Q16559

T-cell acute lymphocytic leukemia protein 2 // UniProt Profile

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Species	H. sapiens
Number of Interactions	18 / 25
Average Interaction Score	0.932

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.973	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.973	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.973	Predicted: PAML algorithm	PA-GOSUB	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

Q16559

Interaction Score

0.994

Q99081

(UniProtKB/Swiss-Prot/P) Details

Transcription factor 12

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.992	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.992	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	RNA polymerase II transcription factor complex (GO:0090575)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear chromatin (GO:0000790)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q16559

Interaction Score

0.994

P15884

(UniProtKB/Swiss-Prot/P) Details

Transcription factor 4

Q16559

Interaction Score

0.993

P27361

(UniProtKB/Swiss-Prot/P) Details

Mitogen-activated protein kinase 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.987	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.987	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.987	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.987	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.3	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nuclear envelope (GO:0005635)	0.996	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.996	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.657	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	0.657	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Late endosome (GO:0005770)	0.657	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.987	Unknown: traceable author statement	GO	PubMed
Membrane	Pseudopodium (GO:0031143)	0.956	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.956	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Caveola (GO:0005901)	0.956	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.956	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

Q16559

Interaction Score

0.99

P15923

(UniProtKB/Swiss-Prot/P) Details

Transcription factor E2-alpha

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.8	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Transcription factor complex (GO:0005667)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	RNA polymerase II transcription factor complex (GO:0090575)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear chromatin (GO:0000790)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

Q16559

Interaction Score

0.99

P25791

(UniProtKB/Swiss-Prot/P) Details

Rhombotin-2

Q16559

Interaction Score

0.973

Q06455

(UniProtKB/Swiss-Prot/P) Details

Protein CBFA2T1

Q16559

Interaction Score

0.973

O43439

(UniProtKB/Swiss-Prot/P) Details

Protein CBFA2T2

Q16559

Interaction Score

0.941

Q9H0N5

(UniProtKB/Swiss-Prot/P) Details

Pterin-4-alpha-carbinolamine dehydratase 2

Q16559

Interaction Score

0.934

F5GY10

(UniProtKB/TrEmbl/P) Details

Transcription factor 12

Q16559

Interaction Score

0.92

E9PH57

(UniProtKB/TrEmbl/P) Details

Transcription factor 4, isoform CRA_e

Q16559

Interaction Score

0.92

H3BPJ7

(UniProtKB/TrEmbl/P) Details

Transcription factor 4

Q16559

Interaction Score

0.92

H3BTP3

(UniProtKB/TrEmbl/P) Details

Transcription factor 4

Q16559

Interaction Score

0.92

A0A1B0GWD5

(UniProtKB/TrEmbl/P) Details

Transcription factor 4

Q16559

Interaction Score

0.92

A0A1B0GW91

(UniProtKB/TrEmbl/P) Details

Transcription factor 4

Q16559

Interaction Score

0.92

A0A1B0GVR6

(UniProtKB/TrEmbl/P) Details

Transcription factor 4

Q16559

Interaction Score

0.912

P25800

(UniProtKB/Swiss-Prot/P) Details

Rhombotin-1

Q16559

Interaction Score

0.778

A0A0A0MSU1

(UniProtKB/TrEmbl/P) Details

Protein CBFA2T1

Q16559

Interaction Score

0.778

A0A087WWT6

(UniProtKB/TrEmbl/P) Details

Protein CBFA2T1

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Q16559

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

Q16559

Q99081

Transcription factor 12

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q16559

P15884

Transcription factor 4

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q16559

P27361

Mitogen-activated protein kinase 3

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q16559

P15923

Transcription factor E2-alpha

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q16559

P25791

Rhombotin-2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q16559

Q06455

Protein CBFA2T1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q16559

O43439

Protein CBFA2T2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q16559

Q9H0N5

Pterin-4-alpha-carbinolamine dehydratase 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q16559

F5GY10

Transcription factor 12

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q16559

E9PH57

Transcription factor 4, isoform CRA_e

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q16559

H3BPJ7

Transcription factor 4

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q16559

H3BTP3

Transcription factor 4

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q16559