Q2NKJ3

CST complex subunit CTC1    //   UniProt Profile 

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Species

 H. sapiens

Number of Interactions

 17 / 23

Average Interaction Score

 0.629

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.982 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.982 Predicted: inferred from sequence or structural similarity GO PubMed 
Nucleus Nuclear chromosome, telomeric region (GO:0000784) 0.982 Experimental: inferred from direct assay GO PubMed 

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

Q2NKJ3

Interaction Score
0.982

Q12888

(UniProtKB/Swiss-Prot/P) Details

TP53-binding protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.96 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.96 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Human Proteinpedia PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nuclear body (GO:0016604) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear body (GO:0016604) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Site of double-strand break (GO:0035861) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear chromosome, telomeric region (GO:0000784) 1 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Replication fork (GO:0005657) 1 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Condensed chromosome kinetochore (GO:0000777) 1 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Chromosome, telomeric region (GO:0000781) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q2NKJ3

Interaction Score
0.982

P38398

(UniProtKB/Swiss-Prot/P) Details

Breast cancer type 1 susceptibility protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Ubiquitin ligase complex (GO:0000151) 0.996 Unknown: non-traceable author statement GO PubMed 
Cytosol Ubiquitin ligase complex (GO:0000151) 0.996 Experimental: experimental Organelle PubMed 
Cytosol Cytoplasm (GO:0005737) 0.996 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Unknown: traceable author statement GO PubMed 
Nucleus Macromolecular complex (GO:0032991) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus BRCA1-A complex (GO:0070531) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus BRCA1-BARD1 complex (GO:0031436) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 0.996 Experimental: experimental Organelle PubMed 
Cytosol Gamma-tubulin ring complex (GO:0008274) 0.996 Unknown: non-traceable author statement GO PubMed 
Nucleus Chromosome (GO:0005694) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Nucleus Lateral element (GO:0000800) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.8 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q2NKJ3

Interaction Score
0.982

Q9NUX5

(UniProtKB/Swiss-Prot/P) Details

Protection of telomeres protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Unknown: traceable author statement GO PubMed 
Nucleus Nuclear telomere cap complex (GO:0000783) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Telosome (GO:0070187) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear chromosome, telomeric region (GO:0000784) 1 Unknown: HDA GO PubMed 
Nucleus Chromosome, telomeric region (GO:0000781) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

DIP

Interaction Source Publication:

PubMed 

Q2NKJ3

Interaction Score
0.982

Q14258

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin/ISG15 ligase TRIM25

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.988 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.988 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.988 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nuclear body (GO:0016604) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear body (GO:0016604) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q2NKJ3

Interaction Score
0.981

Q01664

(UniProtKB/Swiss-Prot/P) Details

Transcription factor AP-4

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Mitochondrion Mitochondrion (GO:0005739) 0.96 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.999 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.999 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.999 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Transcriptional repressor complex (GO:0017053) 0.999 Predicted: inferred from sequence or structural similarity GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q2NKJ3

Interaction Score
0.981

O75496

(UniProtKB/Swiss-Prot/P) Details

Geminin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.96 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.96 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.999 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.999 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.999 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 0.999 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.999 Unknown: traceable author statement GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q2NKJ3

Interaction Score
0.98

Q9H668

(UniProtKB/Swiss-Prot/P) Details

CST complex subunit STN1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.988 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.988 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.998 Predicted: inferred from sequence or structural similarity GO PubMed 
Nucleus Nucleus (GO:0005634) 0.998 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Fibrillar center (GO:0001650) 0.998 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.998 Experimental: inferred from direct assay GO PubMed 
Cytosol Intermediate filament cytoskeleton (GO:0045111) 0.988 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear chromosome, telomeric region (GO:0000784) 0.998 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID, IntAct, DIP

Interaction Source Publication:

PubMed , PubMed , PubMed 

Q2NKJ3

Interaction Score
0.974

Q92624

(UniProtKB/Swiss-Prot/P) Details

Amyloid protein-binding protein 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.999 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Unknown: non-traceable author statement GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Unknown: non-traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Cytoplasmic vesicle membrane (GO:0030659) 0.8 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 0.999 Experimental: experimental eSLDB PubMed 
Cytosol Cytoskeleton (GO:0005856) 0.999 Experimental: experimental Organelle PubMed 
Cytosol Microtubule associated complex (GO:0005875) 0.999 Unknown: traceable author statement GO PubMed 
Cytosol Microtubule (GO:0005874) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental eSLDB PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

Q2NKJ3

Interaction Score
0.963

Q5VWX1

(UniProtKB/Swiss-Prot/P) Details

KH domain-containing, RNA-binding, signal transduction-associated protein 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.981 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.981 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 0.981 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.981 Unknown: traceable author statement GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q2NKJ3

Interaction Score
0.943

Q99615

(UniProtKB/Swiss-Prot/P) Details

DnaJ homolog subfamily C member 7

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.96 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.3 Unknown: HDA GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q2NKJ3

Interaction Score
0.943

Q86WV5

(UniProtKB/Swiss-Prot/P) Details

CST complex subunit TEN1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.96 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear chromosome, telomeric region (GO:0000784) 0.96 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct, DIP, BioGRID

Interaction Source Publication:

PubMed , PubMed , PubMed 

Q2NKJ3

Interaction Score
0

O14773

(UniProtKB/Swiss-Prot/P) Details

Tripeptidyl-peptidase 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Lysosome (GO:0005764) 0.994 Experimental: experimental eSLDB PubMed 
Cytosol Lysosome (GO:0005764) 0.994 Experimental: inferred from direct assay GO PubMed 
Cytosol Lysosome (GO:0005764) 0.994 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Lysosomal lumen (GO:0043202) 0.994 Unknown: traceable author statement GO PubMed 
Secretory-pathway Melanosome (GO:0042470) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.994 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID, DIP

Interaction Source Publication:

PubMed , PubMed 

Q2NKJ3

Interaction Score
0

Q9UF02

(UniProtKB/Swiss-Prot/P) Details

Voltage-dependent calcium channel gamma-5 subunit

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Postsynaptic density (GO:0014069) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Experimental: experimental eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 1 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: pTarget method LOCATE PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex (GO:0032281) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Cell junction (GO:0030054) 1 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q2NKJ3

Interaction Score
0

Q9BRK4

(UniProtKB/Swiss-Prot/P) Details

Leucine zipper putative tumor suppressor 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Midbody (GO:0030496) 0.972 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Centrosome (GO:0005813) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Microtubule (GO:0005874) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.972 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.972 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Vesicle (GO:0031982) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q2NKJ3

Interaction Score
0

Q99435

(UniProtKB/Swiss-Prot/P) Details

Protein kinase C-binding protein NELL2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.8 Experimental: experimental eSLDB PubMed 
Cytosol Cell (GO:0005623) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.86 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular matrix (GO:0031012) 0.958 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q2NKJ3

Interaction Score
0

Q9Y2B0

(UniProtKB/Swiss-Prot/P) Details

Protein canopy homolog 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.91 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.91 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.8 Experimental: experimental Organelle PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q2NKJ3

Interaction Score
0

Q8N5Z5

(UniProtKB/Swiss-Prot/P) Details

BTB/POZ domain-containing protein KCTD17

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cul3-RING ubiquitin ligase complex (GO:0031463) 0.988 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.988 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.988 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.3 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

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ComPPI is published in Nucleic Acids Research Database Issue 2015