P53370

Nucleoside diphosphate-linked moiety X motif 6 // UniProt Profile

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Species	H. sapiens
Number of Interactions	18 / 21
Average Interaction Score	0.76

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
N/A	Cellular component (GO:0005575)	0.3	Unknown: no biological data available	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.79	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

P53370

Interaction Score

0.984

P22314

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin-like modifier-activating enzyme 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Rough endoplasmic reticulum membrane (GO:0030867)	0.96	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endosome membrane (GO:0010008)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Lysosomal membrane (GO:0005765)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Heterochromatin (GO:0000792)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Desmosome (GO:0030057)	0.8	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P53370

Interaction Score

0.958

P61088

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin-conjugating enzyme E2 N

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Ubiquitin ligase complex (GO:0000151)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	UBC13-MMS2 complex (GO:0031372)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	UBC13-UEV1A complex (GO:0035370)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Fibrillar center (GO:0001650)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Fibrillar center (GO:0001650)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P53370

Interaction Score

0.958

Q13404

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin-conjugating enzyme E2 variant 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Ubiquitin ligase complex (GO:0000151)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Ubiquitin conjugating enzyme complex (GO:0031371)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	UBC13-UEV1A complex (GO:0035370)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Membrane (GO:0016020)	0.94	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P53370

Interaction Score

0.956

Q9BUE6

(UniProtKB/Swiss-Prot/P) Details

Iron-sulfur cluster assembly 1 homolog, mitochondrial

P53370

Interaction Score

0.945

Q8IWV8

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase UBR2

P53370

Interaction Score

0.945

P46199

(UniProtKB/Swiss-Prot/P) Details

Translation initiation factor IF-2, mitochondrial

P53370

Interaction Score

0.939

O43583

(UniProtKB/Swiss-Prot/P) Details

Density-regulated protein

P53370

Interaction Score

0.931

Q92686

(UniProtKB/Swiss-Prot/P) Details

Neurogranin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Neuronal cell body (GO:0043025)	0.958	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.958	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.958	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrial membrane (GO:0031966)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Trans-Golgi network transport vesicle membrane (GO:0012510)	0.79	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendritic spine head (GO:0044327)	0.76	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic density (GO:0014069)	0.76	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Axon (GO:0030424)	0.76	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic membrane (GO:0045211)	0.76	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P53370

Interaction Score

0.892

P23378

(UniProtKB/Swiss-Prot/P) Details

Glycine dehydrogenase (decarboxylating), mitochondrial

P53370

Interaction Score

0.866

P0DPB3

(UniProtKB/Swiss-Prot/P) Details

Schwannomin-interacting protein 1

P53370

Interaction Score

0.797

Q53S33

(UniProtKB/Swiss-Prot/P) Details

BolA-like protein 3

P53370

Interaction Score

0.783

Q96EY8

(UniProtKB/Swiss-Prot/P) Details

Cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial

P53370

Interaction Score

0.761

Q8WVY7

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin-like domain-containing CTD phosphatase 1

P53370

Interaction Score

0.756

Q8IYS1

(UniProtKB/Swiss-Prot/P) Details

Peptidase M20 domain-containing protein 2

P53370

Interaction Score

0.658

Q9UJW2

(UniProtKB/Swiss-Prot/P) Details

Tubulointerstitial nephritis antigen

P53370

Interaction Score

0.553

Q6P1N2

(UniProtKB/TrEmbl/P) Details

MTIF2 protein

P53370

Interaction Score

Q6NSC1

(UniProtKB/TrEmbl/P) Details

Tubulointerstitial nephritis antigen

P53370

Interaction Score

Q8N338

(UniProtKB/TrEmbl/P) Details

BOLA3 protein

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P53370

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

P53370

P22314

Ubiquitin-like modifier-activating enzyme 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

P53370

P61088

Ubiquitin-conjugating enzyme E2 N

Localizations:

Interaction Source Database:

Interaction Source Publication:

P53370

Q13404

Ubiquitin-conjugating enzyme E2 variant 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

P53370

Q9BUE6

Iron-sulfur cluster assembly 1 homolog, mitochondrial

Localizations:

Interaction Source Database:

Interaction Source Publication:

P53370

Q8IWV8

E3 ubiquitin-protein ligase UBR2

Localizations:

Interaction Source Database:

Interaction Source Publication:

P53370

P46199

Translation initiation factor IF-2, mitochondrial

Localizations:

Interaction Source Database:

Interaction Source Publication:

P53370

O43583

Density-regulated protein

Localizations:

Interaction Source Database:

Interaction Source Publication:

P53370

Q92686

Neurogranin

Localizations:

Interaction Source Database:

Interaction Source Publication:

P53370

P23378

Glycine dehydrogenase (decarboxylating), mitochondrial

Localizations:

Interaction Source Database:

Interaction Source Publication:

P53370

P0DPB3

Schwannomin-interacting protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

P53370

Q53S33

BolA-like protein 3

Localizations:

Interaction Source Database:

Interaction Source Publication:

P53370

Q96EY8

Cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial

Localizations:

Interaction Source Database:

Interaction Source Publication:

P53370