Q6ZMB5

Transmembrane protein 184A // UniProt Profile

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Species	H. sapiens
Number of Interactions	53 / 75
Average Interaction Score	0.721

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.7	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.994	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Early endosome membrane (GO:0031901)	0.994	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle membrane (GO:0030659)	0.994	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Secretory granule membrane (GO:0030667)	0.994	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Transport vesicle membrane (GO:0030658)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.992	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.992	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.992	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.992	Predicted: pTarget method	LOCATE	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

Q6ZMB5

Interaction Score

Q03135

(UniProtKB/Swiss-Prot/P) Details

Caveolin-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endomembrane system (GO:0012505)	0.994	Experimental: experimental	Organelle	PubMed
Cytosol	Intracellular (GO:0005622)	0.994	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Lipid particle (GO:0005811)	0.994	Unknown: traceable author statement	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.994	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cell cortex (GO:0005938)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.8	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Cdc48p-Npl4p-Ufd1p AAA ATPase complex (GO:0034098)	1	Predicted: inferred from physical interaction	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Early endosome membrane (GO:0031901)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endocytic vesicle membrane (GO:0030666)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Acrosomal membrane (GO:0002080)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Cilium (GO:0005929)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Membrane raft (GO:0045121)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Human Proteinpedia	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Caveola (GO:0005901)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q6ZMB5

Interaction Score

0.999

P55196

(UniProtKB/Swiss-Prot/P) Details

Afadin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.94	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytosol (GO:0005829)	0.94	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.998	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Cell junction (GO:0030054)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Cell-cell junction (GO:0005911)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Cell-cell adherens junction (GO:0005913)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q6ZMB5

Interaction Score

0.998

Q9UHR4

(UniProtKB/Swiss-Prot/P) Details

Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1

Q6ZMB5

Interaction Score

0.994

J3KN01

(UniProtKB/TrEmbl/P) Details

Afadin

Q6ZMB5

Interaction Score

0.988

A8MQ02

(UniProtKB/TrEmbl/P) Details

Afadin

Q6ZMB5

Interaction Score

0.986

Q6P996

(UniProtKB/Swiss-Prot/P) Details

Pyridoxal-dependent decarboxylase domain-containing protein 1

Q6ZMB5

Interaction Score

0.986

Q9BTE3

(UniProtKB/Swiss-Prot/P) Details

Mini-chromosome maintenance complex-binding protein

Q6ZMB5

Interaction Score

0.985

P14866

(UniProtKB/Swiss-Prot/P) Details

Heterogeneous nuclear ribonucleoprotein L

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Ribonucleoprotein complex (GO:0030529)	0.999	Experimental: experimental	Organelle	PubMed
Cytosol	Ribonucleoprotein granule (GO:0035770)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.999	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q6ZMB5

Interaction Score

0.983

Q96N66

(UniProtKB/Swiss-Prot/P) Details

Lysophospholipid acyltransferase 7

Q6ZMB5

Interaction Score

0.978

P34897

(UniProtKB/Swiss-Prot/P) Details

Serine hydroxymethyltransferase, mitochondrial

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial matrix (GO:0005759)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial nucleoid (GO:0042645)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial intermembrane space (GO:0005758)	1	Unknown: inferred from electronic annotation	GO	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	BRISC complex (GO:0070552)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.998	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q6ZMB5

Interaction Score

0.967

P00966

(UniProtKB/Swiss-Prot/P) Details

Argininosuccinate synthase

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Myelin sheath (GO:0043209)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Perikaryon (GO:0043204)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial outer membrane (GO:0005741)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.86	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Lysosome (GO:0005764)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Cell body fiber (GO:0070852)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.997	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q6ZMB5

Interaction Score

0.962

Q96SI1

(UniProtKB/Swiss-Prot/P) Details

BTB/POZ domain-containing protein KCTD15

Q6ZMB5

Interaction Score

0.953

Q9HCE1

(UniProtKB/Swiss-Prot/P) Details

Putative helicase MOV-10

Q6ZMB5

Interaction Score

0.939

Q96PM5

(UniProtKB/Swiss-Prot/P) Details

RING finger and CHY zinc finger domain-containing protein 1

Q6ZMB5

Interaction Score

0.938

Q14258

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin/ISG15 ligase TRIM25

Q6ZMB5

Interaction Score

0.938

P13984

(UniProtKB/Swiss-Prot/P) Details

General transcription factor IIF subunit 2

Q6ZMB5

Interaction Score

0.93

Q86XE2

(UniProtKB/TrEmbl/P) Details

PDXDC1 protein

Q6ZMB5

Interaction Score

0.93

Q6XYB5

(UniProtKB/TrEmbl/P) Details

LP8165

Q6ZMB5

Interaction Score

0.923

Q9H0Z9

(UniProtKB/Swiss-Prot/P) Details

RNA-binding protein 38

Q6ZMB5

Interaction Score

0.916

Q9Y2Z4

(UniProtKB/Swiss-Prot/P) Details

Tyrosine--tRNA ligase, mitochondrial

Q6ZMB5

Interaction Score

0.91

H3BND4

(UniProtKB/TrEmbl/P) Details

Pyridoxal-dependent decarboxylase domain-containing protein 1

Q6ZMB5

Interaction Score

0.906

Q9H1K1

(UniProtKB/Swiss-Prot/P) Details

Iron-sulfur cluster assembly enzyme ISCU, mitochondrial

Q6ZMB5

Interaction Score

0.89

Q7Z4F3

(UniProtKB/TrEmbl/P) Details

Caveolin

Q6ZMB5

Interaction Score

0.89

Q59E85

(UniProtKB/TrEmbl/P) Details

Caveolin

Q6ZMB5

Interaction Score

0.89

Q2TNI1

(UniProtKB/TrEmbl/P) Details

Caveolin

Q6ZMB5

Interaction Score

0.844

Q4G176

(UniProtKB/Swiss-Prot/P) Details

Acyl-CoA synthetase family member 3, mitochondrial

Q6ZMB5

Interaction Score

0.839

P23921

(UniProtKB/Swiss-Prot/P) Details

Ribonucleoside-diphosphate reductase large subunit

Q6ZMB5

Interaction Score

0.816

Q6NVY1

(UniProtKB/Swiss-Prot/P) Details

3-hydroxyisobutyryl-CoA hydrolase, mitochondrial

Q6ZMB5

Interaction Score

0.8

O43847

(UniProtKB/Swiss-Prot/P) Details

Nardilysin

Q6ZMB5

Interaction Score

0.797

Q9BY42

(UniProtKB/Swiss-Prot/P) Details

Protein RTF2 homolog

Q6ZMB5

Interaction Score

0.79

A0A0A0MQR2

(UniProtKB/TrEmbl/P) Details

Replication termination factor 2

Q6ZMB5

Interaction Score

0.768

A2A2L6

(UniProtKB/TrEmbl/P) Details

Replication termination factor 2

Q6ZMB5

Interaction Score

0.696

Q5U5X0

(UniProtKB/Swiss-Prot/P) Details

Complex III assembly factor LYRM7

Q6ZMB5

Interaction Score

0.694

F5H5A1

(UniProtKB/TrEmbl/P) Details

Acyl-CoA synthetase family member 3, mitochondrial

Q6ZMB5

Interaction Score

0.658

Q5JR04

(UniProtKB/TrEmbl/P) Details

Mov10, Moloney leukemia virus 10, homolog (Mouse), isoform CRA_a

Q6ZMB5

Interaction Score

0.64

A0A024R757

(UniProtKB/TrEmbl/P) Details

Caveolin

Q6ZMB5

Interaction Score

0.64

A9XTE5

(UniProtKB/TrEmbl/P) Details

Caveolin

Q6ZMB5

Interaction Score

0.64

B1AKJ5

(UniProtKB/TrEmbl/P) Details

Nardilysin (N-arginine dibasic convertase), isoform CRA_d

Q6ZMB5

Interaction Score

0.64

G3V1R5

(UniProtKB/TrEmbl/P) Details

Nardilysin (N-arginine dibasic convertase), isoform CRA_e

Q6ZMB5

Interaction Score

0.56

B4DNC9

(UniProtKB/TrEmbl/P) Details

Iron-sulfur cluster assembly enzyme ISCU, mitochondrial

Q6ZMB5

Interaction Score

0.56

Q6NTA2

(UniProtKB/TrEmbl/P) Details

HNRNPL protein

Q6ZMB5

Interaction Score

0.56

B3KQ30

(UniProtKB/TrEmbl/P) Details

Iron-sulfur cluster assembly enzyme ISCU, mitochondrial

Q6ZMB5

Interaction Score

0.56

E9PL69

(UniProtKB/TrEmbl/P) Details

Ribonucleoside-diphosphate reductase large subunit

Q6ZMB5

Interaction Score

0.56

P22033

(UniProtKB/Swiss-Prot/P) Details

Methylmalonyl-CoA mutase, mitochondrial

Q6ZMB5

Interaction Score

0.49

Q5BJF5

(UniProtKB/TrEmbl/P) Details

Serine hydroxymethyltransferase

Q6ZMB5

Interaction Score

0.49

Q5T6L4

(UniProtKB/TrEmbl/P) Details

Argininosuccinate synthase 1 isoform 1

Q6ZMB5

Interaction Score

0.4

Q16854

(UniProtKB/Swiss-Prot/P) Details

Deoxyguanosine kinase, mitochondrial

Q6ZMB5

Interaction Score

P23368

(UniProtKB/Swiss-Prot/P) Details

NAD-dependent malic enzyme, mitochondrial

Q6ZMB5

Interaction Score

Q9P2J9

(UniProtKB/Swiss-Prot/P) Details

[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial

Q6ZMB5

Interaction Score

Q6UUU9

(UniProtKB/TrEmbl/P) Details

Nardilysin isoform

Q6ZMB5

Interaction Score

Q5HYG8

(UniProtKB/TrEmbl/P) Details

Serine hydroxymethyltransferase

Q6ZMB5

Interaction Score

P30038

(UniProtKB/Swiss-Prot/P) Details

Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial

Q6ZMB5

Interaction Score

Q5T440

(UniProtKB/Swiss-Prot/P) Details

Putative transferase CAF17, mitochondrial

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Q6ZMB5

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

Q6ZMB5

Q03135

Caveolin-1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q6ZMB5

P55196

Afadin

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q6ZMB5

Q9UHR4

Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q6ZMB5

J3KN01

Afadin

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q6ZMB5

A8MQ02

Afadin

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q6ZMB5

Q6P996

Pyridoxal-dependent decarboxylase domain-containing protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q6ZMB5

Q9BTE3

Mini-chromosome maintenance complex-binding protein

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q6ZMB5

P14866

Heterogeneous nuclear ribonucleoprotein L

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q6ZMB5

Q96N66

Lysophospholipid acyltransferase 7

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q6ZMB5

P34897

Serine hydroxymethyltransferase, mitochondrial

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q6ZMB5

P00966

Argininosuccinate synthase

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q6ZMB5

Q96SI1

BTB/POZ domain-containing protein KCTD15

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q6ZMB5