Q13889

General transcription factor IIH subunit 3 // UniProt Profile

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Species	H. sapiens
Number of Interactions	20 / 33
Average Interaction Score	0.835

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
N/A	Transcriptional preinitiation complex (GO:0097550)	0.8	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Transcription factor TFIID complex (GO:0005669)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Holo TFIIH complex (GO:0005675)	1	Experimental: inferred from direct assay	GO	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

Q13889

Interaction Score

P15927

(UniProtKB/Swiss-Prot/P) Details

Replication protein A 32 kDa subunit

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	PML body (GO:0016605)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Chromosome (GO:0005694)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Site of double-strand break (GO:0035861)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear chromosome, telomeric region (GO:0000784)	1	Unknown: HDA	GO	PubMed
Nucleus	DNA replication factor A complex (GO:0005662)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Chromatin (GO:0000785)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Chromosome, telomeric region (GO:0000781)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q13889

Interaction Score

Q12888

(UniProtKB/Swiss-Prot/P) Details

TP53-binding protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.96	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Site of double-strand break (GO:0035861)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear chromosome, telomeric region (GO:0000784)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Replication fork (GO:0005657)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Condensed chromosome kinetochore (GO:0000777)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Chromosome, telomeric region (GO:0000781)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13889

Interaction Score

P27694

(UniProtKB/Swiss-Prot/P) Details

Replication protein A 70 kDa DNA-binding subunit

Q13889

Interaction Score

P18074

(UniProtKB/Swiss-Prot/P) Details

General transcription and DNA repair factor IIH helicase subunit XPD

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Transcription factor TFIID complex (GO:0005669)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Holo TFIIH complex (GO:0005675)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Cyclin-dependent protein kinase activating kinase holoenzyme complex (GO:0019907)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Core TFIIH complex (GO:0000439)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Spindle (GO:0005819)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	MMXD complex (GO:0071817)	0.998	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

IntAct, DIP, BioGRID

Interaction Source Publication:

PubMed

, PubMed

Q13889

Interaction Score

Q92759

(UniProtKB/Swiss-Prot/P) Details

General transcription factor IIH subunit 4

Q13889

Interaction Score

Q13888

(UniProtKB/Swiss-Prot/P) Details

General transcription factor IIH subunit 2

Q13889

Interaction Score

P10275

(UniProtKB/Swiss-Prot/P) Details

Androgen receptor

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.86	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.86	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear chromatin (GO:0000790)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.3	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q13889

Interaction Score

P32780

(UniProtKB/Swiss-Prot/P) Details

General transcription factor IIH subunit 1

Q13889

Interaction Score

P51946

(UniProtKB/Swiss-Prot/P) Details

Cyclin-H

Q13889

Interaction Score

P50613

(UniProtKB/Swiss-Prot/P) Details

Cyclin-dependent kinase 7

Q13889

Interaction Score

P19447

(UniProtKB/Swiss-Prot/P) Details

General transcription and DNA repair factor IIH helicase subunit XPB

Q13889

Interaction Score

P35244

(UniProtKB/Swiss-Prot/P) Details

Replication protein A 14 kDa subunit

Q13889

Interaction Score

P51948

(UniProtKB/Swiss-Prot/P) Details

CDK-activating kinase assembly factor MAT1

Q13889

Interaction Score

0.999

Q6P1K8

(UniProtKB/Swiss-Prot/P) Details

General transcription factor IIH subunit 2-like protein

Q13889

Interaction Score

0.986

Q6ZYL4

(UniProtKB/Swiss-Prot/P) Details

General transcription factor IIH subunit 5

Q13889

Interaction Score

0.91

Q9NUA2

(UniProtKB/TrEmbl/P) Details

Androgen receptor

Q13889

Interaction Score

0.8

A4D105

(UniProtKB/TrEmbl/P) Details

Replication protein A3, 14kDa, isoform CRA_b

Q13889

Interaction Score

Q86XA9

(UniProtKB/Swiss-Prot/P) Details

HEAT repeat-containing protein 5A

Q13889

Interaction Score

Q08830

(UniProtKB/Swiss-Prot/P) Details

Fibrinogen-like protein 1

Q13889

Interaction Score

A0A087WUX9

(UniProtKB/TrEmbl/P) Details

Androgen receptor

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Q13889

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

Q13889

P15927

Replication protein A 32 kDa subunit

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q13889

Q12888

TP53-binding protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q13889

P27694

Replication protein A 70 kDa DNA-binding subunit

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q13889

P18074

General transcription and DNA repair factor IIH helicase subunit XPD

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q13889

Q92759

General transcription factor IIH subunit 4

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q13889

Q13888

General transcription factor IIH subunit 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q13889

P10275

Androgen receptor

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q13889

P32780

General transcription factor IIH subunit 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q13889

P51946

Cyclin-H

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q13889

P50613

Cyclin-dependent kinase 7

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q13889

P19447

General transcription and DNA repair factor IIH helicase subunit XPB

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q13889

P35244

Replication protein A 14 kDa subunit

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q13889