P35368

Alpha-1B adrenergic receptor    //   UniProt Profile 

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Species

 H. sapiens

Number of Interactions

 16 / 18

Average Interaction Score

 0.983

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.8 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.96 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear membrane (GO:0031965) 0.96 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Predicted: SVM decision tree eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Caveola (GO:0005901) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Integral to plasma membrane (GO:0005887) 1 Unknown: traceable author statement GO PubMed 

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

P35368

Interaction Score
1

P15311

(UniProtKB/Swiss-Prot/P) Details

Ezrin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
N/A TCR signalosome (GO:0036398) 0.8 Experimental: inferred from direct assay GO PubMed 
Membrane Myelin sheath (GO:0043209) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Cell tip (GO:0051286) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cell body (GO:0044297) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Apical part of cell (GO:0045177) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.988 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Fibrillar center (GO:0001650) 0.988 Experimental: inferred from direct assay GO PubMed 
Nucleus Macromolecular complex (GO:0032991) 0.988 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endosome (GO:0005768) 0.8 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Experimental: experimental Organelle PubMed 
Cytosol Cilium basal body (GO:0036064) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cortical cytoskeleton (GO:0030863) 1 Unknown: traceable author statement GO PubMed 
Cytosol Actin cytoskeleton (GO:0015629) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Actin filament (GO:0005884) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Cell periphery (GO:0071944) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Cell projection (GO:0042995) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Astrocyte projection (GO:0097449) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Microspike (GO:0044393) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Uropod (GO:0001931) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Ruffle (GO:0001726) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Ruffle membrane (GO:0032587) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Microvillus (GO:0005902) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Schwann cell microvillus (GO:0097454) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Microvillus membrane (GO:0031528) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Invadopodium (GO:0071437) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Brush border (GO:0005903) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Filopodium (GO:0030175) 1 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.86 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular space (GO:0005615) 0.86 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 1 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 1 Experimental: experimental MatrixDB PubMed 
Membrane Extrinsic to membrane (GO:0019898) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane T-tubule (GO:0030315) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Immunological synapse (GO:0001772) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Apical plasma membrane (GO:0016324) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Basolateral plasma membrane (GO:0016323) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Vesicle (GO:0031982) 1 Unknown: HDA GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 
Membrane Focal adhesion (GO:0005925) 1 Unknown: HDA GO PubMed 

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed 

P35368

Interaction Score
1

P29475

(UniProtKB/Swiss-Prot/P) Details

Nitric oxide synthase, brain

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Photoreceptor inner segment (GO:0001917) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Unknown: traceable author statement GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Predicted: pTarget method LOCATE PubMed 
Cytosol Sarcoplasmic reticulum (GO:0016529) 0.999 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.999 Unknown: traceable author statement GO PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 0.999 Predicted: inferred from sequence or structural similarity GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: inferred from sequence or structural similarity GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.988 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.988 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Macromolecular complex (GO:0032991) 0.988 Predicted: inferred from sequence or structural similarity GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Z disc (GO:0030018) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 0.999 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Dendritic spine (GO:0043197) 1 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane raft (GO:0045121) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Sarcolemma (GO:0042383) 1 Experimental: inferred from direct assay GO PubMed 
Membrane T-tubule (GO:0030315) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Caveola (GO:0005901) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Synapse (GO:0045202) 1 Predicted: inferred from sequence or structural similarity GO PubMed 

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed 

P35368

Interaction Score
1

Q96SB3

(UniProtKB/Swiss-Prot/P) Details

Neurabin-2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Protein phosphatase type 1 complex (GO:0000164) 0.971 Unknown: traceable author statement GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.971 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.971 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.996 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.996 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 0.996 Experimental: experimental Organelle PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.996 Experimental: inferred from mutant phenotype GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 0.971 Unknown: inferred from electronic annotation GO PubMed 
Membrane Ruffle membrane (GO:0032587) 0.999 Experimental: inferred from direct assay GO PubMed 
Membrane Lamellipodium (GO:0030027) 0.999 Experimental: inferred from direct assay GO PubMed 
Membrane Filopodium (GO:0030175) 0.999 Experimental: inferred from direct assay GO PubMed 
Membrane Dendritic spine (GO:0043197) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.999 Experimental: inferred from direct assay GO PubMed 
Membrane Adherens junction (GO:0005912) 0.999 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

HPRD, IntAct

Interaction Source Publication:

PubMed 

P35368

Interaction Score
1

P35348

(UniProtKB/Swiss-Prot/P) Details

Alpha-1A adrenergic receptor

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.86 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.96 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear membrane (GO:0031965) 0.96 Experimental: inferred from direct assay GO PubMed 
Cytosol Z disc (GO:0030018) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.999 Predicted: SVM decision tree eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.999 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.999 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 0.999 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane T-tubule (GO:0030315) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Membrane Caveola (GO:0005901) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.999 Unknown: traceable author statement GO PubMed 

Interaction Source Database:

HPRD, BioGRID

Interaction Source Publication:

PubMed , PubMed 

P35368

Interaction Score
1

P50148

(UniProtKB/Swiss-Prot/P) Details

Guanine nucleotide-binding protein G(q) subunit alpha

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cell body (GO:0044297) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Unknown: traceable author statement GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: pTarget method LOCATE PubMed 
Nucleus Nuclear membrane (GO:0031965) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nuclear speck (GO:0016607) 0.86 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Lysosomal membrane (GO:0005765) 0.999 Unknown: HDA GO PubMed 
Membrane Dendrite (GO:0030425) 0.998 Unknown: inferred from electronic annotation GO PubMed 
Membrane Photoreceptor outer segment (GO:0001750) 0.998 Predicted: inferred from sequence or structural similarity GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.998 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.998 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 0.998 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Heterotrimeric G-protein complex (GO:0005834) 0.998 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.999 Unknown: HDA GO PubMed 

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed 

P35368

Interaction Score
1

Q14315

(UniProtKB/Swiss-Prot/P) Details

Filamin-C

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Sarcoplasm (GO:0016528) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.8 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Costamere (GO:0043034) 1 Unknown: traceable author statement GO PubMed 
Cytosol Z disc (GO:0030018) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Experimental: experimental Organelle PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.994 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.994 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Sarcolemma (GO:0042383) 0.994 Experimental: inferred from direct assay GO PubMed 
Membrane Focal adhesion (GO:0005925) 0.994 Unknown: HDA GO PubMed 

Interaction Source Database:

HPRD, IntAct

Interaction Source Publication:

PubMed 

P35368

Interaction Score
1

P21917

(UniProtKB/Swiss-Prot/P) Details

D(4) dopamine receptor

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Integral to membrane (GO:0016021) 1 Predicted: SVM decision tree eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to plasma membrane (GO:0005887) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct, DIP

Interaction Source Publication:

PubMed 

P35368

Interaction Score
1

P02768

(UniProtKB/Swiss-Prot/P) Details

Serum albumin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 1 Experimental: experimental eSLDB PubMed 
Membrane Myelin sheath (GO:0043209) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.972 Experimental: experimental Human Proteinpedia PubMed 
Nucleus Nucleus (GO:0005634) 0.972 Unknown: HDA GO PubMed 
Nucleus Nucleus (GO:0005634) 0.972 Experimental: experimental Human Proteinpedia PubMed 
Nucleus Macromolecular complex (GO:0032991) 0.972 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum lumen (GO:0005788) 1 Unknown: traceable author statement GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Platelet alpha granule lumen (GO:0031093) 1 Unknown: traceable author statement GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 0.972 Experimental: experimental Human Proteinpedia PubMed 
Extracellular Extracellular region (GO:0005576) 0.991 Unknown: non-traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.991 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular region (GO:0005576) 0.991 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.991 Experimental: inferred from direct assay GO PubMed 
Extracellular Blood microparticle (GO:0072562) 0.991 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 0.86 Experimental: experimental MatrixDB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.972 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

P35368

Interaction Score
0.999

P42224

(UniProtKB/Swiss-Prot/P) Details

Signal transducer and activator of transcription 1-alpha/beta

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleolus (GO:0005730) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Macromolecular complex (GO:0032991) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear chromatin (GO:0000790) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Dendrite (GO:0030425) 0.91 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Axon (GO:0030424) 0.91 Predicted: inferred from sequence or structural similarity GO PubMed 

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed 

P35368

Interaction Score
0.999

Q96CW1

(UniProtKB/Swiss-Prot/P) Details

AP-2 complex subunit mu

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.928 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.928 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Lysosomal membrane (GO:0005765) 0.928 Unknown: traceable author statement GO PubMed 
Cytosol Endolysosome membrane (GO:0036020) 0.928 Unknown: traceable author statement GO PubMed 
Secretory-pathway Endocytic vesicle membrane (GO:0030666) 0.657 Unknown: traceable author statement GO PubMed 
Secretory-pathway Clathrin-coated endocytic vesicle (GO:0045334) 0.657 Unknown: non-traceable author statement GO PubMed 
Secretory-pathway Clathrin-coated endocytic vesicle membrane (GO:0030669) 0.657 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane AP-2 adaptor complex (GO:0030122) 0.972 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.972 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.972 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.928 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID, HPRD

Interaction Source Publication:

PubMed 

P35368

Interaction Score
0.999

P29992

(UniProtKB/Swiss-Prot/P) Details

Guanine nucleotide-binding protein subunit alpha-11

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.897 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.897 Unknown: traceable author statement GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: pTarget method LOCATE PubMed 
Cytosol Lysosomal membrane (GO:0005765) 0.897 Unknown: HDA GO PubMed 
Membrane Photoreceptor outer segment (GO:0001750) 0.987 Predicted: inferred from sequence or structural similarity GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.987 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.987 Experimental: experimental Organelle PubMed 
Membrane Heterotrimeric G-protein complex (GO:0005834) 0.987 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.897 Unknown: HDA GO PubMed 

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed 

P35368

Interaction Score
0.998

P17252

(UniProtKB/Swiss-Prot/P) Details

Protein kinase C alpha type

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.51 Unknown: HDA GO PubMed 
Mitochondrion Mitochondrial membrane (GO:0031966) 0.51 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.3 Unknown: traceable author statement GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.8 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.96 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed 

P35368

Interaction Score
0.996

P01857

(UniProtKB/Swiss-Prot/P) Details

Immunoglobulin heavy constant gamma 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Immunoglobulin complex, circulating (GO:0042571) 0.982 Predicted: inferred from biological aspect of ancestor GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.931 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.931 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular space (GO:0005615) 0.931 Unknown: HDA GO PubMed 
Extracellular Blood microparticle (GO:0072562) 0.931 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 0.982 Experimental: experimental MatrixDB PubMed 
Membrane External side of plasma membrane (GO:0009897) 0.982 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.3 Unknown: HDA GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P35368

Interaction Score
0.975

P10523

(UniProtKB/Swiss-Prot/P) Details

S-arrestin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Photoreceptor inner segment (GO:0001917) 0.902 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.937 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.937 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytosol (GO:0005829) 0.937 Unknown: traceable author statement GO PubMed 
Membrane Photoreceptor outer segment (GO:0001750) 0.902 Experimental: inferred from direct assay GO PubMed 
Membrane Membrane (GO:0016020) 0.902 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed 

P35368

Interaction Score
0.962

O00303

(UniProtKB/Swiss-Prot/P) Details

Eukaryotic translation initiation factor 3 subunit F

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.986 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Eukaryotic 48S preinitiation complex (GO:0033290) 0.986 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Eukaryotic 43S preinitiation complex (GO:0016282) 0.986 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytosol (GO:0005829) 0.986 Unknown: traceable author statement GO PubMed 
Cytosol Cytosol (GO:0005829) 0.986 Unknown: unspecified method The Human Protein Atlas PubMed 
Cytosol Eukaryotic translation initiation factor 3 complex (GO:0005852) 0.986 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleolus (GO:0005730) 0.3 Unknown: unspecified method The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.3 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P35368

Interaction Score
0.8

E9PFW3

(UniProtKB/TrEmbl/P) Details

AP-2 complex subunit mu

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Plasma membrane (GO:0005886) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

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ComPPI is published in Nucleic Acids Research Database Issue 2015