P48645

Neuromedin-U // UniProt Profile

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Species	H. sapiens
Number of Interactions	30 / 34
Average Interaction Score	0.873

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.8	Experimental: experimental	eSLDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.937	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.937	Predicted: pTarget method	LOCATE	PubMed
Extracellular	Extracellular region (GO:0005576)	0.937	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Membrane (GO:0016020)	0.86	Experimental: experimental	MatrixDB	PubMed
Membrane	Terminal button (GO:0043195)	0.86	Unknown: inferred from electronic annotation	GO	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

P48645

Interaction Score

0.996

P20036

(UniProtKB/Swiss-Prot/P) Details

HLA class II histocompatibility antigen, DP alpha 1 chain

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	0.994	Experimental: inferred from mutant phenotype	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Integral to lumenal side of endoplasmic reticulum membrane (GO:0071556)	0.942	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.942	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Trans-Golgi network membrane (GO:0032588)	0.942	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endosome membrane (GO:0010008)	0.942	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Lysosome (GO:0005764)	0.992	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Lysosomal membrane (GO:0005765)	0.992	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endocytic vesicle membrane (GO:0030666)	0.942	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	ER to Golgi transport vesicle membrane (GO:0012507)	0.942	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Clathrin-coated endocytic vesicle membrane (GO:0030669)	0.942	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Transport vesicle membrane (GO:0030658)	0.942	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.994	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.994	Unknown: traceable author statement	GO	PubMed
Membrane	MHC class II protein complex (GO:0042613)	0.994	Experimental: inferred from direct assay	GO	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	0.994	Unknown: non-traceable author statement	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P48645

Interaction Score

0.992

Q6UXL0

(UniProtKB/Swiss-Prot/P) Details

Interleukin-20 receptor subunit beta

P48645

Interaction Score

0.989

Q9H8J5

(UniProtKB/Swiss-Prot/P) Details

MANSC domain-containing protein 1

P48645

Interaction Score

0.985

O75752

(UniProtKB/Swiss-Prot/P) Details

UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1

P48645

Interaction Score

0.983

P08709

(UniProtKB/Swiss-Prot/P) Details

Coagulation factor VII

P48645

Interaction Score

0.983

Q8N6Y1

(UniProtKB/Swiss-Prot/P) Details

Protocadherin-20

P48645

Interaction Score

0.982

Q9UN74

(UniProtKB/Swiss-Prot/P) Details

Protocadherin alpha-4

P48645

Interaction Score

0.972

Q49AT3

(UniProtKB/TrEmbl/P) Details

Hexosyltransferase

P48645

Interaction Score

0.972

Q7L9G8

(UniProtKB/TrEmbl/P) Details

Hexosyltransferase

P48645

Interaction Score

0.972

Q8TDY1

(UniProtKB/TrEmbl/P) Details

Hexosyltransferase

P48645

Interaction Score

0.97

Q9NQZ7

(UniProtKB/Swiss-Prot/P) Details

Ectonucleoside triphosphate diphosphohydrolase 7

P48645

Interaction Score

0.964

Q7Z3S9

(UniProtKB/Swiss-Prot/P) Details

Notch homolog 2 N-terminal-like protein

P48645

Interaction Score

0.964

Q9HB89

(UniProtKB/Swiss-Prot/P) Details

Neuromedin-U receptor 1

P48645

Interaction Score

0.963

Q13424

(UniProtKB/Swiss-Prot/P) Details

Alpha-1-syntrophin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular (GO:0005622)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.999	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.99	Experimental: experimental	eSLDB	PubMed
Membrane	Syntrophin complex (GO:0016013)	0.99	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.99	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Sarcolemma (GO:0042383)	0.99	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Lateral plasma membrane (GO:0016328)	0.99	Unknown: traceable author statement	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.99	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Neuromuscular junction (GO:0031594)	0.99	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P48645

Interaction Score

0.962

Q9GZQ4

(UniProtKB/Swiss-Prot/P) Details

Neuromedin-U receptor 2

P48645

Interaction Score

0.959

Q63HR2

(UniProtKB/Swiss-Prot/P) Details

Tensin-2

P48645

Interaction Score

0.959

Q9NU53

(UniProtKB/Swiss-Prot/P) Details

Glycoprotein integral membrane protein 1

P48645

Interaction Score

0.939

Q9UBM8

(UniProtKB/Swiss-Prot/P) Details

Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C

P48645

Interaction Score

0.863

A8MQ03

(UniProtKB/Swiss-Prot/P) Details

Cysteine-rich tail protein 1

P48645

Interaction Score

0.849

P26371

(UniProtKB/Swiss-Prot/P) Details

Keratin-associated protein 5-9

P48645

Interaction Score

0.849

Q9BYP8

(UniProtKB/Swiss-Prot/P) Details

Keratin-associated protein 17-1

P48645

Interaction Score

0.849

Q07627

(UniProtKB/Swiss-Prot/P) Details

Keratin-associated protein 1-1

P48645

Interaction Score

0.849

Q9BYS1

(UniProtKB/Swiss-Prot/P) Details

Keratin-associated protein 1-5

P48645

Interaction Score

0.808

Q9UHG0

(UniProtKB/Swiss-Prot/P) Details

Doublecortin domain-containing protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.94	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Mitotic spindle (GO:0072686)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Axoneme (GO:0005930)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cilium (GO:0005929)	0.94	Experimental: inferred from direct assay	GO	PubMed
Membrane	Kinocilium (GO:0060091)	0.94	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P48645

Interaction Score

0.783

Q59H34

(UniProtKB/TrEmbl/P) Details

Protocadherin alpha 4 isoform 1 variant

P48645

Interaction Score

0.776

O76011

(UniProtKB/Swiss-Prot/P) Details

Keratin, type I cuticular Ha4

P48645

Interaction Score

0.75

B3KTQ4

(UniProtKB/TrEmbl/P) Details

Hexosyltransferase

P48645

Interaction Score

0.656

P60328

(UniProtKB/Swiss-Prot/P) Details

Keratin-associated protein 12-3

P48645

Interaction Score

0.656

P60371

(UniProtKB/Swiss-Prot/P) Details

Keratin-associated protein 10-6

P48645

Interaction Score

F5H8B0

(UniProtKB/TrEmbl/P) Details

Coagulation factor VII

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P48645

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

P48645

P20036

HLA class II histocompatibility antigen, DP alpha 1 chain

Localizations:

Interaction Source Database:

Interaction Source Publication:

P48645

Q6UXL0

Interleukin-20 receptor subunit beta

Localizations:

Interaction Source Database:

Interaction Source Publication:

P48645

Q9H8J5

MANSC domain-containing protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

P48645

O75752

UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

P48645

P08709

Coagulation factor VII

Localizations:

Interaction Source Database:

Interaction Source Publication:

P48645

Q8N6Y1

Protocadherin-20

Localizations:

Interaction Source Database:

Interaction Source Publication:

P48645

Q9UN74

Protocadherin alpha-4

Localizations:

Interaction Source Database:

Interaction Source Publication:

P48645

Q49AT3

Hexosyltransferase

Localizations:

Interaction Source Database:

Interaction Source Publication:

P48645

Q7L9G8

Hexosyltransferase

Localizations:

Interaction Source Database:

Interaction Source Publication:

P48645

Q8TDY1

Hexosyltransferase

Localizations:

Interaction Source Database:

Interaction Source Publication:

P48645

Q9NQZ7

Ectonucleoside triphosphate diphosphohydrolase 7

Localizations:

Interaction Source Database:

Interaction Source Publication:

P48645

Q7Z3S9

Notch homolog 2 N-terminal-like protein

Localizations:

Interaction Source Database:

Interaction Source Publication:

P48645