Q6T775

Kallikrein 2 isoform 5 preproprotein // UniProt Profile

Custom Settings: Use these controls to filter the data displayed on this page. The parameters apply to both the query protein and its interactors. Details

The (filtered) results are available for download, see the help for details. Download The Results

Species	H. sapiens
Number of Interactions	13 / 13
Average Interaction Score	0.73

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed

First-Neighbour Network Visualization

Toggle Display

The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

Q6T775

Interaction Score

0.907

P05154

(UniProtKB/Swiss-Prot/P) Details

Plasma serine protease inhibitor

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.988	Predicted: SVM decision tree	eSLDB	PubMed
Extracellular	Protein C inhibitor-coagulation factor V complex (GO:0097181)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Protein C inhibitor-coagulation factor Xa complex (GO:0097182)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Protein C inhibitor-coagulation factor XI complex (GO:0097183)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Protein C inhibitor-KLK3 complex (GO:0036029)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Protein C inhibitor-plasma kallikrein complex (GO:0036030)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Protein C inhibitor-PLAT complex (GO:0036026)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Protein C inhibitor-PLAU complex (GO:0036027)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Protein C inhibitor-thrombin complex (GO:0036028)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Protein C inhibitor-TMPRSS11E complex (GO:0036025)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Protein C inhibitor-TMPRSS7 complex (GO:0036024)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Platelet dense tubular network (GO:0031094)	0.86	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.8	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Platelet alpha granule (GO:0031091)	0.988	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Acrosomal membrane (GO:0002080)	0.988	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	1	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	1	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Membrane (GO:0016020)	0.992	Experimental: inferred from direct assay	GO	PubMed
Membrane	Membrane (GO:0016020)	0.992	Experimental: experimental	MatrixDB	PubMed
Membrane	External side of plasma membrane (GO:0009897)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.86	Unknown: HDA	GO	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

Q6T775

Interaction Score

0.901

P18065

(UniProtKB/Swiss-Prot/P) Details

Insulin-like growth factor-binding protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.958	Predicted: SVM decision tree	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.958	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.958	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.999	Predicted: pTarget method	LOCATE	PubMed
Extracellular	Extracellular region (GO:0005576)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.999	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.999	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.86	Experimental: experimental	MatrixDB	PubMed
Membrane	Apical plasma membrane (GO:0016324)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

Q6T775

Interaction Score

0.88

P05121

(UniProtKB/Swiss-Prot/P) Details

Plasminogen activator inhibitor 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.86	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.992	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Platelet alpha granule lumen (GO:0031093)	0.86	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.998	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.998	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.998	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.86	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.86	Unknown: traceable author statement	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.992	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

Q6T775

Interaction Score

0.875

P01008

(UniProtKB/Swiss-Prot/P) Details

Antithrombin-III

Q6T775

Interaction Score

0.871

P01011

(UniProtKB/Swiss-Prot/P) Details

Alpha-1-antichymotrypsin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.931	Experimental: experimental	eSLDB	PubMed
Cytosol	Intracellular (GO:0005622)	0.902	Unknown: non-traceable author statement	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.902	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	0.3	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Secretory granule lumen (GO:0034774)	0.931	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Platelet alpha granule lumen (GO:0031093)	0.931	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Azurophil granule lumen (GO:0035578)	0.931	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.897	Unknown: non-traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.897	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.897	Unknown: HDA	GO	PubMed
Extracellular	Blood microparticle (GO:0072562)	0.897	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	MatrixDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.902	Unknown: HDA	GO	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

Q6T775

Interaction Score

0.864

P08697

(UniProtKB/Swiss-Prot/P) Details

Alpha-2-antiplasmin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Cell surface (GO:0009986)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.51	Unknown: unspecified method	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.3	Unknown: unspecified method	The Human Protein Atlas	PubMed
Secretory-pathway	Platelet alpha granule lumen (GO:0031093)	0.79	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.994	Unknown: non-traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.994	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.994	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Fibrinogen complex (GO:0005577)	0.994	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Blood microparticle (GO:0072562)	0.994	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.96	Experimental: experimental	MatrixDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.51	Unknown: HDA	GO	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

Serpin B6

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Extracellular	Serine protease inhibitor complex (GO:0097180)	0.987	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Secretory granule membrane (GO:0030667)	0.51	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Tertiary granule membrane (GO:0070821)	0.51	Unknown: traceable author statement	GO	PubMed
Cytosol	Centrosome (GO:0005813)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.987	Unknown: HDA	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.987	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.987	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Membrane (GO:0016020)	0.86	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.86	Unknown: traceable author statement	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.999	Unknown: HDA	GO	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

Q6T775

Interaction Score

P10275

(UniProtKB/Swiss-Prot/P) Details

Androgen receptor

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.86	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.86	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear chromatin (GO:0000790)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.3	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

Q6T775

Interaction Score

P24928

(UniProtKB/Swiss-Prot/P) Details

DNA-directed RNA polymerase II subunit RPB1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Prp19 complex (GO:0000974)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	DNA-directed RNA polymerase II, core complex (GO:0005665)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	RNA polymerase complex (GO:0030880)	1	Experimental: experimental	Organelle	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

⇦ Back to the Search Page
⇦ Back to Starting Page

Q6T775

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

Q6T775

P05154

Plasma serine protease inhibitor

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q6T775

P18065

Insulin-like growth factor-binding protein 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q6T775

P05121

Plasminogen activator inhibitor 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q6T775

P01008

Antithrombin-III

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q6T775

P01011

Alpha-1-antichymotrypsin

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q6T775

P08697

Alpha-2-antiplasmin

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q6T775

P29622

Kallistatin

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q6T775

P01023

Alpha-2-macroglobulin

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q6T775

Q02383

Semenogelin-2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q6T775

P04279

Semenogelin-1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q6T775

P35237

Serpin B6

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q6T775

P10275

Androgen receptor

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q6T775