P43320

Beta-crystallin B2 // UniProt Profile

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Species	H. sapiens
Number of Interactions	11 / 15
Average Interaction Score	0.723

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

P43320

Interaction Score

0.94

P02511

(UniProtKB/Swiss-Prot/P) Details

Alpha-crystallin B chain

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	0.976	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Myelin sheath (GO:0043209)	0.976	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Perikaryon (GO:0043204)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.79	Unknown: inferred from electronic annotation	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.79	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.998	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Z disc (GO:0030018)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	M band (GO:0031430)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Actin filament bundle (GO:0032432)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendritic spine (GO:0043197)	0.976	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic density (GO:0014069)	0.976	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Axon (GO:0030424)	0.976	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.976	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Synaptic membrane (GO:0097060)	0.976	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

HPRD, IntAct, BioGRID

Interaction Source Publication:

PubMed

P43320

Interaction Score

0.938

P02489

(UniProtKB/Swiss-Prot/P) Details

Alpha-crystallin A chain

P43320

Interaction Score

0.93

P04792

(UniProtKB/Swiss-Prot/P) Details

Heat shock protein beta-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Proteasome complex (GO:0000502)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Z disc (GO:0030018)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Spindle (GO:0005819)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular space (GO:0005615)	0.86	Unknown: HDA	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.86	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.98	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.98	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.98	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.98	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct, HPRD, BioGRID

Interaction Source Publication:

PubMed

P43320

Interaction Score

0.924

A0A140G945

(UniProtKB/Swiss-Prot/P) Details

Alpha-crystallin A2 chain

P43320

Interaction Score

0.891

P07315

(UniProtKB/Swiss-Prot/P) Details

Gamma-crystallin C

P43320

Interaction Score

0.86

P05813

(UniProtKB/Swiss-Prot/P) Details

Beta-crystallin A3

P43320

Interaction Score

0.786

P61968

(UniProtKB/Swiss-Prot/P) Details

LIM domain transcription factor LMO4

P43320

Interaction Score

0.56

A0A024R3B9

(UniProtKB/TrEmbl/P) Details

Alpha-crystallin B chain

P43320

Interaction Score

0.56

P53673

(UniProtKB/Swiss-Prot/P) Details

Beta-crystallin A4

P43320

Interaction Score

0.56

P53672

(UniProtKB/Swiss-Prot/P) Details

Beta-crystallin A2

P43320

Interaction Score

P30301

(UniProtKB/Swiss-Prot/P) Details

Lens fiber major intrinsic protein

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P43320

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

P43320

P02511

Alpha-crystallin B chain

Localizations:

Interaction Source Database:

Interaction Source Publication:

P43320

P02489

Alpha-crystallin A chain

Localizations:

Interaction Source Database:

Interaction Source Publication:

P43320

P04792

Heat shock protein beta-1

Localizations:

Interaction Source Database:

Interaction Source Publication:

P43320

A0A140G945

Alpha-crystallin A2 chain

Localizations:

Interaction Source Database:

Interaction Source Publication:

P43320

P07315

Gamma-crystallin C

Localizations:

Interaction Source Database:

Interaction Source Publication:

P43320

P05813

Beta-crystallin A3

Localizations:

Interaction Source Database:

Interaction Source Publication:

P43320

P61968

LIM domain transcription factor LMO4

Localizations:

Interaction Source Database:

Interaction Source Publication:

P43320

A0A024R3B9

Alpha-crystallin B chain

Localizations:

Interaction Source Database:

Interaction Source Publication:

P43320

P53673

Beta-crystallin A4

Localizations:

Interaction Source Database:

Interaction Source Publication:

P43320

P53672

Beta-crystallin A2

Localizations:

Interaction Source Database:

Interaction Source Publication:

P43320

P30301

Lens fiber major intrinsic protein

Localizations:

Interaction Source Database:

Interaction Source Publication: