Q2Q1W2

E3 ubiquitin-protein ligase TRIM71 // UniProt Profile

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Species	H. sapiens
Number of Interactions	21 / 24
Average Interaction Score	0.704

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.982	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasmic mRNA processing body (GO:0000932)	0.982	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	0.982	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Focal adhesion (GO:0005925)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

Q2Q1W2

Interaction Score

0.999

Q9UKV8

(UniProtKB/Swiss-Prot/P) Details

Protein argonaute-2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	RISC-loading complex (GO:0070578)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	RNA-induced silencing complex (GO:0016442)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Polysome (GO:0005844)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasmic mRNA processing body (GO:0000932)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Micro-ribonucleoprotein complex (GO:0035068)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	MRNA cap binding complex (GO:0005845)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Unknown: inferred by curator	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.992	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Dendrite (GO:0030425)	0.98	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.98	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.98	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.98	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q2Q1W2

Interaction Score

0.998

O60296

(UniProtKB/Swiss-Prot/P) Details

Trafficking kinesin-binding protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Neuronal cell body (GO:0043025)	0.992	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.992	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.992	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.997	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.997	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.997	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear body (GO:0016604)	0.997	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Early endosome (GO:0005769)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendrite cytoplasm (GO:0032839)	0.971	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Axonal growth cone (GO:0044295)	0.971	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.971	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.971	Experimental: experimental	Organelle	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q2Q1W2

Interaction Score

0.991

Q9UPY3

(UniProtKB/Swiss-Prot/P) Details

Endoribonuclease Dicer

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	RISC-loading complex (GO:0070578)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	RNA-induced silencing complex (GO:0016442)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Micro-ribonucleoprotein complex (GO:0035068)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.973	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.973	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.973	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum-Golgi intermediate compartment (GO:0005793)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Lysosome (GO:0005764)	1	Predicted: pTarget method	LOCATE	PubMed
Membrane	Growth cone (GO:0030426)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendrite (GO:0030425)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q2Q1W2

Interaction Score

0.981

Q9H9Z2

(UniProtKB/Swiss-Prot/P) Details

Protein lin-28 homolog A

Q2Q1W2

Interaction Score

0.955

O15213

(UniProtKB/Swiss-Prot/P) Details

WD repeat-containing protein 46

Q2Q1W2

Interaction Score

0.955

Q9NZM5

(UniProtKB/Swiss-Prot/P) Details

Ribosome biogenesis protein NOP53

Q2Q1W2

Interaction Score

0.943

Q6ZN17

(UniProtKB/Swiss-Prot/P) Details

Protein lin-28 homolog B

Q2Q1W2

Interaction Score

0.923

Q6AW86

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein 324B

Q2Q1W2

Interaction Score

0.877

P55075

(UniProtKB/Swiss-Prot/P) Details

Fibroblast growth factor 8

Q2Q1W2

Interaction Score

0.786

A0A1B0GVD3

(UniProtKB/TrEmbl/P) Details

Protein lin-28 homolog B

Q2Q1W2

Interaction Score

0.786

Q5VWQ0

(UniProtKB/Swiss-Prot/P) Details

Lysine-specific demethylase 9

Q2Q1W2

Interaction Score

0.768

A1A515

(UniProtKB/TrEmbl/P) Details

Fibroblast growth factor

Q2Q1W2

Interaction Score

0.768

A0A087X1S5

(UniProtKB/TrEmbl/P) Details

Fibroblast growth factor

Q2Q1W2

Interaction Score

0.687

Q15050

(UniProtKB/Swiss-Prot/P) Details

Ribosome biogenesis regulatory protein homolog

Q2Q1W2

Interaction Score

0.687

P10412

(UniProtKB/Swiss-Prot/P) Details

Histone H1.4

Q2Q1W2

Interaction Score

0.687

A3R0T8

(UniProtKB/TrEmbl/P) Details

Histone 1, H1e

Q2Q1W2

Interaction Score

0.501

Q66K89

(UniProtKB/Swiss-Prot/P) Details

Transcription factor E4F1

Q2Q1W2

Interaction Score

0.498

Q02539

(UniProtKB/Swiss-Prot/P) Details

Histone H1.1

Q2Q1W2

Interaction Score

Q9H0W7

(UniProtKB/Swiss-Prot/P) Details

THAP domain-containing protein 2

Q2Q1W2

Interaction Score

P47902

(UniProtKB/Swiss-Prot/P) Details

Homeobox protein CDX-1

Q2Q1W2

Interaction Score

A1L190

(UniProtKB/Swiss-Prot/P) Details

Synaptonemal complex central element protein 3

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Q2Q1W2

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

Q2Q1W2

Q9UKV8

Protein argonaute-2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q2Q1W2

O60296

Trafficking kinesin-binding protein 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q2Q1W2

Q9UPY3

Endoribonuclease Dicer

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q2Q1W2

Q9H9Z2

Protein lin-28 homolog A

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q2Q1W2

O15213

WD repeat-containing protein 46

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q2Q1W2

Q9NZM5

Ribosome biogenesis protein NOP53

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q2Q1W2

Q6ZN17

Protein lin-28 homolog B

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q2Q1W2

Q6AW86

Zinc finger protein 324B

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q2Q1W2

P55075

Fibroblast growth factor 8

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q2Q1W2

A0A1B0GVD3

Protein lin-28 homolog B

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q2Q1W2

Q5VWQ0

Lysine-specific demethylase 9

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q2Q1W2

A1A515

Fibroblast growth factor

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q2Q1W2