (GO:0031526)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Axonal growth cone (GO:0044295)	0.997	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.96	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.96	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.997	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.997	Experimental: experimental	MatrixDB	PubMed
Membrane	Apical plasma membrane (GO:0016324)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Basolateral plasma membrane (GO:0016323)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

P10636

(UniProtKB/Swiss-Prot/P) Details

Microtubule-associated protein tau

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cell body (GO:0044297)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Neuronal cell body (GO:0043025)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Cytosol	Intracellular (GO:0005622)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Cytosol (GO:0005829)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
N/A	Neurofibrillary tangle (GO:0097418)	0.8	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.3	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nuclear periphery (GO:0034399)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule associated complex (GO:0005875)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Tubulin complex (GO:0045298)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule (GO:0005874)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Glial cell projection (GO:0097386)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Growth cone (GO:0030426)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Dendrite (GO:0030425)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Dendritic spine (GO:0043197)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Axon (GO:0030424)	1	Unknown: non-traceable author statement	GO	PubMed
Membrane	Main axon (GO:0044304)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Axolemma (GO:0030673)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Unknown: non-traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Membrane	Membrane raft (GO:0045121)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

HPRD, BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q9H0H5

(UniProtKB/Swiss-Prot/P) Details

Rac GTPase-activating protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Midbody (GO:0030496)	0.972	Experimental: inferred from direct assay	GO	PubMed
Membrane	Flemming body (GO:0090543)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cleavage furrow (GO:0032154)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.86	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Acrosomal vesicle (GO:0001669)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Centralspindlin complex (GO:0097149)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Mitotic spindle (GO:0072686)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Cytosol	Spindle midzone (GO:0051233)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule (GO:0005874)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Extrinsic to internal side of plasma membrane (GO:0031234)	0.972	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Vesicle (GO:0031982)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

P0DMV8

(UniProtKB/Swiss-Prot/P) Details

Heat shock 70 kDa protein 1A

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Ubiquitin ligase complex (GO:0000151)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Inclusion body (GO:0016234)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Aggresome (GO:0016235)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.86	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.86	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Signalosome (GO:0008180)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.86	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.86	Experimental: experimental	Organelle	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centriole (GO:0005814)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.51	Unknown: traceable author statement	GO	PubMed
Extracellular	Blood microparticle (GO:0072562)	0.51	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.86	Experimental: experimental	MatrixDB	PubMed
Cytosol	Vesicle (GO:0031982)	1	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.86	Unknown: HDA	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

P0DMV9

(UniProtKB/Swiss-Prot/P) Details

Heat shock 70 kDa protein 1B

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Ubiquitin ligase complex (GO:0000151)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Inclusion body (GO:0016234)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Aggresome (GO:0016235)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.86	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.86	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.86	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.86	Experimental: experimental	Organelle	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centriole (GO:0005814)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.51	Unknown: traceable author statement	GO	PubMed
Extracellular	Blood microparticle (GO:0072562)	0.51	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.86	Experimental: experimental	MatrixDB	PubMed
Cytosol	Vesicle (GO:0031982)	1	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.86	Unknown: HDA	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q14247

(UniProtKB/Swiss-Prot/P) Details

Src substrate cortactin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Coated pit (GO:0005905)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cell cortex (GO:0005938)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.96	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Mitotic spindle midzone (GO:1990023)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Podosome (GO:0002102)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cortical cytoskeleton (GO:0030863)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Actin filament (GO:0005884)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Growth cone (GO:0030426)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Ruffle (GO:0001726)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Lamellipodium (GO:0030027)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Dendritic spine (GO:0043197)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Voltage-gated potassium channel complex (GO:0008076)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

O75122

(UniProtKB/Swiss-Prot/P) Details

CLIP-associating protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell leading edge (GO:0031252)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Unknown: non-traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cell cortex (GO:0005938)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Basal cortex (GO:0045180)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.987	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.987	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.992	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Trans-Golgi network (GO:0005802)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Mitotic spindle (GO:0072686)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Cytosol	Kinetochore microtubule (GO:0005828)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Microtubule (GO:0005874)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasmic microtubule (GO:0005881)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Condensed chromosome kinetochore (GO:0000777)	0.987	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Kinetochore (GO:0000776)	0.987	Experimental: inferred from mutant phenotype	GO	PubMed
Membrane	Ruffle membrane (GO:0032587)	0.999	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Membrane (GO:0016020)	0.999	Unknown: HDA	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Experimental: inferred from direct assay	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.999	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

O00429

(UniProtKB/Swiss-Prot/P) Details

Dynamin-1-like protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Coated pit (GO:0005905)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.988	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.988	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrial outer membrane (GO:0005741)	0.988	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.94	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.997	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.997	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.997	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.997	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Peroxisome (GO:0005777)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Synaptic vesicle membrane (GO:0030672)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Microtubule (GO:0005874)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.51	Unknown: HDA	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.51	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

P49815

(UniProtKB/Swiss-Prot/P) Details

Tuberin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	TSC1-TSC2 complex (GO:0033596)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Lysosome (GO:0005764)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Postsynaptic density (GO:0014069)	0.998	Experimental: inferred from experiment	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.998	Experimental: inferred from direct assay	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Experimental: experimental	Organelle	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

Q08495

(UniProtKB/Swiss-Prot/P) Details

Dematin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endomembrane system (GO:0012505)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Platelet dense tubular network membrane (GO:0031095)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.982	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.982	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	0.982	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Spectrin-associated cytoskeleton (GO:0014731)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cortical cytoskeleton (GO:0030863)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Actin filament (GO:0005884)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell projection membrane (GO:0031253)	0.958	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Postsynaptic density (GO:0014069)	0.958	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.958	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q7Z460

(UniProtKB/Swiss-Prot/P) Details

CLIP-associating protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cell cortex (GO:0005938)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Basal cortex (GO:0045180)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Spindle microtubule (GO:0005876)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Kinetochore microtubule (GO:0005828)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Centrosomal corona (GO:0031592)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cortical microtubule cytoskeleton (GO:0030981)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasmic microtubule (GO:0005881)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule plus end (GO:0035371)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Condensed chromosome kinetochore (GO:0000777)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Kinetochore (GO:0000776)	0.86	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Membrane (GO:0016020)	0.86	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.86	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q92574

(UniProtKB/Swiss-Prot/P) Details

Hamartin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Lipid particle (GO:0005811)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	TSC1-TSC2 complex (GO:0033596)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cell cortex (GO:0005938)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.94	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Actin filament (GO:0005884)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Growth cone (GO:0030426)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Lamellipodium (GO:0030027)	0.997	Experimental: inferred from direct assay	GO	PubMed
Membrane	Postsynaptic density (GO:0014069)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.997	Experimental: experimental	eSLDB	PubMed
Membrane	Membrane (GO:0016020)	0.997	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.997	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

Q92974

(UniProtKB/Swiss-Prot/P) Details

Rho guanine nucleotide exchange factor 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Neuronal cell body (GO:0043025)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.94	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Spindle (GO:0005819)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Podosome (GO:0002102)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Microtubule (GO:0005874)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Ruffle membrane (GO:0032587)	0.931	Experimental: inferred from direct assay	GO	PubMed
Membrane	Dendritic shaft (GO:0043198)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Cytosol	Vesicle (GO:0031982)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.931	Unknown: HDA	GO	PubMed
Membrane	Tight junction (GO:0005923)	0.931	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

P55072

(UniProtKB/Swiss-Prot/P) Details

Transitional endoplasmic reticulum ATPase

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Myelin sheath (GO:0043209)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Lipid particle (GO:0005811)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasmic stress granule (GO:0010494)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Proteasome complex (GO:0000502)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.994	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.994	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Cdc48p-Npl4p-Ufd1p AAA ATPase complex (GO:0034098)	0.994	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Secretory granule lumen (GO:0034774)	0.994	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Azurophil granule lumen (GO:0035578)	0.994	Unknown: traceable author statement	GO	PubMed
Nucleus	Site of double-strand break (GO:0035861)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.3	Unknown: traceable author statement	GO	PubMed
Membrane	Membrane (GO:0016020)	0.86	Experimental: experimental	MatrixDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q99497

(UniProtKB/Swiss-Prot/P) Details

Protein/nucleic acid deglycase DJ-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cell body (GO:0044297)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: experimental	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Predicted: pTarget method	LOCATE	PubMed
Mitochondrion	Mitochondrial matrix (GO:0005759)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Mitochondrion	Mitochondrial intermembrane space (GO:0005758)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Mitochondrion	Mitochondrial respiratory chain complex I (GO:0005747)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	PML body (GO:0016605)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Chromatin (GO:0000785)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Axon (GO:0030424)	0.897	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane raft (GO:0045121)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Cell-cell adherens junction (GO:0005913)	0.897	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q96Q89

(UniProtKB/Swiss-Prot/P) Details

Kinesin-like protein KIF20B

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Contractile ring (GO:0070938)	0.958	Experimental: inferred from direct assay	GO	PubMed
Membrane	Midbody (GO:0030496)	0.958	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Spindle midzone (GO:0051233)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Mitotic spindle midzone (GO:1990023)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Mitotic spindle pole (GO:0097431)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Kinesin complex (GO:0005871)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule (GO:0005874)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Growth cone (GO:0030426)	0.958	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q99570

(UniProtKB/Swiss-Prot/P) Details

Phosphoinositide 3-kinase regulatory subunit 4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Phosphatidylinositol 3-kinase complex I (GO:0034271)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Phosphatidylinositol 3-kinase complex II (GO:0034272)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Phosphatidylinositol 3-kinase complex, class III (GO:0035032)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nuclear pore (GO:0005643)	0.91	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Secretory-pathway	Late endosome (GO:0005770)	0.86	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Autophagic vacuole (GO:0005776)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Phagocytic vesicle membrane (GO:0030670)	0.86	Unknown: traceable author statement	GO	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Axoneme (GO:0005930)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed
Cytosol	Nucleus-vacuole junction (GO:0071561)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

O14745

(UniProtKB/Swiss-Prot/P) Details

Na(+)/H(+) exchange regulatory cofactor NHE-RF1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endomembrane system (GO:0012505)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Stereocilium bundle tip (GO:0032426)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Cell periphery (GO:0071944)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Ruffle (GO:0001726)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Microvillus (GO:0005902)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Microvillus membrane (GO:0031528)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Brush border membrane (GO:0031526)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Filopodium (GO:0030175)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Sperm midpiece (GO:0097225)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Membrane raft (GO:0045121)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Apical plasma membrane (GO:0016324)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Vesicle (GO:0031982)	1	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

P05067

(UniProtKB/Swiss-Prot/P) Details

Amyloid-beta A4 protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Cell surface (GO:0009986)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Coated pit (GO:0005905)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Apical part of cell (GO:0045177)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: experimental	eSLDB	PubMed
Nucleus	Nuclear envelope lumen (GO:0005641)	0.96	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Rough endoplasmic reticulum (GO:0005791)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Smooth endoplasmic reticulum (GO:0005790)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum lumen (GO:0005788)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi lumen (GO:0005796)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Trans-Golgi network membrane (GO:0032588)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	1	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endosome (GO:0005768)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endosome lumen (GO:0031904)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Lysosome (GO:0005764)	1	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Platelet alpha granule lumen (GO:0031093)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	ER to Golgi transport vesicle (GO:0030134)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Spindle midzone (GO:0051233)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Astrocyte projection (GO:0097449)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendritic shaft (GO:0043198)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Dendritic spine (GO:0043197)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Axon (GO:0030424)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Main axon (GO:0044304)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Ciliary rootlet (GO:0035253)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.98	Experimental: experimental	eSLDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.98	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.98	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.98	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Membrane raft (GO:0045121)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: pTarget method	LOCATE	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Receptor complex (GO:0043235)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Vesicle (GO:0031982)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Cell-cell junction (GO:0005911)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Synapse (GO:0045202)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Neuromuscular junction (GO:0031594)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Presynaptic active zone (GO:0048786)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

P26196

(UniProtKB/Swiss-Prot/P) Details

Probable ATP-dependent RNA helicase DDX6

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	RNA-induced silencing complex (GO:0016442)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasmic stress granule (GO:0010494)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Chromatoid body (GO:0033391)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasmic mRNA processing body (GO:0000932)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Unknown: inferred from electronic annotation	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.987	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.987	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	0.987	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Heterochromatin (GO:0000792)	0.987	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Outer dense fiber (GO:0001520)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Sperm annulus (GO:0097227)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.657	Unknown: HDA	GO	PubMed
Membrane	Cell-cell adherens junction (GO:0005913)	0.657	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q14145

(UniProtKB/Swiss-Prot/P) Details

Kelch-like ECH-associated protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cul3-RING ubiquitin ligase complex (GO:0031463)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Midbody (GO:0030496)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.988	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Actin filament (GO:0005884)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q9UHB6

(UniProtKB/Swiss-Prot/P) Details

LIM domain and actin-binding protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cleavage furrow (GO:0032154)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Stress fiber (GO:0001725)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Brush border membrane (GO:0031526)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q96Q42

(UniProtKB/Swiss-Prot/P) Details

Alsin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Neuronal cell body (GO:0043025)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.8	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intermediate filament cytoskeleton (GO:0045111)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Growth cone (GO:0030426)	0.998	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Ruffle (GO:0001726)	0.998	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Lamellipodium (GO:0030027)	0.998	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Dendrite (GO:0030425)	0.998	Experimental: inferred from direct assay	GO	PubMed
Membrane	Dendritic spine (GO:0043197)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic density (GO:0014069)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Vesicle (GO:0031982)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q9UPN4

(UniProtKB/Swiss-Prot/P) Details

Centrosomal protein of 131 kDa

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Secretory-pathway	Acrosomal vesicle (GO:0001669)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centriolar satellite (GO:0034451)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Ciliary transition zone (GO:0035869)	0.8	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Intercellular bridge (GO:0045171)	0.96	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Intercellular bridge (GO:0045171)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

P16591

(UniProtKB/Swiss-Prot/P) Details

Tyrosine-protein kinase Fer

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cell cortex (GO:0005938)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear chromatin (GO:0000790)	0.998	Experimental: inferred from direct assay	GO	PubMed
Membrane	Lamellipodium (GO:0030027)	0.992	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Extrinsic to internal side of plasma membrane (GO:0031234)	0.992	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.992	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q15051

(UniProtKB/Swiss-Prot/P) Details

IQ calmodulin-binding motif-containing protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.94	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Mitotic spindle (GO:0072686)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centriole (GO:0005814)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Photoreceptor connecting cilium (GO:0032391)	0.86	Experimental: inferred from direct assay	GO	PubMed
Membrane	Photoreceptor outer segment (GO:0001750)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Intercellular bridge (GO:0045171)	0.96	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Intercellular bridge (GO:0045171)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q9NQC7

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin carboxyl-terminal hydrolase CYLD

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Midbody (GO:0030496)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Spindle (GO:0005819)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cilium basal body (GO:0036064)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasmic microtubule (GO:0005881)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Extrinsic to internal side of plasma membrane (GO:0031234)	0.96	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

P27348

(UniProtKB/Swiss-Prot/P) Details

14-3-3 protein theta

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Human Proteinpedia	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.657	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.657	Unknown: HDA	GO	PubMed
Membrane	Synapse (GO:0045202)	0.657	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, DIP, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

P04792

(UniProtKB/Swiss-Prot/P) Details

Heat shock protein beta-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Proteasome complex (GO:0000502)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Z disc (GO:0030018)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Spindle (GO:0005819)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular space (GO:0005615)	0.86	Unknown: HDA	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.86	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.98	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.98	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.98	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.98	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

P26651

(UniProtKB/Swiss-Prot/P) Details

mRNA decay activator protein ZFP36

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	RISC-loading complex (GO:0070578)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasmic stress granule (GO:0010494)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasmic mRNA processing body (GO:0000932)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Exosome (RNase complex) (GO:0000178)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	CCR4-NOT complex (GO:0030014)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Intermediate filament cytoskeleton (GO:0045111)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

HPRD, BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

P08670

(UniProtKB/Swiss-Prot/P) Details

Vimentin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell leading edge (GO:0031252)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Polysome (GO:0005844)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear matrix (GO:0016363)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Peroxisome (GO:0005777)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Phagocytic vesicle (GO:0045335)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Intermediate filament cytoskeleton (GO:0045111)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Intermediate filament (GO:0005882)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Neuron projection (GO:0043005)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.931	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.931	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

O43379

(UniProtKB/Swiss-Prot/P) Details

WD repeat-containing protein 62

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	U5 snRNP (GO:0005682)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.982	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Precatalytic spliceosome (GO:0071011)	0.982	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Catalytic step 2 spliceosome (GO:0071013)	0.982	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Spindle pole (GO:0000922)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centriole (GO:0005814)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q15029

(UniProtKB/Swiss-Prot/P) Details

116 kDa U5 small nuclear ribonucleoprotein component

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Ribonucleoprotein complex (GO:0030529)	1	Experimental: experimental	Organelle	PubMed
Cytosol	U4/U6 x U5 tri-snRNP complex (GO:0046540)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Cajal body (GO:0015030)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Spliceosomal complex (GO:0005681)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	U2-type catalytic step 2 spliceosome (GO:0071007)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Catalytic step 2 spliceosome (GO:0071013)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.96	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.96	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

P42858

(UniProtKB/Swiss-Prot/P) Details

Huntingtin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Inclusion body (GO:0016234)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Late endosome (GO:0005770)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Autophagic vacuole (GO:0005776)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle membrane (GO:0030659)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centriole (GO:0005814)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Dendrite (GO:0030425)	0.988	Experimental: inferred from direct assay	GO	PubMed
Membrane	Axon (GO:0030424)	0.988	Experimental: inferred from direct assay	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.988	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q9P0K7

(UniProtKB/Swiss-Prot/P) Details

Ankycorbin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cell cortex (GO:0005938)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Fibrillar center (GO:0001650)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Plasma membrane (GO:0005886)	0.86	Experimental: experimental	Human Proteinpedia	PubMed
Membrane	Cell junction (GO:0030054)	0.86	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

Q9NZJ0

(UniProtKB/Swiss-Prot/P) Details

Denticleless protein homolog

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	CUL4 RING ubiquitin ligase complex (GO:0080008)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Cytosol	Cul4A-RING ubiquitin ligase complex (GO:0031464)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cul4B-RING ubiquitin ligase complex (GO:0031465)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear membrane (GO:0031965)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Chromosome (GO:0005694)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q02241

(UniProtKB/Swiss-Prot/P) Details

Kinesin-like protein KIF23

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Midbody (GO:0030496)	0.902	Experimental: inferred from direct assay	GO	PubMed
Membrane	Flemming body (GO:0090543)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Spindle (GO:0005819)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centralspindlin complex (GO:0097149)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Mitotic spindle (GO:0072686)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Kinesin complex (GO:0005871)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule (GO:0005874)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Intercellular bridge (GO:0045171)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.902	Unknown: HDA	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

P62258

(UniProtKB/Swiss-Prot/P) Details

14-3-3 protein epsilon

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: unspecified method	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Melanosome (GO:0042470)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Kinesin complex (GO:0005871)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.902	Unknown: HDA	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.902	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.902	Unknown: HDA	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, DIP, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

Q96L34

(UniProtKB/Swiss-Prot/P) Details

MAP/microtubule affinity-regulating kinase 4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Midbody (GO:0030496)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cilium basal body (GO:0036064)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Gamma-tubulin complex (GO:0000930)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Neuron projection (GO:0043005)	0.992	Experimental: inferred from direct assay	GO	PubMed
Membrane	Dendrite (GO:0030425)	0.992	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

P31946

Interaction Score

P62979

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin-40S ribosomal protein S27a

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Unknown: HDA	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Small ribosomal subunit (GO:0015935)	1	Unknown: HDA	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytosolic small ribosomal subunit (GO:0022627)	1	Unknown: HDA	GO	PubMed
Mitochondrion	Mitochondrial outer membrane (GO:0005741)	0.3	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.994	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.994	Unknown: HDA	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.994	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	0.994	Unknown: HDA	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	0.994	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.994	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.931	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.931	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endosome membrane (GO:0010008)	0.931	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endocytic vesicle membrane (GO:0030666)	0.931	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Human Proteinpedia	PubMed
Extracellular	Extracellular region (GO:0005576)	0.902	Experimental: experimental	MatrixDB	PubMed
Extracellular	Host cell (GO:0043657)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular space (GO:0005615)	0.902	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.902	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.902	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.902	Unknown: traceable author statement	GO	PubMed
Cytosol	Vesicle (GO:0031982)	1	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q9BX66

(UniProtKB/Swiss-Prot/P) Details

Sorbin and SH3 domain-containing protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.987	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.987	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.987	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nuclear matrix (GO:0016363)	0.987	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Stress fiber (GO:0001725)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane raft (GO:0045121)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Human Proteinpedia	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Insulin receptor complex (GO:0005899)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell-substrate adherens junction (GO:0005924)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Cell-cell adherens junction (GO:0005913)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Zonula adherens (GO:0005915)	1	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

P07437

(UniProtKB/Swiss-Prot/P) Details

Tubulin beta chain

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cell body (GO:0044297)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	0.972	Unknown: HDA	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.972	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nuclear envelope lumen (GO:0005641)	0.972	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Azurophil granule lumen (GO:0035578)	0.3	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Microtubule (GO:0005874)	1	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.86	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.86	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane raft (GO:0045121)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

P33176

(UniProtKB/Swiss-Prot/P) Details

Kinesin-1 heavy chain

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Phagocytic vesicle (GO:0045335)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Kinesin complex (GO:0005871)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Microtubule (GO:0005874)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Axonal growth cone (GO:0044295)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Ciliary rootlet (GO:0035253)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.657	Unknown: HDA	GO	PubMed
Cytosol	Vesicle (GO:0031982)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

Q9Y2H1

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein kinase 38-like

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q9H8V3

(UniProtKB/Swiss-Prot/P) Details

Protein ECT2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Midbody (GO:0030496)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cleavage furrow (GO:0032154)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Centralspindlin complex (GO:0097149)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Mitotic spindle (GO:0072686)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell-cell junction (GO:0005911)	0.992	Experimental: inferred from direct assay	GO	PubMed
Membrane	Tight junction (GO:0005923)	0.992	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q9HC77

(UniProtKB/Swiss-Prot/P) Details

Centromere protein J

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.988	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cilium basal body (GO:0036064)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Centriole (GO:0005814)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Gamma-tubulin small complex (GO:0008275)	1	Unknown: non-traceable author statement	GO	PubMed
Cytosol	Microtubule (GO:0005874)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

P36405

(UniProtKB/Swiss-Prot/P) Details

ADP-ribosylation factor-like protein 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Midbody (GO:0030496)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.958	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.958	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.958	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Spindle microtubule (GO:0005876)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytoplasmic microtubule (GO:0005881)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cilium (GO:0005929)	0.992	Experimental: inferred from direct assay	GO	PubMed
Membrane	Photoreceptor connecting cilium (GO:0032391)	0.992	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

DIP, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q13813

(UniProtKB/Swiss-Prot/P) Details

Spectrin alpha chain, non-erythrocytic 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Spectrin (GO:0008091)	1	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.86	Unknown: traceable author statement	GO	PubMed
Membrane	Membrane (GO:0016020)	0.86	Experimental: experimental	MatrixDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

P08F94

(UniProtKB/Swiss-Prot/P) Details

Fibrocystin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Mitotic spindle (GO:0072686)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cilium basal body (GO:0036064)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Chromosome, centromeric region (GO:0000775)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Cilium (GO:0005929)	0.999	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.999	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.999	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Anchored to external side of plasma membrane (GO:0031362)	0.999	Unknown: traceable author statement	GO	PubMed
Membrane	Apical plasma membrane (GO:0016324)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q05655

(UniProtKB/Swiss-Prot/P) Details

Protein kinase C delta type

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.902	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear matrix (GO:0016363)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.902	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.994	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.994	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.994	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Azurophil granule lumen (GO:0035578)	0.994	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.972	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.972	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Cell-cell junction (GO:0005911)	0.972	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q9H0R8

(UniProtKB/Swiss-Prot/P) Details

Gamma-aminobutyric acid receptor-associated protein-like 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cell body (GO:0044297)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Intracellular (GO:0005622)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: inferred from genetic interaction	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.897	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Autophagic vacuole (GO:0005776)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Autophagic vacuole membrane (GO:0000421)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle membrane (GO:0030659)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Microtubule (GO:0005874)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendrite cytoplasm (GO:0032839)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendrite membrane (GO:0032590)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

P00519

(UniProtKB/Swiss-Prot/P) Details

Tyrosine-protein kinase ABL1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell leading edge (GO:0031252)	0.937	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Neuronal cell body (GO:0043025)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.3	Unknown: non-traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear membrane (GO:0031965)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Predicted: inferred from physical interaction	GO	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Dendrite (GO:0030425)	0.937	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Extrinsic to internal side of plasma membrane (GO:0031234)	0.937	Predicted: inferred from biological aspect of ancestor	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

Q9Y4P1

(UniProtKB/Swiss-Prot/P) Details

Cysteine protease ATG4B

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Lysosome (GO:0005764)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

P52907

(UniProtKB/Swiss-Prot/P) Details

F-actin-capping protein subunit alpha-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	WASH complex (GO:0071203)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	F-actin capping protein complex (GO:0008290)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.3	Unknown: traceable author statement	GO	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	MatrixDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

P11413

(UniProtKB/Swiss-Prot/P) Details

Glucose-6-phosphate 1-dehydrogenase

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.7	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.86	Unknown: HDA	GO	PubMed
Membrane	Internal side of plasma membrane (GO:0009898)	0.86	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

P53041

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein phosphatase 5

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Perikaryon (GO:0043204)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.3	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

P15056

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein kinase B-raf

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular (GO:0005622)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.79	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.79	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.7	Predicted: inferred from biological aspect of ancestor	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

P05783

(UniProtKB/Swiss-Prot/P) Details

Keratin, type I cytoskeletal 18

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Intermediate filament (GO:0005882)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Keratin filament (GO:0045095)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centriolar satellite (GO:0034451)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell periphery (GO:0071944)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Cell-cell adherens junction (GO:0005913)	0.51	Unknown: HDA	GO	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q9P287

(UniProtKB/Swiss-Prot/P) Details

BRCA2 and CDKN1A-interacting protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cyclin-dependent protein kinase holoenzyme complex (GO:0000307)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear cyclin-dependent protein kinase holoenzyme complex (GO:0019908)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Mitotic spindle pole (GO:0097431)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centriole (GO:0005814)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

P62987

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin-60S ribosomal protein L40

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Ribosome (GO:0005840)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial outer membrane (GO:0005741)	0.3	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.997	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.997	Unknown: HDA	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.997	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.997	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.997	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.986	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.986	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.986	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endosome membrane (GO:0010008)	0.986	Unknown: traceable author statement	GO	PubMed
Cytosol	Lysosomal membrane (GO:0005765)	1	Unknown: HDA	GO	PubMed
Secretory-pathway	Endocytic vesicle membrane (GO:0030666)	0.986	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.902	Experimental: experimental	MatrixDB	PubMed
Extracellular	Host cell (GO:0043657)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular space (GO:0005615)	0.902	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.992	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.992	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Vesicle (GO:0031982)	1	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

P31946

Interaction Score

O60333

(UniProtKB/Swiss-Prot/P) Details

Kinesin-like protein KIF1B

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endomembrane system (GO:0012505)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: unspecified method	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.937	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.937	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Fibrillar center (GO:0001650)	0.937	Unknown: unspecified method	The Human Protein Atlas	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.91	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle membrane (GO:0030659)	0.91	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Microtubule associated complex (GO:0005875)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Kinesin complex (GO:0005871)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Microtubule (GO:0005874)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Neuron projection (GO:0043005)	0.7	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q9H0B6

(UniProtKB/Swiss-Prot/P) Details

Kinesin light chain 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.992	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Kinesin complex (GO:0005871)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Kinesin I complex (GO:0016938)	1	Unknown: non-traceable author statement	GO	PubMed
Cytosol	Microtubule (GO:0005874)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.972	Unknown: HDA	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.972	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.972	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q7KZI7

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein kinase MARK2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.3	Unknown: non-traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.996	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Microtubule bundle (GO:0097427)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Actin filament (GO:0005884)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Dendrite (GO:0030425)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Lateral plasma membrane (GO:0016328)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

Q5SW79

(UniProtKB/Swiss-Prot/P) Details

Centrosomal protein of 170 kDa

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Spindle (GO:0005819)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Centriole (GO:0005814)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule (GO:0005874)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

P11021

(UniProtKB/Swiss-Prot/P) Details

Endoplasmic reticulum chaperone BiP

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Midbody (GO:0030496)	0.966	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell surface (GO:0009986)	0.966	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Myelin sheath (GO:0043209)	0.966	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Endomembrane system (GO:0012505)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: inferred from mutant phenotype	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: experimental	Organelle	PubMed
Nucleus	Signalosome (GO:0008180)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Smooth endoplasmic reticulum (GO:0005790)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum chaperone complex (GO:0034663)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum lumen (GO:0005788)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Integral to endoplasmic reticulum membrane (GO:0030176)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Integral to endoplasmic reticulum membrane (GO:0030176)	1	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Endoplasmic reticulum-Golgi intermediate compartment (GO:0005793)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Melanosome (GO:0042470)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.96	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.96	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.966	Unknown: HDA	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.966	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.966	Unknown: HDA	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

P68402

(UniProtKB/Swiss-Prot/P) Details

Platelet-activating factor acetylhydrolase IB subunit beta

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleolus (GO:0005730)	0.992	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Fibrillar center (GO:0001650)	0.992	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Secretory granule lumen (GO:0034774)	0.3	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.3	Unknown: traceable author statement	GO	PubMed
Membrane	Membrane (GO:0016020)	0.992	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.992	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

P12931

(UniProtKB/Swiss-Prot/P) Details

Proto-oncogene tyrosine-protein kinase Src

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Unknown: inferred from electronic annotation	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.96	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Late endosome (GO:0005770)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Lysosome (GO:0005764)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Podosome (GO:0002102)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Actin filament (GO:0005884)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Ruffle membrane (GO:0032587)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Neuron projection (GO:0043005)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic density (GO:0014069)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Extrinsic to internal side of plasma membrane (GO:0031234)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Caveola (GO:0005901)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q6Y7W6

(UniProtKB/Swiss-Prot/P) Details

GRB10-interacting GYF protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Perikaryon (GO:0043204)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytoplasmic stress granule (GO:0010494)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.94	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.992	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.992	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.992	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.51	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.51	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q9UQB8

(UniProtKB/Swiss-Prot/P) Details

Brain-specific angiogenesis inhibitor 1-associated protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Neuronal cell body (GO:0043025)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Rough endoplasmic reticulum (GO:0005791)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Secretory granule (GO:0030141)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Microtubule (GO:0005874)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Ruffle (GO:0001726)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Filopodium (GO:0030175)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendritic shaft (GO:0043198)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Neuron projection terminus (GO:0044306)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Cell-cell adherens junction (GO:0005913)	1	Unknown: HDA	GO	PubMed
Membrane	Excitatory synapse (GO:0060076)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Synaptic membrane (GO:0097060)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q05513

(UniProtKB/Swiss-Prot/P) Details

Protein kinase C zeta type

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell leading edge (GO:0031252)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Myelin sheath abaxonal region (GO:0035748)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Apical cortex (GO:0045179)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nuclear matrix (GO:0016363)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nuclear envelope (GO:0005635)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.86	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Stress fiber (GO:0001725)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic density (GO:0014069)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Axon hillock (GO:0043203)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Membrane raft (GO:0045121)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Apical plasma membrane (GO:0016324)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Vesicle (GO:0031982)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Cell-cell junction (GO:0005911)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Tight junction (GO:0005923)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

Q07812

(UniProtKB/Swiss-Prot/P) Details

Apoptosis regulator BAX

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Mitochondrion	Bcl-2 family protein complex (GO:0097136)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	BAX complex (GO:0097144)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Pore complex (GO:0046930)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial permeability transition pore complex (GO:0005757)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial outer membrane (GO:0005741)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear envelope (GO:0005635)	0.988	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.96	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell periphery (GO:0071944)	0.972	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.972	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.972	Experimental: experimental	eSLDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

P30153

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Protein phosphatase type 2A complex (GO:0000159)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.86	Unknown: non-traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.86	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	0.972	Unknown: non-traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.972	Experimental: experimental	Organelle	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Unknown: non-traceable author statement	GO	PubMed
Nucleus	Chromosome, centromeric region (GO:0000775)	0.972	Experimental: inferred from direct assay	GO	PubMed
Membrane	Dendrite (GO:0030425)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.657	Unknown: non-traceable author statement	GO	PubMed
Membrane	Lateral plasma membrane (GO:0016328)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q96N96

(UniProtKB/Swiss-Prot/P) Details

Spermatogenesis-associated protein 13

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Ruffle membrane (GO:0032587)	0.992	Experimental: inferred from direct assay	GO	PubMed
Membrane	Lamellipodium (GO:0030027)	0.992	Experimental: inferred from direct assay	GO	PubMed
Membrane	Filopodium (GO:0030175)	0.992	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q9H267

(UniProtKB/Swiss-Prot/P) Details

Vacuolar protein sorting-associated protein 33B

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Recycling endosome (GO:0055037)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Late endosome membrane (GO:0031902)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Early endosome membrane (GO:0031901)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Late endosome (GO:0005770)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	HOPS complex (GO:0030897)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Lysosome (GO:0005764)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Lysosomal membrane (GO:0005765)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Platelet alpha granule (GO:0031091)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Clathrin-coated vesicle (GO:0030136)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Clathrin complex (GO:0071439)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	AP-3 adaptor complex (GO:0030123)	0.96	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q07866

(UniProtKB/Swiss-Prot/P) Details

Kinesin light chain 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Neuronal cell body (GO:0043025)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: unspecified method	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.3	Unknown: unspecified method	The Human Protein Atlas	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Kinesin complex (GO:0005871)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Microtubule (GO:0005874)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Growth cone (GO:0030426)	0.853	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.853	Unknown: HDA	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.853	Unknown: unspecified method	The Human Protein Atlas	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

Q9UKB1

(UniProtKB/Swiss-Prot/P) Details

F-box/WD repeat-containing protein 11

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Ubiquitin ligase complex (GO:0000151)	1	Unknown: non-traceable author statement	GO	PubMed
Cytosol	Ubiquitin ligase complex (GO:0000151)	1	Experimental: experimental	Organelle	PubMed
Cytosol	SCF ubiquitin ligase complex (GO:0019005)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

P36507

(UniProtKB/Swiss-Prot/P) Details

Dual specificity mitogen-activated protein kinase kinase 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.3	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.3	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.931	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.931	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	0.931	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Late endosome (GO:0005770)	0.931	Unknown: traceable author statement	GO	PubMed
Cytosol	Peroxisomal membrane (GO:0005778)	1	Unknown: HDA	GO	PubMed
Cytosol	Microtubule (GO:0005874)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Unknown: non-traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.994	Experimental: experimental	MatrixDB	PubMed
Membrane	Internal side of plasma membrane (GO:0009898)	0.994	Experimental: inferred from direct assay	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.994	Unknown: traceable author statement	GO	PubMed
Membrane	Cell-cell junction (GO:0005911)	0.994	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

Q13618

(UniProtKB/Swiss-Prot/P) Details

Cullin-3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cul3-RING ubiquitin ligase complex (GO:0031463)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.937	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.937	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.937	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.86	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Polar microtubule (GO:0005827)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Sperm flagellum (GO:0036126)	0.86	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.86	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q14999

(UniProtKB/Swiss-Prot/P) Details

Cullin-7

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cul7-RING ubiquitin ligase complex (GO:0031467)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Anaphase-promoting complex (GO:0005680)	0.3	Unknown: non-traceable author statement	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q15208

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein kinase 38

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.8	Experimental: experimental	Human Proteinpedia	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q13283

(UniProtKB/Swiss-Prot/P) Details

Ras GTPase-activating protein-binding protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Perikaryon (GO:0043204)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasmic stress granule (GO:0010494)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.86	Experimental: experimental	eSLDB	PubMed
Cytosol	Vesicle (GO:0031982)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Focal adhesion (GO:0005925)	0.86	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

O14964

(UniProtKB/Swiss-Prot/P) Details

Hepatocyte growth factor-regulated tyrosine kinase substrate

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endosome (GO:0005768)	1	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endosome (GO:0005768)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Early endosome (GO:0005769)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Early endosome membrane (GO:0031901)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Multivesicular body membrane (GO:0032585)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	ESCRT-0 complex (GO:0033565)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Lysosome (GO:0005764)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Lysosome (GO:0005764)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	eSLDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q6PKG0

(UniProtKB/Swiss-Prot/P) Details

La-related protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Polysome (GO:0005844)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasmic stress granule (GO:0010494)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	TORC1 complex (GO:0031931)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.995	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.995	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.995	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	0.995	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

Q14671

(UniProtKB/Swiss-Prot/P) Details

Pumilio homolog 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytoplasmic stress granule (GO:0010494)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasmic mRNA processing body (GO:0000932)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

P21580

(UniProtKB/Swiss-Prot/P) Details

Tumor necrosis factor alpha-induced protein 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Lysosome (GO:0005764)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

HPRD, BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

P50749

(UniProtKB/Swiss-Prot/P) Details

Ras association domain-containing protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.96	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Condensed chromosome kinetochore (GO:0000777)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Kinetochore (GO:0000776)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

P25705

(UniProtKB/Swiss-Prot/P) Details

ATP synthase subunit alpha, mitochondrial

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Myelin sheath (GO:0043209)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Proton-transporting ATP synthase complex (GO:0045259)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Proton-transporting ATP synthase complex (GO:0045259)	0.999	Experimental: experimental	Organelle	PubMed
Cytosol	Proton-transporting ATP synthase complex, catalytic core F(1) (GO:0045261)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Unknown: non-traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial matrix (GO:0005759)	1	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial proton-transporting ATP synthase complex (GO:0005753)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Signalosome (GO:0008180)	0.96	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.96	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.96	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.996	Experimental: experimental	eSLDB	PubMed
Membrane	Membrane (GO:0016020)	0.996	Unknown: HDA	GO	PubMed
Membrane	Proton-transporting two-sector ATPase complex (GO:0016469)	0.996	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	0.996	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Organelle inner membrane (GO:0019866)	0.999	Experimental: experimental	Organelle	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.999	Unknown: HDA	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q9UDY2

(UniProtKB/Swiss-Prot/P) Details

Tight junction protein ZO-2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.996	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Human Proteinpedia	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Cell junction (GO:0030054)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Adherens junction (GO:0005912)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Tight junction (GO:0005923)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

P68371

(UniProtKB/Swiss-Prot/P) Details

Tubulin beta-4B chain

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Myelin sheath (GO:0043209)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.86	Unknown: HDA	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.86	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Azurophil granule lumen (GO:0035578)	0.3	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Microtubule (GO:0005874)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.86	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.86	Experimental: experimental	MatrixDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q8WWI1

(UniProtKB/Swiss-Prot/P) Details

LIM domain only protein 7

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Ubiquitin ligase complex (GO:0000151)	1	Unknown: non-traceable author statement	GO	PubMed
Cytosol	Ubiquitin ligase complex (GO:0000151)	1	Experimental: experimental	Organelle	PubMed
Membrane	Cell surface (GO:0009986)	0.958	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: experimental	Organelle	PubMed
Nucleus	Nuclear envelope (GO:0005635)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Apical plasma membrane (GO:0016324)	0.958	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.958	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q9H2G2

(UniProtKB/Swiss-Prot/P) Details

STE20-like serine/threonine-protein kinase

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell leading edge (GO:0031252)	0.94	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

P49796

(UniProtKB/Swiss-Prot/P) Details

Regulator of G-protein signaling 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.996	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.94	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.94	Predicted: inferred from biological aspect of ancestor	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q8IX03

(UniProtKB/Swiss-Prot/P) Details

Protein KIBRA

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.958	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.958	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.958	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Ruffle membrane (GO:0032587)	0.8	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

P32121

(UniProtKB/Swiss-Prot/P) Details

Beta-arrestin-2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Coated pit (GO:0005905)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Unknown: traceable author statement	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.972	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endocytic vesicle (GO:0030139)	0.972	Experimental: inferred from direct assay	GO	PubMed
Membrane	Dendritic spine (GO:0043197)	0.99	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic density (GO:0014069)	0.99	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.99	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.99	Experimental: experimental	Organelle	PubMed
Membrane	Basolateral plasma membrane (GO:0016323)	0.99	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic membrane (GO:0045211)	0.99	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q92609

(UniProtKB/Swiss-Prot/P) Details

TBC1 domain family member 5

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Retromer complex (GO:0030904)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.992	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endosome membrane (GO:0010008)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Autophagic vacuole (GO:0005776)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	AP-2 adaptor complex (GO:0030122)	0.94	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

O00273

(UniProtKB/Swiss-Prot/P) Details

DNA fragmentation factor subunit alpha

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Lipid particle (GO:0005811)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.994	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.994	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.994	Unknown: traceable author statement	GO	PubMed
Nucleus	Nuclear chromatin (GO:0000790)	0.994	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

O14744

(UniProtKB/Swiss-Prot/P) Details

Protein arginine N-methyltransferase 5

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Methylosome (GO:0034709)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.994	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.994	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.994	Unknown: traceable author statement	GO	PubMed
Nucleus	Histone methyltransferase complex (GO:0035097)	0.994	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.8	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q13177

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein kinase PAK 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.958	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.958	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.958	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Postsynaptic density (GO:0014069)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.51	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q9H4L5

(UniProtKB/Swiss-Prot/P) Details

Oxysterol-binding protein-related protein 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear endoplasmic reticulum (GO:0097038)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleolus (GO:0005730)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear membrane (GO:0031965)	0.988	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Filopodium tip (GO:0032433)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.902	Unknown: HDA	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.902	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

Q71U36

(UniProtKB/Swiss-Prot/P) Details

Tubulin alpha-1A chain

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Myelin sheath (GO:0043209)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.3	Unknown: HDA	GO	PubMed
Secretory-pathway	Recycling endosome (GO:0055037)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Microtubule (GO:0005874)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoplasmic microtubule (GO:0005881)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Membrane raft (GO:0045121)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Neuromuscular junction (GO:0031594)	0.657	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q8N1I0

(UniProtKB/Swiss-Prot/P) Details

Dedicator of cytokinesis protein 4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleolus (GO:0005730)	0.988	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.96	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Stereocilium bundle (GO:0032421)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Stereocilium (GO:0032420)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.992	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.992	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

O14757

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein kinase Chk1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Chromosome (GO:0005694)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Condensed nuclear chromosome (GO:0000794)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Chromatin (GO:0000785)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Chromosome, telomeric region (GO:0000781)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular space (GO:0005615)	0.3	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q9BRS2

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein kinase RIO1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Preribosome, small subunit precursor (GO:0030688)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Methyltransferase complex (GO:0034708)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleolus (GO:0005730)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.992	Unknown: traceable author statement	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q9UQM7

(UniProtKB/Swiss-Prot/P) Details

Calcium/calmodulin-dependent protein kinase type II subunit alpha

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Calcium- and calmodulin-dependent protein kinase complex (GO:0005954)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.51	Unknown: HDA	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.51	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endocytic vesicle membrane (GO:0030666)	0.3	Unknown: traceable author statement	GO	PubMed
Membrane	Neuron projection (GO:0043005)	0.999	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Dendritic spine (GO:0043197)	0.999	Experimental: inferred from direct assay	GO	PubMed
Membrane	Postsynaptic density (GO:0014069)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Cell junction (GO:0030054)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Presynaptic membrane (GO:0042734)	0.999	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

P62993

(UniProtKB/Swiss-Prot/P) Details

Growth factor receptor-bound protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Signalosome (GO:0008180)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.86	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.971	Unknown: traceable author statement	GO	PubMed
Membrane	Extrinsic to internal side of plasma membrane (GO:0031234)	0.971	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Grb2-EGFR complex (GO:0070436)	0.971	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.999	Unknown: HDA	GO	PubMed
Cytosol	Vesicle membrane (GO:0012506)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Cell-cell junction (GO:0005911)	0.971	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q12802

(UniProtKB/Swiss-Prot/P) Details

A-kinase anchor protein 13

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cell cortex (GO:0005938)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cortical actin cytoskeleton (GO:0030864)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Actin filament (GO:0005884)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

Q8TEH3

(UniProtKB/Swiss-Prot/P) Details

DENN domain-containing protein 1A

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Neuronal cell body (GO:0043025)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.988	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Clathrin-coated vesicle (GO:0030136)	0.94	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Clathrin coated vesicle membrane (GO:0030665)	0.94	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Dendrite (GO:0030425)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.897	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Cell junction (GO:0030054)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Presynaptic membrane (GO:0042734)	0.897	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

P12830

(UniProtKB/Swiss-Prot/P) Details

Cadherin-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.972	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Trans-Golgi network (GO:0005802)	0.972	Experimental: inferred from mutant phenotype	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cortical actin cytoskeleton (GO:0030864)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Lamellipodium (GO:0030027)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.958	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.958	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.958	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: pTarget method	LOCATE	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Internal side of plasma membrane (GO:0009898)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Lateral plasma membrane (GO:0016328)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Catenin complex (GO:0016342)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Flotillin complex (GO:0016600)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Apical junction complex (GO:0043296)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Cell-cell adherens junction (GO:0005913)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q00536

(UniProtKB/Swiss-Prot/P) Details

Cyclin-dependent kinase 16

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: unspecified method	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Secretory-pathway	Synaptic vesicle (GO:0008021)	0.7	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Unknown: unspecified method	The Human Protein Atlas	PubMed
Membrane	Neuron projection (GO:0043005)	0.986	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.986	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.986	Unknown: unspecified method	The Human Protein Atlas	PubMed
Membrane	Extrinsic to internal side of plasma membrane (GO:0031234)	0.986	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.986	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

P62736

(UniProtKB/Swiss-Prot/P) Details

Actin, aortic smooth muscle

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cell body (GO:0044297)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Smooth muscle contractile fiber (GO:0030485)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Lamellipodium (GO:0030027)	0.982	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Filopodium (GO:0030175)	0.982	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular space (GO:0005615)	0.3	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.982	Experimental: experimental	MatrixDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

P07195

(UniProtKB/Swiss-Prot/P) Details

L-lactate dehydrogenase B chain

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Myelin sheath (GO:0043209)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: experimental	Human Proteinpedia	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.902	Unknown: HDA	GO	PubMed
Membrane	Membrane raft (GO:0045121)	0.902	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

P35232

(UniProtKB/Swiss-Prot/P) Details

Prohibitin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	0.999	Experimental: inferred from direct assay	GO	PubMed
Membrane	Myelin sheath (GO:0043209)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: experimental	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	0.999	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.972	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.972	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.972	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.998	Experimental: experimental	Human Proteinpedia	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.999	Experimental: experimental	eSLDB	PubMed
Membrane	Membrane (GO:0016020)	0.999	Unknown: HDA	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Experimental: inferred from direct assay	GO	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.998	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q6WKZ4

(UniProtKB/Swiss-Prot/P) Details

Rab11 family-interacting protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Recycling endosome (GO:0055037)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Phagocytic vesicle membrane (GO:0030670)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

P46527

(UniProtKB/Swiss-Prot/P) Details

Cyclin-dependent kinase inhibitor 1B

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cul4A-RING ubiquitin ligase complex (GO:0031464)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.3	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

O43765

(UniProtKB/Swiss-Prot/P) Details

Small glutamine-rich tetratricopeptide repeat-containing protein alpha

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

O75643

(UniProtKB/Swiss-Prot/P) Details

U5 small nuclear ribonucleoprotein 200 kDa helicase

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Ribonucleoprotein complex (GO:0030529)	0.999	Experimental: experimental	Organelle	PubMed
Cytosol	U4/U6 x U5 tri-snRNP complex (GO:0046540)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	U5 snRNP (GO:0005682)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Spliceosomal complex (GO:0005681)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Catalytic step 2 spliceosome (GO:0071013)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

HPRD, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q15717

(UniProtKB/Swiss-Prot/P) Details

ELAV-like protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasmic stress granule (GO:0010494)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleolus (GO:0005730)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.998	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q6WCQ1

(UniProtKB/Swiss-Prot/P) Details

Myosin phosphatase Rho-interacting protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Focal adhesion (GO:0005925)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

Q04917

(UniProtKB/Swiss-Prot/P) Details

14-3-3 protein eta

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Human Proteinpedia	PubMed
Membrane	Plasma membrane (GO:0005886)	0.86	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Intercalated disc (GO:0014704)	0.86	Unknown: inferred by curator	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

Q96F07

(UniProtKB/Swiss-Prot/P) Details

Cytoplasmic FMR1-interacting protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Neuron projection (GO:0043005)	0.986	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.986	Unknown: HDA	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.986	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.986	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Synapse (GO:0045202)	0.986	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

P31947

(UniProtKB/Swiss-Prot/P) Details

14-3-3 protein sigma

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.8	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.86	Experimental: experimental	Human Proteinpedia	PubMed
Extracellular	Extracellular space (GO:0005615)	0.3	Unknown: traceable author statement	GO	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	MatrixDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q13625

(UniProtKB/Swiss-Prot/P) Details

Apoptosis-stimulating of p53 protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.987	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.987	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.987	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.987	Unknown: traceable author statement	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q13554

(UniProtKB/Swiss-Prot/P) Details

Calcium/calmodulin-dependent protein kinase type II subunit beta

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Sarcoplasmic reticulum membrane (GO:0033017)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.79	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endocytic vesicle membrane (GO:0030666)	0.3	Unknown: traceable author statement	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Neuron projection (GO:0043005)	0.996	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.996	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Cell junction (GO:0030054)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Synapse (GO:0045202)	0.996	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q6IQ23

(UniProtKB/Swiss-Prot/P) Details

Pleckstrin homology domain-containing family A member 7

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Centrosome (GO:0005813)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.999	Unknown: HDA	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.992	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Zonula adherens (GO:0005915)	0.992	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

P63104

(UniProtKB/Swiss-Prot/P) Details

14-3-3 protein zeta/delta

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.902	Unknown: HDA	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.902	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.902	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Melanosome (GO:0042470)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Extracellular	Extracellular space (GO:0005615)	0.51	Unknown: HDA	GO	PubMed
Extracellular	Blood microparticle (GO:0072562)	0.51	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.86	Experimental: experimental	MatrixDB	PubMed
Cytosol	Vesicle (GO:0031982)	0.999	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.999	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.86	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

Q5VZM2

(UniProtKB/Swiss-Prot/P) Details

Ras-related GTP-binding protein B

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
N/A	Gtr1-Gtr2 GTPase complex (GO:1990131)	0.7	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	EGO complex (GO:0034448)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Lysosome (GO:0005764)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Lysosomal membrane (GO:0005765)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q86SQ0

(UniProtKB/Swiss-Prot/P) Details

Pleckstrin homology-like domain family B member 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell leading edge (GO:0031252)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Basal cortex (GO:0045180)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Intermediate filament cytoskeleton (GO:0045111)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Focal adhesion (GO:0005925)	0.998	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

O43491

(UniProtKB/Swiss-Prot/P) Details

Band 4.1-like protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Signalosome (GO:0008180)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.998	Experimental: experimental	Organelle	PubMed
Cytosol	Spectrin (GO:0008091)	0.998	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.998	Unknown: HDA	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

O00443

(UniProtKB/Swiss-Prot/P) Details

Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Unknown: traceable author statement	GO	PubMed
Cytosol	Phosphatidylinositol 3-kinase complex (GO:0005942)	0.998	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Clathrin-coated vesicle (GO:0030136)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.86	Unknown: HDA	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.86	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Vesicle (GO:0031982)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.998	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q96SB4

(UniProtKB/Swiss-Prot/P) Details

SRSF protein kinase 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear matrix (GO:0016363)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

P35568

(UniProtKB/Swiss-Prot/P) Details

Insulin receptor substrate 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Caveola (GO:0005901)	0.998	Experimental: inferred from direct assay	GO	PubMed
Membrane	Insulin receptor complex (GO:0005899)	0.998	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

HPRD, BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

O94921

(UniProtKB/Swiss-Prot/P) Details

Cyclin-dependent kinase 14

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.998	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytoplasmic cyclin-dependent protein kinase holoenzyme complex (GO:0000308)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.8	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

HPRD, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q9BQA1

(UniProtKB/Swiss-Prot/P) Details

Methylosome protein 50

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from genetic interaction	GO	PubMed
Cytosol	Methylosome (GO:0034709)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Experimental: inferred from genetic interaction	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.992	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.96	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q6ZN04

(UniProtKB/Swiss-Prot/P) Details

RNA-binding protein MEX3B

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasmic mRNA processing body (GO:0000932)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.988	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: experimental	Human Proteinpedia	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q8TEU7

(UniProtKB/Swiss-Prot/P) Details

Rap guanine nucleotide exchange factor 6

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Endocytic vesicle (GO:0030139)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Apical plasma membrane (GO:0016324)	0.998	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

O14639

(UniProtKB/Swiss-Prot/P) Details

Actin-binding LIM protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.8	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Stress fiber (GO:0001725)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Lamellipodium (GO:0030027)	0.8	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

P36873

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Midbody (GO:0030496)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Protein phosphatase type 1 complex (GO:0000164)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	PTW/PP1 phosphatase complex (GO:0072357)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cleavage furrow (GO:0032154)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.86	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial outer membrane (GO:0005741)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.999	Experimental: inferred from mutant phenotype	GO	PubMed
Nucleus	Nuclear chromosome, telomeric region (GO:0000784)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Condensed chromosome kinetochore (GO:0000777)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendritic spine (GO:0043197)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.657	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q5VZ89

(UniProtKB/Swiss-Prot/P) Details

DENN domain-containing protein 4C

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Retromer complex (GO:0030904)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.997	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.973	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.973	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.973	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.958	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Cytoplasmic vesicle membrane (GO:0030659)	0.958	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Insulin-responsive compartment (GO:0032593)	0.958	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.94	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.94	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q8TEW0

(UniProtKB/Swiss-Prot/P) Details

Partitioning defective 3 homolog

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Endomembrane system (GO:0012505)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Neuronal cell body (GO:0043025)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Unknown: traceable author statement	GO	PubMed
Cytosol	Cell cortex (GO:0005938)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.937	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.937	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.937	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.998	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Internode region of axon (GO:0033269)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Axonal growth cone (GO:0044295)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Adherens junction (GO:0005912)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Cell-cell junction (GO:0005911)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Tight junction (GO:0005923)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

Q9NX09

(UniProtKB/Swiss-Prot/P) Details

DNA damage-inducible transcript 4 protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular (GO:0005622)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Experimental: experimental	Human Proteinpedia	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q9H8N7

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein 395

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Lysosome (GO:0005764)	1	Predicted: pTarget method	LOCATE	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q92625

(UniProtKB/Swiss-Prot/P) Details

Ankyrin repeat and SAM domain-containing protein 1A

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.988	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Neuron projection (GO:0043005)	0.7	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q6GQQ9

(UniProtKB/Swiss-Prot/P) Details

OTU domain-containing protein 7B

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q99698

(UniProtKB/Swiss-Prot/P) Details

Lysosomal-trafficking regulator

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Plasma membrane (GO:0005886)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

HPRD, BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q13627

(UniProtKB/Swiss-Prot/P) Details

Dual specificity tyrosine-phosphorylation-regulated kinase 1A

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Fibrillar center (GO:0001650)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.999	Experimental: inferred from direct assay	GO	PubMed
Membrane	Dendrite (GO:0030425)	0.91	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Axon (GO:0030424)	0.91	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

HPRD, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

O60343

(UniProtKB/Swiss-Prot/P) Details

TBC1 domain family member 4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endomembrane system (GO:0012505)	0.999	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Intracellular (GO:0005622)	0.999	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.973	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.973	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.973	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Vesicle (GO:0031982)	0.999	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

P05556

(UniProtKB/Swiss-Prot/P) Details

Integrin beta-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Myelin sheath abaxonal region (GO:0035748)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cleavage furrow (GO:0032154)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.98	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.98	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Recycling endosome (GO:0055037)	0.98	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Melanosome (GO:0042470)	0.98	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Membrane	Glial cell projection (GO:0097386)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Ruffle (GO:0001726)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Ruffle membrane (GO:0032587)	1	Unknown: non-traceable author statement	GO	PubMed
Membrane	Lamellipodium (GO:0030027)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Invadopodium membrane (GO:0071438)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Filopodium (GO:0030175)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Dendritic spine (GO:0043197)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Membrane (GO:0016020)	1	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Membrane raft (GO:0045121)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Unknown: non-traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Sarcolemma (GO:0042383)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	External side of plasma membrane (GO:0009897)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Integrin complex (GO:0008305)	1	Unknown: non-traceable author statement	GO	PubMed
Membrane	Alpha7-beta1 integrin complex (GO:0034677)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Alpha2-beta1 integrin complex (GO:0034666)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Alpha3-beta1 integrin complex (GO:0034667)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Alpha8-beta1 integrin complex (GO:0034678)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Receptor complex (GO:0043235)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.999	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Intercalated disc (GO:0014704)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Neuromuscular junction (GO:0031594)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

P34947

(UniProtKB/Swiss-Prot/P) Details

G protein-coupled receptor kinase 5

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.996	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.996	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear membrane (GO:0031965)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear membrane (GO:0031965)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

P78362

(UniProtKB/Swiss-Prot/P) Details

SRSF protein kinase 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

P0CG47

(UniProtKB/Swiss-Prot/P) Details

Polyubiquitin-B

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Neuronal cell body (GO:0043025)	0.994	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.994	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.994	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytosol (GO:0005829)	0.994	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.86	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial outer membrane (GO:0005741)	0.86	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.956	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.956	Unknown: HDA	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.956	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.956	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.657	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endosome membrane (GO:0010008)	0.657	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endocytic vesicle membrane (GO:0030666)	0.657	Unknown: traceable author statement	GO	PubMed
Membrane	Neuron projection (GO:0043005)	0.972	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.902	Experimental: experimental	MatrixDB	PubMed
Extracellular	Host cell (GO:0043657)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular space (GO:0005615)	0.902	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.972	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.972	Unknown: traceable author statement	GO	PubMed
Cytosol	Vesicle (GO:0031982)	0.994	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.994	Unknown: HDA	GO	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q13164

(UniProtKB/Swiss-Prot/P) Details

Mitogen-activated protein kinase 7

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	PML body (GO:0016605)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

P37231

(UniProtKB/Swiss-Prot/P) Details

Peroxisome proliferator-activated receptor gamma

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	RNA polymerase II transcription factor complex (GO:0090575)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q13309

(UniProtKB/Swiss-Prot/P) Details

S-phase kinase-associated protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	SCF ubiquitin ligase complex (GO:0019005)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.994	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.994	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleolus (GO:0005730)	0.994	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.994	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

P50402

(UniProtKB/Swiss-Prot/P) Details

Emerin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endomembrane system (GO:0012505)	0.994	Experimental: experimental	Organelle	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.994	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nuclear membrane (GO:0031965)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear membrane (GO:0031965)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear outer membrane (GO:0005640)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear inner membrane (GO:0005637)	1	Unknown: non-traceable author statement	GO	PubMed
Nucleus	Nuclear envelope (GO:0005635)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.992	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Cortical endoplasmic reticulum (GO:0032541)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Spindle pole centrosome (GO:0031616)	0.994	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule (GO:0005874)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.902	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.902	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.902	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q9P0L2

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein kinase MARK1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.999	Experimental: experimental	Organelle	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	0.999	Unknown: traceable author statement	GO	PubMed
Membrane	Dendrite (GO:0030425)	0.96	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q9Y2A7

(UniProtKB/Swiss-Prot/P) Details

Nck-associated protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	SCAR complex (GO:0031209)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Filamentous actin (GO:0031941)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Ruffle (GO:0001726)	0.969	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Lamellipodium (GO:0030027)	0.969	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Lamellipodium membrane (GO:0031258)	0.969	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.969	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.999	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.969	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

Q8WYL5

(UniProtKB/Swiss-Prot/P) Details

Protein phosphatase Slingshot homolog 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Midbody (GO:0030496)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cleavage furrow (GO:0032154)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Unknown: unspecified method	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.79	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.79	Unknown: unspecified method	The Human Protein Atlas	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.999	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Growth cone (GO:0030426)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Lamellipodium (GO:0030027)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Membrane (GO:0016020)	0.997	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.997	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.997	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.997	Unknown: unspecified method	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

Q12923

(UniProtKB/Swiss-Prot/P) Details

Tyrosine-protein phosphatase non-receptor type 13

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cell body (GO:0044297)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.958	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.958	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.958	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Lamellipodium (GO:0030027)	0.994	Experimental: inferred from direct assay	GO	PubMed
Membrane	Neuron projection (GO:0043005)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.994	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.994	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.999	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

O75592

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase MYCBP2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.994	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.994	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.994	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Axon (GO:0030424)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Predicted: pTarget method	LOCATE	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.902	Unknown: HDA	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.902	Experimental: experimental	Organelle	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

P40818

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin carboxyl-terminal hydrolase 8

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Midbody (GO:0030496)	0.98	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.79	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Early endosome (GO:0005769)	0.988	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Extrinsic to endosome membrane (GO:0031313)	0.988	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Dendritic spine (GO:0043197)	0.98	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic density (GO:0014069)	0.98	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Extrinsic to plasma membrane (GO:0019897)	0.98	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

O75044

(UniProtKB/Swiss-Prot/P) Details

SLIT-ROBO Rho GTPase-activating protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.995	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.995	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.995	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.995	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.958	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.958	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.958	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.94	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Phagocytic vesicle (GO:0045335)	0.94	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Lamellipodium (GO:0030027)	0.999	Experimental: inferred from direct assay	GO	PubMed
Membrane	Dendritic spine head (GO:0044327)	0.999	Experimental: inferred from direct assay	GO	PubMed
Membrane	Postsynaptic density (GO:0014069)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic membrane (GO:0045211)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q9NYL2

(UniProtKB/Swiss-Prot/P) Details

Mitogen-activated protein kinase kinase kinase 20

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.79	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

P04637

(UniProtKB/Swiss-Prot/P) Details

Cellular tumor antigen p53

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular (GO:0005622)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.972	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.972	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrial matrix (GO:0005759)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear matrix (GO:0016363)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	PML body (GO:0016605)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Transcription factor TFIID complex (GO:0005669)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nuclear chromatin (GO:0000790)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Replication fork (GO:0005657)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

P55957

(UniProtKB/Swiss-Prot/P) Details

BH3-interacting domain death agonist

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	Organelle	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.979	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.979	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.979	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrial outer membrane (GO:0005741)	0.979	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Integral to mitochondrial membrane (GO:0032592)	0.979	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.86	Experimental: experimental	eSLDB	PubMed
Membrane	Membrane (GO:0016020)	0.86	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q9UQL6

(UniProtKB/Swiss-Prot/P) Details

Histone deacetylase 5

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Histone deacetylase complex (GO:0000118)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.96	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

P22681

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase CBL

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Mast cell granule (GO:0042629)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Growth cone (GO:0030426)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane raft (GO:0045121)	0.998	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Experimental: experimental	Organelle	PubMed
Membrane	Flotillin complex (GO:0016600)	0.998	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.998	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

Q9BYG5

(UniProtKB/Swiss-Prot/P) Details

Partitioning defective 6 homolog beta

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cell cortex (GO:0005938)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.972	Experimental: inferred from direct assay	GO	PubMed
Membrane	Apical plasma membrane (GO:0016324)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.999	Unknown: HDA	GO	PubMed
Membrane	Tight junction (GO:0005923)	0.972	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q9NZQ3

(UniProtKB/Swiss-Prot/P) Details

NCK-interacting protein with SH3 domain

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: experimental	eSLDB	PubMed
Nucleus	Signalosome (GO:0008180)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.998	Experimental: experimental	Organelle	PubMed
Cytosol	Intermediate filament (GO:0005882)	0.998	Unknown: non-traceable author statement	GO	PubMed
Membrane	Membrane (GO:0016020)	0.96	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q9UJM3

(UniProtKB/Swiss-Prot/P) Details

ERBB receptor feedback inhibitor 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Extrinsic to internal side of plasma membrane (GO:0031234)	0.7	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q8N3A8

(UniProtKB/Swiss-Prot/P) Details

Poly [ADP-ribose] polymerase 8

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Flemming body (GO:0090543)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Intracellular (GO:0005622)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Cell junction (GO:0030054)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q9HAU0

(UniProtKB/Swiss-Prot/P) Details

Pleckstrin homology domain-containing family A member 5

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.996	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Postsynaptic density (GO:0014069)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.51	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q15418

(UniProtKB/Swiss-Prot/P) Details

Ribosomal protein S6 kinase alpha-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.972	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.972	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.972	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q96CV9

(UniProtKB/Swiss-Prot/P) Details

Optineurin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.937	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.937	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.937	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.994	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.994	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Trans-Golgi network (GO:0005802)	0.994	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Recycling endosome membrane (GO:0055038)	0.994	Unknown: traceable author statement	GO	PubMed
Cytosol	Autophagic vacuole (GO:0005776)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.994	Predicted: inferred from biological aspect of ancestor	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q6P0Q8

(UniProtKB/Swiss-Prot/P) Details

Microtubule-associated serine/threonine-protein kinase 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.997	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	0.997	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.3	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q13671

(UniProtKB/Swiss-Prot/P) Details

Ras and Rab interactor 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Neuronal cell body (GO:0043025)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.994	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.994	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.994	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.994	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear membrane (GO:0031965)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendrite (GO:0030425)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.972	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.972	Experimental: experimental	Organelle	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q8N4C8

(UniProtKB/Swiss-Prot/P) Details

Misshapen-like kinase 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.8	Experimental: inferred from direct assay	GO	PubMed
Membrane	Dendrite (GO:0030425)	0.832	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic density (GO:0014069)	0.832	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Axon (GO:0030424)	0.832	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.997	Unknown: HDA	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.832	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic membrane (GO:0045211)	0.832	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q8WUI4

(UniProtKB/Swiss-Prot/P) Details

Histone deacetylase 7

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.999	Unknown: traceable author statement	GO	PubMed
Nucleus	Histone deacetylase complex (GO:0000118)	0.999	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

P61962

(UniProtKB/Swiss-Prot/P) Details

DDB1- and CUL4-associated factor 7

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	CUL4 RING ubiquitin ligase complex (GO:0080008)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nuclear matrix (GO:0016363)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q96B36

(UniProtKB/Swiss-Prot/P) Details

Proline-rich AKT1 substrate 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	TORC1 complex (GO:0031931)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.937	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.937	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.937	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

Q9H4A3

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein kinase WNK1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Predicted: pTarget method	LOCATE	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.7	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

P49407

(UniProtKB/Swiss-Prot/P) Details

Beta-arrestin-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Coated pit (GO:0005905)	0.986	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.986	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.986	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	0.986	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.931	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Lysosomal membrane (GO:0005765)	0.986	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.931	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle membrane (GO:0030659)	0.931	Unknown: traceable author statement	GO	PubMed
Nucleus	Chromatin (GO:0000785)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Pseudopodium (GO:0031143)	0.984	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendritic spine (GO:0043197)	0.984	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic density (GO:0014069)	0.984	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.984	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.984	Experimental: experimental	Organelle	PubMed
Membrane	Heterotrimeric G-protein complex (GO:0005834)	0.984	Unknown: traceable author statement	GO	PubMed
Membrane	Basolateral plasma membrane (GO:0016323)	0.984	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic membrane (GO:0045211)	0.984	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q14738

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Protein phosphatase type 2A complex (GO:0000159)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.999	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

P62807

(UniProtKB/Swiss-Prot/P) Details

Histone H2B type 1-C/E/F/G/I

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.992	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Unknown: HDA	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Chromosome (GO:0005694)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleosome (GO:0000786)	1	Unknown: non-traceable author statement	GO	PubMed
Extracellular	Extracellular space (GO:0005615)	0.8	Experimental: inferred from direct assay	GO	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	MatrixDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.992	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q99959

(UniProtKB/Swiss-Prot/P) Details

Plakophilin-2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Messenger ribonucleoprotein complex (GO:1990124)	0.996	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Unknown: non-traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cornified envelope (GO:0001533)	0.996	Unknown: traceable author statement	GO	PubMed
Cytosol	Intermediate filament (GO:0005882)	0.996	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Cell junction (GO:0030054)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Adherens junction (GO:0005912)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Cell-cell junction (GO:0005911)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Intercalated disc (GO:0014704)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Desmosome (GO:0030057)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

O43900

(UniProtKB/Swiss-Prot/P) Details

Prickle planar cell polarity protein 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
N/A	Cellular component (GO:0005575)	0.3	Unknown: no biological data available	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.992	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.992	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Centrosome (GO:0005813)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.86	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

P61981

(UniProtKB/Swiss-Prot/P) Details

14-3-3 protein gamma

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Myelin sheath (GO:0043209)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.994	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.994	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.994	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.994	Experimental: experimental	Human Proteinpedia	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.657	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.994	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.657	Unknown: HDA	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, DIP, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

O43524

(UniProtKB/Swiss-Prot/P) Details

Forkhead box protein O3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.992	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.992	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.992	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial matrix (GO:0005759)	0.992	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial outer membrane (GO:0005741)	0.992	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q7L804

(UniProtKB/Swiss-Prot/P) Details

Rab11 family-interacting protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.988	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.988	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.988	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.902	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Recycling endosome membrane (GO:0055038)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle membrane (GO:0030659)	0.902	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.79	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.79	Predicted: PAML algorithm	PA-GOSUB	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

P06899

(UniProtKB/Swiss-Prot/P) Details

Histone H2B type 1-J

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.988	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	0.988	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Chromosome (GO:0005694)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleosome (GO:0000786)	1	Unknown: non-traceable author statement	GO	PubMed
Extracellular	Extracellular space (GO:0005615)	0.8	Experimental: inferred from direct assay	GO	PubMed
Membrane	Membrane (GO:0016020)	0.96	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q02750

(UniProtKB/Swiss-Prot/P) Details

Dual specificity mitogen-activated protein kinase kinase 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.3	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.3	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.931	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.931	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	0.931	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Late endosome (GO:0005770)	0.931	Unknown: traceable author statement	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.972	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.972	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Focal adhesion (GO:0005925)	0.972	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

P56524

(UniProtKB/Swiss-Prot/P) Details

Histone deacetylase 4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.997	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Transcriptional repressor complex (GO:0017053)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Histone deacetylase complex (GO:0000118)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Z disc (GO:0030018)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	A band (GO:0031672)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Actomyosin (GO:0042641)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Neuromuscular junction (GO:0031594)	0.3	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

O60292

(UniProtKB/Swiss-Prot/P) Details

Signal-induced proliferation-associated 1-like protein 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Apical part of cell (GO:0045177)	0.988	Experimental: inferred from mutant phenotype	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.988	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nuclear membrane (GO:0031965)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Stress fiber (GO:0001725)	0.988	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.86	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.86	Experimental: experimental	MatrixDB	PubMed
Membrane	Apical plasma membrane (GO:0016324)	0.86	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

O14920

(UniProtKB/Swiss-Prot/P) Details

Inhibitor of nuclear factor kappa-B kinase subunit beta

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	IkappaB kinase complex (GO:0008385)	0.998	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane raft (GO:0045121)	0.937	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Internal side of plasma membrane (GO:0009898)	0.937	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	CD40 receptor complex (GO:0035631)	0.937	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

P31946

Interaction Score

P04049

(UniProtKB/Swiss-Prot/P) Details

RAF proto-oncogene serine/threonine-protein kinase

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.982	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.982	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.982	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.86	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrial outer membrane (GO:0005741)	0.86	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.988	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.7	Predicted: inferred from physical interaction	GO	PubMed
Membrane	Pseudopodium (GO:0031143)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.86	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, DIP, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

Q13469

(UniProtKB/Swiss-Prot/P) Details

Nuclear factor of activated T-cells, cytoplasmic 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear transcription factor complex (GO:0044798)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nuclear chromatin (GO:0000790)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

O95817

(UniProtKB/Swiss-Prot/P) Details

BAG family molecular chaperone regulator 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Z disc (GO:0030018)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Neuron projection (GO:0043005)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.972	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.972	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

O94906

(UniProtKB/Swiss-Prot/P) Details

Pre-mRNA-processing factor 6

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Ribonucleoprotein complex (GO:0030529)	0.992	Experimental: experimental	Organelle	PubMed
Cytosol	U4/U6 x U5 tri-snRNP complex (GO:0046540)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	U5 snRNP (GO:0005682)	0.992	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Spliceosomal complex (GO:0005681)	1	Unknown: non-traceable author statement	GO	PubMed
Nucleus	Catalytic step 2 spliceosome (GO:0071013)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q86X29

(UniProtKB/Swiss-Prot/P) Details

Lipolysis-stimulated lipoprotein receptor

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.987	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.987	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.987	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.931	Experimental: experimental	MatrixDB	PubMed
Extracellular	Low-density lipoprotein particle (GO:0034362)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Very-low-density lipoprotein particle (GO:0034361)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Chylomicron (GO:0042627)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.987	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.987	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.987	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.987	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.987	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q9H1K1

(UniProtKB/Swiss-Prot/P) Details

Iron-sulfur cluster assembly enzyme ISCU, mitochondrial

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Predicted: pTarget method	LOCATE	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrial matrix (GO:0005759)	0.999	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.86	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.86	Experimental: experimental	Human Proteinpedia	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q9Y297

(UniProtKB/Swiss-Prot/P) Details

F-box/WD repeat-containing protein 1A

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	SCF ubiquitin ligase complex (GO:0019005)	0.997	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.86	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.86	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.8	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q13049

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase TRIM32

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.997	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Striated muscle myosin thick filament (GO:0005863)	0.997	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Intermediate filament cytoskeleton (GO:0045111)	0.997	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

Q14C86

(UniProtKB/Swiss-Prot/P) Details

GTPase-activating protein and VPS9 domain-containing protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.996	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.79	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.79	Predicted: PAML algorithm	PA-GOSUB	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

P06213

(UniProtKB/Swiss-Prot/P) Details

Insulin receptor

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Neuronal cell body membrane (GO:0032809)	0.987	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Intracellular (GO:0005622)	0.987	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.987	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear envelope (GO:0005635)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear lumen (GO:0031981)	0.96	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endosome membrane (GO:0010008)	0.3	Unknown: traceable author statement	GO	PubMed
Membrane	Dendrite membrane (GO:0032590)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Unknown: inferred by curator	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: pTarget method	LOCATE	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	External side of plasma membrane (GO:0009897)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Caveola (GO:0005901)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Receptor complex (GO:0043235)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Insulin receptor complex (GO:0005899)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.987	Unknown: HDA	GO	PubMed

Interaction Source Database:

HPRD, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

P29074

(UniProtKB/Swiss-Prot/P) Details

Tyrosine-protein phosphatase non-receptor type 4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.992	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.86	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.86	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.992	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Internal side of plasma membrane (GO:0009898)	0.96	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

Q9UJ41

(UniProtKB/Swiss-Prot/P) Details

Rab5 GDP/GTP exchange factor

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.996	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleolus (GO:0005730)	0.988	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Recycling endosome (GO:0055037)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	0.902	Experimental: inferred from mutant phenotype	GO	PubMed
Secretory-pathway	Early endosome membrane (GO:0031901)	0.902	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

Q8NFA0

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin carboxyl-terminal hydrolase 32

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.996	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.96	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q7Z6J0

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase SH3RF1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Intermediate filament cytoskeleton (GO:0045111)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Lamellipodium (GO:0030027)	0.7	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q8N5S9

(UniProtKB/Swiss-Prot/P) Details

Calcium/calmodulin-dependent protein kinase kinase 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.997	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.973	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.973	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.973	Predicted: PAML algorithm	PA-GOSUB	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

P00533

(UniProtKB/Swiss-Prot/P) Details

Epidermal growth factor receptor

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Cell surface (GO:0009986)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Endomembrane system (GO:0012505)	0.972	Experimental: experimental	Organelle	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.972	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.994	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.994	Experimental: experimental	Organelle	PubMed
Nucleus	Nuclear membrane (GO:0031965)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.994	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Early endosome membrane (GO:0031901)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endosome membrane (GO:0010008)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Clathrin coated vesicle membrane (GO:0030665)	0.999	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.86	Unknown: non-traceable author statement	GO	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Membrane raft (GO:0045121)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	AP-2 adaptor complex (GO:0030122)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: pTarget method	LOCATE	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Shc-EGFR complex (GO:0070435)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Receptor complex (GO:0043235)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Apical plasma membrane (GO:0016324)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Basolateral plasma membrane (GO:0016323)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Unknown: HDA	GO	PubMed
Membrane	Synapse (GO:0045202)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

Q8N3F8

(UniProtKB/Swiss-Prot/P) Details

MICAL-like protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Trans-Golgi network (GO:0005802)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Recycling endosome membrane (GO:0055038)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Late endosome membrane (GO:0031902)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Late endosome (GO:0005770)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Extrinsic to membrane (GO:0019898)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q00587

(UniProtKB/Swiss-Prot/P) Details

Cdc42 effector protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endomembrane system (GO:0012505)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.994	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.994	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.994	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Focal adhesion (GO:0005925)	0.994	Unknown: HDA	GO	PubMed
Membrane	Cell-cell adherens junction (GO:0005913)	0.994	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q96GG9

(UniProtKB/Swiss-Prot/P) Details

DCN1-like protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Ubiquitin ligase complex (GO:0000151)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

P30305

(UniProtKB/Swiss-Prot/P) Details

M-phase inducer phosphatase 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.999	Unknown: traceable author statement	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.79	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.999	Experimental: experimental	eSLDB	PubMed
Cytosol	Spindle pole (GO:0000922)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	0.999	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, DIP, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

P05129

(UniProtKB/Swiss-Prot/P) Details

Protein kinase C gamma type

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular (GO:0005622)	0.998	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.998	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendrite (GO:0030425)	0.969	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Postsynaptic density (GO:0014069)	0.969	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.969	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Cell-cell junction (GO:0005911)	0.969	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Synaptic membrane (GO:0097060)	0.969	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q9NQT8

(UniProtKB/Swiss-Prot/P) Details

Kinesin-like protein KIF13B

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Kinesin complex (GO:0005871)	0.998	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Microtubule (GO:0005874)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Microvillus (GO:0005902)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Axon (GO:0030424)	0.902	Experimental: inferred from direct assay	GO	PubMed
Membrane	Paranode region of axon (GO:0033270)	0.902	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q96JH8

(UniProtKB/Swiss-Prot/P) Details

Ras-associating and dilute domain-containing protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.996	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear membrane (GO:0031965)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Microtubule (GO:0005874)	0.996	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

HPRD, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q9Y2U5

(UniProtKB/Swiss-Prot/P) Details

Mitogen-activated protein kinase kinase kinase 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.996	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.988	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q3LXA3

(UniProtKB/Swiss-Prot/P) Details

Triokinase/FMN cyclase

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.86	Unknown: HDA	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.86	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.998	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

Q9NYF0

(UniProtKB/Swiss-Prot/P) Details

Dapper homolog 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.994	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.994	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Beta-catenin destruction complex (GO:0030877)	0.994	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.994	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Cell junction (GO:0030054)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Synapse (GO:0045202)	0.51	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

O15264

(UniProtKB/Swiss-Prot/P) Details

Mitogen-activated protein kinase 13

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.996	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleolus (GO:0005730)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

P0CG48

(UniProtKB/Swiss-Prot/P) Details

Polyubiquitin-C

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Myelin sheath (GO:0043209)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.969	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.969	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytosol (GO:0005829)	0.969	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrial outer membrane (GO:0005741)	0.3	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.956	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.956	Unknown: HDA	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.956	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.956	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.657	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endosome membrane (GO:0010008)	0.657	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endocytic vesicle membrane (GO:0030666)	0.657	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.902	Experimental: experimental	MatrixDB	PubMed
Extracellular	Host cell (GO:0043657)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular space (GO:0005615)	0.902	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.902	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.902	Unknown: traceable author statement	GO	PubMed
Cytosol	Vesicle (GO:0031982)	0.969	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.969	Unknown: HDA	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.999

Q14739

(UniProtKB/Swiss-Prot/P) Details

Lamin-B receptor

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endomembrane system (GO:0012505)	0.96	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nuclear membrane (GO:0031965)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear membrane (GO:0031965)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Integral to nuclear inner membrane (GO:0005639)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Integral to nuclear inner membrane (GO:0005639)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nuclear envelope (GO:0005635)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.91	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Integral to endoplasmic reticulum membrane (GO:0030176)	0.91	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.972	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.972	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.972	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Organelle inner membrane (GO:0019866)	0.96	Experimental: experimental	Organelle	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.999

P13569

(UniProtKB/Swiss-Prot/P) Details

Cystic fibrosis transmembrane conductance regulator

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.972	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.972	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.94	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum Sec complex (GO:0031205)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi-associated vesicle membrane (GO:0030660)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Recycling endosome (GO:0055037)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Recycling endosome membrane (GO:0055038)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Early endosome membrane (GO:0031901)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endosome membrane (GO:0010008)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Lysosomal membrane (GO:0005765)	0.972	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Clathrin coated vesicle membrane (GO:0030665)	1	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Chloride channel complex (GO:0034707)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Apical plasma membrane (GO:0016324)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.999

Q9BY84

(UniProtKB/Swiss-Prot/P) Details

Dual specificity protein phosphatase 16

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.994	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.994	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.994	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.994	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.3	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

0.999

Q6UUV7

(UniProtKB/Swiss-Prot/P) Details

CREB-regulated transcription coactivator 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.988	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.988	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.996	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.999

P11274

(UniProtKB/Swiss-Prot/P) Details

Breakpoint cluster region protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.971	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.971	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.971	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.988	Experimental: inferred from direct assay	GO	PubMed
Membrane	Postsynaptic density (GO:0014069)	0.956	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.956	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.971	Unknown: HDA	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.956	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic membrane (GO:0045211)	0.956	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.999

O94763

(UniProtKB/Swiss-Prot/P) Details

Unconventional prefoldin RPB5 interactor 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	DNA-directed RNA polymerase II, core complex (GO:0005665)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	RNA polymerase complex (GO:0030880)	1	Experimental: experimental	Organelle	PubMed
Membrane	Dendrite (GO:0030425)	0.3	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.999

P27448

(UniProtKB/Swiss-Prot/P) Details

MAP/microtubule affinity-regulating kinase 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.971	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.971	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.971	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.982	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.982	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nuclear membrane (GO:0031965)	0.982	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Dendrite (GO:0030425)	0.96	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.971	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

0.999

Q9Y2H9

(UniProtKB/Swiss-Prot/P) Details

Microtubule-associated serine/threonine-protein kinase 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular (GO:0005622)	0.991	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.991	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.991	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.991	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.991	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.86	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.86	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.999

O75420

(UniProtKB/Swiss-Prot/P) Details

GRB10-interacting GYF protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	0.982	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.982	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.982	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Organelle inner membrane (GO:0019866)	0.992	Experimental: experimental	Organelle	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.999

Q01433

(UniProtKB/Swiss-Prot/P) Details

AMP deaminase 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
N/A	Cellular component (GO:0005575)	0.3	Unknown: no biological data available	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.999

Q9UPU9

(UniProtKB/Swiss-Prot/P) Details

Protein Smaug homolog 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasmic mRNA processing body (GO:0000932)	0.988	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.988	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Fibrillar center (GO:0001650)	0.94	Experimental: inferred from direct assay	GO	PubMed
Membrane	Dendrite (GO:0030425)	0.98	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.98	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.98	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Synapse (GO:0045202)	0.98	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.999

Q92538

(UniProtKB/Swiss-Prot/P) Details

Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell leading edge (GO:0031252)	0.958	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.994	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.994	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.994	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Lipid particle (GO:0005811)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.994	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum lumen (GO:0005788)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum-Golgi intermediate compartment (GO:0005793)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi stack (GO:0005795)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Cis-Golgi network (GO:0005801)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Trans-Golgi network (GO:0005802)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Peroxisome (GO:0005777)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.958	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.958	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

0.999

P21359

(UniProtKB/Swiss-Prot/P) Details

Neurofibromin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.981	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.981	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.981	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.981	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.79	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	0.79	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendrite (GO:0030425)	0.997	Experimental: inferred from direct assay	GO	PubMed
Membrane	Axon (GO:0030424)	0.997	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.997	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.997	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Intrinsic to internal side of plasma membrane (GO:0031235)	0.997	Predicted: inferred from biological aspect of ancestor	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.999

P17812

(UniProtKB/Swiss-Prot/P) Details

CTP synthase 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	0.997	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.999

Q96PU5

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase NEDD4-like

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular (GO:0005622)	0.991	Unknown: inferred by curator	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.991	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.991	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.991	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.991	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.79	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.79	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.853	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.853	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Multivesicular body (GO:0005771)	0.853	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.991	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.999

Q00537

(UniProtKB/Swiss-Prot/P) Details

Cyclin-dependent kinase 17

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.995	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.995	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.995	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.995	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.999

Q9P0V3

(UniProtKB/Swiss-Prot/P) Details

SH3 domain-binding protein 4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Coated pit (GO:0005905)	0.971	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.971	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.971	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	0.958	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.958	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.958	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Clathrin-coated vesicle (GO:0030136)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.971	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.999

Q86V48

(UniProtKB/Swiss-Prot/P) Details

Leucine zipper protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.978	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.978	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.978	Unknown: unspecified method	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.978	Unknown: unspecified method	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.958	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.958	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.958	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	0.978	Unknown: unspecified method	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.978	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.999

Q13136

(UniProtKB/Swiss-Prot/P) Details

Liprin-alpha-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendrite (GO:0030425)	0.986	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Axon (GO:0030424)	0.986	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.986	Experimental: inferred from direct assay	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.986	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Presynaptic active zone (GO:0048786)	0.986	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.999

Q13188

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein kinase 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.992	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.992	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.987	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.987	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.987	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.987	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intermediate filament cytoskeleton (GO:0045111)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.999

Q07002

(UniProtKB/Swiss-Prot/P) Details

Cyclin-dependent kinase 18

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
N/A	Cellular component (GO:0005575)	0.3	Unknown: no biological data available	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.995	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.995	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.995	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	0.995	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.999

Q8TEJ3

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase SH3RF3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Centrosome (GO:0005813)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.999

P49802

(UniProtKB/Swiss-Prot/P) Details

Regulator of G-protein signaling 7

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.988	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.988	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.7	Predicted: inferred from biological aspect of ancestor	GO	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.999

O94915

(UniProtKB/Swiss-Prot/P) Details

Protein furry homolog-like

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cell cortex (GO:0005938)	0.988	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Site of polarized growth (GO:0030427)	0.7	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Extracellular	Intercellular bridge (GO:0045171)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

0.999

P55040

(UniProtKB/Swiss-Prot/P) Details

GTP-binding protein GEM

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Midbody (GO:0030496)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.992	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Mitotic spindle (GO:0072686)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Spindle midzone (GO:0051233)	0.992	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.998	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Internal side of plasma membrane (GO:0009898)	0.998	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

HPRD, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.999

Q14258

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin/ISG15 ligase TRIM25

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.988	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.988	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.999

Q07352

(UniProtKB/Swiss-Prot/P) Details

mRNA decay activator protein ZFP36L1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.988	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasmic mRNA processing body (GO:0000932)	0.988	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.988	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.999

Q6P1J9

(UniProtKB/Swiss-Prot/P) Details

Parafibromin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.988	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytosol (GO:0005829)	0.988	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.999	Unknown: traceable author statement	GO	PubMed
Nucleus	Cdc73/Paf1 complex (GO:0016593)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear chromosome, telomeric region (GO:0000784)	0.999	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.999

Q16890

(UniProtKB/Swiss-Prot/P) Details

Tumor protein D53

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.998	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Cell junction (GO:0030054)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

0.999

Q9UQ88

(UniProtKB/Swiss-Prot/P) Details

Cyclin-dependent kinase 11A

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.987	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.987	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.987	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.987	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.999

Q8WUA7

(UniProtKB/Swiss-Prot/P) Details

TBC1 domain family member 22A

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endomembrane system (GO:0012505)	0.982	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Intracellular (GO:0005622)	0.982	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.982	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Integral to membrane (GO:0016021)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.999

P55916

(UniProtKB/Swiss-Prot/P) Details

Mitochondrial uncoupling protein 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.997	Experimental: experimental	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.997	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.997	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.997	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	0.997	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.988	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.988	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Organelle inner membrane (GO:0019866)	0.96	Experimental: experimental	Organelle	PubMed

Interaction Source Database:

HPRD, BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.999

Q96NE9

(UniProtKB/Swiss-Prot/P) Details

FERM domain-containing protein 6

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.981	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.981	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.981	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.981	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Apical junction complex (GO:0043296)	0.51	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.999

Q8NHY2

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase COP1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cul4A-RING ubiquitin ligase complex (GO:0031464)	0.987	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.987	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.987	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.987	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.971	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.971	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.971	Unknown: traceable author statement	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.971	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.3	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.999

Q99759

(UniProtKB/Swiss-Prot/P) Details

Mitogen-activated protein kinase kinase kinase 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.987	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.987	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.987	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.987	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.982	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.982	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.982	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

HPRD, DIP, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.999

Q07021

(UniProtKB/Swiss-Prot/P) Details

Complement component 1 Q subcomponent-binding protein, mitochondrial

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.94	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.94	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: experimental	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Predicted: pTarget method	LOCATE	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial matrix (GO:0005759)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.86	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Presynaptic active zone (GO:0048786)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.999

P07101

(UniProtKB/Swiss-Prot/P) Details

Tyrosine 3-monooxygenase

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Perikaryon (GO:0043204)	0.987	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.987	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.987	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.987	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Smooth endoplasmic reticulum (GO:0005790)	0.994	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.994	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Melanosome membrane (GO:0033162)	0.994	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Synaptic vesicle (GO:0008021)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Neuron projection (GO:0043005)	0.98	Experimental: inferred from direct assay	GO	PubMed
Membrane	Dendrite (GO:0030425)	0.98	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Internal side of plasma membrane (GO:0009898)	0.98	Experimental: inferred from direct assay	GO	PubMed
Membrane	Terminal button (GO:0043195)	0.98	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.998

Q16204

(UniProtKB/Swiss-Prot/P) Details

Coiled-coil domain-containing protein 6

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.992	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.992	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.998

O95544

(UniProtKB/Swiss-Prot/P) Details

NAD kinase

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.987	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.987	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.987	Unknown: traceable author statement	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.987	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.998

P15336

(UniProtKB/Swiss-Prot/P) Details

Cyclic AMP-dependent transcription factor ATF-2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.94	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial outer membrane (GO:0005741)	0.8	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Site of double-strand break (GO:0035861)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.998

Q8NEY1

(UniProtKB/Swiss-Prot/P) Details

Neuron navigator 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.971	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.971	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	0.971	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Microtubule (GO:0005874)	0.971	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Initial segment (GO:0043194)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.998

P09622

(UniProtKB/Swiss-Prot/P) Details

Dihydrolipoyl dehydrogenase, mitochondrial

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Myelin sheath (GO:0043209)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Pyruvate dehydrogenase complex (GO:0045254)	0.96	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial matrix (GO:0005759)	0.999	Unknown: traceable author statement	GO	PubMed
Cytosol	Oxoglutarate dehydrogenase complex (GO:0045252)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.992	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Acrosomal matrix (GO:0043159)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Motile cilium (GO:0031514)	0.51	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.998

Q9UKV3

(UniProtKB/Swiss-Prot/P) Details

Apoptotic chromatin condensation inducer in the nucleus

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
N/A	ASAP complex (GO:0061574)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.998

P19320

(UniProtKB/Swiss-Prot/P) Details

Vascular cell adhesion protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Cell surface (GO:0009986)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Apical part of cell (GO:0045177)	0.972	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Podosome (GO:0002102)	0.972	Experimental: inferred from direct assay	GO	PubMed
Membrane	Microvillus (GO:0005902)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Filopodium (GO:0030175)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.988	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.988	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.988	Experimental: inferred from direct assay	GO	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Sarcolemma (GO:0042383)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	External side of plasma membrane (GO:0009897)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex (GO:0071065)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.972	Unknown: HDA	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

0.998

Q9NYA4

(UniProtKB/Swiss-Prot/P) Details

Myotubularin-related protein 4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.958	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.958	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.958	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.86	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Early endosome membrane (GO:0031901)	0.86	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.86	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.998

Q9Y4H2

(UniProtKB/Swiss-Prot/P) Details

Insulin receptor substrate 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Aggresome (GO:0016235)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytosol (GO:0005829)	0.988	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.79	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.7	Predicted: inferred from biological aspect of ancestor	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

0.998

O43521

(UniProtKB/Swiss-Prot/P) Details

Bcl-2-like protein 11

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Mitochondrion	Bcl-2 family protein complex (GO:0097136)	0.853	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Endomembrane system (GO:0012505)	0.956	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.956	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.956	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytosol (GO:0005829)	0.956	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.853	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Mitochondrion	Mitochondrial outer membrane (GO:0005741)	0.853	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.958	Experimental: experimental	eSLDB	PubMed
Membrane	Extrinsic to membrane (GO:0019898)	0.958	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.958	Predicted: PAML algorithm	PA-GOSUB	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.998

P52209

(UniProtKB/Swiss-Prot/P) Details

6-phosphogluconate dehydrogenase, decarboxylating

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.996	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	0.996	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.3	Unknown: HDA	GO	PubMed
Cytosol	Intermediate filament cytoskeleton (GO:0045111)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.996	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.998

Q92783

(UniProtKB/Swiss-Prot/P) Details

Signal transducing adapter molecule 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.958	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.958	Unknown: traceable author statement	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.958	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Early endosome membrane (GO:0031901)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	ESCRT-0 complex (GO:0033565)	0.51	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.998

Q9H4G0

(UniProtKB/Swiss-Prot/P) Details

Band 4.1-like protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.987	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.987	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.987	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.987	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.992	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.992	Experimental: experimental	Human Proteinpedia	PubMed
Membrane	Plasma membrane (GO:0005886)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.998

Q9UBF8

(UniProtKB/Swiss-Prot/P) Details

Phosphatidylinositol 4-kinase beta

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.931	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.931	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.931	Unknown: traceable author statement	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.86	Experimental: experimental	eSLDB	PubMed
Mitochondrion	Mitochondrial outer membrane (GO:0005741)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.999	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Rough endoplasmic reticulum membrane (GO:0030867)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.999	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.999	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.94	Experimental: experimental	eSLDB	PubMed
Membrane	Membrane (GO:0016020)	0.94	Predicted: inferred from biological aspect of ancestor	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

0.998

O94875

(UniProtKB/Swiss-Prot/P) Details

Sorbin and SH3 domain-containing protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.897	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.997	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.997	Unknown: non-traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.997	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.997	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.997	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Z disc (GO:0030018)	0.897	Unknown: non-traceable author statement	GO	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	0.897	Unknown: traceable author statement	GO	PubMed
Membrane	Lamellipodium (GO:0030027)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Apical plasma membrane (GO:0016324)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.657	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.997

P26045

(UniProtKB/Swiss-Prot/P) Details

Tyrosine-protein phosphatase non-receptor type 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.987	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.987	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.987	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.987	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.86	Unknown: traceable author statement	GO	PubMed
Membrane	Internal side of plasma membrane (GO:0009898)	0.86	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

0.997

A2A3K4

(UniProtKB/Swiss-Prot/P) Details

Protein tyrosine phosphatase domain-containing protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.973	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.973	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.973	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.997

P78527

(UniProtKB/Swiss-Prot/P) Details

DNA-dependent protein kinase catalytic subunit

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.86	Unknown: traceable author statement	GO	PubMed
Cytosol	Nonhomologous end joining complex (GO:0070419)	0.86	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Transcription factor complex (GO:0005667)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Nucleus	Protein-DNA complex (GO:0032993)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	DNA-dependent protein kinase-DNA ligase 4 complex (GO:0005958)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear chromosome, telomeric region (GO:0000784)	1	Unknown: HDA	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.96	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.96	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.997

Q13470

(UniProtKB/Swiss-Prot/P) Details

Non-receptor tyrosine-protein kinase TNK1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.958	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.958	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.958	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.988	Experimental: inferred from direct assay	GO	PubMed
Membrane	Extrinsic to internal side of plasma membrane (GO:0031234)	0.988	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.997

Q7L8J4

(UniProtKB/Swiss-Prot/P) Details

SH3 domain-binding protein 5-like

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.982	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.982	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.982	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.91	Predicted: pTarget method	LOCATE	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.91	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.997

Q9UQC2

(UniProtKB/Swiss-Prot/P) Details

GRB2-associated-binding protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.958	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.958	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.958	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.997

Q9Y2H2

(UniProtKB/Swiss-Prot/P) Details

Phosphatidylinositide phosphatase SAC2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Coated pit (GO:0005905)	0.958	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Neuronal cell body (GO:0043025)	0.958	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.958	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Secretory-pathway	Recycling endosome (GO:0055037)	0.992	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	0.992	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Early endosome membrane (GO:0031901)	0.992	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Clathrin-coated endocytic vesicle (GO:0045334)	0.992	Experimental: inferred from direct assay	GO	PubMed
Membrane	Dendrite (GO:0030425)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Axon (GO:0030424)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.997

P55196

(UniProtKB/Swiss-Prot/P) Details

Afadin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.94	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytosol (GO:0005829)	0.94	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.998	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Cell junction (GO:0030054)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Cell-cell junction (GO:0005911)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Cell-cell adherens junction (GO:0005913)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

0.997

Q99683

(UniProtKB/Swiss-Prot/P) Details

Mitogen-activated protein kinase kinase kinase 5

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.987	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.987	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.987	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.987	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.8	Experimental: inferred from mutant phenotype	GO	PubMed
Membrane	External side of plasma membrane (GO:0009897)	0.3	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.997

Q96P47

(UniProtKB/Swiss-Prot/P) Details

Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.91	Predicted: inferred from sequence orthology	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.91	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: inferred from sequence orthology	GO	PubMed
Membrane	Cell periphery (GO:0071944)	0.937	Predicted: inferred from sequence orthology	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.937	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.937	Predicted: PAML algorithm	PA-GOSUB	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.997

Q9Y3R0

(UniProtKB/Swiss-Prot/P) Details

Glutamate receptor-interacting protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.937	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.937	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.937	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.853	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.853	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Recycling endosome (GO:0055037)	0.853	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Neuron projection (GO:0043005)	0.994	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Dendrite (GO:0030425)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane raft (GO:0045121)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.994	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.994	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Cell junction (GO:0030054)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic membrane (GO:0045211)	0.994	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.997

Q9H9C1

(UniProtKB/Swiss-Prot/P) Details

Spermatogenesis-defective protein 39 homolog

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.988	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.988	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Recycling endosome (GO:0055037)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Late endosome (GO:0005770)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	HOPS complex (GO:0030897)	0.988	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.997

P19634

(UniProtKB/Swiss-Prot/P) Details

Sodium/hydrogen exchanger 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.902	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.937	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.937	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.937	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Lamellipodium (GO:0030027)	1	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Cation-transporting ATPase complex (GO:0090533)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Membrane raft (GO:0045121)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	T-tubule (GO:0030315)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Apical plasma membrane (GO:0016324)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Basolateral plasma membrane (GO:0016323)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.902	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Unknown: HDA	GO	PubMed
Membrane	Intercalated disc (GO:0014704)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

HPRD, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.997

Q96MP8

(UniProtKB/Swiss-Prot/P) Details

BTB/POZ domain-containing protein KCTD7

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.958	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.958	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.958	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.8	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.997

Q9C0B0

(UniProtKB/Swiss-Prot/P) Details

RING finger protein unkempt homolog

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Polysome (GO:0005844)	0.972	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.972	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.973	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.973	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.973	Predicted: PAML algorithm	PA-GOSUB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.997

Q9UJF2

(UniProtKB/Swiss-Prot/P) Details

Ras GTPase-activating protein nGAP

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.981	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.981	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.981	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.981	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.996	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Intrinsic to internal side of plasma membrane (GO:0031235)	0.996	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.997

Q5TCZ1

(UniProtKB/Swiss-Prot/P) Details

SH3 and PX domain-containing protein 2A

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.987	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.987	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.987	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Podosome (GO:0002102)	0.987	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell projection (GO:0042995)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.51	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.997

Q5PRF9

(UniProtKB/Swiss-Prot/P) Details

Protein Smaug homolog 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasmic mRNA processing body (GO:0000932)	0.988	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.988	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.79	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.997

P68400

(UniProtKB/Swiss-Prot/P) Details

Casein kinase II subunit alpha

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.958	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	0.958	Unknown: traceable author statement	GO	PubMed
Cytosol	Protein kinase CK2 complex (GO:0005956)	0.958	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	NuRD complex (GO:0016581)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	PcG protein complex (GO:0031519)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Sin3 complex (GO:0016580)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.3	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

0.997

Q15678

(UniProtKB/Swiss-Prot/P) Details

Tyrosine-protein phosphatase non-receptor type 14

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.958	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.958	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.992	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.958	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

0.996

Q9ULT8

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase HECTD1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.973	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.973	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.973	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleolus (GO:0005730)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.996

Q6VAB6

(UniProtKB/Swiss-Prot/P) Details

Kinase suppressor of Ras 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.91	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.91	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: pTarget method	LOCATE	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.7	Predicted: inferred from biological aspect of ancestor	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.996

Q86X27

(UniProtKB/Swiss-Prot/P) Details

Ras-specific guanine nucleotide-releasing factor RalGPS2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.956	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.956	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.956	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.956	Unknown: unspecified method	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.79	Unknown: unspecified method	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.3	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.996

P49736

(UniProtKB/Swiss-Prot/P) Details

DNA replication licensing factor MCM2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Chromosome (GO:0005694)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nuclear chromosome, telomeric region (GO:0000784)	1	Unknown: HDA	GO	PubMed
Nucleus	MCM complex (GO:0042555)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear origin of replication recognition complex (GO:0005664)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Chromatin (GO:0000785)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.996

O00422

(UniProtKB/Swiss-Prot/P) Details

Histone deacetylase complex subunit SAP18

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
N/A	ASAP complex (GO:0061574)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Exon-exon junction complex (GO:0035145)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Histone deacetylase complex (GO:0000118)	1	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.996

Q9HCG8

(UniProtKB/Swiss-Prot/P) Details

Pre-mRNA-splicing factor CWC22 homolog

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Spliceosomal complex (GO:0005681)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	U2-type catalytic step 1 spliceosome (GO:0071006)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	U2-type catalytic step 2 spliceosome (GO:0071007)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Catalytic step 2 spliceosome (GO:0071013)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.996

Q9H3P2

(UniProtKB/Swiss-Prot/P) Details

Negative elongation factor A

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	NELF complex (GO:0032021)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.996

Q8WX92

(UniProtKB/Swiss-Prot/P) Details

Negative elongation factor B

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.96	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	NELF complex (GO:0032021)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.996

Q5TCX8

(UniProtKB/Swiss-Prot/P) Details

Mitogen-activated protein kinase kinase kinase 21

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
N/A	Cellular component (GO:0005575)	0.3	Unknown: no biological data available	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.982	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.982	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.982	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

0.996

Q15287

(UniProtKB/Swiss-Prot/P) Details

RNA-binding protein with serine-rich domain 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
N/A	ASAP complex (GO:0061574)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.958	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.958	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.958	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Exon-exon junction complex (GO:0035145)	1	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

0.996

G8JLD5

(UniProtKB/TrEmbl/P) Details

Dynamin-1-like protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.988	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytosol (GO:0005829)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.995

P32418

(UniProtKB/Swiss-Prot/P) Details

Sodium/calcium exchanger 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Mitochondrion	Mitochondrion (GO:0005739)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Z disc (GO:0030018)	0.79	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Microtubule (GO:0005874)	0.79	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendritic shaft (GO:0043198)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendritic spine (GO:0043197)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: pTarget method	LOCATE	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Sarcolemma (GO:0042383)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	T-tubule (GO:0030315)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Intercalated disc (GO:0014704)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.995

Q9P2F8

(UniProtKB/Swiss-Prot/P) Details

Signal-induced proliferation-associated 1-like protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
N/A	Cellular component (GO:0005575)	0.3	Unknown: no biological data available	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.94	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nuclear membrane (GO:0031965)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear body (GO:0016604)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.995

Q969F2

(UniProtKB/Swiss-Prot/P) Details

Protein naked cuticle homolog 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.973	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.973	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.973	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.96	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Exocytic vesicle (GO:0070382)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell periphery (GO:0071944)	0.998	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Experimental: inferred from direct assay	GO	PubMed
Membrane	Lateral plasma membrane (GO:0016328)	0.998	Experimental: inferred from direct assay	GO	PubMed
Membrane	Basolateral plasma membrane (GO:0016323)	0.998	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.995

Q9NSK0

(UniProtKB/Swiss-Prot/P) Details

Kinesin light chain 4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.994	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.994	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.994	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Kinesin complex (GO:0005871)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Microtubule (GO:0005874)	0.994	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

0.995

P04629

(UniProtKB/Swiss-Prot/P) Details

High affinity nerve growth factor receptor

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Neuronal cell body (GO:0043025)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.897	Unknown: unspecified method	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.897	Unknown: unspecified method	The Human Protein Atlas	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.7	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.994	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.994	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	0.994	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Late endosome membrane (GO:0031902)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Early endosome membrane (GO:0031901)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Late endosome (GO:0005770)	0.994	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Lysosome (GO:0005764)	0.897	Predicted: pTarget method	LOCATE	PubMed
Membrane	Dendrite (GO:0030425)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Axon (GO:0030424)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Receptor complex (GO:0043235)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.995

Q8IVT5

(UniProtKB/Swiss-Prot/P) Details

Kinase suppressor of Ras 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.79	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.79	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.982	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.982	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.982	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.86	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Ruffle membrane (GO:0032587)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.51	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.995

Q16526

(UniProtKB/Swiss-Prot/P) Details

Cryptochrome-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.86	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear membrane (GO:0031965)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.995

Q5T0W9

(UniProtKB/Swiss-Prot/P) Details

Protein FAM83B

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.8	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.973	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.973	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.973	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.995

P48637

(UniProtKB/Swiss-Prot/P) Details

Glutathione synthetase

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.981	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.981	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.981	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.981	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.995

Q04912

(UniProtKB/Swiss-Prot/P) Details

Macrophage-stimulating protein receptor

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	0.979	Unknown: HDA	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.971	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Vacuole (GO:0005773)	0.971	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Lysosome (GO:0005764)	0.971	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Stress fiber (GO:0001725)	0.971	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.979	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.979	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.979	Experimental: experimental	Organelle	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	0.979	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

HPRD, BioGRID

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

0.994

O00459

(UniProtKB/Swiss-Prot/P) Details

Phosphatidylinositol 3-kinase regulatory subunit beta

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.937	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.937	Unknown: traceable author statement	GO	PubMed
Cytosol	Phosphatidylinositol 3-kinase complex (GO:0005942)	0.937	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.973	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.973	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.973	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.994

O43143

(UniProtKB/Swiss-Prot/P) Details

Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.94	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Ribonucleoprotein complex (GO:0030529)	0.94	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	U2-type post-mRNA release spliceosomal complex (GO:0071008)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	U12-type spliceosomal complex (GO:0005689)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.994

Q9Y4F5

(UniProtKB/Swiss-Prot/P) Details

Centrosomal protein of 170 kDa protein B

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.994	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.994	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Centrosome (GO:0005813)	0.994	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Microtubule (GO:0005874)	0.994	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.994

Q92934

(UniProtKB/Swiss-Prot/P) Details

Bcl2-associated agonist of cell death

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.96	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	0.96	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial outer membrane (GO:0005741)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	eSLDB	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

0.994

Q9P2M7

(UniProtKB/Swiss-Prot/P) Details

Cingulin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.958	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.958	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Myosin complex (GO:0016459)	0.958	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Cell junction (GO:0030054)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Tight junction (GO:0005923)	1	Unknown: non-traceable author statement	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.994

Q68DZ5

(UniProtKB/TrEmbl/P) Details

cDNA FLJ58316, highly similar to Beta-arrestin-2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.96	Experimental: experimental	eSLDB	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.994

A0JNW5

(UniProtKB/Swiss-Prot/P) Details

UHRF1-binding protein 1-like

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.96	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Secretory-pathway	GARP complex (GO:0000938)	0.96	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.994

Q86W92

(UniProtKB/Swiss-Prot/P) Details

Liprin-beta-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.987	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.987	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytosol (GO:0005829)	0.987	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.987	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Plasma membrane (GO:0005886)	0.98	Unknown: non-traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.98	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	0.98	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Focal adhesion (GO:0005925)	0.98	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

0.994

Q9ULR3

(UniProtKB/Swiss-Prot/P) Details

Protein phosphatase 1H

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.94	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.992	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.994

O60573

(UniProtKB/Swiss-Prot/P) Details

Eukaryotic translation initiation factor 4E type 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.992	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	0.992	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	MRNA cap binding complex (GO:0005845)	0.992	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.993

Q5U0Q1

(UniProtKB/TrEmbl/P) Details

Ras-GTPase-activating protein SH3-domain-binding protein, isoform CRA_a

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.96	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: experimental	eSLDB	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	eSLDB	PubMed
Cytosol	Vesicle (GO:0031982)	0.96	Experimental: experimental	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.993

Q99469

(UniProtKB/Swiss-Prot/P) Details

SH3 and cysteine-rich domain-containing protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.958	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.958	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.958	Unknown: non-traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.79	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.79	Unknown: unspecified method	The Human Protein Atlas	PubMed
Membrane	Plasma membrane (GO:0005886)	0.853	Unknown: unspecified method	The Human Protein Atlas	PubMed
Membrane	T-tubule (GO:0030315)	0.853	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Extrinsic to internal side of plasma membrane (GO:0031234)	0.853	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.993

Q5JSL3

(UniProtKB/Swiss-Prot/P) Details

Dedicator of cytokinesis protein 11

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.937	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.937	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.937	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleolus (GO:0005730)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear membrane (GO:0031965)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.993

Q86TI0

(UniProtKB/Swiss-Prot/P) Details

TBC1 domain family member 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endomembrane system (GO:0012505)	0.937	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Intracellular (GO:0005622)	0.937	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.937	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.987	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.987	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.987	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.987	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	0.987	Unknown: unspecified method	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.993

P57103

(UniProtKB/Swiss-Prot/P) Details

Sodium/calcium exchanger 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Perikaryon (GO:0043204)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Sarcoplasm (GO:0016528)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.931	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial outer membrane (GO:0005741)	0.7	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.91	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.91	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Microtubule (GO:0005874)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendritic spine (GO:0043197)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: pTarget method	LOCATE	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Sarcolemma (GO:0042383)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Intrinsic to plasma membrane (GO:0031226)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Neuromuscular junction (GO:0031594)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.993

Q96KP6

(UniProtKB/Swiss-Prot/P) Details

TNFAIP3-interacting protein 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.981	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.981	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.981	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.981	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.993

Q96AY4

(UniProtKB/Swiss-Prot/P) Details

Tetratricopeptide repeat protein 28

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Midbody (GO:0030496)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.897	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleolus (GO:0005730)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Spindle pole (GO:0000922)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	0.897	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.993

Q86WV8

(UniProtKB/TrEmbl/P) Details

Hamartin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.988	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.988	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytosol (GO:0005829)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.993

E9PMT2

(UniProtKB/TrEmbl/P) Details

LIM domain only protein 7

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.993

O43896

(UniProtKB/Swiss-Prot/P) Details

Kinesin-like protein KIF1C

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.987	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.902	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.902	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.987	Experimental: experimental	Organelle	PubMed
Cytosol	Kinesin complex (GO:0005871)	0.987	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Microtubule (GO:0005874)	0.987	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

0.992

O75494

(UniProtKB/Swiss-Prot/P) Details

Serine/arginine-rich splicing factor 10

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.902	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.902	Unknown: non-traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Unknown: inferred by curator	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.992

P10398

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein kinase A-Raf

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
N/A	Cellular component (GO:0005575)	0.3	Unknown: no biological data available	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.91	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.91	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Fibrillar center (GO:0001650)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.992

P52788

(UniProtKB/Swiss-Prot/P) Details

Spermine synthase

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.971	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	0.971	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.971	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear body (GO:0016604)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.971	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.992

Q8TF72

(UniProtKB/Swiss-Prot/P) Details

Protein Shroom3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.956	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.956	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.956	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Microtubule (GO:0005874)	0.956	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Apical junction complex (GO:0043296)	0.973	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Apical plasma membrane (GO:0016324)	0.973	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Adherens junction (GO:0005912)	0.973	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.992

P57078

(UniProtKB/Swiss-Prot/P) Details

Receptor-interacting serine/threonine-protein kinase 4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.973	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.973	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.973	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.991

Q96S53

(UniProtKB/Swiss-Prot/P) Details

Dual specificity testis-specific protein kinase 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.91	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.91	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

HPRD, BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.991

Q9NSI8

(UniProtKB/Swiss-Prot/P) Details

SAM domain-containing protein SAMSN-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.937	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.937	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.937	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: inferred from direct assay	GO	PubMed
Membrane	Ruffle (GO:0001726)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.972	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.972	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.991

Q15569

(UniProtKB/Swiss-Prot/P) Details

Dual specificity testis-specific protein kinase 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.937	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.937	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.937	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.7	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.991

P47974

(UniProtKB/Swiss-Prot/P) Details

mRNA decay activator protein ZFP36L2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.91	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.91	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Predicted: PAML algorithm	PA-GOSUB	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.99

P68431

(UniProtKB/Swiss-Prot/P) Details

Histone H3.1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear chromosome (GO:0000228)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleosome (GO:0000786)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nuclear nucleosome (GO:0000788)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.86	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.86	Experimental: experimental	MatrixDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.99

Q8N4E4

(UniProtKB/Swiss-Prot/P) Details

Phosducin-like protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.973	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.973	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.973	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.99

Q9HAP2

(UniProtKB/Swiss-Prot/P) Details

MLX-interacting protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Mitochondrial outer membrane (GO:0005741)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

HPRD, BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.99

Q9Y4L5

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase RNF115

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.91	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.91	Predicted: inferred from sequence or structural similarity	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleolus (GO:0005730)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.99

Q7Z6J6

(UniProtKB/Swiss-Prot/P) Details

FERM domain-containing protein 5

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.937	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.3	Unknown: unspecified method	The Human Protein Atlas	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.937	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Centrosome (GO:0005813)	0.937	Unknown: unspecified method	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.972	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Adherens junction (GO:0005912)	0.972	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.989

Q9HCD6

(UniProtKB/Swiss-Prot/P) Details

Protein TANC2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: PAML algorithm	PA-GOSUB	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.989

Q9UHD1

(UniProtKB/Swiss-Prot/P) Details

Cysteine and histidine-rich domain-containing protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
N/A	Cellular component (GO:0005575)	0.3	Unknown: no biological data available	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: pTarget method	LOCATE	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.989

P16104

(UniProtKB/Swiss-Prot/P) Details

Histone H2AX

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Male germ cell nucleus (GO:0001673)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Centrosome (GO:0005813)	0.86	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Chromosome (GO:0005694)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Site of double-strand break (GO:0035861)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Condensed nuclear chromosome (GO:0000794)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nuclear chromatin (GO:0000790)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Replication fork (GO:0005657)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleosome (GO:0000786)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Chromosome, telomeric region (GO:0000781)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	XY body (GO:0001741)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.86	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.989

O43299

(UniProtKB/Swiss-Prot/P) Details

AP-5 complex subunit zeta-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.8	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Integral to membrane (GO:0016021)	0.853	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	AP-type membrane coat adaptor complex (GO:0030119)	0.853	Unknown: non-traceable author statement	GO	PubMed
Membrane	AP-5 adaptor complex (GO:0044599)	0.853	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

0.989

Q9Y2J2

(UniProtKB/Swiss-Prot/P) Details

Band 4.1-like protein 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.937	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.937	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.937	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Postsynaptic density (GO:0014069)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Juxtaparanode region of axon (GO:0044224)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Paranode region of axon (GO:0033270)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Axolemma (GO:0030673)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Cell-cell junction (GO:0005911)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

0.989

Q63HR2

(UniProtKB/Swiss-Prot/P) Details

Tensin-2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular (GO:0005622)	0.937	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.937	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.937	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.972	Experimental: experimental	Human Proteinpedia	PubMed
Membrane	Focal adhesion (GO:0005925)	0.972	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.988

P30304

(UniProtKB/Swiss-Prot/P) Details

M-phase inducer phosphatase 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.86	Unknown: traceable author statement	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.86	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.987	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.987	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.987	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.987	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

HPRD, BioGRID, DIP, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.988

P46937

(UniProtKB/Swiss-Prot/P) Details

Transcriptional coactivator YAP1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.86	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.86	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleolus (GO:0005730)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.999	Unknown: traceable author statement	GO	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, DIP, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

0.987

Q96F86

(UniProtKB/Swiss-Prot/P) Details

Enhancer of mRNA-decapping protein 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.958	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasmic mRNA processing body (GO:0000932)	0.958	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.958	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

0.987

Q6NZY4

(UniProtKB/Swiss-Prot/P) Details

Zinc finger CCHC domain-containing protein 8

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	TRAMP complex (GO:0031499)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Catalytic step 2 spliceosome (GO:0071013)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.986

I3L2J8

(UniProtKB/TrEmbl/P) Details

Centrosomal protein of 131 kDa

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Microtubule cytoskeleton (GO:0015630)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Intercellular bridge (GO:0045171)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.985

F8WD26

(UniProtKB/TrEmbl/P) Details

LIM domain only protein 7

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.985

A2RU30

(UniProtKB/Swiss-Prot/P) Details

Protein TESPA1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Signalosome (GO:0008180)	0.94	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.984

Q86VQ0

(UniProtKB/Swiss-Prot/P) Details

Lebercilin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.853	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.853	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	0.853	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Cilium (GO:0005929)	0.8	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.984

Q9UK53

(UniProtKB/Swiss-Prot/P) Details

Inhibitor of growth protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.997	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.997	Unknown: non-traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.997	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	0.997	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.997	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.984

O15297

(UniProtKB/Swiss-Prot/P) Details

Protein phosphatase 1D

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.992	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.984

Q2TAL5

(UniProtKB/Swiss-Prot/P) Details

Smoothelin-like protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.91	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: pTarget method	LOCATE	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.984

Q96TC7

(UniProtKB/Swiss-Prot/P) Details

Regulator of microtubule dynamics protein 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.853	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.992	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial outer membrane (GO:0005741)	0.992	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Spindle pole (GO:0000922)	0.853	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Microtubule (GO:0005874)	0.853	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.79	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

0.983

P01100

(UniProtKB/Swiss-Prot/P) Details

Proto-oncogene c-Fos

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	AP1 complex (GO:0035976)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Protein-DNA complex (GO:0032993)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Neuron projection (GO:0043005)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.51	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.983

A0A0A0MR98

(UniProtKB/TrEmbl/P) Details

NAD kinase

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.983

P02751

(UniProtKB/Swiss-Prot/P) Details

Fibronectin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.971	Predicted: SVM decision tree	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum lumen (GO:0005788)	0.971	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum-Golgi intermediate compartment (GO:0005793)	0.971	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Lysosome (GO:0005764)	0.79	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Platelet alpha granule lumen (GO:0031093)	0.971	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	1	Unknown: non-traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	1	Predicted: pTarget method	LOCATE	PubMed
Extracellular	Extracellular region (GO:0005576)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Fibrinogen complex (GO:0005577)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Blood microparticle (GO:0072562)	1	Unknown: HDA	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	1	Experimental: experimental	MatrixDB	PubMed
Extracellular	Basement membrane (GO:0005604)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Membrane (GO:0016020)	0.86	Experimental: experimental	MatrixDB	PubMed
Membrane	Apical plasma membrane (GO:0016324)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.79	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.982

Q8IWE0

(UniProtKB/TrEmbl/P) Details

Calcium/calmodulin-dependent protein kinase II alpha

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.982	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.982	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.982	Predicted: pTarget method	LOCATE	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.982

Q13748

(UniProtKB/Swiss-Prot/P) Details

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.982	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.982	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.982	Experimental: experimental	Organelle	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.981

Q9Y6M7

(UniProtKB/Swiss-Prot/P) Details

Sodium bicarbonate cotransporter 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.86	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.79	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.79	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Stereocilium (GO:0032420)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Unknown: non-traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Apical plasma membrane (GO:0016324)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Basolateral plasma membrane (GO:0016323)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Synapse (GO:0045202)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

0.98

Q13111

(UniProtKB/Swiss-Prot/P) Details

Chromatin assembly factor 1 subunit A

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	CAF-1 complex (GO:0033186)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Chromosome (GO:0005694)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nuclear chromatin (GO:0000790)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.98

P42285

(UniProtKB/Swiss-Prot/P) Details

Exosome RNA helicase MTR4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Exosome (RNase complex) (GO:0000178)	0.8	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nuclear exosome (RNase complex) (GO:0000176)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	TRAMP complex (GO:0031499)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Catalytic step 2 spliceosome (GO:0071013)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.98

P19484

(UniProtKB/Swiss-Prot/P) Details

Transcription factor EB

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.8	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.98

Q9GZP4

(UniProtKB/Swiss-Prot/P) Details

PITH domain-containing protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.973	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.973	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.973	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.98

P20823

(UniProtKB/Swiss-Prot/P) Details

Hepatocyte nuclear factor 1-alpha

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.8	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.999	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.979

P21127

(UniProtKB/Swiss-Prot/P) Details

Cyclin-dependent kinase 11B

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.79	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.79	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

HPRD, BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.979

P30291

(UniProtKB/Swiss-Prot/P) Details

Wee1-like protein kinase

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.79	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.79	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.979

Q53ET0

(UniProtKB/Swiss-Prot/P) Details

CREB-regulated transcription coactivator 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.79	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.79	Unknown: HDA	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.979

O60825

(UniProtKB/Swiss-Prot/P) Details

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.79	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.79	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.998	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.979

Q86ST5

(UniProtKB/TrEmbl/P) Details

AGAP3 protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.91	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: pTarget method	LOCATE	PubMed
Membrane	Plasma membrane (GO:0005886)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.978

A0A0C4DFX9

(UniProtKB/TrEmbl/P) Details

Negative elongation factor A

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear body (GO:0016604)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.978

Q5HYF7

(UniProtKB/TrEmbl/P) Details

Tuberin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.978

Q9BY89

(UniProtKB/Swiss-Prot/P) Details

Uncharacterized protein KIAA1671

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.978

Q9H6H4

(UniProtKB/Swiss-Prot/P) Details

Receptor expression-enhancing protein 4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.86	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.86	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Microtubule (GO:0005874)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.79	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.977

P17181

(UniProtKB/Swiss-Prot/P) Details

Interferon alpha/beta receptor 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.86	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Late endosome (GO:0005770)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Lysosome (GO:0005764)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.994	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.994	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.994	Experimental: experimental	Organelle	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	0.994	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.977

Q15032

(UniProtKB/Swiss-Prot/P) Details

R3H domain-containing protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.982	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.982	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.982	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.977

H7BXY1

(UniProtKB/TrEmbl/P) Details

Regulator of G-protein signalling 3, isoform CRA_i

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.977

A0A0A0MRY0

(UniProtKB/TrEmbl/P) Details

TBC1 domain family member 22A

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.977

P05107

(UniProtKB/Swiss-Prot/P) Details

Integrin beta-2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Secretory-pathway	Tertiary granule membrane (GO:0070821)	0.3	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Membrane (GO:0016020)	1	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	External side of plasma membrane (GO:0009897)	1	Unknown: non-traceable author statement	GO	PubMed
Membrane	Integrin complex (GO:0008305)	1	Unknown: non-traceable author statement	GO	PubMed
Membrane	Receptor complex (GO:0043235)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.79	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.977

O15151

(UniProtKB/Swiss-Prot/P) Details

Protein Mdm4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.977

J3KN01

(UniProtKB/TrEmbl/P) Details

Afadin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Cell junction (GO:0030054)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.976

P42695

(UniProtKB/Swiss-Prot/P) Details

Condensin-2 complex subunit D3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear centromeric heterochromatin (GO:0031618)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Condensed chromosome, centromeric region (GO:0000779)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nuclear condensin complex (GO:0000799)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.976

O96013

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein kinase PAK 4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.3	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.98	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Cell junction (GO:0030054)	0.98	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Focal adhesion (GO:0005925)	0.98	Unknown: HDA	GO	PubMed
Membrane	Cell-cell adherens junction (GO:0005913)	0.98	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

0.975

P08069

(UniProtKB/Swiss-Prot/P) Details

Insulin-like growth factor 1 receptor

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.86	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.86	Unknown: unspecified method	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: pTarget method	LOCATE	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Alphav-beta3 integrin-IGF-1-IGF1R complex (GO:0035867)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Unknown: inferred by curator	GO	PubMed
Membrane	Receptor complex (GO:0043235)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.975

J3QSZ5

(UniProtKB/TrEmbl/P) Details

Protein SON

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.91	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.975

Q6R327

(UniProtKB/Swiss-Prot/P) Details

Rapamycin-insensitive companion of mTOR

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.86	Unknown: traceable author statement	GO	PubMed
Cytosol	TORC2 complex (GO:0031932)	0.86	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

0.974

P07359

(UniProtKB/Swiss-Prot/P) Details

Platelet glycoprotein Ib alpha chain

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	1	Unknown: HDA	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.79	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Anchored to external side of plasma membrane (GO:0031362)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.79	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.974

Q8TBZ3

(UniProtKB/Swiss-Prot/P) Details

WD repeat-containing protein 20

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.91	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.79	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.974

P55851

(UniProtKB/Swiss-Prot/P) Details

Mitochondrial uncoupling protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.94	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.94	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Organelle inner membrane (GO:0019866)	0.8	Experimental: experimental	Organelle	PubMed

Interaction Source Database:

HPRD, BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.973

Q13972

(UniProtKB/Swiss-Prot/P) Details

Ras-specific guanine nucleotide-releasing factor 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.91	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.91	Predicted: inferred from sequence or structural similarity	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Growth cone (GO:0030426)	0.971	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Neuron projection (GO:0043005)	0.971	Unknown: non-traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.971	Unknown: non-traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.971	Experimental: experimental	Organelle	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.972

E9PFI7

(UniProtKB/TrEmbl/P) Details

Poly [ADP-ribose] polymerase

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Flemming body (GO:0090543)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Cell junction (GO:0030054)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.971

Q9UQ35

(UniProtKB/Swiss-Prot/P) Details

Serine/arginine repetitive matrix protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Cajal body (GO:0015030)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	U2-type catalytic step 2 spliceosome (GO:0071007)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Catalytic step 2 spliceosome (GO:0071013)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

0.97

Q9NU19

(UniProtKB/Swiss-Prot/P) Details

TBC1 domain family member 22B

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endomembrane system (GO:0012505)	0.937	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Intracellular (GO:0005622)	0.937	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.937	Unknown: unspecified method	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.3	Unknown: unspecified method	The Human Protein Atlas	PubMed
Membrane	Integral to membrane (GO:0016021)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.97

A0A0C4DFW2

(UniProtKB/TrEmbl/P) Details

Inhibitor of growth protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.97

O15063

(UniProtKB/Swiss-Prot/P) Details

Uncharacterized protein KIAA0355

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.8	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.97

Q53GA5

(UniProtKB/TrEmbl/P) Details

Cellular tumor antigen p53

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.8	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: pTarget method	LOCATE	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.969

J3KNE7

(UniProtKB/TrEmbl/P) Details

Tumor protein D53

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Cell junction (GO:0030054)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.967

Q96II5

(UniProtKB/TrEmbl/P) Details

ARAF protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Fibrillar center (GO:0001650)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.967

E9PKC0

(UniProtKB/TrEmbl/P) Details

Pleckstrin homology domain-containing family A member 7

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Cell junction (GO:0030054)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.967

B7Z3H4

(UniProtKB/TrEmbl/P) Details

Beta-transducin repeat containing isoform 4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Plasma membrane (GO:0005886)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.967

F6VUX8

(UniProtKB/TrEmbl/P) Details

Centromere protein J

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Centrosome (GO:0005813)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Plasma membrane (GO:0005886)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.967

H0Y413

(UniProtKB/TrEmbl/P) Details

Prickle planar cell polarity protein 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Centrosome (GO:0005813)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Plasma membrane (GO:0005886)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.967

Q8N236

(UniProtKB/TrEmbl/P) Details

cDNA FLJ34968 fis, clone NTONG2004844, highly similar to P116 RHO-INTERACTING PROTEIN

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.91	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.967

Q6ZRV7

(UniProtKB/TrEmbl/P) Details

cDNA FLJ46057 fis, clone T1ESE2000609, highly similar to SON protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.91	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.965

Q70EL4

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin carboxyl-terminal hydrolase 43

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	0.981	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.981	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.981	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.981	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.964

Q32NF0

(UniProtKB/TrEmbl/P) Details

TSC1 protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.94	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.94	Predicted: pTarget method	LOCATE	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.964

G8JLH2

(UniProtKB/TrEmbl/P) Details

M-phase inducer phosphatase 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: pTarget method	LOCATE	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.964

P31040

(UniProtKB/Swiss-Prot/P) Details

Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Myelin sheath (GO:0043209)	0.958	Unknown: inferred from electronic annotation	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: pTarget method	LOCATE	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Mitochondrion	Mitochondrial respiratory chain complex II (GO:0005749)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	0.8	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.958	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane succinate dehydrogenase complex (GO:0045282)	0.958	Predicted: inferred from biological aspect of ancestor	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.963

E9PFN4

(UniProtKB/TrEmbl/P) Details

Anion exchange protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Focal adhesion (GO:0005925)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.96

A0A2R8Y8E0

(UniProtKB/TrEmbl/P) Details

Serine/threonine-protein kinase B-raf

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.96

M0QY76

(UniProtKB/TrEmbl/P) Details

Zinc finger protein 36, C3H type, homolog (Mouse), isoform CRA_a

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Intermediate filament cytoskeleton (GO:0045111)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.96

A0A0A0MTE2

(UniProtKB/TrEmbl/P) Details

LIM domain only protein 7

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.959

O14829

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein phosphatase with EF-hands 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.937	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.937	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.937	Unknown: traceable author statement	GO	PubMed
Extracellular	Intercellular bridge (GO:0045171)	0.3	Unknown: unspecified method	The Human Protein Atlas	PubMed
Membrane	Plasma membrane (GO:0005886)	0.3	Unknown: unspecified method	The Human Protein Atlas	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.959

Q70EL1

(UniProtKB/Swiss-Prot/P) Details

Inactive ubiquitin carboxyl-terminal hydrolase 54

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: pTarget method	LOCATE	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.958

Q9C0I1

(UniProtKB/Swiss-Prot/P) Details

Myotubularin-related protein 12

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.958	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.958	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.958	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.958

E5RH50

(UniProtKB/TrEmbl/P) Details

La-related protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.958

E5RHK4

(UniProtKB/TrEmbl/P) Details

La-related protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.958

B0QYI1

(UniProtKB/TrEmbl/P) Details

TBC1 domain family member 22A

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.956

Q7Z401

(UniProtKB/Swiss-Prot/P) Details

C-myc promoter-binding protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.3	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleolus (GO:0005730)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Integral to membrane (GO:0016021)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

0.956

O14654

(UniProtKB/Swiss-Prot/P) Details

Insulin receptor substrate 4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.7	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.94	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.94	Experimental: experimental	Organelle	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.954

Q14654

(UniProtKB/Swiss-Prot/P) Details

ATP-sensitive inward rectifier potassium channel 11

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Myelin sheath (GO:0043209)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Neuronal cell body (GO:0043025)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nuclear envelope (GO:0005635)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Acrosomal vesicle (GO:0001669)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Cell body fiber (GO:0070852)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Axolemma (GO:0030673)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	ATP-sensitive potassium channel complex (GO:0008282)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	T-tubule (GO:0030315)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Intercalated disc (GO:0014704)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.952

P30307

(UniProtKB/Swiss-Prot/P) Details

M-phase inducer phosphatase 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.51	Unknown: traceable author statement	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.999	Unknown: traceable author statement	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

HPRD, BioGRID, DIP, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

0.952

P61587

(UniProtKB/Swiss-Prot/P) Details

Rho-related GTP-binding protein RhoE

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.958	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.958	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.958	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.958	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.958	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Focal adhesion (GO:0005925)	0.958	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.946

Q59FK4

(UniProtKB/TrEmbl/P) Details

Tyrosine-protein kinase

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: PAML algorithm	PA-GOSUB	PubMed

Interaction Source Database:

HPRD, BioGRID

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

0.946

Q86U11

(UniProtKB/TrEmbl/P) Details

Full-length cDNA clone CS0DE006YM09 of Placenta of Homo sapiens

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: pTarget method	LOCATE	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.946

A4D7V5

(UniProtKB/TrEmbl/P) Details

Activating transcription factor 2 splice variant ATF2-var12

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: pTarget method	LOCATE	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.944

Q6I9V6

(UniProtKB/TrEmbl/P) Details

CDKN1B protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.8	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: experimental	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.944

Q59EM5

(UniProtKB/TrEmbl/P) Details

Arrestin beta 2 isoform 1 variant

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.8	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: experimental	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.944

C9JVE2

(UniProtKB/TrEmbl/P) Details

DCN1-like protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.944

A0A075B7B5

(UniProtKB/TrEmbl/P) Details

SLIT-ROBO Rho GTPase-activating protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.944

B7ZM87

(UniProtKB/TrEmbl/P) Details

SLIT-ROBO Rho GTPase-activating protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.944

E9PFX5

(UniProtKB/TrEmbl/P) Details

Peroxisome proliferator-activated receptor gamma

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.944

E9PFR9

(UniProtKB/TrEmbl/P) Details

Spermatogenesis-associated protein 13

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.942

Q9UQ84

(UniProtKB/Swiss-Prot/P) Details

Exonuclease 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Plasma membrane (GO:0005886)	0.8	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

0.942

O95696

(UniProtKB/Swiss-Prot/P) Details

Bromodomain-containing protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Perikaryon (GO:0043204)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	MOZ/MORF histone acetyltransferase complex (GO:0070776)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Dendrite (GO:0030425)	0.3	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.94

P13612

(UniProtKB/Swiss-Prot/P) Details

Integrin alpha-4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Neuronal cell body (GO:0043025)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Growth cone (GO:0030426)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Membrane (GO:0016020)	1	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: pTarget method	LOCATE	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.51	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.94

Q5ST81

(UniProtKB/TrEmbl/P) Details

Tubulin beta chain

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.94

D4Q8H0

(UniProtKB/TrEmbl/P) Details

Mitogen-activated protein kinase kinase kinase MLT

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.937

Q8NFH8

(UniProtKB/Swiss-Prot/P) Details

RalBP1-associated Eps domain-containing protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.937	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.937	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.937	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.933

P16144

(UniProtKB/Swiss-Prot/P) Details

Integrin beta-4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Cell leading edge (GO:0031252)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell surface (GO:0009986)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: pTarget method	LOCATE	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Integrin complex (GO:0008305)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Receptor complex (GO:0043235)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Hemidesmosome (GO:0030056)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.3	Unknown: HDA	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.931

P05412

(UniProtKB/Swiss-Prot/P) Details

Transcription factor AP-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Transcriptional repressor complex (GO:0017053)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	AP1 complex (GO:0035976)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Chromosome (GO:0005694)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nuclear chromosome (GO:0000228)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nuclear euchromatin (GO:0005719)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.931

Q14469

(UniProtKB/Swiss-Prot/P) Details

Transcription factor HES-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.999	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.93

P84103

(UniProtKB/Swiss-Prot/P) Details

Serine/arginine-rich splicing factor 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.998	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.998	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

0.93

P85037

(UniProtKB/Swiss-Prot/P) Details

Forkhead box protein K1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.997	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.997	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Fibrillar center (GO:0001650)	0.997	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.997	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.997	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.928

E5RGS2

(UniProtKB/TrEmbl/P) Details

Receptor expression-enhancing protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.928

Q15884

(UniProtKB/Swiss-Prot/P) Details

Protein FAM189A2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
N/A	Cellular component (GO:0005575)	0.3	Unknown: no biological data available	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.3	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.926

B4DIG0

(UniProtKB/TrEmbl/P) Details

cDNA FLJ53333, highly similar to M-phase inducer phosphatase 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.926

J3KPJ3

(UniProtKB/TrEmbl/P) Details

Calcium/calmodulin-dependent protein kinase kinase 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.922

A8MQ02

(UniProtKB/TrEmbl/P) Details

Afadin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Cell junction (GO:0030054)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.919

Q9BST9

(UniProtKB/Swiss-Prot/P) Details

Rhotekin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
N/A	Cellular component (GO:0005575)	0.3	Unknown: no biological data available	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.3	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.917

P55317

(UniProtKB/Swiss-Prot/P) Details

Hepatocyte nuclear factor 3-alpha

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Fibrillar center (GO:0001650)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Fibrillar center (GO:0001650)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Microvillus (GO:0005902)	0.3	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.916

Q05DE3

(UniProtKB/TrEmbl/P) Details

LUZP1 protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: experimental	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.914

Q8NI37

(UniProtKB/Swiss-Prot/P) Details

Protein phosphatase PTC7 homolog

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.91	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.913

Q6PJ22

(UniProtKB/TrEmbl/P) Details

FLJ13052 protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.91

E7EVJ5

(UniProtKB/TrEmbl/P) Details

Cytoplasmic FMR1-interacting protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Plasma membrane (GO:0005886)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.91

Q6P164

(UniProtKB/TrEmbl/P) Details

Kinesin-like protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.91	Predicted: pTarget method	LOCATE	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.91

Q7RTQ2

(UniProtKB/TrEmbl/P) Details

Kinesin light chain 1E

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.91	Predicted: pTarget method	LOCATE	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.91

Q7LDD5

(UniProtKB/TrEmbl/P) Details

Calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha, isoform CRA_a

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.91	Predicted: pTarget method	LOCATE	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.91

Q6PK50

(UniProtKB/TrEmbl/P) Details

HSP90AB1 protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.91	Predicted: pTarget method	LOCATE	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.91

Q9BRL4

(UniProtKB/TrEmbl/P) Details

PCTK1 protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.91	Predicted: PAML algorithm	PA-GOSUB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.91

Q59FE1

(UniProtKB/TrEmbl/P) Details

Eukaryotic translation initiation factor 4E member 2 variant

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.91	Predicted: PAML algorithm	PA-GOSUB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.902

A0A0A0MRG2

(UniProtKB/TrEmbl/P) Details

Amyloid-beta A4 protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Integral to membrane (GO:0016021)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.902

P35610

(UniProtKB/Swiss-Prot/P) Details

Sterol O-acyltransferase 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.958	Experimental: inferred from direct assay	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.958	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.958	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.902

O00257

(UniProtKB/Swiss-Prot/P) Details

E3 SUMO-protein ligase CBX4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	PcG protein complex (GO:0031519)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	PRC1 complex (GO:0035102)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.902

P01106

(UniProtKB/Swiss-Prot/P) Details

Myc proto-oncogene protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear chromatin (GO:0000790)	1	Experimental: inferred from mutant phenotype	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.902

Q9BZJ0

(UniProtKB/Swiss-Prot/P) Details

Crooked neck-like protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Prp19 complex (GO:0000974)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Spliceosomal complex (GO:0005681)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Post-mRNA release spliceosomal complex (GO:0071014)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Precatalytic spliceosome (GO:0071011)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	U2-type catalytic step 2 spliceosome (GO:0071007)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Catalytic step 2 spliceosome (GO:0071013)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.901

P18583

(UniProtKB/Swiss-Prot/P) Details

Protein SON

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.9

Q6PJG9

(UniProtKB/Swiss-Prot/P) Details

Leucine-rich repeat and fibronectin type-III domain-containing protein 4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.996	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.996	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.996	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.996	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.994	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.994	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.994	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.994	Predicted: PAML algorithm	PA-GOSUB	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.9

Q9P244

(UniProtKB/Swiss-Prot/P) Details

Leucine-rich repeat and fibronectin type III domain-containing protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.996	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.996	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.996	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.996	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.994	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.994	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.994	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.994	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Cell junction (GO:0030054)	0.994	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.899

Q9Y2K5

(UniProtKB/Swiss-Prot/P) Details

R3H domain-containing protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	0.996	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.898

E9PNK6

(UniProtKB/TrEmbl/P) Details

Tumor protein D53

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Cell junction (GO:0030054)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.898

E9PPQ1

(UniProtKB/TrEmbl/P) Details

Tumor protein D53

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Cell junction (GO:0030054)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.896

Q6MZF4

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein DKFZp686F219

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Lysosome (GO:0005764)	0.7	Predicted: pTarget method	LOCATE	PubMed
Extracellular	Extracellular region (GO:0005576)	0.7	Predicted: pTarget method	LOCATE	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.896

Q6MZM7

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein DKFZp686O12165

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Lysosome (GO:0005764)	0.7	Predicted: pTarget method	LOCATE	PubMed
Extracellular	Extracellular region (GO:0005576)	0.7	Predicted: pTarget method	LOCATE	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.894

Q9Y2K2

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein kinase SIK3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.891

Q6ICG6

(UniProtKB/Swiss-Prot/P) Details

Uncharacterized protein KIAA0930

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Mitochondrion	Mitochondrion (GO:0005739)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nuclear membrane (GO:0031965)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.889

Q96C95

(UniProtKB/TrEmbl/P) Details

MLLT4 protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.889

Q9H2L9

(UniProtKB/TrEmbl/P) Details

AD034

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.889

Q6ZR29

(UniProtKB/TrEmbl/P) Details

cDNA FLJ46702 fis, clone TRACH3014183

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.889

Q05CP0

(UniProtKB/TrEmbl/P) Details

ANKS1A protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: pTarget method	LOCATE	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.889

Q6ZP53

(UniProtKB/TrEmbl/P) Details

cDNA FLJ26493 fis, clone KDN06317, highly similar to Ras-GTPase-activating protein binding protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.886

Q5JRI1

(UniProtKB/TrEmbl/P) Details

Serine/arginine-rich-splicing factor 10

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	0.982	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.982	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.982	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.882

H3BRW9

(UniProtKB/TrEmbl/P) Details

Dual-specificity mitogen-activated protein kinase kinase 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Plasma membrane (GO:0005886)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.882

I3L4C2

(UniProtKB/TrEmbl/P) Details

Brain-specific angiogenesis inhibitor 1-associated protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Plasma membrane (GO:0005886)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.882

G3V2R1

(UniProtKB/TrEmbl/P) Details

Protein Smaug homolog 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Cell junction (GO:0030054)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.878

Q9P0K1

(UniProtKB/Swiss-Prot/P) Details

Disintegrin and metalloproteinase domain-containing protein 22

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Axon (GO:0030424)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

HPRD, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

0.876

Q9UPR5

(UniProtKB/Swiss-Prot/P) Details

Sodium/calcium exchanger 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Perikaryon (GO:0043204)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendritic spine (GO:0043197)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.994	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.994	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.994	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	0.994	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Basolateral plasma membrane (GO:0016323)	0.994	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.876

Q8TBC3

(UniProtKB/Swiss-Prot/P) Details

SH3KBP1-binding protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Lysosome (GO:0005764)	0.79	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.866

B0QYS6

(UniProtKB/TrEmbl/P) Details

Transcription factor EB

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.866

P49685

(UniProtKB/Swiss-Prot/P) Details

G-protein coupled receptor 15

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Endosome (GO:0005768)	0.8	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.998	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	0.998	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.848

E9PG40

(UniProtKB/TrEmbl/P) Details

Amyloid-beta A4 protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.848

E3W994

(UniProtKB/TrEmbl/P) Details

CLIP-associating protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.848

E7ERI8

(UniProtKB/TrEmbl/P) Details

CLIP-associating protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.848

E7EW49

(UniProtKB/TrEmbl/P) Details

CLIP-associating protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.848

B8ZZ50

(UniProtKB/TrEmbl/P) Details

Eukaryotic translation initiation factor 4E type 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.848

B8ZZL3

(UniProtKB/TrEmbl/P) Details

Eukaryotic translation initiation factor 4E type 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.848

B9A023

(UniProtKB/TrEmbl/P) Details

Eukaryotic translation initiation factor 4E type 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.847

O14649

(UniProtKB/Swiss-Prot/P) Details

Potassium channel subfamily K member 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Extracellular	Extracellular region (GO:0005576)	0.86	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: pTarget method	LOCATE	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.847

Q96PX8

(UniProtKB/Swiss-Prot/P) Details

SLIT and NTRK-like protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Extracellular	Extracellular region (GO:0005576)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.998	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.998	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Cell junction (GO:0030054)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Synapse (GO:0045202)	0.998	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.837

Q9NPC2

(UniProtKB/Swiss-Prot/P) Details

Potassium channel subfamily K member 9

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Synaptic vesicle (GO:0008021)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.987	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.987	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.987	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	0.987	Predicted: inferred from biological aspect of ancestor	GO	PubMed

Interaction Source Database:

HPRD, BioGRID

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

0.824

P48039

(UniProtKB/Swiss-Prot/P) Details

Melatonin receptor type 1A

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Receptor complex (GO:0043235)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.823

P49286

(UniProtKB/Swiss-Prot/P) Details

Melatonin receptor type 1B

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.998	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Predicted: pTarget method	LOCATE	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	0.998	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.823

Q9H427

(UniProtKB/Swiss-Prot/P) Details

Potassium channel subfamily K member 15

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.994	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.994	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.994	Predicted: pTarget method	LOCATE	PubMed
Membrane	Plasma membrane (GO:0005886)	0.994	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	0.994	Predicted: inferred from biological aspect of ancestor	GO	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.822

A0A0A0MRA8

(UniProtKB/TrEmbl/P) Details

Band 4.1-like protein 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.821

Q86T74

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein DKFZp451O0517

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: pTarget method	LOCATE	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.821

Q05CP8

(UniProtKB/TrEmbl/P) Details

CCDC6 protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: pTarget method	LOCATE	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.821

Q59G93

(UniProtKB/TrEmbl/P) Details

Bromodomain containing protein 1 variant

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: PAML algorithm	PA-GOSUB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.8

B3KT21

(UniProtKB/TrEmbl/P) Details

cDNA FLJ37476 fis, clone BRAWH2012827, highly similar to Homo sapiens BH3 interacting domain death agonist (BID), transcript variant 1, mRNA

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.8	Experimental: experimental	Human Proteinpedia	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.8

M0QZ22

(UniProtKB/TrEmbl/P) Details

Protein Smaug homolog 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.8

A8MYJ1

(UniProtKB/TrEmbl/P) Details

A-kinase anchor protein 13

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.8

H3BMQ0

(UniProtKB/TrEmbl/P) Details

Tuberin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.8

X5D2U8

(UniProtKB/TrEmbl/P) Details

Tuberin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.8

A0A2R8Y5S3

(UniProtKB/TrEmbl/P) Details

Hamartin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.8

B4DGD8

(UniProtKB/TrEmbl/P) Details

GTPase-activating protein and VPS9 domain-containing protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.8

F8W9S7

(UniProtKB/TrEmbl/P) Details

GTPase-activating protein and VPS9 domain-containing protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.8

K7ENA6

(UniProtKB/TrEmbl/P) Details

Beta-arrestin-2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.8

Q5ZPJ1

(UniProtKB/TrEmbl/P) Details

Bax protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.8	Experimental: experimental	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.8

A0A087WZ06

(UniProtKB/TrEmbl/P) Details

Serine/threonine-protein kinase 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intermediate filament cytoskeleton (GO:0045111)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.8

F5GWT4

(UniProtKB/TrEmbl/P) Details

Serine/threonine-protein kinase WNK1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.8

Q8WUK8

(UniProtKB/TrEmbl/P) Details

SH3 and cysteine rich domain

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.8	Experimental: experimental	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.787

E9PFD7

(UniProtKB/TrEmbl/P) Details

Receptor protein-tyrosine kinase

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.787

Q504U8

(UniProtKB/TrEmbl/P) Details

Receptor protein-tyrosine kinase

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.763

Q68DS0

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein DKFZp781N011

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.759

Q96GL9

(UniProtKB/Swiss-Prot/P) Details

Protein FAM163A

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.3	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.748

C9J5X1

(UniProtKB/TrEmbl/P) Details

Tyrosine-protein kinase receptor

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.3	Unknown: unspecified method	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.726

D6RFM5

(UniProtKB/TrEmbl/P) Details

Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.722

Q86V29

(UniProtKB/TrEmbl/P) Details

Wee1-like protein kinase

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: experimental	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.722

A0A087WTR9

(UniProtKB/TrEmbl/P) Details

Protein Mdm4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.722

A0A087WUE3

(UniProtKB/TrEmbl/P) Details

Protein Mdm4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.722

A0A087WZ58

(UniProtKB/TrEmbl/P) Details

Protein Mdm4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.722

Q68DC0

(UniProtKB/TrEmbl/P) Details

MDM4 protein variant G

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.722

A0A087WVR4

(UniProtKB/TrEmbl/P) Details

Myc proto-oncogene protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.722

H3BMS0

(UniProtKB/TrEmbl/P) Details

RNA-binding protein with serine-rich domain 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.722

A0A0U1RRA6

(UniProtKB/TrEmbl/P) Details

R3H domain-containing protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.722

B5MCG9

(UniProtKB/TrEmbl/P) Details

R3H domain-containing protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.722

B7Z673

(UniProtKB/TrEmbl/P) Details

cDNA, FLJ79136, highly similar to Dapper homolog 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.722

A0A087WTF0

(UniProtKB/TrEmbl/P) Details

Protein tyrosine phosphatase domain-containing protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.722

A0A087WT22

(UniProtKB/TrEmbl/P) Details

Cellular tumor antigen p53

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.722

A0A087WXZ1

(UniProtKB/TrEmbl/P) Details

Cellular tumor antigen p53

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.722

A0A087X1Q1

(UniProtKB/TrEmbl/P) Details

Cellular tumor antigen p53

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.72

A0A0B4J1S8

(UniProtKB/TrEmbl/P) Details

Phosphatidylinositol 4-kinase beta

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.717

Q9UII7

(UniProtKB/TrEmbl/P) Details

E-cadherin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Extracellular	Extracellular region (GO:0005576)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.709

Q59FS6

(UniProtKB/TrEmbl/P) Details

Double minute 4 homolog variant

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.7

Q59H88

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.7

Q8N4S3

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.7

Q1ZYQ1

(UniProtKB/TrEmbl/P) Details

Tubulin alpha chain

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.7

Q5SU16

(UniProtKB/TrEmbl/P) Details

Tubulin beta chain

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.7

A4QPA9

(UniProtKB/TrEmbl/P) Details

Mitogen-activated protein kinase kinase 1, isoform CRA_a

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.7

Q17RV3

(UniProtKB/TrEmbl/P) Details

Leucine-rich repeat kinase 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.7

A0A0A0MRE7

(UniProtKB/TrEmbl/P) Details

Bcl-2-like protein 11

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.7

A0A0C4DH20

(UniProtKB/TrEmbl/P) Details

Bcl-2-like protein 11

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.7

E7ESL9

(UniProtKB/TrEmbl/P) Details

Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.7

Q59G02

(UniProtKB/TrEmbl/P) Details

PCTAIRE protein kinase 3 isoform b variant

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.7

Q53RG0

(UniProtKB/TrEmbl/P) Details

Eukaryotic translation initiation factor 4E member 2, isoform CRA_c

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.7

A5D8Z4

(UniProtKB/TrEmbl/P) Details

WNK1 protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.7

Q9H4N8

(UniProtKB/TrEmbl/P) Details

Homo sapiens clone CDABP0046 mRNA sequence

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.7

Q5U077

(UniProtKB/TrEmbl/P) Details

L-lactate dehydrogenase

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.7

A2I2P0

(UniProtKB/TrEmbl/P) Details

Cryptochrome 1 (Photolyase-like), isoform CRA_a

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.7

A0A0A0MR12

(UniProtKB/TrEmbl/P) Details

Protein FAM189A2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.652

Q8WU02

(UniProtKB/TrEmbl/P) Details

C9orf61 protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.7	Predicted: pTarget method	LOCATE	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.64

A7E2E5

(UniProtKB/TrEmbl/P) Details

Phosphodiesterase

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.64

B5M450

(UniProtKB/TrEmbl/P) Details

Anion exchange protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.64

B4E0R1

(UniProtKB/TrEmbl/P) Details

Integrin beta

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.64

B7Z2I3

(UniProtKB/TrEmbl/P) Details

Receptor protein-tyrosine kinase

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.64

E7BSV0

(UniProtKB/TrEmbl/P) Details

Receptor protein-tyrosine kinase

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.64

F2YGG7

(UniProtKB/TrEmbl/P) Details

Receptor protein-tyrosine kinase

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.64

X5DR71

(UniProtKB/TrEmbl/P) Details

Tyrosine-protein kinase receptor

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.64

A0A024QZ30

(UniProtKB/TrEmbl/P) Details

Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.64

A0A024R730

(UniProtKB/TrEmbl/P) Details

Cystic fibrosis transmembrane conductance regulator

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.631

Q8IXP7

(UniProtKB/TrEmbl/P) Details

SAMD4B protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P31946

Interaction Score

0.631

Q53GP3

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.631

Q8NFJ4

(UniProtKB/TrEmbl/P) Details

Testis-specific kinase-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.631

Q6MZW8

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein DKFZp686G14213

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.631

A4D2J9

(UniProtKB/TrEmbl/P) Details

Calcium/calmodulin-dependent protein kinase (CaM kinase) II beta

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.631

Q6IA61

(UniProtKB/TrEmbl/P) Details

C14orf133 protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.631

Q8TEF4

(UniProtKB/TrEmbl/P) Details

FLJ00243 protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.631

Q6PJJ8

(UniProtKB/TrEmbl/P) Details

TBC1D1 protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.631

Q8NC59

(UniProtKB/TrEmbl/P) Details

cDNA FLJ32620 fis, clone STOMA2000386, highly similar to TBC1 domain family member 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.55

Q53FV0

(UniProtKB/TrEmbl/P) Details

Prohibitin variant

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: experimental	eSLDB	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.408

A8K968

(UniProtKB/TrEmbl/P) Details

Band 4.1-like protein 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Plasma membrane (GO:0005886)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.408

S6FRS6

(UniProtKB/TrEmbl/P) Details

SAM domain, SH3 domain and nuclear localization signals 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Plasma membrane (GO:0005886)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.408

B2R4S9

(UniProtKB/TrEmbl/P) Details

Histone H2B

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.408

V9HWC9

(UniProtKB/TrEmbl/P) Details

Superoxide dismutase [Cu-Zn]

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.382

E9PEA7

(UniProtKB/TrEmbl/P) Details

SH3 and cysteine-rich domain-containing protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleoplasm (GO:0005654)	0.3	Unknown: unspecified method	The Human Protein Atlas	PubMed
Membrane	Plasma membrane (GO:0005886)	0.3	Unknown: unspecified method	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.363

A0A087WVP2

(UniProtKB/TrEmbl/P) Details

FERM domain containing 5, isoform CRA_e

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Golgi apparatus (GO:0005794)	0.3	Unknown: unspecified method	The Human Protein Atlas	PubMed
Cytosol	Centrosome (GO:0005813)	0.3	Unknown: unspecified method	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.363

B5MC67

(UniProtKB/TrEmbl/P) Details

FERM domain-containing protein 5

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Golgi apparatus (GO:0005794)	0.3	Unknown: unspecified method	The Human Protein Atlas	PubMed
Cytosol	Centrosome (GO:0005813)	0.3	Unknown: unspecified method	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.363

H0YKW6

(UniProtKB/TrEmbl/P) Details

FERM domain containing 5, isoform CRA_b

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Golgi apparatus (GO:0005794)	0.3	Unknown: unspecified method	The Human Protein Atlas	PubMed
Cytosol	Centrosome (GO:0005813)	0.3	Unknown: unspecified method	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.357

Q05C90

(UniProtKB/TrEmbl/P) Details

DENND4A protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Integral to membrane (GO:0016021)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.357

Q9HCG4

(UniProtKB/TrEmbl/P) Details

KIAA1608 protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Integral to membrane (GO:0016021)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.273

Q96IL0

(UniProtKB/Swiss-Prot/P) Details

Apoptogenic protein 1, mitochondrial

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Mitochondrion	Mitochondrion (GO:0005739)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.91	Predicted: inferred from biological aspect of ancestor	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.24

E9PEX6

(UniProtKB/TrEmbl/P) Details

Dihydrolipoyl dehydrogenase

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P31946

Interaction Score

0.21

Q8WW19

(UniProtKB/TrEmbl/P) Details

SAMD4A protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

⇦ Back to the Search Page
⇦ Back to Starting Page

P31946

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

P31946

P37840

Alpha-synuclein

Localizations:

Interaction Source Database:

Interaction Source Publication:

P31946

P00441

Superoxide dismutase [Cu-Zn]

Localizations:

Interaction Source Database:

Interaction Source Publication:

P31946

Q5S007

Leucine-rich repeat serine/threonine-protein kinase 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

P31946

P08238

Heat shock protein HSP 90-beta

Localizations:

Interaction Source Database:

Interaction Source Publication:

P31946

P10636

Microtubule-associated protein tau

Localizations:

Interaction Source Database:

Interaction Source Publication:

P31946

Q9H0H5

Rac GTPase-activating protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

P31946

P0DMV8

Heat shock 70 kDa protein 1A

Localizations:

Interaction Source Database:

Interaction Source Publication:

P31946

P0DMV9

Heat shock 70 kDa protein 1B

Localizations:

Interaction Source Database:

Interaction Source Publication:

P31946

Q14247

Src substrate cortactin

Localizations:

Interaction Source Database:

Interaction Source Publication:

P31946

O75122

CLIP-associating protein 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

P31946

O00429

Dynamin-1-like protein

Localizations:

Interaction Source Database:

Interaction Source Publication:

P31946

P49815

Tuberin

Localizations:

Interaction Source Database:

Interaction Source Publication:

P31946