Q14156

Protein EFR3 homolog A // UniProt Profile

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Species	H. sapiens
Number of Interactions	40 / 50
Average Interaction Score	0.817

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

Q14156

Interaction Score

P23469

(UniProtKB/Swiss-Prot/P) Details

Receptor-type tyrosine-protein phosphatase epsilon

Q14156

Interaction Score

Q99677

(UniProtKB/Swiss-Prot/P) Details

Lysophosphatidic acid receptor 4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear body (GO:0016604)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear body (GO:0016604)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q14156

Interaction Score

P12830

(UniProtKB/Swiss-Prot/P) Details

Cadherin-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.972	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Trans-Golgi network (GO:0005802)	0.972	Experimental: inferred from mutant phenotype	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cortical actin cytoskeleton (GO:0030864)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Lamellipodium (GO:0030027)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.958	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.958	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.958	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: pTarget method	LOCATE	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Internal side of plasma membrane (GO:0009898)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Lateral plasma membrane (GO:0016328)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Catenin complex (GO:0016342)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Flotillin complex (GO:0016600)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Apical junction complex (GO:0043296)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Cell-cell adherens junction (GO:0005913)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q14156

Interaction Score

O75351

(UniProtKB/Swiss-Prot/P) Details

Vacuolar protein sorting-associated protein 4B

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Flemming body (GO:0090543)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.972	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Late endosome membrane (GO:0031902)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endosome membrane (GO:0010008)	0.972	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Vacuole (GO:0005773)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Intermediate filament cytoskeleton (GO:0045111)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Spindle pole (GO:0000922)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.96	Experimental: experimental	eSLDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q14156

Interaction Score

0.997

Q15717

(UniProtKB/Swiss-Prot/P) Details

ELAV-like protein 1

Q14156

Interaction Score

0.996

Q16288

(UniProtKB/Swiss-Prot/P) Details

NT-3 growth factor receptor

Q14156

Interaction Score

0.996

O76081

(UniProtKB/Swiss-Prot/P) Details

Regulator of G-protein signaling 20

Q14156

Interaction Score

0.996

P18827

(UniProtKB/Swiss-Prot/P) Details

Syndecan-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi lumen (GO:0005796)	0.3	Unknown: traceable author statement	GO	PubMed
Cytosol	Lysosomal lumen (GO:0043202)	0.51	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: pTarget method	LOCATE	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	External side of plasma membrane (GO:0009897)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.51	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q14156

Interaction Score

0.995

Q92845

(UniProtKB/Swiss-Prot/P) Details

Kinesin-associated protein 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.902	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Spindle microtubule (GO:0005876)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Kinesin II complex (GO:0016939)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cilium basal body (GO:0036064)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Condensed nuclear chromosome (GO:0000794)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Periciliary membrane compartment (GO:1990075)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Axoneme (GO:0005930)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Cilium (GO:0005929)	0.657	Unknown: traceable author statement	GO	PubMed
Membrane	Photoreceptor connecting cilium (GO:0032391)	0.657	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

Q14156

Interaction Score

0.994

Q9UPP5

(UniProtKB/Swiss-Prot/P) Details

AP2-interacting clathrin-endocytosis protein

Q14156

Interaction Score

0.993

Q8TD20

(UniProtKB/Swiss-Prot/P) Details

Solute carrier family 2, facilitated glucose transporter member 12

Q14156

Interaction Score

0.991

Q9NT62

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin-like-conjugating enzyme ATG3

Q14156

Interaction Score

0.99

P28335

(UniProtKB/Swiss-Prot/P) Details

5-hydroxytryptamine receptor 2C

Q14156

Interaction Score

0.987

P08173

(UniProtKB/Swiss-Prot/P) Details

Muscarinic acetylcholine receptor M4

Q14156

Interaction Score

0.987

Q5XUX0

(UniProtKB/Swiss-Prot/P) Details

F-box only protein 31

Q14156

Interaction Score

0.985

Q15714

(UniProtKB/Swiss-Prot/P) Details

TSC22 domain family protein 1

Q14156

Interaction Score

0.971

Q8NFB2

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 185A

Q14156

Interaction Score

0.971

Q99496

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase RING2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Ubiquitin ligase complex (GO:0000151)	0.94	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	MLL1 complex (GO:0071339)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	PcG protein complex (GO:0031519)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	PRC1 complex (GO:0035102)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Euchromatin (GO:0000791)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Sex chromatin (GO:0001739)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q14156

Interaction Score

0.97

Q6PEY0

(UniProtKB/Swiss-Prot/P) Details

Gap junction beta-7 protein

Q14156

Interaction Score

0.946

Q96P81

(UniProtKB/TrEmbl/P) Details

PTPRE

Q14156

Interaction Score

0.946

Q9NRE1

(UniProtKB/Swiss-Prot/P) Details

Matrix metalloproteinase-26

Q14156

Interaction Score

0.93

Q96AZ6

(UniProtKB/Swiss-Prot/P) Details

Interferon-stimulated gene 20 kDa protein

Q14156

Interaction Score

0.93

P09067

(UniProtKB/Swiss-Prot/P) Details

Homeobox protein Hox-B5

Q14156

Interaction Score

0.898

A0A0C4DGU8

(UniProtKB/TrEmbl/P) Details

F-box only protein 31

Q14156

Interaction Score

0.882

B7Z7U4

(UniProtKB/TrEmbl/P) Details

Tyrosine-protein kinase receptor

Q14156

Interaction Score

0.856

Q9UII7

(UniProtKB/TrEmbl/P) Details

E-cadherin

Q14156

Interaction Score

0.768

Q8TCB3

(UniProtKB/TrEmbl/P) Details

TMEM185A protein

Q14156

Interaction Score

0.7

O00472

(UniProtKB/Swiss-Prot/P) Details

RNA polymerase II elongation factor ELL2

Q14156

Interaction Score

0.691

Q6ZMY9

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein 517

Q14156

Interaction Score

0.687

Q53EQ6

(UniProtKB/Swiss-Prot/P) Details

Tigger transposable element-derived protein 5

Q14156

Interaction Score

0.672

Q96CY4

(UniProtKB/TrEmbl/P) Details

Neurotrophic tyrosine kinase, receptor, type 3, isoform CRA_e

Q14156

Interaction Score

0.64

X5DNW6

(UniProtKB/TrEmbl/P) Details

Tyrosine-protein kinase receptor

Q14156

Interaction Score

0.64

X5D7M5

(UniProtKB/TrEmbl/P) Details

Tyrosine-protein kinase receptor

Q14156

Interaction Score

0.64

X5D2R1

(UniProtKB/TrEmbl/P) Details

Tyrosine-protein kinase receptor

Q14156

Interaction Score

0.56

A0A1B0GWG1

(UniProtKB/TrEmbl/P) Details

BTB/POZ domain-containing protein 8

Q14156

Interaction Score

0.49

A0AV05

(UniProtKB/TrEmbl/P) Details

Zinc finger protein 517

Q14156

Interaction Score

0.49

Q59FW6

(UniProtKB/TrEmbl/P) Details

Elongation factor, RNA polymerase II, 2 variant

Q14156

Interaction Score

0.49

Q7Z656

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein DKFZp779C185

Q14156

Interaction Score

E7EMM1

(UniProtKB/TrEmbl/P) Details

Transmembrane protein 185A

Q14156

Interaction Score

B7Z4G6

(UniProtKB/TrEmbl/P) Details

Transmembrane protein 185A

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Q14156

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

Q14156

P23469

Receptor-type tyrosine-protein phosphatase epsilon

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q14156

Q99677

Lysophosphatidic acid receptor 4

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q14156

P12830

Cadherin-1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q14156

O75351

Vacuolar protein sorting-associated protein 4B

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q14156

Q15717

ELAV-like protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q14156

Q16288

NT-3 growth factor receptor

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q14156

O76081

Regulator of G-protein signaling 20

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q14156

P18827

Syndecan-1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q14156

Q92845

Kinesin-associated protein 3

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q14156

Q9UPP5

AP2-interacting clathrin-endocytosis protein

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q14156

Q8TD20

Solute carrier family 2, facilitated glucose transporter member 12

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q14156

Q9NT62

Ubiquitin-like-conjugating enzyme ATG3

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q14156