Q14CB8

Rho GTPase-activating protein 19 // UniProt Profile

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Species	H. sapiens
Number of Interactions	19 / 26
Average Interaction Score	0.946

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.958	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.958	Unknown: traceable author statement	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.958	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.981	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.981	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.981	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.981	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

Q14CB8

Interaction Score

Q96RT1

(UniProtKB/Swiss-Prot/P) Details

Erbin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.94	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nuclear membrane (GO:0031965)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.972	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.972	Experimental: experimental	MatrixDB	PubMed
Extracellular	Basement membrane (GO:0005604)	0.972	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Human Proteinpedia	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Basolateral plasma membrane (GO:0016323)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Basal plasma membrane (GO:0009925)	1	Unknown: non-traceable author statement	GO	PubMed
Membrane	Hemidesmosome (GO:0030056)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Neuromuscular junction (GO:0031594)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q14CB8

Interaction Score

P54252

(UniProtKB/Swiss-Prot/P) Details

Ataxin-3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.958	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.958	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.958	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial matrix (GO:0005759)	0.91	Predicted: inferred from sequence or structural similarity	GO	PubMed
Mitochondrion	Mitochondrial membrane (GO:0031966)	0.91	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear inclusion body (GO:0042405)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nuclear matrix (GO:0016363)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.8	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

IntAct, BioGRID, HPRD

Interaction Source Publication:

PubMed

Q14CB8

Interaction Score

P07948

(UniProtKB/Swiss-Prot/P) Details

Tyrosine-protein kinase Lyn

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial intermembrane space (GO:0005758)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Mitochondrion	Mitochondrial crista (GO:0030061)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.96	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Mast cell granule (GO:0042629)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic density (GO:0014069)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane raft (GO:0045121)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Extrinsic to internal side of plasma membrane (GO:0031234)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Alpha2-beta1 integrin complex (GO:0034666)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Cell-cell adherens junction (GO:0005913)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q14CB8

Interaction Score

P49789

(UniProtKB/Swiss-Prot/P) Details

Bis(5'-adenosyl)-triphosphatase

Q14CB8

Interaction Score

0.999

Q15717

(UniProtKB/Swiss-Prot/P) Details

ELAV-like protein 1

Q14CB8

Interaction Score

0.999

Q9H4P4

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase NRDP1

Q14CB8

Interaction Score

0.999

Q14644

(UniProtKB/Swiss-Prot/P) Details

Ras GTPase-activating protein 3

Q14CB8

Interaction Score

0.999

Q9H5V7

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein Pegasus

Q14CB8

Interaction Score

0.997

Q9Y3M2

(UniProtKB/Swiss-Prot/P) Details

Protein chibby homolog 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.86	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.999	Unknown: traceable author statement	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.988	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.988	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Trans-Golgi network (GO:0005802)	0.988	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centriole (GO:0005814)	0.86	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell projection (GO:0042995)	0.3	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed

Q14CB8

Interaction Score

0.996

P98164

(UniProtKB/Swiss-Prot/P) Details

Low-density lipoprotein receptor-related protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Coated pit (GO:0005905)	0.952	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.952	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.832	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.832	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endosome lumen (GO:0031904)	0.832	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Lysosome (GO:0005764)	0.952	Unknown: traceable author statement	GO	PubMed
Cytosol	Lysosomal membrane (GO:0005765)	0.952	Unknown: HDA	GO	PubMed
Secretory-pathway	Endocytic vesicle (GO:0030139)	0.832	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Clathrin coated vesicle membrane (GO:0030665)	0.832	Unknown: traceable author statement	GO	PubMed
Membrane	Brush border membrane (GO:0031526)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Dendrite (GO:0030425)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Axon (GO:0030424)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Unknown: traceable author statement	GO	PubMed
Membrane	External side of plasma membrane (GO:0009897)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Receptor complex (GO:0043235)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Apical plasma membrane (GO:0016324)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.952	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q14CB8

Interaction Score

0.996

Q9NXF7

(UniProtKB/Swiss-Prot/P) Details

DDB1- and CUL4-associated factor 16

Q14CB8

Interaction Score

0.995

Q8N1G4

(UniProtKB/Swiss-Prot/P) Details

Leucine-rich repeat-containing protein 47

Q14CB8

Interaction Score

0.987

A0A0A0MS38

(UniProtKB/TrEmbl/P) Details

Ataxin-3

Q14CB8

Interaction Score

0.987

C9JQV6

(UniProtKB/TrEmbl/P) Details

Ataxin-3

Q14CB8

Interaction Score

0.958

Q6NUK7

(UniProtKB/TrEmbl/P) Details

Tyrosine-protein kinase

Q14CB8

Interaction Score

0.958

Q9Y2W6

(UniProtKB/Swiss-Prot/P) Details

Tudor and KH domain-containing protein

Q14CB8

Interaction Score

0.768

Q01523

(UniProtKB/Swiss-Prot/P) Details

Defensin-5

Q14CB8

Interaction Score

0.672

Q7Z5C0

(UniProtKB/TrEmbl/P) Details

Glycoprotein receptor gp330/megalin

Q14CB8

Interaction Score

0.672

Q7Z5C1

(UniProtKB/TrEmbl/P) Details

Glycoprotein receptor gp330/megalin

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Q14CB8

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

Q14CB8

Q96RT1

Erbin

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q14CB8

P54252

Ataxin-3

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q14CB8

P07948

Tyrosine-protein kinase Lyn

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q14CB8

P49789

Bis(5'-adenosyl)-triphosphatase

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q14CB8

Q15717

ELAV-like protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q14CB8

Q9H4P4

E3 ubiquitin-protein ligase NRDP1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q14CB8

Q14644

Ras GTPase-activating protein 3

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q14CB8

Q9H5V7

Zinc finger protein Pegasus

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q14CB8

Q9Y3M2

Protein chibby homolog 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q14CB8

P98164

Low-density lipoprotein receptor-related protein 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q14CB8

Q9NXF7

DDB1- and CUL4-associated factor 16

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q14CB8

Q8N1G4

Leucine-rich repeat-containing protein 47

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q14CB8