P54136

Arginine--tRNA ligase, cytoplasmic    //   UniProt Profile 

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Species

 H. sapiens

Number of Interactions

 116 / 162

Average Interaction Score

 0.911

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Aminoacyl-tRNA synthetase multienzyme complex (GO:0017101) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.992 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.992 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Experimental: experimental Human Proteinpedia PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.3 Unknown: HDA GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

P54136

Interaction Score
1

Q16513

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein kinase N2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Midbody (GO:0030496) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cleavage furrow (GO:0032154) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nuclear body (GO:0016604) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Macromolecular complex (GO:0032991) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Intermediate filament cytoskeleton (GO:0045111) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Intermediate filament cytoskeleton (GO:0045111) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Centrosome (GO:0005813) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Lamellipodium (GO:0030027) 1 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Apical junction complex (GO:0043296) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

P35240

(UniProtKB/Swiss-Prot/P) Details

Merlin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cleavage furrow (GO:0032154) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cell body (GO:0044297) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Apical part of cell (GO:0045177) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleolus (GO:0005730) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Early endosome (GO:0005769) 0.8 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Unknown: traceable author statement GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Experimental: experimental Organelle PubMed 
Cytosol Cortical actin cytoskeleton (GO:0030864) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Ruffle membrane (GO:0032587) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Lamellipodium (GO:0030027) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Filopodium membrane (GO:0031527) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Neuron projection (GO:0043005) 1 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 1 Experimental: experimental eSLDB PubMed 
Membrane Membrane (GO:0016020) 1 Unknown: HDA GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Human Proteinpedia PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Vesicle (GO:0031982) 1 Experimental: experimental eSLDB PubMed 
Membrane Adherens junction (GO:0005912) 1 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

O00560

(UniProtKB/Swiss-Prot/P) Details

Syntenin-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Unknown: non-traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nuclear membrane (GO:0031965) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear membrane (GO:0031965) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.931 Experimental: experimental eSLDB PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 0.931 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Melanosome (GO:0042470) 0.931 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Azurophil granule lumen (GO:0035578) 0.931 Unknown: traceable author statement GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Unknown: non-traceable author statement GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Experimental: experimental Organelle PubMed 
Extracellular Extracellular region (GO:0005576) 0.931 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.931 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular space (GO:0005615) 0.931 Unknown: HDA GO PubMed 
Extracellular Blood microparticle (GO:0072562) 0.931 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 1 Experimental: experimental eSLDB PubMed 
Membrane Membrane (GO:0016020) 1 Unknown: non-traceable author statement GO PubMed 
Membrane Membrane (GO:0016020) 1 Experimental: experimental MatrixDB PubMed 
Membrane Membrane raft (GO:0045121) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Interleukin-5 receptor complex (GO:0005895) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 
Membrane Adherens junction (GO:0005912) 1 Unknown: non-traceable author statement GO PubMed 
Membrane Focal adhesion (GO:0005925) 1 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

Q9Y6K9

(UniProtKB/Swiss-Prot/P) Details

NF-kappa-B essential modulator

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Ubiquitin ligase complex (GO:0000151) 1 Predicted: inferred from physical interaction GO PubMed 
Cytosol Intracellular (GO:0005622) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol IkappaB kinase complex (GO:0008385) 1 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 0.997 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.997 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.997 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 0.997 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.997 Unknown: traceable author statement GO PubMed 
Cytosol Mitotic spindle (GO:0072686) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Spindle pole (GO:0000922) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

Q14145

(UniProtKB/Swiss-Prot/P) Details

Kelch-like ECH-associated protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cul3-RING ubiquitin ligase complex (GO:0031463) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Midbody (GO:0030496) 0.8 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.988 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.988 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.988 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Microtubule organizing center (GO:0005815) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Microtubule organizing center (GO:0005815) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Actin filament (GO:0005884) 1 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

O00429

(UniProtKB/Swiss-Prot/P) Details

Dynamin-1-like protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Coated pit (GO:0005905) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.988 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.988 Predicted: PAML algorithm PA-GOSUB PubMed 
Mitochondrion Mitochondrial outer membrane (GO:0005741) 0.988 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Macromolecular complex (GO:0032991) 0.94 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.997 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.997 Experimental: experimental Organelle PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 0.997 Unknown: traceable author statement GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.997 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi membrane (GO:0000139) 0.997 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Peroxisome (GO:0005777) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Synaptic vesicle membrane (GO:0030672) 0.997 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Microtubule (GO:0005874) 1 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.51 Unknown: HDA GO PubMed 
Membrane Cell junction (GO:0030054) 0.51 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

P07437

(UniProtKB/Swiss-Prot/P) Details

Tubulin beta chain

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cell body (GO:0044297) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.972 Unknown: HDA GO PubMed 
Nucleus Nucleus (GO:0005634) 0.972 Experimental: experimental Human Proteinpedia PubMed 
Nucleus Nuclear envelope lumen (GO:0005641) 0.972 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Azurophil granule lumen (GO:0035578) 0.3 Unknown: traceable author statement GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Unknown: traceable author statement GO PubMed 
Cytosol Microtubule cytoskeleton (GO:0015630) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Microtubule (GO:0005874) 1 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.86 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular matrix (GO:0031012) 0.86 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.86 Experimental: experimental MatrixDB PubMed 
Membrane Membrane raft (GO:0045121) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

Q9P2J5

(UniProtKB/Swiss-Prot/P) Details

Leucine--tRNA ligase, cytoplasmic

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Endomembrane system (GO:0012505) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Aminoacyl-tRNA synthetase multienzyme complex (GO:0017101) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear body (GO:0016604) 0.96 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear body (GO:0016604) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.8 Experimental: inferred from direct assay GO PubMed 
Cytosol Lysosome (GO:0005764) 1 Experimental: inferred from mutant phenotype GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed , PubMed 

P54136

Interaction Score
1

Q9NQC7

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin carboxyl-terminal hydrolase CYLD

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Midbody (GO:0030496) 0.96 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 1 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Experimental: experimental Organelle PubMed 
Cytosol Spindle (GO:0005819) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Microtubule organizing center (GO:0005815) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Cilium basal body (GO:0036064) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Centrosome (GO:0005813) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasmic microtubule (GO:0005881) 1 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Extrinsic to internal side of plasma membrane (GO:0031234) 0.96 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

Q99558

(UniProtKB/Swiss-Prot/P) Details

Mitogen-activated protein kinase kinase kinase 14

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Fibrillar center (GO:0001650) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Fibrillar center (GO:0001650) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

O43324

(UniProtKB/Swiss-Prot/P) Details

Eukaryotic translation elongation factor 1 epsilon-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Aminoacyl-tRNA synthetase multienzyme complex (GO:0017101) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleolus (GO:0005730) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

O95793

(UniProtKB/Swiss-Prot/P) Details

Double-stranded RNA-binding protein Staufen homolog 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cell body (GO:0044297) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Neuronal cell body (GO:0043025) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytoplasmic stress granule (GO:0010494) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.994 Experimental: experimental eSLDB PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.994 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.994 Experimental: experimental Organelle PubMed 
Secretory-pathway Rough endoplasmic reticulum (GO:0005791) 0.994 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Experimental: experimental Organelle PubMed 
Cytosol Microtubule associated complex (GO:0005875) 1 Unknown: traceable author statement GO PubMed 
Membrane Dendrite (GO:0030425) 0.972 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.972 Unknown: HDA GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.972 Experimental: inferred from direct assay GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

P56192

(UniProtKB/Swiss-Prot/P) Details

Methionine--tRNA ligase, cytoplasmic

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Aminoacyl-tRNA synthetase multienzyme complex (GO:0017101) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleolus (GO:0005730) 0.8 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.3 Unknown: HDA GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

P62993

(UniProtKB/Swiss-Prot/P) Details

Growth factor receptor-bound protein 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.999 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.999 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleolus (GO:0005730) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Signalosome (GO:0008180) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Endosome (GO:0005768) 0.86 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.971 Unknown: traceable author statement GO PubMed 
Membrane Extrinsic to internal side of plasma membrane (GO:0031234) 0.971 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Grb2-EGFR complex (GO:0070436) 0.971 Experimental: inferred from direct assay GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.999 Unknown: HDA GO PubMed 
Cytosol Vesicle membrane (GO:0012506) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Membrane Cell-cell junction (GO:0005911) 0.971 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

Q9BSJ2

(UniProtKB/Swiss-Prot/P) Details

Gamma-tubulin complex component 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 1 Unknown: traceable author statement GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.96 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Experimental: experimental eSLDB PubMed 
Cytosol Spindle pole (GO:0000922) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Spindle pole body (GO:0005816) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Microtubule organizing center (GO:0005815) 1 Unknown: traceable author statement GO PubMed 
Cytosol Centrosome (GO:0005813) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Centrosome (GO:0005813) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Gamma-tubulin small complex (GO:0008275) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cytoplasmic microtubule (GO:0005881) 1 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.3 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

P05388

(UniProtKB/Swiss-Prot/P) Details

60S acidic ribosomal protein P0

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Organelle PubMed 
Cytosol Ribonucleoprotein complex (GO:0030529) 1 Experimental: experimental Organelle PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Cytosolic large ribosomal subunit (GO:0022625) 1 Unknown: HDA GO PubMed 
Nucleus Nucleus (GO:0005634) 0.8 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.96 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Dendrite (GO:0030425) 0.931 Unknown: inferred from electronic annotation GO PubMed 
Membrane Postsynaptic density (GO:0014069) 0.931 Experimental: inferred from experiment GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.931 Unknown: HDA GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 
Membrane Focal adhesion (GO:0005925) 0.931 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

Q9GZS3

(UniProtKB/Swiss-Prot/P) Details

WD repeat-containing protein 61

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Ski complex (GO:0055087) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Cdc73/Paf1 complex (GO:0016593) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Transcriptionally active chromatin (GO:0035327) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

Q13618

(UniProtKB/Swiss-Prot/P) Details

Cullin-3

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cul3-RING ubiquitin ligase complex (GO:0031463) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytosol (GO:0005829) 1 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 0.937 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.937 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.937 Unknown: traceable author statement GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.86 Experimental: experimental eSLDB PubMed 
Secretory-pathway Golgi membrane (GO:0000139) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Polar microtubule (GO:0005827) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Sperm flagellum (GO:0036126) 0.86 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.86 Unknown: HDA GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

Q00653

(UniProtKB/Swiss-Prot/P) Details

Nuclear factor NF-kappa-B p100 subunit

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Bcl3/NF-kappaB2 complex (GO:0033257) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.998 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.998 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 0.998 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.998 Unknown: traceable author statement GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.998 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

Q15046

(UniProtKB/Swiss-Prot/P) Details

Lysine--tRNA ligase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Aminoacyl-tRNA synthetase multienzyme complex (GO:0017101) 1 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.992 Predicted: SVM decision tree eSLDB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.992 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.992 Experimental: experimental Organelle PubMed 
Mitochondrion Mitochondrial matrix (GO:0005759) 0.992 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 0.8 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.96 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular space (GO:0005615) 0.96 Experimental: inferred from direct assay GO PubMed 
Membrane Membrane (GO:0016020) 0.86 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.86 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

P56537

(UniProtKB/Swiss-Prot/P) Details

Eukaryotic translation initiation factor 6

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.999 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Preribosome, large subunit precursor (GO:0030687) 0.999 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cytosol (GO:0005829) 0.999 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Lamin filament (GO:0005638) 1 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleolus (GO:0005730) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.999 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

O00567

(UniProtKB/Swiss-Prot/P) Details

Nucleolar protein 56

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.997 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Pre-snoRNP complex (GO:0070761) 0.997 Experimental: inferred from direct assay GO PubMed 
Cytosol Small nucleolar ribonucleoprotein complex (GO:0005732) 0.997 Experimental: inferred from direct assay GO PubMed 
Cytosol Box C/D snoRNP complex (GO:0031428) 0.997 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Small-subunit processome (GO:0032040) 0.997 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleolus (GO:0005730) 1 Unknown: traceable author statement GO PubMed 
Nucleus Fibrillar center (GO:0001650) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Fibrillar center (GO:0001650) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.3 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

P47897

(UniProtKB/Swiss-Prot/P) Details

Glutamine--tRNA ligase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Aminoacyl-tRNA synthetase multienzyme complex (GO:0017101) 1 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrial matrix (GO:0005759) 0.3 Unknown: traceable author statement GO PubMed 
Nucleus Macromolecular complex (GO:0032991) 0.8 Experimental: inferred from mutant phenotype GO PubMed 

Interaction Source Database:

HPRD, BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

Q12904

(UniProtKB/Swiss-Prot/P) Details

Aminoacyl tRNA synthase complex-interacting multifunctional protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Cell surface (GO:0009986) 0.972 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Methionyl glutamyl tRNA synthetase complex (GO:0017102) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Aminoacyl-tRNA synthetase multienzyme complex (GO:0017101) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.79 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.79 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.51 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.51 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular space (GO:0005615) 0.94 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Membrane (GO:0016020) 0.972 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 0.972 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed , PubMed 

P54136

Interaction Score
1

P31689

(UniProtKB/Swiss-Prot/P) Details

DnaJ homolog subfamily A member 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Ubiquitin ligase complex (GO:0000151) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 1 Unknown: inferred from electronic annotation GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Microtubule cytoskeleton (GO:0015630) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Microtubule cytoskeleton (GO:0015630) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.86 Experimental: experimental eSLDB PubMed 
Membrane Membrane (GO:0016020) 0.86 Unknown: HDA GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

Q14164

(UniProtKB/Swiss-Prot/P) Details

Inhibitor of nuclear factor kappa-B kinase subunit epsilon

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Unknown: traceable author statement GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Mitochondrion Mitochondrial membrane (GO:0031966) 0.8 Experimental: inferred from mutant phenotype GO PubMed 
Nucleus Nucleus (GO:0005634) 0.972 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.972 Unknown: traceable author statement GO PubMed 
Nucleus PML body (GO:0016605) 0.972 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endosome membrane (GO:0010008) 0.3 Unknown: traceable author statement GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

Q9UQL6

(UniProtKB/Swiss-Prot/P) Details

Histone deacetylase 5

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.998 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.998 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytosol (GO:0005829) 0.998 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.998 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Unknown: traceable author statement GO PubMed 
Nucleus Nuclear speck (GO:0016607) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear speck (GO:0016607) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Histone deacetylase complex (GO:0000118) 1 Unknown: traceable author statement GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.96 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

Q9H0W5

(UniProtKB/Swiss-Prot/P) Details

Coiled-coil domain-containing protein 8

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.998 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.998 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.998 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.996 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.996 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.996 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.996 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Centrosome (GO:0005813) 0.998 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.992 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.992 Experimental: experimental Human Proteinpedia PubMed 
Membrane Plasma membrane (GO:0005886) 0.992 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

P07814

(UniProtKB/Swiss-Prot/P) Details

Bifunctional glutamate/proline--tRNA ligase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
N/A GAIT complex (GO:0097452) 0.8 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Aminoacyl-tRNA synthetase multienzyme complex (GO:0017101) 1 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.79 Unknown: HDA GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.79 Predicted: inferred from sequence or structural similarity GO PubMed 

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

P41091

(UniProtKB/Swiss-Prot/P) Details

Eukaryotic translation initiation factor 2 subunit 3

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Organelle PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Ribonucleoprotein complex (GO:0030529) 1 Experimental: experimental Organelle PubMed 
Cytosol Cytosol (GO:0005829) 1 Unknown: traceable author statement GO PubMed 
Cytosol Eukaryotic translation initiation factor 2 complex (GO:0005850) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.8 Experimental: inferred from direct assay GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

P14868

(UniProtKB/Swiss-Prot/P) Details

Aspartate--tRNA ligase, cytoplasmic

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Unknown: traceable author statement GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Aminoacyl-tRNA synthetase multienzyme complex (GO:0017101) 1 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.51 Unknown: HDA GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 
Membrane Synapse (GO:0045202) 0.51 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

P38398

(UniProtKB/Swiss-Prot/P) Details

Breast cancer type 1 susceptibility protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Ubiquitin ligase complex (GO:0000151) 0.996 Unknown: non-traceable author statement GO PubMed 
Cytosol Ubiquitin ligase complex (GO:0000151) 0.996 Experimental: experimental Organelle PubMed 
Cytosol Cytoplasm (GO:0005737) 0.996 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Unknown: traceable author statement GO PubMed 
Nucleus Macromolecular complex (GO:0032991) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus BRCA1-A complex (GO:0070531) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus BRCA1-BARD1 complex (GO:0031436) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 0.996 Experimental: experimental Organelle PubMed 
Cytosol Gamma-tubulin ring complex (GO:0008274) 0.996 Unknown: non-traceable author statement GO PubMed 
Nucleus Chromosome (GO:0005694) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Nucleus Lateral element (GO:0000800) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.8 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

Q13616

(UniProtKB/Swiss-Prot/P) Details

Cullin-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cullin-RING ubiquitin ligase complex (GO:0031461) 0.999 Experimental: inferred from direct assay GO PubMed 
Cytosol SCF ubiquitin ligase complex (GO:0019005) 0.999 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytosol (GO:0005829) 0.999 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 0.972 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleolus (GO:0005730) 0.972 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.972 Unknown: traceable author statement GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

P41252

(UniProtKB/Swiss-Prot/P) Details

Isoleucine--tRNA ligase, cytoplasmic

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Aminoacyl-tRNA synthetase multienzyme complex (GO:0017101) 1 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.79 Unknown: HDA GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.79 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

P12830

(UniProtKB/Swiss-Prot/P) Details

Cadherin-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.972 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Trans-Golgi network (GO:0005802) 0.972 Experimental: inferred from mutant phenotype GO PubMed 
Secretory-pathway Endosome (GO:0005768) 0.972 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cortical actin cytoskeleton (GO:0030864) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Actin cytoskeleton (GO:0015629) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Lamellipodium (GO:0030027) 1 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Membrane (GO:0016020) 1 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: pTarget method LOCATE PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Internal side of plasma membrane (GO:0009898) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Lateral plasma membrane (GO:0016328) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Catenin complex (GO:0016342) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Flotillin complex (GO:0016600) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Apical junction complex (GO:0043296) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 
Membrane Cell junction (GO:0030054) 1 Unknown: traceable author statement GO PubMed 
Membrane Cell junction (GO:0030054) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Cell-cell adherens junction (GO:0005913) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

P11279

(UniProtKB/Swiss-Prot/P) Details

Lysosome-associated membrane glycoprotein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Neuronal cell body (GO:0043025) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 1 Experimental: inferred from mutant phenotype GO PubMed 
Secretory-pathway Late endosome (GO:0005770) 0.986 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Multivesicular body (GO:0005771) 0.986 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Endosome membrane (GO:0010008) 0.986 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Lysosome (GO:0005764) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Lysosome (GO:0005764) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytolytic granule (GO:0044194) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Lysosomal membrane (GO:0005765) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Secretory-pathway Melanosome (GO:0042470) 0.986 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Alveolar lamellar body (GO:0097208) 0.986 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Integral to synaptic vesicle membrane (GO:0030285) 0.986 Unknown: inferred from electronic annotation GO PubMed 
Membrane Dendrite (GO:0030425) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.999 Unknown: HDA GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.999 Predicted: SVM decision tree eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.999 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.999 Predicted: pTarget method LOCATE PubMed 
Membrane Plasma membrane (GO:0005886) 0.999 Experimental: experimental Organelle PubMed 
Membrane Sarcolemma (GO:0042383) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Membrane External side of plasma membrane (GO:0009897) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.999 Unknown: traceable author statement GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

O00221

(UniProtKB/Swiss-Prot/P) Details

NF-kappa-B inhibitor epsilon

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.994 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.994 Unknown: traceable author statement GO PubMed 
Cytosol Cytosol (GO:0005829) 0.994 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.994 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 0.994 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Fibrillar center (GO:0001650) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Fibrillar center (GO:0001650) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.3 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

P00533

(UniProtKB/Swiss-Prot/P) Details

Epidermal growth factor receptor

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.999 Predicted: SVM decision tree eSLDB PubMed 
Membrane Cell surface (GO:0009986) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Endomembrane system (GO:0012505) 0.972 Experimental: experimental Organelle PubMed 
Cytosol Cytoplasm (GO:0005737) 0.972 Experimental: inferred from direct assay GO PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 0.972 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.994 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.994 Experimental: experimental Organelle PubMed 
Nucleus Nuclear membrane (GO:0031965) 0.994 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Macromolecular complex (GO:0032991) 0.994 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Golgi membrane (GO:0000139) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Endosome (GO:0005768) 0.999 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Early endosome membrane (GO:0031901) 0.999 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endosome membrane (GO:0010008) 0.999 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Clathrin coated vesicle membrane (GO:0030665) 0.999 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.86 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular space (GO:0005615) 0.86 Unknown: non-traceable author statement GO PubMed 
Membrane Membrane (GO:0016020) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Membrane (GO:0016020) 1 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Membrane raft (GO:0045121) 1 Experimental: inferred from direct assay GO PubMed 
Membrane AP-2 adaptor complex (GO:0030122) 1 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: pTarget method LOCATE PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Shc-EGFR complex (GO:0070435) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Receptor complex (GO:0043235) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Apical plasma membrane (GO:0016324) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Basolateral plasma membrane (GO:0016323) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Focal adhesion (GO:0005925) 1 Unknown: HDA GO PubMed 
Membrane Synapse (GO:0045202) 1 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

Q8N163

(UniProtKB/Swiss-Prot/P) Details

Cell cycle and apoptosis regulator protein 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.988 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.988 Experimental: inferred from direct assay GO PubMed 
Cytosol DBIRD complex (GO:0044609) 0.988 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrial matrix (GO:0005759) 0.8 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nuclear body (GO:0016604) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Spliceosomal complex (GO:0005681) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear chromatin (GO:0000790) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

Q14258

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin/ISG15 ligase TRIM25

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.988 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.988 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.988 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nuclear body (GO:0016604) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear body (GO:0016604) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

Q6P1J9

(UniProtKB/Swiss-Prot/P) Details

Parafibromin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.988 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytosol (GO:0005829) 0.988 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.988 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.999 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.999 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.999 Unknown: traceable author statement GO PubMed 
Nucleus Cdc73/Paf1 complex (GO:0016593) 0.999 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear chromosome, telomeric region (GO:0000784) 0.999 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

P41250

(UniProtKB/Swiss-Prot/P) Details

Glycine--tRNA ligase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Unknown: traceable author statement GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.79 Predicted: inferred from biological aspect of ancestor GO PubMed 
Mitochondrion Mitochondrial matrix (GO:0005759) 0.79 Unknown: traceable author statement GO PubMed 
Secretory-pathway Secretory granule (GO:0030141) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Membrane Axon (GO:0030424) 0.96 Experimental: inferred from direct assay GO PubMed 
Membrane Membrane (GO:0016020) 0.96 Experimental: experimental MatrixDB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Predicted: inferred from sequence or structural similarity GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

Q13155

(UniProtKB/Swiss-Prot/P) Details

Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.999 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.999 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Aminoacyl-tRNA synthetase multienzyme complex (GO:0017101) 0.999 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.3 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

Q13509

(UniProtKB/Swiss-Prot/P) Details

Tubulin beta-3 chain

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.3 Unknown: HDA GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Experimental: experimental Organelle PubMed 
Cytosol Microtubule (GO:0005874) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Dendrite (GO:0030425) 0.91 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Axon (GO:0030424) 0.91 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

Q00987

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase Mdm2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.972 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.972 Experimental: inferred from mutant phenotype GO PubMed 
Cytosol Cytosol (GO:0005829) 0.972 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleolus (GO:0005730) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear body (GO:0016604) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Macromolecular complex (GO:0032991) 1 Experimental: inferred from mutant phenotype GO PubMed 
Secretory-pathway Endocytic vesicle membrane (GO:0030666) 0.3 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.51 Unknown: traceable author statement GO PubMed 
Membrane Synapse (GO:0045202) 0.51 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

P49736

(UniProtKB/Swiss-Prot/P) Details

DNA replication licensing factor MCM2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.96 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Human Proteinpedia PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleolus (GO:0005730) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Microtubule cytoskeleton (GO:0015630) 0.96 Experimental: inferred from direct assay GO PubMed 
Nucleus Chromosome (GO:0005694) 1 Experimental: experimental Organelle PubMed 
Nucleus Nuclear chromosome, telomeric region (GO:0000784) 1 Unknown: HDA GO PubMed 
Nucleus MCM complex (GO:0042555) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear origin of replication recognition complex (GO:0005664) 1 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Chromatin (GO:0000785) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

P0CG48

(UniProtKB/Swiss-Prot/P) Details

Polyubiquitin-C

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Myelin sheath (GO:0043209) 0.902 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.969 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.969 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytosol (GO:0005829) 0.969 Unknown: traceable author statement GO PubMed 
Mitochondrion Mitochondrial outer membrane (GO:0005741) 0.3 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 0.956 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.956 Unknown: HDA GO PubMed 
Nucleus Nucleus (GO:0005634) 0.956 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.956 Unknown: traceable author statement GO PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 0.657 Unknown: traceable author statement GO PubMed 
Secretory-pathway Endosome membrane (GO:0010008) 0.657 Unknown: traceable author statement GO PubMed 
Secretory-pathway Endocytic vesicle membrane (GO:0030666) 0.657 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.902 Experimental: experimental MatrixDB PubMed 
Extracellular Host cell (GO:0043657) 0.902 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular space (GO:0005615) 0.902 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 0.902 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.902 Unknown: traceable author statement GO PubMed 
Cytosol Vesicle (GO:0031982) 0.969 Unknown: HDA GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.969 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

Q15287

(UniProtKB/Swiss-Prot/P) Details

RNA-binding protein with serine-rich domain 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
N/A ASAP complex (GO:0061574) 0.8 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.958 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.958 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.958 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nuclear speck (GO:0016607) 1 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Exon-exon junction complex (GO:0035145) 1 Unknown: traceable author statement GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

O43681

(UniProtKB/Swiss-Prot/P) Details

ATPase ASNA1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.956 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.956 Unknown: traceable author statement GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.956 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleolus (GO:0005730) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleolus (GO:0005730) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 0.3 Unknown: traceable author statement GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.956 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

P16435

(UniProtKB/Swiss-Prot/P) Details

NADPH--cytochrome P450 reductase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.992 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.992 Experimental: inferred from direct assay GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.992 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.987 Predicted: pTarget method LOCATE PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.987 Experimental: experimental Organelle PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.987 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 0.987 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.853 Unknown: HDA GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.853 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.853 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

P13569

(UniProtKB/Swiss-Prot/P) Details

Cystic fibrosis transmembrane conductance regulator

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Cell surface (GO:0009986) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.972 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.972 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Predicted: inferred from sequence or structural similarity GO PubMed 
Nucleus Macromolecular complex (GO:0032991) 0.94 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Endoplasmic reticulum Sec complex (GO:0031205) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi-associated vesicle membrane (GO:0030660) 1 Unknown: traceable author statement GO PubMed 
Secretory-pathway Recycling endosome (GO:0055037) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Recycling endosome membrane (GO:0055038) 1 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Early endosome (GO:0005769) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Early endosome membrane (GO:0031901) 1 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Endosome membrane (GO:0010008) 1 Unknown: traceable author statement GO PubMed 
Cytosol Lysosomal membrane (GO:0005765) 0.972 Unknown: traceable author statement GO PubMed 
Secretory-pathway Clathrin coated vesicle membrane (GO:0030665) 1 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Chloride channel complex (GO:0034707) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to plasma membrane (GO:0005887) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Apical plasma membrane (GO:0016324) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
1

Q99496

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase RING2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Ubiquitin ligase complex (GO:0000151) 0.94 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.94 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nuclear body (GO:0016604) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear body (GO:0016604) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus MLL1 complex (GO:0071339) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus PcG protein complex (GO:0031519) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus PRC1 complex (GO:0035102) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Euchromatin (GO:0000791) 1 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Sex chromatin (GO:0001739) 1 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.999

P09622

(UniProtKB/Swiss-Prot/P) Details

Dihydrolipoyl dehydrogenase, mitochondrial

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Myelin sheath (GO:0043209) 0.51 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Pyruvate dehydrogenase complex (GO:0045254) 0.96 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.999 Predicted: SVM decision tree eSLDB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.999 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.999 Experimental: experimental Organelle PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.999 Predicted: PAML algorithm PA-GOSUB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Mitochondrion Mitochondrial matrix (GO:0005759) 0.999 Unknown: traceable author statement GO PubMed 
Cytosol Oxoglutarate dehydrogenase complex (GO:0045252) 0.96 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Experimental: experimental Human Proteinpedia PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.992 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Acrosomal matrix (GO:0043159) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Membrane Motile cilium (GO:0031514) 0.51 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.999

Q92844

(UniProtKB/Swiss-Prot/P) Details

TRAF family member-associated NF-kappa-B activator

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.988 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.988 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.988 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleolus (GO:0005730) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Macromolecular complex (GO:0032991) 0.96 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.999

O95568

(UniProtKB/Swiss-Prot/P) Details

Histidine protein methyltransferase 1 homolog

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.982 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.982 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.982 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Macromolecular complex (GO:0032991) 0.96 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.999

Q13951

(UniProtKB/Swiss-Prot/P) Details

Core-binding factor subunit beta

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.994 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.994 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.994 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.994 Unknown: traceable author statement GO PubMed 
Nucleus Core-binding factor complex (GO:0016513) 0.994 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.3 Unknown: HDA GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.999

O43776

(UniProtKB/Swiss-Prot/P) Details

Asparagine--tRNA ligase, cytoplasmic

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.999 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Unknown: traceable author statement GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.999 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.999 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.999

Q16526

(UniProtKB/Swiss-Prot/P) Details

Cryptochrome-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.94 Predicted: SVM decision tree eSLDB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.86 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 0.988 Predicted: inferred from sequence or structural similarity GO PubMed 
Nucleus Nucleus (GO:0005634) 0.988 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nuclear membrane (GO:0031965) 0.988 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Microtubule cytoskeleton (GO:0015630) 0.94 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.998

A2RTX5

(UniProtKB/Swiss-Prot/P) Details

Probable threonine--tRNA ligase 2, cytoplasmic

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
N/A Cellular component (GO:0005575) 0.3 Unknown: no biological data available GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.998 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.998 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.998 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytoplasm (GO:0005737) 0.998 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.998 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.998

Q8NDD1

(UniProtKB/Swiss-Prot/P) Details

Uncharacterized protein C1orf131

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.999 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.999 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleolus (GO:0005730) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Chromosome (GO:0005694) 0.999 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.998

Q92734

(UniProtKB/Swiss-Prot/P) Details

Protein TFG

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.98 Unknown: non-traceable author statement GO PubMed 
Cytosol Cytosol (GO:0005829) 0.98 Unknown: traceable author statement GO PubMed 
Cytosol Cytosol (GO:0005829) 0.98 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.98 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.91 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Endoplasmic reticulum exit site (GO:0070971) 0.86 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi membrane (GO:0000139) 0.86 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.997

Q9NRD1

(UniProtKB/Swiss-Prot/P) Details

F-box only protein 6

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol SCF ubiquitin ligase complex (GO:0019005) 0.997 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.997 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.997 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.997 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.997 Unknown: traceable author statement GO PubMed 
Secretory-pathway Endoplasmic reticulum quality control compartment (GO:0044322) 0.3 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.996

G8JLD5

(UniProtKB/TrEmbl/P) Details

Dynamin-1-like protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.988 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytosol (GO:0005829) 0.988 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.988 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.996

P19320

(UniProtKB/Swiss-Prot/P) Details

Vascular cell adhesion protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.998 Predicted: SVM decision tree eSLDB PubMed 
Membrane Cell surface (GO:0009986) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Apical part of cell (GO:0045177) 0.972 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.998 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.998 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Early endosome (GO:0005769) 0.998 Experimental: inferred from direct assay GO PubMed 
Cytosol Podosome (GO:0002102) 0.972 Experimental: inferred from direct assay GO PubMed 
Membrane Microvillus (GO:0005902) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Filopodium (GO:0030175) 1 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.988 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.988 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.988 Experimental: inferred from direct assay GO PubMed 
Membrane Membrane (GO:0016020) 1 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Sarcolemma (GO:0042383) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane External side of plasma membrane (GO:0009897) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex (GO:0071065) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.972 Unknown: HDA GO PubMed 
Membrane Cell junction (GO:0030054) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed , PubMed 

P54136

Interaction Score
0.996

Q9Y216

(UniProtKB/Swiss-Prot/P) Details

Myotubularin-related protein 7

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.958 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.958 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.958 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.3 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.994

Q68D86

(UniProtKB/Swiss-Prot/P) Details

Coiled-coil domain-containing protein 102B

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.982 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.982 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.982 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: pTarget method LOCATE PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.994

P05412

(UniProtKB/Swiss-Prot/P) Details

Transcription factor AP-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Transcriptional repressor complex (GO:0017053) 1 Unknown: inferred from electronic annotation GO PubMed 
Nucleus AP1 complex (GO:0035976) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Chromosome (GO:0005694) 1 Experimental: experimental Organelle PubMed 
Nucleus Nuclear chromosome (GO:0000228) 1 Unknown: traceable author statement GO PubMed 
Nucleus Nuclear euchromatin (GO:0005719) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.994

Q96K83

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein 521

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.988 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.988 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.988 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.994

P19367

(UniProtKB/Swiss-Prot/P) Details

Hexokinase-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.982 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.982 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytosol (GO:0005829) 0.982 Predicted: inferred from biological aspect of ancestor GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.972 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.972 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Mitochondrion Mitochondrial outer membrane (GO:0005741) 0.972 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.992

P04629

(UniProtKB/Swiss-Prot/P) Details

High affinity nerve growth factor receptor

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Cell surface (GO:0009986) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Neuronal cell body (GO:0043025) 0.897 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytosol (GO:0005829) 0.897 Unknown: unspecified method The Human Protein Atlas PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.897 Unknown: unspecified method The Human Protein Atlas PubMed 
Nucleus Macromolecular complex (GO:0032991) 0.7 Predicted: inferred from sequence or structural similarity GO PubMed 
Secretory-pathway Endosome (GO:0005768) 0.994 Experimental: experimental eSLDB PubMed 
Secretory-pathway Endosome (GO:0005768) 0.994 Unknown: traceable author statement GO PubMed 
Secretory-pathway Early endosome (GO:0005769) 0.994 Predicted: inferred from sequence or structural similarity GO PubMed 
Secretory-pathway Late endosome membrane (GO:0031902) 0.994 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Early endosome membrane (GO:0031901) 0.994 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Late endosome (GO:0005770) 0.994 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Lysosome (GO:0005764) 0.897 Predicted: pTarget method LOCATE PubMed 
Membrane Dendrite (GO:0030425) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Axon (GO:0030424) 1 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Predicted: SVM decision tree eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to plasma membrane (GO:0005887) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Receptor complex (GO:0043235) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.992

P01106

(UniProtKB/Swiss-Prot/P) Details

Myc proto-oncogene protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleolus (GO:0005730) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Macromolecular complex (GO:0032991) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear chromatin (GO:0000790) 1 Experimental: inferred from mutant phenotype GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.992

P28329

(UniProtKB/Swiss-Prot/P) Details

Choline O-acetyltransferase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.51 Unknown: traceable author statement GO PubMed 
Cytosol Cytosol (GO:0005829) 0.51 Unknown: traceable author statement GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Experimental: experimental Human Proteinpedia PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Experimental: experimental Organelle PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.99

B4DHN5

(UniProtKB/TrEmbl/P) Details

cDNA FLJ55055, moderately similar to Syntenin-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nuclear membrane (GO:0031965) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.99

G5EA09

(UniProtKB/TrEmbl/P) Details

Syndecan binding protein (Syntenin), isoform CRA_a

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nuclear membrane (GO:0031965) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.985

Q86VU5

(UniProtKB/Swiss-Prot/P) Details

Catechol O-methyltransferase domain-containing protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.94 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.972 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.972 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.972 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.985

Q96BZ8

(UniProtKB/Swiss-Prot/P) Details

Leukocyte receptor cluster member 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
N/A Cellular component (GO:0005575) 0.3 Unknown: no biological data available GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Plasma membrane (GO:0005886) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.984

P34810

(UniProtKB/Swiss-Prot/P) Details

Macrosialin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.94 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.86 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endosome membrane (GO:0010008) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Lysosome (GO:0005764) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.897 Unknown: traceable author statement GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.897 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.897 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.897 Unknown: traceable author statement GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.98

G3XA89

(UniProtKB/TrEmbl/P) Details

E3 ubiquitin-protein ligase Mdm2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.975

Q92692

(UniProtKB/Swiss-Prot/P) Details

Nectin-2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Cell surface (GO:0009986) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Fibrillar center (GO:0001650) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Integral to plasma membrane (GO:0005887) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.3 Unknown: HDA GO PubMed 
Membrane Cell junction (GO:0030054) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Focal adhesion (GO:0005925) 1 Unknown: HDA GO PubMed 
Membrane Cell-cell junction (GO:0005911) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Cell-cell adherens junction (GO:0005913) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Zonula adherens (GO:0005915) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Cell-cell contact zone (GO:0044291) 1 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.973

P08559

(UniProtKB/Swiss-Prot/P) Details

Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Myelin sheath (GO:0043209) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Pyruvate dehydrogenase complex (GO:0045254) 0.8 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 1 Experimental: experimental eSLDB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 1 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 1 Predicted: pTarget method LOCATE PubMed 
Mitochondrion Mitochondrion (GO:0005739) 1 Experimental: experimental Organelle PubMed 
Mitochondrion Mitochondrion (GO:0005739) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Mitochondrion Mitochondrial matrix (GO:0005759) 1 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 0.86 Unknown: HDA GO PubMed 
Nucleus Nucleolus (GO:0005730) 0.86 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.971

Q9NPY3

(UniProtKB/Swiss-Prot/P) Details

Complement component C1q receptor

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Cell surface (GO:0009986) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.902 Experimental: experimental Human Proteinpedia PubMed 
Secretory-pathway Secretory granule membrane (GO:0030667) 0.902 Unknown: traceable author statement GO PubMed 
Secretory-pathway Tertiary granule membrane (GO:0070821) 0.902 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.988 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.988 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular matrix (GO:0031012) 0.988 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.999 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.999 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.999 Experimental: experimental Human Proteinpedia PubMed 
Membrane Plasma membrane (GO:0005886) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.959

H0YL19

(UniProtKB/TrEmbl/P) Details

WD repeat-containing protein 61

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.94

Q5ST81

(UniProtKB/TrEmbl/P) Details

Tubulin beta chain

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.94 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Microtubule cytoskeleton (GO:0015630) 0.94 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.939

Q6PJX3

(UniProtKB/TrEmbl/P) Details

STAU1 protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.8 Experimental: experimental Human Proteinpedia PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.91

Q2VIR3

(UniProtKB/Swiss-Prot/P) Details

Eukaryotic translation initiation factor 2 subunit 3B

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.855

P19438

(UniProtKB/Swiss-Prot/P) Details

Tumor necrosis factor receptor superfamily member 1A

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.96 Experimental: experimental eSLDB PubMed 
Membrane Cell surface (GO:0009986) 1 Unknown: inferred from electronic annotation GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: inferred from biological aspect of ancestor GO PubMed 
Secretory-pathway Golgi membrane (GO:0000139) 0.96 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.992 Unknown: non-traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.992 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.992 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.992 Experimental: inferred from direct assay GO PubMed 
Membrane Membrane (GO:0016020) 1 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Experimental: experimental eSLDB PubMed 
Membrane Membrane raft (GO:0045121) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Integral to plasma membrane (GO:0005887) 1 Unknown: traceable author statement GO PubMed 
Membrane Receptor complex (GO:0043235) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.823

Q01726

(UniProtKB/Swiss-Prot/P) Details

Melanocyte-stimulating hormone receptor

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Intracellular (GO:0005622) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.997 Predicted: SVM decision tree eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.997 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.997 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 0.997 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.997 Unknown: traceable author statement GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.812

P30480

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, B-42 alpha chain

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.94 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to membrane (GO:0016021) 0.8 Experimental: experimental eSLDB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.8

A8MU58

(UniProtKB/TrEmbl/P) Details

Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.8

F8W950

(UniProtKB/TrEmbl/P) Details

Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.8

Q53EQ3

(UniProtKB/TrEmbl/P) Details

Gamma-tubulin complex component

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoskeleton (GO:0005856) 0.8 Experimental: experimental eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.794

H3BMS0

(UniProtKB/TrEmbl/P) Details

RNA-binding protein with serine-rich domain 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.794

A0A087WVR4

(UniProtKB/TrEmbl/P) Details

Myc proto-oncogene protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.794

A7UKX8

(UniProtKB/TrEmbl/P) Details

E3 ubiquitin-protein ligase Mdm2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.79

Q8NHW5

(UniProtKB/Swiss-Prot/P) Details

60S acidic ribosomal protein P0-like

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.79 Predicted: pTarget method LOCATE PubMed 
Cytosol Ribosome (GO:0005840) 0.79 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.763

Q7L4K8

(UniProtKB/TrEmbl/P) Details

IARS protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.743

P35610

(UniProtKB/Swiss-Prot/P) Details

Sterol O-acyltransferase 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Mitochondrion Mitochondrion (GO:0005739) 0.8 Experimental: experimental Organelle PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 1 Experimental: experimental Organelle PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 1 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.958 Experimental: inferred from direct assay GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.958 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.958 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.726

E9PFD7

(UniProtKB/TrEmbl/P) Details

Receptor protein-tyrosine kinase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.726

Q504U8

(UniProtKB/TrEmbl/P) Details

Receptor protein-tyrosine kinase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.7

Q6P0M4

(UniProtKB/TrEmbl/P) Details

IARS protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.7

P78542

(UniProtKB/TrEmbl/P) Details

Hexokinase 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.7

Q59FD4

(UniProtKB/TrEmbl/P) Details

Hexokinase 1 isoform HKI variant

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.7

Q53G92

(UniProtKB/TrEmbl/P) Details

Tubulin beta chain

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.7

Q5SU16

(UniProtKB/TrEmbl/P) Details

Tubulin beta chain

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.7

A2I2P0

(UniProtKB/TrEmbl/P) Details

Cryptochrome 1 (Photolyase-like), isoform CRA_a

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.694

Q96DS0

(UniProtKB/TrEmbl/P) Details

MDM2 variant FB55

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.694

Q6LEN5

(UniProtKB/TrEmbl/P) Details

Choline acetyltransferase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.694

Q6LEN6

(UniProtKB/TrEmbl/P) Details

Choline acetyltransferase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.652

Q9UII7

(UniProtKB/TrEmbl/P) Details

E-cadherin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to membrane (GO:0016021) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.64

B7Z2I3

(UniProtKB/TrEmbl/P) Details

Receptor protein-tyrosine kinase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.64

E7BSV0

(UniProtKB/TrEmbl/P) Details

Receptor protein-tyrosine kinase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.64

F2YGG7

(UniProtKB/TrEmbl/P) Details

Receptor protein-tyrosine kinase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.64

X5DR71

(UniProtKB/TrEmbl/P) Details

Tyrosine-protein kinase receptor

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0.64

A0A024R730

(UniProtKB/TrEmbl/P) Details

Cystic fibrosis transmembrane conductance regulator

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0

Q59F99

(UniProtKB/TrEmbl/P) Details

Staufen isoform b variant

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.8 Experimental: experimental eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P54136

Interaction Score
0

E9PEX6

(UniProtKB/TrEmbl/P) Details

Dihydrolipoyl dehydrogenase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Mitochondrion Mitochondrion (GO:0005739) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

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ComPPI is published in Nucleic Acids Research Database Issue 2015