Q16445

Gamma-aminobutyric acid receptor subunit alpha-6 // UniProt Profile

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Species	H. sapiens
Number of Interactions	13 / 19
Average Interaction Score	0.909

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Chloride channel complex (GO:0034707)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Predicted: pTarget method	LOCATE	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	0.999	Unknown: traceable author statement	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic membrane (GO:0045211)	0.999	Unknown: inferred from electronic annotation	GO	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

Q16445

Interaction Score

P28472

(UniProtKB/Swiss-Prot/P) Details

Gamma-aminobutyric acid receptor subunit beta-3

Q16445

Interaction Score

0.999

Q9NZN4

(UniProtKB/Swiss-Prot/P) Details

EH domain-containing protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.86	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.86	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Recycling endosome membrane (GO:0055038)	0.86	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endosome membrane (GO:0010008)	0.86	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	0.999	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.96	Experimental: experimental	MatrixDB	PubMed
Extracellular	Intercellular bridge (GO:0045171)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Extrinsic to membrane (GO:0019898)	0.996	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.996	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Caveola (GO:0005901)	0.996	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.999	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q16445

Interaction Score

0.997

Q93084

(UniProtKB/Swiss-Prot/P) Details

Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Sarcoplasmic reticulum (GO:0016529)	0.902	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Sarcoplasmic reticulum membrane (GO:0033017)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Platelet dense tubular network membrane (GO:0031095)	0.902	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.972	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.972	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nuclear membrane (GO:0031965)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.992	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.992	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.992	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.992	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.992	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.992	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.992	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	0.992	Predicted: PAML algorithm	PA-GOSUB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q16445

Interaction Score

0.99

Q9H819

(UniProtKB/Swiss-Prot/P) Details

DnaJ homolog subfamily C member 18

Q16445

Interaction Score

0.964

Q96E35

(UniProtKB/Swiss-Prot/P) Details

Zinc finger MYND domain-containing protein 19

Q16445

Interaction Score

0.964

Q8NEN9

(UniProtKB/Swiss-Prot/P) Details

PDZ domain-containing protein 8

Q16445

Interaction Score

0.949

P04035

(UniProtKB/Swiss-Prot/P) Details

3-hydroxy-3-methylglutaryl-coenzyme A reductase

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endomembrane system (GO:0012505)	0.992	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.998	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.998	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.998	Unknown: traceable author statement	GO	PubMed
Cytosol	Peroxisome (GO:0005777)	0.992	Experimental: experimental	eSLDB	PubMed
Cytosol	Peroxisomal membrane (GO:0005778)	0.992	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.86	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.86	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q16445

Interaction Score

0.928

Q9UMX0

(UniProtKB/Swiss-Prot/P) Details

Ubiquilin-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Aggresome (GO:0016235)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Proteasome complex (GO:0000502)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Unknown: non-traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.86	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Autophagic vacuole (GO:0005776)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.8	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q16445

Interaction Score

0.924

Q8TDW4

(UniProtKB/Swiss-Prot/P) Details

Suppressor of tumorigenicity 7 protein-like

Q16445

Interaction Score

0.924

Q9H6A9

(UniProtKB/Swiss-Prot/P) Details

Pecanex-like protein 3

Q16445

Interaction Score

0.892

Q96G97

(UniProtKB/Swiss-Prot/P) Details

Seipin

Q16445

Interaction Score

0.64

A8K9K1

(UniProtKB/TrEmbl/P) Details

Calcium-transporting ATPase

Q16445

Interaction Score

0.64

A0A024RAP2

(UniProtKB/TrEmbl/P) Details

3-hydroxy-3-methylglutaryl coenzyme A reductase

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Q16445

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

Q16445

P28472

Gamma-aminobutyric acid receptor subunit beta-3

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q16445

Q9NZN4

EH domain-containing protein 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q16445

Q93084

Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q16445

Q9H819

DnaJ homolog subfamily C member 18

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q16445

Q96E35

Zinc finger MYND domain-containing protein 19

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q16445

Q8NEN9

PDZ domain-containing protein 8

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q16445

P04035

3-hydroxy-3-methylglutaryl-coenzyme A reductase

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q16445

Q9UMX0

Ubiquilin-1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q16445

Q8TDW4

Suppressor of tumorigenicity 7 protein-like

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q16445

Q9H6A9

Pecanex-like protein 3

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q16445

Q96G97

Seipin

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q16445

A8K9K1

Calcium-transporting ATPase

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q16445