Q5JQC9

A-kinase anchor protein 4 // UniProt Profile

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Species	H. sapiens
Number of Interactions	7 / 13
Average Interaction Score	0.935

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.986	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.986	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	CAMP-dependent protein kinase complex (GO:0005952)	0.986	Unknown: non-traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.79	Unknown: HDA	GO	PubMed
Cytosol	Z disc (GO:0030018)	0.986	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.986	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.986	Experimental: experimental	Organelle	PubMed
Membrane	Sperm fibrous sheath (GO:0035686)	0.982	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Motile cilium (GO:0031514)	0.982	Experimental: inferred from direct assay	GO	PubMed
Membrane	Sperm principal piece (GO:0097228)	0.982	Predicted: inferred from biological aspect of ancestor	GO	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

Q5JQC9

Interaction Score

P13861

(UniProtKB/Swiss-Prot/P) Details

cAMP-dependent protein kinase type II-alpha regulatory subunit

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	CAMP-dependent protein kinase complex (GO:0005952)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	AMP-activated protein kinase complex (GO:0031588)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.8	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Axoneme (GO:0005930)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Ciliary base (GO:0097546)	0.986	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.986	Unknown: HDA	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.986	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.986	Experimental: experimental	Organelle	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.986	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q5JQC9

Interaction Score

P10644

(UniProtKB/Swiss-Prot/P) Details

cAMP-dependent protein kinase type I-alpha regulatory subunit

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	CAMP-dependent protein kinase complex (GO:0005952)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	AMP-activated protein kinase complex (GO:0031588)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Axoneme (GO:0005930)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Ciliary base (GO:0097546)	0.931	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.931	Unknown: HDA	GO	PubMed
Membrane	Immunological synapse (GO:0001772)	0.931	Experimental: inferred from direct assay	GO	PubMed
Membrane	Neuromuscular junction (GO:0031594)	0.931	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

HPRD, BioGRID

Interaction Source Publication:

PubMed

, PubMed

Q5JQC9

Interaction Score

0.999

P36873

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Midbody (GO:0030496)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Protein phosphatase type 1 complex (GO:0000164)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	PTW/PP1 phosphatase complex (GO:0072357)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cleavage furrow (GO:0032154)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.86	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial outer membrane (GO:0005741)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.999	Experimental: inferred from mutant phenotype	GO	PubMed
Nucleus	Nuclear chromosome, telomeric region (GO:0000784)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Condensed chromosome kinetochore (GO:0000777)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendritic spine (GO:0043197)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.657	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q5JQC9

Interaction Score

0.991

O75969

(UniProtKB/Swiss-Prot/P) Details

A-kinase anchor protein 3

Q5JQC9

Interaction Score

0.991

Q5CZC0

(UniProtKB/Swiss-Prot/P) Details

Fibrous sheath-interacting protein 2

Q5JQC9

Interaction Score

0.788

B3KY43

(UniProtKB/TrEmbl/P) Details

cDNA FLJ46798 fis, clone TRACH3031660, highly similar to cAMP-dependent protein kinase type II-beta regulatory subunit

Q5JQC9

Interaction Score

0.775

Q8NA03

(UniProtKB/Swiss-Prot/P) Details

Fibrous sheath-interacting protein 1

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Q5JQC9

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

Q5JQC9

P13861

cAMP-dependent protein kinase type II-alpha regulatory subunit

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q5JQC9

P10644

cAMP-dependent protein kinase type I-alpha regulatory subunit

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q5JQC9

P36873

Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q5JQC9

O75969

A-kinase anchor protein 3

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q5JQC9

Q5CZC0

Fibrous sheath-interacting protein 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q5JQC9

B3KY43

cDNA FLJ46798 fis, clone TRACH3031660, highly similar to cAMP-dependent protein kinase type II-beta regulatory subunit

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q5JQC9

Q8NA03

Fibrous sheath-interacting protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication: