P42681

Tyrosine-protein kinase TXK    //   UniProt Profile 

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Species

 H. sapiens

Number of Interactions

 28 / 28

Average Interaction Score

 0.905

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.996 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.996 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.996 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.996 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.8 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Extrinsic to internal side of plasma membrane (GO:0031234) 0.91 Predicted: inferred from biological aspect of ancestor GO PubMed 

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

P42681

Interaction Score
1

P06241

(UniProtKB/Swiss-Prot/P) Details

Tyrosine-protein kinase Fyn

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cell body (GO:0044297) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Perinuclear endoplasmic reticulum (GO:0097038) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: inferred from sequence or structural similarity GO PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Predicted: inferred from sequence or structural similarity GO PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Experimental: experimental Human Proteinpedia PubMed 
Secretory-pathway Endosome (GO:0005768) 0.8 Experimental: inferred from direct assay GO PubMed 
Cytosol Actin filament (GO:0005884) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Glial cell projection (GO:0097386) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Dendrite (GO:0030425) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Postsynaptic density (GO:0014069) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane raft (GO:0045121) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Extrinsic to internal side of plasma membrane (GO:0031234) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed 

P42681

Interaction Score
1

P62993

(UniProtKB/Swiss-Prot/P) Details

Growth factor receptor-bound protein 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.999 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.999 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleolus (GO:0005730) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Signalosome (GO:0008180) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Endosome (GO:0005768) 0.86 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.971 Unknown: traceable author statement GO PubMed 
Membrane Extrinsic to internal side of plasma membrane (GO:0031234) 0.971 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Grb2-EGFR complex (GO:0070436) 0.971 Experimental: inferred from direct assay GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.999 Unknown: HDA GO PubMed 
Cytosol Vesicle membrane (GO:0012506) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Membrane Cell-cell junction (GO:0005911) 0.971 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P42681

Interaction Score
1

P12931

(UniProtKB/Swiss-Prot/P) Details

Proto-oncogene tyrosine-protein kinase Src

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 1 Unknown: inferred from electronic annotation GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.96 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrial inner membrane (GO:0005743) 0.96 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Late endosome (GO:0005770) 0.8 Experimental: inferred from direct assay GO PubMed 
Cytosol Lysosome (GO:0005764) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Podosome (GO:0002102) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Actin filament (GO:0005884) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Ruffle membrane (GO:0032587) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Neuron projection (GO:0043005) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Postsynaptic density (GO:0014069) 1 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Extrinsic to internal side of plasma membrane (GO:0031234) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Caveola (GO:0005901) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed 

P42681

Interaction Score
1

P46108

(UniProtKB/Swiss-Prot/P) Details

Adapter molecule crk

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.978 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.978 Unknown: inferred by curator GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.978 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.978 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 0.958 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 0.958 Experimental: experimental Organelle PubMed 
Nucleus Macromolecular complex (GO:0032991) 0.958 Predicted: inferred from physical interaction GO PubMed 
Cytosol Actin cytoskeleton (GO:0015629) 0.978 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane raft (GO:0045121) 0.971 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.971 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.971 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Plasma membrane (GO:0005886) 0.971 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.978 Unknown: HDA GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P42681

Interaction Score
1

P04626

(UniProtKB/Swiss-Prot/P) Details

Receptor tyrosine-protein kinase erbB-2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Myelin sheath (GO:0043209) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytosol (GO:0005829) 0.972 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.972 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 0.972 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.8 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endosome membrane (GO:0010008) 0.8 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Unknown: non-traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Receptor complex (GO:0043235) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Apical plasma membrane (GO:0016324) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Basolateral plasma membrane (GO:0016323) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed 

P42681

Interaction Score
0.999

O14544

(UniProtKB/Swiss-Prot/P) Details

Suppressor of cytokine signaling 6

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.991 Unknown: traceable author statement GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.991 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytoplasm (GO:0005737) 0.991 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.991 Unknown: traceable author statement GO PubMed 
Cytosol Cytosol (GO:0005829) 0.991 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.982 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.982 Predicted: pTarget method LOCATE PubMed 
Nucleus Nuclear speck (GO:0016607) 0.982 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Immunological synapse (GO:0001772) 0.8 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P42681

Interaction Score
0.998

Q8IXH7

(UniProtKB/Swiss-Prot/P) Details

Negative elongation factor C/D

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Unknown: traceable author statement GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nuclear body (GO:0016604) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus NELF complex (GO:0032021) 1 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.3 Unknown: HDA GO PubMed 

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed 

P42681

Interaction Score
0.997

P21860

(UniProtKB/Swiss-Prot/P) Details

Receptor tyrosine-protein kinase erbB-3

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.8 Experimental: experimental eSLDB PubMed 
Cytosol Intracellular (GO:0005622) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Actin cytoskeleton (GO:0015629) 0.86 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.96 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular space (GO:0005615) 0.96 Experimental: inferred from direct assay GO PubMed 
Membrane Membrane (GO:0016020) 1 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Experimental: experimental eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 1 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: pTarget method LOCATE PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Lateral plasma membrane (GO:0016328) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Integral to plasma membrane (GO:0005887) 1 Unknown: traceable author statement GO PubMed 
Membrane Receptor complex (GO:0043235) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Apical plasma membrane (GO:0016324) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Basolateral plasma membrane (GO:0016323) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed 

P42681

Interaction Score
0.996

P08581

(UniProtKB/Swiss-Prot/P) Details

Hepatocyte growth factor receptor

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Cell surface (GO:0009986) 1 Unknown: HDA GO PubMed 
Cytosol Intracellular (GO:0005622) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytosol (GO:0005829) 0.86 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.86 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 1 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Unknown: non-traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Integral to plasma membrane (GO:0005887) 1 Unknown: traceable author statement GO PubMed 
Membrane Basal plasma membrane (GO:0009925) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P42681

Interaction Score
0.995

P16410

(UniProtKB/Swiss-Prot/P) Details

Cytotoxic T-lymphocyte protein 4

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.988 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 0.8 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.988 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Clathrin-coated endocytic vesicle (GO:0045334) 0.988 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to membrane (GO:0016021) 0.999 Experimental: experimental eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.999 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.999 Experimental: experimental Organelle PubMed 
Membrane External side of plasma membrane (GO:0009897) 0.999 Experimental: inferred from direct assay GO PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.999 Experimental: inferred from mutant phenotype GO PubMed 

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed 

P42681

Interaction Score
0.995

Q13094

(UniProtKB/Swiss-Prot/P) Details

Lymphocyte cytosolic protein 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
N/A TCR signalosome (GO:0036398) 0.8 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.996 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.996 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 0.996 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.996 Experimental: inferred from direct assay GO PubMed 
Membrane Cell-cell junction (GO:0005911) 0.3 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed 

P42681

Interaction Score
0.995

Q7Z7G1

(UniProtKB/Swiss-Prot/P) Details

Cytokine-dependent hematopoietic cell linker

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Intracellular (GO:0005622) 0.991 Unknown: non-traceable author statement GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.991 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.991 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 0.991 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.991 Unknown: unspecified method The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: pTarget method LOCATE PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed 

P42681

Interaction Score
0.985

P10721

(UniProtKB/Swiss-Prot/P) Details

Mast/stem cell growth factor receptor Kit

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Mast cell granule (GO:0042629) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Acrosomal vesicle (GO:0001669) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.96 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular space (GO:0005615) 0.96 Experimental: inferred from direct assay GO PubMed 
Membrane Membrane (GO:0016020) 1 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Internal side of plasma membrane (GO:0009898) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane External side of plasma membrane (GO:0009897) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Cell-cell junction (GO:0005911) 1 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P42681

Interaction Score
0.984

O60496

(UniProtKB/Swiss-Prot/P) Details

Docking protein 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.987 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.987 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 0.987 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.987 Unknown: traceable author statement GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P42681

Interaction Score
0.982

O43639

(UniProtKB/Swiss-Prot/P) Details

Cytoplasmic protein NCK2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.979 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.979 Unknown: non-traceable author statement GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.979 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.979 Unknown: traceable author statement GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.8 Experimental: inferred from direct assay GO PubMed 
Membrane Postsynaptic density (GO:0014069) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Vesicle membrane (GO:0012506) 0.979 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P42681

Interaction Score
0.98

J3QLU9

(UniProtKB/TrEmbl/P) Details

Receptor protein-tyrosine kinase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P42681

Interaction Score
0.977

P51681

(UniProtKB/Swiss-Prot/P) Details

C-C chemokine receptor type 5

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Cell surface (GO:0009986) 0.999 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.3 Unknown: traceable author statement GO PubMed 
Secretory-pathway Endosome (GO:0005768) 0.8 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.999 Experimental: experimental eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.999 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.999 Experimental: experimental Organelle PubMed 
Membrane External side of plasma membrane (GO:0009897) 0.999 Experimental: inferred from direct assay GO PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.999 Unknown: traceable author statement GO PubMed 

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed 

P42681

Interaction Score
0.975

Q96MU7

(UniProtKB/Swiss-Prot/P) Details

YTH domain-containing protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nuclear speck (GO:0016607) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.96 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed 

P42681

Interaction Score
0.949

Q9Y2P0

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein 835

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.937 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.937 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.937 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Microtubule cytoskeleton (GO:0015630) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P42681

Interaction Score
0.945

F5H1T4

(UniProtKB/TrEmbl/P) Details

Receptor tyrosine-protein kinase erbB-2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Plasma membrane (GO:0005886) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P42681

Interaction Score
0.939

Q9NYW8

(UniProtKB/Swiss-Prot/P) Details

RB-associated KRAB zinc finger protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.999 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.999 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 0.999 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 0.999 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.999 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P42681

Interaction Score
0.937

Q3KQV3

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein 792

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.992 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nuclear body (GO:0016604) 0.992 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P42681

Interaction Score
0.8

Q9H2S9

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein Eos

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nuclear body (GO:0016604) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear body (GO:0016604) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Macromolecular complex (GO:0032991) 1 Experimental: inferred from mutant phenotype GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P42681

Interaction Score
0.793

Q9GZV8

(UniProtKB/Swiss-Prot/P) Details

PR domain zinc finger protein 14

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.992 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.992 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.992 Unknown: unspecified method The Human Protein Atlas PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P42681

Interaction Score
0.776

Q96SQ5

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein 587

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.971 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.971 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.971 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.971 Unknown: unspecified method The Human Protein Atlas PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P42681

Interaction Score
0.697

Q5UBZ3

(UniProtKB/TrEmbl/P) Details

SH2 domain containing adapter protein 2 transcript variant 3

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed 

P42681

Interaction Score
0.64

X5DNK3

(UniProtKB/TrEmbl/P) Details

Receptor protein-tyrosine kinase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P42681

Interaction Score
0

Q5JST6

(UniProtKB/Swiss-Prot/P) Details

EF-hand domain-containing family member C2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

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ComPPI is published in Nucleic Acids Research Database Issue 2015