P38484

Interferon gamma receptor 2 // UniProt Profile

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Species	H. sapiens
Number of Interactions	38 / 41
Average Interaction Score	0.903

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.952	Unknown: HDA	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.952	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.952	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.952	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle membrane (GO:0030659)	0.952	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.971	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.971	Unknown: HDA	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.971	Experimental: experimental	Organelle	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	0.971	Unknown: traceable author statement	GO	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

P38484

Interaction Score

Q5BJF2

(UniProtKB/Swiss-Prot/P) Details

Sigma intracellular receptor 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear membrane (GO:0031965)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear membrane (GO:0031965)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.958	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Rough endoplasmic reticulum (GO:0005791)	0.958	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Rough endoplasmic reticulum membrane (GO:0030867)	0.958	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Lysosome (GO:0005764)	0.992	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.992	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.992	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.992	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P38484

Interaction Score

Q15848

(UniProtKB/Swiss-Prot/P) Details

Adiponectin

P38484

Interaction Score

0.999

O75396

(UniProtKB/Swiss-Prot/P) Details

Vesicle-trafficking protein SEC22b

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endomembrane system (GO:0012505)	0.96	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum-Golgi intermediate compartment (GO:0005793)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum-Golgi intermediate compartment membrane (GO:0033116)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Phagocytic vesicle membrane (GO:0030670)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Melanosome (GO:0042470)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	ER to Golgi transport vesicle membrane (GO:0012507)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Synaptic vesicle (GO:0008021)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Transport vesicle (GO:0030133)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.96	Experimental: experimental	Human Proteinpedia	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.79	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	SNARE complex (GO:0031201)	0.79	Predicted: inferred from biological aspect of ancestor	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P38484

Interaction Score

0.999

O60674

(UniProtKB/Swiss-Prot/P) Details

Tyrosine-protein kinase JAK2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.994	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear matrix (GO:0016363)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.994	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.994	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endosome lumen (GO:0031904)	0.3	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Membrane raft (GO:0045121)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Extrinsic to internal side of plasma membrane (GO:0031234)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Caveola (GO:0005901)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

HPRD, BioGRID

Interaction Source Publication:

PubMed

, PubMed

P38484

Interaction Score

0.998

Q13557

(UniProtKB/Swiss-Prot/P) Details

Calcium/calmodulin-dependent protein kinase type II subunit delta

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Sarcoplasmic reticulum membrane (GO:0033017)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.79	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.79	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endocytic vesicle membrane (GO:0030666)	0.3	Unknown: traceable author statement	GO	PubMed
Membrane	Neuron projection (GO:0043005)	0.996	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.996	Unknown: HDA	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.996	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Sarcolemma (GO:0042383)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed

P38484

Interaction Score

0.998

Q8N511

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 199

P38484

Interaction Score

0.997

Q07325

(UniProtKB/Swiss-Prot/P) Details

C-X-C motif chemokine 9

P38484

Interaction Score

0.997

P08758

(UniProtKB/Swiss-Prot/P) Details

Annexin A5

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular (GO:0005622)	0.996	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.996	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.996	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	0.996	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nuclear membrane (GO:0031965)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.902	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.902	Experimental: experimental	MatrixDB	PubMed
Extracellular	Endothelial microparticle (GO:0072563)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Membrane (GO:0016020)	0.931	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.931	Experimental: experimental	MatrixDB	PubMed
Membrane	External side of plasma membrane (GO:0009897)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.996	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.931	Unknown: HDA	GO	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

P38484

Interaction Score

0.997

P01579

(UniProtKB/Swiss-Prot/P) Details

Interferon gamma

P38484

Interaction Score

0.996

P15260

(UniProtKB/Swiss-Prot/P) Details

Interferon gamma receptor 1

P38484

Interaction Score

0.994

Q8TBM7

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 254

P38484

Interaction Score

0.994

Q53HI1

(UniProtKB/Swiss-Prot/P) Details

Protein unc-50 homolog

P38484

Interaction Score

0.993

P11686

(UniProtKB/Swiss-Prot/P) Details

Pulmonary surfactant-associated protein C

P38484

Interaction Score

0.993

Q7Z2K6

(UniProtKB/Swiss-Prot/P) Details

Endoplasmic reticulum metallopeptidase 1

P38484

Interaction Score

0.992

Q01453

(UniProtKB/Swiss-Prot/P) Details

Peripheral myelin protein 22

P38484

Interaction Score

0.991

Q96EY1

(UniProtKB/Swiss-Prot/P) Details

DnaJ homolog subfamily A member 3, mitochondrial

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.972	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial matrix (GO:0005759)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Actin filament (GO:0005884)	0.972	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Extrinsic to plasma membrane (GO:0019897)	0.981	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.981	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Neuromuscular junction (GO:0031594)	0.981	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Postsynaptic membrane (GO:0045211)	0.981	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

BioGRID, HPRD

Interaction Source Publication:

PubMed

P38484

Interaction Score

0.991

Q8IX05

(UniProtKB/Swiss-Prot/P) Details

CD302 antigen

P38484

Interaction Score

0.99

Q8N5M9

(UniProtKB/Swiss-Prot/P) Details

Protein jagunal homolog 1

P38484

Interaction Score

0.988

Q5QGT7

(UniProtKB/Swiss-Prot/P) Details

Receptor-transporting protein 2

P38484

Interaction Score

0.986

Q6UX98

(UniProtKB/Swiss-Prot/P) Details

Probable palmitoyltransferase ZDHHC24

P38484

Interaction Score

0.986

A0PK00

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 120B

P38484

Interaction Score

0.986

Q9Y5U4

(UniProtKB/Swiss-Prot/P) Details

Insulin-induced gene 2 protein

P38484

Interaction Score

0.983

Q9NWF4

(UniProtKB/Swiss-Prot/P) Details

Solute carrier family 52, riboflavin transporter, member 1

P38484

Interaction Score

0.983

P47884

(UniProtKB/Swiss-Prot/P) Details

Olfactory receptor 1D4

P38484

Interaction Score

0.965

Q15717

(UniProtKB/Swiss-Prot/P) Details

ELAV-like protein 1

P38484

Interaction Score

0.959

Q96F15

(UniProtKB/Swiss-Prot/P) Details

GTPase IMAP family member 5

P38484

Interaction Score

0.959

Q9H2L4

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 60

P38484

Interaction Score

0.932

E9PF82

(UniProtKB/TrEmbl/P) Details

Calcium/calmodulin-dependent protein kinase type II subunit delta

P38484

Interaction Score

0.932

E9PBG7

(UniProtKB/TrEmbl/P) Details

Calcium/calmodulin-dependent protein kinase type II subunit delta

P38484

Interaction Score

0.932

D6R938

(UniProtKB/TrEmbl/P) Details

Calcium/calmodulin-dependent protein kinase (CaM kinase) II delta, isoform CRA_e

P38484

Interaction Score

0.872

P61513

(UniProtKB/Swiss-Prot/P) Details

60S ribosomal protein L37a

P38484

Interaction Score

0.824

Q9BZL3

(UniProtKB/Swiss-Prot/P) Details

Small integral membrane protein 3

P38484

Interaction Score

0.8

P04150

(UniProtKB/Swiss-Prot/P) Details

Glucocorticoid receptor

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.972	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.972	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial matrix (GO:0005759)	0.972	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Spindle (GO:0005819)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	0.999	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

P38484

Interaction Score

0.8

Q14258

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin/ISG15 ligase TRIM25

P38484

Interaction Score

0.752

B4DYV1

(UniProtKB/TrEmbl/P) Details

Tyrosine-protein kinase

P38484

Interaction Score

0.752

A8K910

(UniProtKB/TrEmbl/P) Details

Tyrosine-protein kinase

P38484

Interaction Score

Q59E88

(UniProtKB/TrEmbl/P) Details

DnaJ (Hsp40) homolog, subfamily A, member 3 variant

P38484

Interaction Score

Q53G26

(UniProtKB/TrEmbl/P) Details

DnaJ (Hsp40) homolog, subfamily A, member 3 variant

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P38484

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

P38484

Q5BJF2

Sigma intracellular receptor 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

P38484

Q15848

Adiponectin

Localizations:

Interaction Source Database:

Interaction Source Publication:

P38484

O75396

Vesicle-trafficking protein SEC22b

Localizations:

Interaction Source Database:

Interaction Source Publication:

P38484

O60674

Tyrosine-protein kinase JAK2

Localizations:

Interaction Source Database:

Interaction Source Publication:

P38484

Q13557

Calcium/calmodulin-dependent protein kinase type II subunit delta

Localizations:

Interaction Source Database:

Interaction Source Publication:

P38484

Q8N511

Transmembrane protein 199

Localizations:

Interaction Source Database:

Interaction Source Publication:

P38484

Q07325

C-X-C motif chemokine 9

Localizations:

Interaction Source Database:

Interaction Source Publication:

P38484

P08758

Annexin A5

Localizations:

Interaction Source Database:

Interaction Source Publication:

P38484

P01579

Interferon gamma

Localizations:

Interaction Source Database:

Interaction Source Publication:

P38484

P15260

Interferon gamma receptor 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

P38484

Q8TBM7

Transmembrane protein 254

Localizations:

Interaction Source Database:

Interaction Source Publication:

P38484

Q53HI1

Protein unc-50 homolog

Localizations:

Interaction Source Database:

Interaction Source Publication:

P38484