Q07108

Early activation antigen CD69 // UniProt Profile

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Species	H. sapiens
Number of Interactions	24 / 25
Average Interaction Score	0.823

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Macromolecular complex (GO:0032991)	0.8	Experimental: inferred from mutant phenotype	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.98	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.98	Experimental: experimental	Organelle	PubMed
Membrane	External side of plasma membrane (GO:0009897)	0.98	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	0.98	Unknown: traceable author statement	GO	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

Q07108

Interaction Score

0.997

P21453

(UniProtKB/Swiss-Prot/P) Details

Sphingosine 1-phosphate receptor 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Membrane raft (GO:0045121)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	External side of plasma membrane (GO:0009897)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Intrinsic to plasma membrane (GO:0031226)	0.999	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

IntAct, DIP

Interaction Source Publication:

PubMed

Q07108

Interaction Score

0.997

Q8NFZ8

(UniProtKB/Swiss-Prot/P) Details

Cell adhesion molecule 4

Q07108

Interaction Score

0.993

O95832

(UniProtKB/Swiss-Prot/P) Details

Claudin-1

Q07108

Interaction Score

0.992

Q15125

(UniProtKB/Swiss-Prot/P) Details

3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nuclear envelope (GO:0005635)	0.8	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.999	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.999	Unknown: traceable author statement	GO	PubMed
Cytosol	Peroxisome (GO:0005777)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.958	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.958	Experimental: experimental	Organelle	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	0.958	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q07108

Interaction Score

0.992

P21145

(UniProtKB/Swiss-Prot/P) Details

Myelin and lymphocyte protein

Q07108

Interaction Score

0.992

Q01453

(UniProtKB/Swiss-Prot/P) Details

Peripheral myelin protein 22

Q07108

Interaction Score

0.987

A6NDB9

(UniProtKB/Swiss-Prot/P) Details

Paralemmin-3

Q07108

Interaction Score

0.983

Q8TB61

(UniProtKB/Swiss-Prot/P) Details

Adenosine 3'-phospho 5'-phosphosulfate transporter 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Integral to endoplasmic reticulum membrane (GO:0030176)	0.999	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.999	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.999	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.999	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Integral to Golgi membrane (GO:0030173)	0.999	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.972	Experimental: inferred from direct assay	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.972	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.972	Unknown: non-traceable author statement	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q07108

Interaction Score

0.983

P27449

(UniProtKB/Swiss-Prot/P) Details

V-type proton ATPase 16 kDa proteolipid subunit

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endosome membrane (GO:0010008)	0.657	Unknown: traceable author statement	GO	PubMed
Cytosol	Vacuole (GO:0005773)	0.971	Experimental: experimental	eSLDB	PubMed
Cytosol	Vacuolar proton-transporting V-type ATPase, V0 domain (GO:0000220)	0.971	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Lysosomal membrane (GO:0005765)	0.971	Unknown: HDA	GO	PubMed
Secretory-pathway	Phagocytic vesicle membrane (GO:0030670)	0.657	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Tertiary granule membrane (GO:0070821)	0.657	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.971	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.971	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.971	Unknown: traceable author statement	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.971	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.971	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q07108

Interaction Score

0.978

Q9NZG7

(UniProtKB/Swiss-Prot/P) Details

Ninjurin-2

Q07108

Interaction Score

0.978

P47884

(UniProtKB/Swiss-Prot/P) Details

Olfactory receptor 1D4

Q07108

Interaction Score

0.971

Q9NS64

(UniProtKB/Swiss-Prot/P) Details

Protein reprimo

Q07108

Interaction Score

0.971

O75841

(UniProtKB/Swiss-Prot/P) Details

Uroplakin-1b

Q07108

Interaction Score

0.957

P09471

(UniProtKB/Swiss-Prot/P) Details

Guanine nucleotide-binding protein G(o) subunit alpha

Q07108

Interaction Score

0.951

P11216

(UniProtKB/Swiss-Prot/P) Details

Glycogen phosphorylase, brain form

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Azurophil granule lumen (GO:0035578)	0.3	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.86	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.86	Experimental: experimental	MatrixDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.999	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q07108

Interaction Score

0.919

Q5TGU0

(UniProtKB/Swiss-Prot/P) Details

Translocator protein 2

Q07108

Interaction Score

0.807

Q8WZ59

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 190

Q07108

Interaction Score

0.8

Q12824

(UniProtKB/Swiss-Prot/P) Details

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.8	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Fibrillar center (GO:0001650)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Fibrillar center (GO:0001650)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Unknown: HDA	GO	PubMed
Nucleus	SWI/SNF complex (GO:0016514)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	NBAF complex (GO:0071565)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	NpBAF complex (GO:0071564)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Chromosome (GO:0005694)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nuclear chromatin (GO:0000790)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q07108

Interaction Score

0.79

G5E975

(UniProtKB/TrEmbl/P) Details

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1, isoform CRA_c

Q07108

Interaction Score

0.778

Q9H836

(UniProtKB/TrEmbl/P) Details

cDNA FLJ13963 fis, clone Y79AA1001299, highly similar to Homo sapiens integrase interactor 1b protein

Q07108

Interaction Score

0.64

Q6P6B1

(UniProtKB/Swiss-Prot/P) Details

Glutamate-rich protein 5

Q07108

Interaction Score

0.294

A0A1B0GTW0

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

Q07108

Interaction Score

Q8N6I9

(UniProtKB/TrEmbl/P) Details

GNAO1 protein

Q07108

Interaction Score

Q6AWC5

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein DKFZp686O0962

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Q07108

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

Q07108

P21453

Sphingosine 1-phosphate receptor 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q07108

Q8NFZ8

Cell adhesion molecule 4

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q07108

O95832

Claudin-1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q07108

Q15125

3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q07108

P21145

Myelin and lymphocyte protein

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q07108

Q01453

Peripheral myelin protein 22

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q07108

A6NDB9

Paralemmin-3

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q07108

Q8TB61

Adenosine 3'-phospho 5'-phosphosulfate transporter 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q07108

P27449

V-type proton ATPase 16 kDa proteolipid subunit

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q07108

Q9NZG7

Ninjurin-2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q07108

P47884

Olfactory receptor 1D4

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q07108

Q9NS64

Protein reprimo

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q07108