P42568

Protein AF-9 // UniProt Profile

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Species	H. sapiens
Number of Interactions	84 / 114
Average Interaction Score	0.905

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.86	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Transcription elongation factor complex (GO:0008023)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Chromosome (GO:0005694)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.86	Unknown: HDA	GO	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

P42568

Interaction Score

O14980

(UniProtKB/Swiss-Prot/P) Details

Exportin-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear membrane (GO:0031965)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear membrane (GO:0031965)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear envelope (GO:0005635)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Cajal body (GO:0015030)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Kinetochore (GO:0000776)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Experimental: experimental	MatrixDB	PubMed
Extracellular	Host cell (GO:0043657)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed
Secretory-pathway	Annulate lamellae (GO:0005642)	0.8	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P42568

Interaction Score

Q96EB6

(UniProtKB/Swiss-Prot/P) Details

NAD-dependent protein deacetylase sirtuin-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.96	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear inner membrane (GO:0005637)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear envelope (GO:0005635)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	PML body (GO:0016605)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	ESC/E(Z) complex (GO:0035098)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Chromatin silencing complex (GO:0005677)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear chromatin (GO:0000790)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear euchromatin (GO:0005719)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear heterochromatin (GO:0005720)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	RDNA heterochromatin (GO:0033553)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P42568

Interaction Score

Q9NQT5

(UniProtKB/Swiss-Prot/P) Details

Exosome complex component RRP40

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Exosome (RNase complex) (GO:0000178)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Exosome (RNase complex) (GO:0000178)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Cytoplasmic exosome (RNase complex) (GO:0000177)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear exosome (RNase complex) (GO:0000176)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Transcriptionally active chromatin (GO:0035327)	1	Experimental: inferred from mutant phenotype	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P42568

Interaction Score

Q5UIP0

(UniProtKB/Swiss-Prot/P) Details

Telomere-associated protein RIF1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Unknown: unspecified method	The Human Protein Atlas	PubMed
Nucleus	Female pronucleus (GO:0001939)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Male pronucleus (GO:0001940)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nuclear membrane (GO:0031965)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Unknown: unspecified method	The Human Protein Atlas	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.972	Experimental: experimental	eSLDB	PubMed
Cytosol	Spindle midzone (GO:0051233)	0.972	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Site of double-strand break (GO:0035861)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear chromatin (GO:0000790)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Chromosome, telomeric region (GO:0000781)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Condensed chromosome (GO:0000793)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.958	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.958	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.958	Unknown: unspecified method	The Human Protein Atlas	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P42568

Interaction Score

O00541

(UniProtKB/Swiss-Prot/P) Details

Pescadillo homolog

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Preribosome, large subunit precursor (GO:0030687)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	PeBoW complex (GO:0070545)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Condensed chromosome (GO:0000793)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.79	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.79	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P42568

Interaction Score

Q03164

(UniProtKB/Swiss-Prot/P) Details

Histone-lysine N-methyltransferase 2A

P42568

Interaction Score

Q99496

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase RING2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Ubiquitin ligase complex (GO:0000151)	0.94	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	MLL1 complex (GO:0071339)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	PcG protein complex (GO:0031519)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	PRC1 complex (GO:0035102)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Euchromatin (GO:0000791)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Sex chromatin (GO:0001739)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P42568

Interaction Score

P51826

(UniProtKB/Swiss-Prot/P) Details

AF4/FMR2 family member 3

P42568

Interaction Score

Q14839

(UniProtKB/Swiss-Prot/P) Details

Chromodomain-helicase-DNA-binding protein 4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	NuRD complex (GO:0016581)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Unknown: HDA	GO	PubMed
Cytosol	Centrosome (GO:0005813)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear chromatin (GO:0000790)	1	Unknown: HDA	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P42568

Interaction Score

Q96JC9

(UniProtKB/Swiss-Prot/P) Details

ELL-associated factor 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Cajal body (GO:0015030)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Transcription elongation factor complex (GO:0008023)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	ELL-EAF complex (GO:0032783)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Intercellular bridge (GO:0045171)	0.96	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Intercellular bridge (GO:0045171)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P42568

Interaction Score

Q03111

(UniProtKB/Swiss-Prot/P) Details

Protein ENL

P42568

Interaction Score

O60583

(UniProtKB/Swiss-Prot/P) Details

Cyclin-T2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.972	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.972	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Positive transcription elongation factor complex b (GO:0008024)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P42568

Interaction Score

P50750

(UniProtKB/Swiss-Prot/P) Details

Cyclin-dependent kinase 9

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	PML body (GO:0016605)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Transcription elongation factor complex (GO:0008023)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Positive transcription elongation factor complex b (GO:0008024)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Chromosome (GO:0005694)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

P42568

Interaction Score

Q5T3J3

(UniProtKB/Swiss-Prot/P) Details

Ligand-dependent nuclear receptor-interacting factor 1

P42568

Interaction Score

P55197

(UniProtKB/Swiss-Prot/P) Details

Protein AF-10

P42568

Interaction Score

Q6KC79

(UniProtKB/Swiss-Prot/P) Details

Nipped-B-like protein

P42568

Interaction Score

P84243

(UniProtKB/Swiss-Prot/P) Details

Histone H3.3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Unknown: HDA	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear chromosome (GO:0000228)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear chromosome, telomeric region (GO:0000784)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleosome (GO:0000786)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear nucleosome (GO:0000788)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.3	Unknown: traceable author statement	GO	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	MatrixDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P42568

Interaction Score

P63208

(UniProtKB/Swiss-Prot/P) Details

S-phase kinase-associated protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cul7-RING ubiquitin ligase complex (GO:0031467)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	SCF ubiquitin ligase complex (GO:0019005)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	PcG protein complex (GO:0031519)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P42568

Interaction Score

Q9HC52

(UniProtKB/Swiss-Prot/P) Details

Chromobox protein homolog 8

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	PcG protein complex (GO:0031519)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	PRC1 complex (GO:0035102)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear chromatin (GO:0000790)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Heterochromatin (GO:0000792)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

HPRD, DIP, IntAct

Interaction Source Publication:

PubMed

, PubMed

P42568

Interaction Score

Q9Y4A5

(UniProtKB/Swiss-Prot/P) Details

Transformation/transcription domain-associated protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Transcription factor TFTC complex (GO:0033276)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	STAGA complex (GO:0030914)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	PCAF complex (GO:0000125)	1	Unknown: non-traceable author statement	GO	PubMed
Nucleus	NuA4 histone acetyltransferase complex (GO:0035267)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.96	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Swr1 complex (GO:0000812)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P42568

Interaction Score

Q9UHB7

(UniProtKB/Swiss-Prot/P) Details

AF4/FMR2 family member 4

P42568

Interaction Score

Q9HB65

(UniProtKB/Swiss-Prot/P) Details

RNA polymerase II elongation factor ELL3

P42568

Interaction Score

O43491

(UniProtKB/Swiss-Prot/P) Details

Band 4.1-like protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Signalosome (GO:0008180)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.998	Experimental: experimental	Organelle	PubMed
Cytosol	Spectrin (GO:0008091)	0.998	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.998	Unknown: HDA	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P42568

Interaction Score

Q8TEK3

(UniProtKB/Swiss-Prot/P) Details

Histone-lysine N-methyltransferase, H3 lysine-79 specific

P42568

Interaction Score

Q14566

(UniProtKB/Swiss-Prot/P) Details

DNA replication licensing factor MCM6

P42568

Interaction Score

P55199

(UniProtKB/Swiss-Prot/P) Details

RNA polymerase II elongation factor ELL

P42568

Interaction Score

Q8N7H5

(UniProtKB/Swiss-Prot/P) Details

RNA polymerase II-associated factor 1 homolog

P42568

Interaction Score

O60563

(UniProtKB/Swiss-Prot/P) Details

Cyclin-T1

P42568

Interaction Score

O00141

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein kinase Sgk1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.996	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.996	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.79	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.3	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P42568

Interaction Score

Q6P1J9

(UniProtKB/Swiss-Prot/P) Details

Parafibromin

P42568

Interaction Score

Q9BSM1

(UniProtKB/Swiss-Prot/P) Details

Polycomb group RING finger protein 1

P42568

Interaction Score

O00472

(UniProtKB/Swiss-Prot/P) Details

RNA polymerase II elongation factor ELL2

P42568

Interaction Score

O95402

(UniProtKB/Swiss-Prot/P) Details

Mediator of RNA polymerase II transcription subunit 26

P42568

Interaction Score

0.999

Q9H6A0

(UniProtKB/Swiss-Prot/P) Details

DENN domain-containing protein 2D

P42568

Interaction Score

0.999

Q6W2J9

(UniProtKB/Swiss-Prot/P) Details

BCL-6 corepressor

P42568

Interaction Score

0.999

Q5RL73

(UniProtKB/Swiss-Prot/P) Details

RNA-binding protein 48

P42568

Interaction Score

0.999

P51825

(UniProtKB/Swiss-Prot/P) Details

AF4/FMR2 family member 1

P42568

Interaction Score

0.999

Q7Z3I7

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein 572

P42568

Interaction Score

0.999

Q00534

(UniProtKB/Swiss-Prot/P) Details

Cyclin-dependent kinase 6

P42568

Interaction Score

0.999

Q92624

(UniProtKB/Swiss-Prot/P) Details

Amyloid protein-binding protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Unknown: non-traceable author statement	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Unknown: non-traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Cytoplasmic vesicle membrane (GO:0030659)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.999	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.999	Experimental: experimental	Organelle	PubMed
Cytosol	Microtubule associated complex (GO:0005875)	0.999	Unknown: traceable author statement	GO	PubMed
Cytosol	Microtubule (GO:0005874)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	eSLDB	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

P42568

Interaction Score

0.998

P32121

(UniProtKB/Swiss-Prot/P) Details

Beta-arrestin-2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Coated pit (GO:0005905)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Unknown: traceable author statement	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.972	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endocytic vesicle (GO:0030139)	0.972	Experimental: inferred from direct assay	GO	PubMed
Membrane	Dendritic spine (GO:0043197)	0.99	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic density (GO:0014069)	0.99	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.99	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.99	Experimental: experimental	Organelle	PubMed
Membrane	Basolateral plasma membrane (GO:0016323)	0.99	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic membrane (GO:0045211)	0.99	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P42568

Interaction Score

0.998

Q8NCB2

(UniProtKB/Swiss-Prot/P) Details

CaM kinase-like vesicle-associated protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular (GO:0005622)	0.998	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Cytoplasmic vesicle membrane (GO:0030659)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.96	Experimental: experimental	MatrixDB	PubMed
Extracellular	Intercellular bridge (GO:0045171)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Plasma membrane (GO:0005886)	0.3	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P42568

Interaction Score

0.994

Q5S007

(UniProtKB/Swiss-Prot/P) Details

Leucine-rich repeat serine/threonine-protein kinase 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Neuronal cell body (GO:0043025)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Perikaryon (GO:0043204)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Intracellular (GO:0005622)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Cytosol	Inclusion body (GO:0016234)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial matrix (GO:0005759)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Mitochondrion	Mitochondrial membrane (GO:0031966)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	External side of mitochondrial outer membrane (GO:0032473)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Mitochondrion	Mitochondrial outer membrane (GO:0005741)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Golgi-associated vesicle (GO:0005798)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Trans-Golgi network (GO:0005802)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Multivesicular body, internal vesicle (GO:0097487)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Amphisome (GO:0044753)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Lysosome (GO:0005764)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Synaptic vesicle membrane (GO:0030672)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Growth cone (GO:0030426)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Microvillus (GO:0005902)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Neuron projection (GO:0043005)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Dendrite (GO:0030425)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Dendrite cytoplasm (GO:0032839)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Axon (GO:0030424)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.86	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Terminal button (GO:0043195)	1	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P42568

Interaction Score

0.994

P05067

(UniProtKB/Swiss-Prot/P) Details

Amyloid-beta A4 protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Cell surface (GO:0009986)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Coated pit (GO:0005905)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Apical part of cell (GO:0045177)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: experimental	eSLDB	PubMed
Nucleus	Nuclear envelope lumen (GO:0005641)	0.96	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Rough endoplasmic reticulum (GO:0005791)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Smooth endoplasmic reticulum (GO:0005790)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum lumen (GO:0005788)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi lumen (GO:0005796)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Trans-Golgi network membrane (GO:0032588)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	1	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endosome (GO:0005768)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endosome lumen (GO:0031904)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Lysosome (GO:0005764)	1	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Platelet alpha granule lumen (GO:0031093)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	ER to Golgi transport vesicle (GO:0030134)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Spindle midzone (GO:0051233)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Astrocyte projection (GO:0097449)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendritic shaft (GO:0043198)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Dendritic spine (GO:0043197)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Axon (GO:0030424)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Main axon (GO:0044304)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Ciliary rootlet (GO:0035253)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.98	Experimental: experimental	eSLDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.98	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.98	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.98	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Membrane raft (GO:0045121)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: pTarget method	LOCATE	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Receptor complex (GO:0043235)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Vesicle (GO:0031982)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Cell-cell junction (GO:0005911)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Synapse (GO:0045202)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Neuromuscular junction (GO:0031594)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Presynaptic active zone (GO:0048786)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P42568

Interaction Score

0.994

P68104

(UniProtKB/Swiss-Prot/P) Details

Elongation factor 1-alpha 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Eukaryotic translation elongation factor 1 complex (GO:0005853)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	0.96	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Secretory granule lumen (GO:0034774)	0.3	Unknown: traceable author statement	GO	PubMed
Cytosol	Cortical actin cytoskeleton (GO:0030864)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Ruffle membrane (GO:0032587)	0.994	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.902	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.902	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.902	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.994	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.994	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.994	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

P42568

Interaction Score

0.994

Q13085

(UniProtKB/Swiss-Prot/P) Details

Acetyl-CoA carboxylase 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.91	Predicted: pTarget method	LOCATE	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.91	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Fibrillar center (GO:0001650)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Fibrillar center (GO:0001650)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P42568

Interaction Score

0.991

Q9HCM4

(UniProtKB/Swiss-Prot/P) Details

Band 4.1-like protein 5

P42568

Interaction Score

0.99

Q68DZ5

(UniProtKB/TrEmbl/P) Details

cDNA FLJ58316, highly similar to Beta-arrestin-2

P42568

Interaction Score

0.987

Q92838

(UniProtKB/Swiss-Prot/P) Details

Ectodysplasin-A

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Apical part of cell (GO:0045177)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Lipid particle (GO:0005811)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Lipid particle (GO:0005811)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.79	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Extracellular	Extracellular region (GO:0005576)	0.971	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.971	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.971	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Collagen (GO:0005581)	0.971	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Membrane (GO:0016020)	0.99	Unknown: traceable author statement	GO	PubMed
Membrane	Membrane (GO:0016020)	0.99	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.99	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.99	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.99	Experimental: experimental	Organelle	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	0.99	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P42568

Interaction Score

0.987

Q8IZU1

(UniProtKB/Swiss-Prot/P) Details

Protein FAM9A

P42568

Interaction Score

0.98

P14625

(UniProtKB/Swiss-Prot/P) Details

Endoplasmin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Midbody (GO:0030496)	0.986	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Endomembrane system (GO:0012505)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.86	Unknown: HDA	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.86	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum chaperone complex (GO:0034663)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum lumen (GO:0005788)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endocytic vesicle lumen (GO:0071682)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Melanosome (GO:0042470)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.98	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.98	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.98	Unknown: HDA	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.98	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.986	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.986	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.986	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.986	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P42568

Interaction Score

0.973

Q8NAP7

(UniProtKB/TrEmbl/P) Details

cDNA FLJ35008 fis, clone OCBBF2012191, highly similar to LAF-4 PROTEIN

P42568

Interaction Score

0.97

P48426

(UniProtKB/Swiss-Prot/P) Details

Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.79	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Autophagic vacuole (GO:0005776)	0.998	Experimental: inferred from mutant phenotype	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.86	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P42568

Interaction Score

0.96

B3KXD6

(UniProtKB/TrEmbl/P) Details

Pescadillo homolog 1, containing BRCT domain (Zebrafish), isoform CRA_b

P42568

Interaction Score

0.958

P55198

(UniProtKB/Swiss-Prot/P) Details

Protein AF-17

P42568

Interaction Score

0.957

Q9Y343

(UniProtKB/Swiss-Prot/P) Details

Sorting nexin-24

P42568

Interaction Score

0.938

B0QZ35

(UniProtKB/TrEmbl/P) Details

NAD-dependent protein deacetylase sirtuin-1

P42568

Interaction Score

0.938

E9PC49

(UniProtKB/TrEmbl/P) Details

NAD-dependent protein deacetylase sirtuin-1

P42568

Interaction Score

0.938

Q59EM5

(UniProtKB/TrEmbl/P) Details

Arrestin beta 2 isoform 1 variant

P42568

Interaction Score

0.902

P13639

(UniProtKB/Swiss-Prot/P) Details

Elongation factor 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Aggresome (GO:0016235)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Polysomal ribosome (GO:0042788)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.3	Unknown: HDA	GO	PubMed
Secretory-pathway	Secretory granule lumen (GO:0034774)	0.3	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.972	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.972	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.972	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.997	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.997	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane raft (GO:0045121)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.997	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.997	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Synapse (GO:0045202)	0.997	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P42568

Interaction Score

0.875

Q5VTE0

(UniProtKB/Swiss-Prot/P) Details

Putative elongation factor 1-alpha-like 3

P42568

Interaction Score

0.852

P21246

(UniProtKB/Swiss-Prot/P) Details

Pleiotrophin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.998	Experimental: experimental	eSLDB	PubMed
Membrane	Cell surface (GO:0009986)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.8	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.998	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.998	Experimental: experimental	Human Proteinpedia	PubMed
Extracellular	Extracellular region (GO:0005576)	0.998	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.998	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.998	Experimental: experimental	MatrixDB	PubMed
Extracellular	Basement membrane (GO:0005604)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Membrane (GO:0016020)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Membrane (GO:0016020)	0.931	Experimental: experimental	MatrixDB	PubMed
Membrane	Neuromuscular junction (GO:0031594)	0.931	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

P42568

Interaction Score

0.806

Q9Y2J2

(UniProtKB/Swiss-Prot/P) Details

Band 4.1-like protein 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.937	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.937	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.937	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Postsynaptic density (GO:0014069)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Juxtaparanode region of axon (GO:0044224)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Paranode region of axon (GO:0033270)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Axolemma (GO:0030673)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Cell-cell junction (GO:0005911)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

P42568

Interaction Score

0.8

E9PR89

(UniProtKB/TrEmbl/P) Details

Non-specific serine/threonine protein kinase

P42568

Interaction Score

0.8

Q59EQ6

(UniProtKB/TrEmbl/P) Details

Myeloid/lymphoid or mixed-lineage leukemia translocated to, 10 isoform a variant

P42568

Interaction Score

0.8

A0A2R8Y212

(UniProtKB/TrEmbl/P) Details

Chromodomain-helicase-DNA-binding protein 4

P42568

Interaction Score

0.8

A0A2R8Y5J0

(UniProtKB/TrEmbl/P) Details

Chromodomain-helicase-DNA-binding protein 4

P42568

Interaction Score

0.8

A0A2R8YFK9

(UniProtKB/TrEmbl/P) Details

Chromodomain-helicase-DNA-binding protein 4

P42568

Interaction Score

0.8

F5GWX5

(UniProtKB/TrEmbl/P) Details

Chromodomain-helicase-DNA-binding protein 4

P42568

Interaction Score

0.8

A0A087WW39

(UniProtKB/TrEmbl/P) Details

Protein AF-17

P42568

Interaction Score

0.776

Q9NXW9

(UniProtKB/Swiss-Prot/P) Details

Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4

P42568

Interaction Score

0.74

P21741

(UniProtKB/Swiss-Prot/P) Details

Midkine

P42568

Interaction Score

0.7

Q59FW6

(UniProtKB/TrEmbl/P) Details

Elongation factor, RNA polymerase II, 2 variant

P42568

Interaction Score

0.7

Q7Z656

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein DKFZp779C185

P42568

Interaction Score

0.7

Q9NYS3

(UniProtKB/TrEmbl/P) Details

Apoptosis-related protein PNAS-3

P42568

Interaction Score

0.688

Q6IPS9

(UniProtKB/TrEmbl/P) Details

Elongation factor 1-alpha

P42568

Interaction Score

0.688

A0A0A0MRG2

(UniProtKB/TrEmbl/P) Details

Amyloid-beta A4 protein

P42568

Interaction Score

0.688

E9PG40

(UniProtKB/TrEmbl/P) Details

Amyloid-beta A4 protein

P42568

Interaction Score

0.688

K7ENA6

(UniProtKB/TrEmbl/P) Details

Beta-arrestin-2

P42568

Interaction Score

0.602

Q7Z5W8

(UniProtKB/TrEmbl/P) Details

ACACA protein

P42568

Interaction Score

0.602

Q6N002

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein DKFZp686E10210

P42568

Interaction Score

0.602

A0A0A0MRA8

(UniProtKB/TrEmbl/P) Details

Band 4.1-like protein 3

P42568

Interaction Score

0.258

Q8TDL5

(UniProtKB/Swiss-Prot/P) Details

BPI fold-containing family B member 1

P42568

Interaction Score

A8K968

(UniProtKB/TrEmbl/P) Details

Band 4.1-like protein 3

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P42568

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

P42568

O14980

Exportin-1

Localizations:

Interaction Source Database:

Interaction Source Publication:

P42568

Q96EB6

NAD-dependent protein deacetylase sirtuin-1

Localizations:

Interaction Source Database:

Interaction Source Publication:

P42568

Q9NQT5

Exosome complex component RRP40

Localizations:

Interaction Source Database:

Interaction Source Publication:

P42568

Q5UIP0

Telomere-associated protein RIF1

Localizations:

Interaction Source Database:

Interaction Source Publication:

P42568

O00541

Pescadillo homolog

Localizations:

Interaction Source Database:

Interaction Source Publication:

P42568

Q03164

Histone-lysine N-methyltransferase 2A

Localizations:

Interaction Source Database:

Interaction Source Publication:

P42568

Q99496

E3 ubiquitin-protein ligase RING2

Localizations:

Interaction Source Database:

Interaction Source Publication:

P42568

P51826

AF4/FMR2 family member 3

Localizations:

Interaction Source Database:

Interaction Source Publication:

P42568

Q14839

Chromodomain-helicase-DNA-binding protein 4

Localizations:

Interaction Source Database:

Interaction Source Publication:

P42568

Q96JC9

ELL-associated factor 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

P42568

Q03111

Protein ENL

Localizations:

Interaction Source Database:

Interaction Source Publication:

P42568

O60583

Cyclin-T2

Localizations:

Interaction Source Database:

Interaction Source Publication:

P42568