P34820

Bone morphogenetic protein 8B    //   UniProt Profile 

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Species

 H. sapiens

Number of Interactions

 16 / 27

Average Interaction Score

 0.565

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.8 Experimental: experimental eSLDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.973 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular region (GO:0005576) 0.973 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.973 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

P34820

Interaction Score
0.997

P12644

(UniProtKB/Swiss-Prot/P) Details

Bone morphogenetic protein 4

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.86 Experimental: experimental eSLDB PubMed 
Secretory-pathway Endoplasmic reticulum lumen (GO:0005788) 0.86 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 1 Experimental: experimental eSLDB PubMed 
Extracellular Extracellular region (GO:0005576) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Extracellular Extracellular region (GO:0005576) 1 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular region (GO:0005576) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Extracellular Extracellular matrix (GO:0031012) 1 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed 

P34820

Interaction Score
0.996

Q03405

(UniProtKB/Swiss-Prot/P) Details

Urokinase plasminogen activator surface receptor

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.902 Experimental: experimental eSLDB PubMed 
Membrane Cell surface (GO:0009986) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum lumen (GO:0005788) 0.902 Unknown: traceable author statement GO PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 0.902 Unknown: traceable author statement GO PubMed 
Membrane Invadopodium membrane (GO:0071438) 1 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Membrane (GO:0016020) 1 Experimental: experimental eSLDB PubMed 
Membrane Membrane (GO:0016020) 1 Experimental: experimental MatrixDB PubMed 
Membrane Extrinsic to membrane (GO:0019898) 1 Unknown: traceable author statement GO PubMed 
Membrane Anchored to membrane (GO:0031225) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Integral to membrane (GO:0016021) 1 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Unknown: non-traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Integral to plasma membrane (GO:0005887) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Focal adhesion (GO:0005925) 1 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P34820

Interaction Score
0.993

Q8TEU8

(UniProtKB/Swiss-Prot/P) Details

WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.982 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular region (GO:0005576) 0.982 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.982 Experimental: inferred from direct assay GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P34820

Interaction Score
0.986

Q96NZ8

(UniProtKB/Swiss-Prot/P) Details

WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.937 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.937 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular region (GO:0005576) 0.937 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P34820

Interaction Score
0.984

P06241

(UniProtKB/Swiss-Prot/P) Details

Tyrosine-protein kinase Fyn

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cell body (GO:0044297) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Perinuclear endoplasmic reticulum (GO:0097038) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: inferred from sequence or structural similarity GO PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Predicted: inferred from sequence or structural similarity GO PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Experimental: experimental Human Proteinpedia PubMed 
Secretory-pathway Endosome (GO:0005768) 0.8 Experimental: inferred from direct assay GO PubMed 
Cytosol Actin filament (GO:0005884) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Glial cell projection (GO:0097386) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Dendrite (GO:0030425) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Postsynaptic density (GO:0014069) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane raft (GO:0045121) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Extrinsic to internal side of plasma membrane (GO:0031234) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P34820

Interaction Score
0.984

Q16635

(UniProtKB/Swiss-Prot/P) Details

Tafazzin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.86 Experimental: experimental eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.996 Predicted: SVM decision tree eSLDB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.996 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.996 Predicted: pTarget method LOCATE PubMed 
Mitochondrion Mitochondrial membrane (GO:0031966) 0.996 Predicted: inferred from biological aspect of ancestor GO PubMed 
Mitochondrion Mitochondrial inner membrane (GO:0005743) 0.996 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.8 Experimental: experimental Human Proteinpedia PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Intrinsic to membrane (GO:0031224) 0.992 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.992 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.992 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.992 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P34820

Interaction Score
0.945

P00519

(UniProtKB/Swiss-Prot/P) Details

Tyrosine-protein kinase ABL1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Cell leading edge (GO:0031252) 0.937 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Neuronal cell body (GO:0043025) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 1 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.3 Unknown: non-traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleolus (GO:0005730) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear membrane (GO:0031965) 1 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nuclear body (GO:0016604) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear body (GO:0016604) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Macromolecular complex (GO:0032991) 1 Predicted: inferred from physical interaction GO PubMed 
Cytosol Actin cytoskeleton (GO:0015629) 1 Unknown: traceable author statement GO PubMed 
Membrane Dendrite (GO:0030425) 0.937 Predicted: inferred from sequence or structural similarity GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Extrinsic to internal side of plasma membrane (GO:0031234) 0.937 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P34820

Interaction Score
0.778

P34897

(UniProtKB/Swiss-Prot/P) Details

Serine hydroxymethyltransferase, mitochondrial

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.998 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.998 Predicted: PAML algorithm PA-GOSUB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 1 Experimental: experimental eSLDB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 1 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 1 Experimental: experimental Organelle PubMed 
Mitochondrion Mitochondrion (GO:0005739) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Mitochondrion Mitochondrial matrix (GO:0005759) 1 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrial nucleoid (GO:0042645) 1 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrial intermembrane space (GO:0005758) 1 Unknown: inferred from electronic annotation GO PubMed 
Mitochondrion Mitochondrial inner membrane (GO:0005743) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Experimental: experimental Human Proteinpedia PubMed 
Nucleus BRISC complex (GO:0070552) 0.992 Experimental: inferred from direct assay GO PubMed 
Cytosol Microtubule cytoskeleton (GO:0015630) 0.998 Experimental: inferred from direct assay GO PubMed 
Cytosol Microtubule cytoskeleton (GO:0015630) 0.998 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.998 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P34820

Interaction Score
0.745

Q9HCE1

(UniProtKB/Swiss-Prot/P) Details

Putative helicase MOV-10

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasmic mRNA processing body (GO:0000932) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular space (GO:0005615) 0.3 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P34820

Interaction Score
0.64

M0R1I2

(UniProtKB/TrEmbl/P) Details

Urokinase plasminogen activator surface receptor

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Plasma membrane (GO:0005886) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P34820

Interaction Score
0

Q59E96

(UniProtKB/TrEmbl/P) Details

Nuclear RNA export factor 1 variant

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.8 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P34820

Interaction Score
0

Q9UBU9

(UniProtKB/Swiss-Prot/P) Details

Nuclear RNA export factor 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.972 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.972 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.972 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nuclear inclusion body (GO:0042405) 1 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nuclear pore (GO:0005643) 1 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nuclear speck (GO:0016607) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Transcription export complex (GO:0000346) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P34820

Interaction Score
0

Q5JR04

(UniProtKB/TrEmbl/P) Details

Mov10, Moloney leukemia virus 10, homolog (Mouse), isoform CRA_a

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.94 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.94 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P34820

Interaction Score
0

Q5HYG8

(UniProtKB/TrEmbl/P) Details

Serine hydroxymethyltransferase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Mitochondrion Mitochondrion (GO:0005739) 0.8 Experimental: experimental eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P34820

Interaction Score
0

Q5BJF5

(UniProtKB/TrEmbl/P) Details

Serine hydroxymethyltransferase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P34820

Interaction Score
0

Q13616

(UniProtKB/Swiss-Prot/P) Details

Cullin-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cullin-RING ubiquitin ligase complex (GO:0031461) 0.999 Experimental: inferred from direct assay GO PubMed 
Cytosol SCF ubiquitin ligase complex (GO:0019005) 0.999 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytosol (GO:0005829) 0.999 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 0.972 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleolus (GO:0005730) 0.972 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.972 Unknown: traceable author statement GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

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ComPPI is published in Nucleic Acids Research Database Issue 2015