Q6ZVZ8

Ankyrin repeat and SOCS box protein 18 // UniProt Profile

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Species	H. sapiens
Number of Interactions	33 / 42
Average Interaction Score	0.833

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Ubiquitin ligase complex (GO:0000151)	0.981	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.981	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.981	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.981	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.973	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.973	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.973	Predicted: pTarget method	LOCATE	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

Q6ZVZ8

Interaction Score

0.999

P15531

(UniProtKB/Swiss-Prot/P) Details

Nucleoside diphosphate kinase A

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.994	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.994	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.994	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.994	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Ruffle membrane (GO:0032587)	0.86	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.86	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q6ZVZ8

Interaction Score

0.999

Q15370

(UniProtKB/Swiss-Prot/P) Details

Elongin-B

Q6ZVZ8

Interaction Score

0.998

P15121

(UniProtKB/Swiss-Prot/P) Details

Aldose reductase

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Schmidt-Lanterman incisure (GO:0043220)	0.952	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.996	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Mast cell granule (GO:0042629)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Schwann cell microvillus (GO:0097454)	0.952	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Cell projection cytoplasm (GO:0032838)	0.952	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular space (GO:0005615)	0.3	Unknown: traceable author statement	GO	PubMed
Membrane	Membrane (GO:0016020)	0.952	Experimental: experimental	MatrixDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.996	Unknown: HDA	GO	PubMed
Membrane	Paranodal junction (GO:0033010)	0.952	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q6ZVZ8

Interaction Score

0.998

Q13268

(UniProtKB/Swiss-Prot/P) Details

Dehydrogenase/reductase SDR family member 2, mitochondrial

Q6ZVZ8

Interaction Score

0.996

P00966

(UniProtKB/Swiss-Prot/P) Details

Argininosuccinate synthase

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Myelin sheath (GO:0043209)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Perikaryon (GO:0043204)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial outer membrane (GO:0005741)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.86	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Lysosome (GO:0005764)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Cell body fiber (GO:0070852)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.997	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q6ZVZ8

Interaction Score

0.996

Q9NYF8

(UniProtKB/Swiss-Prot/P) Details

Bcl-2-associated transcription factor 1

Q6ZVZ8

Interaction Score

0.996

Q92734

(UniProtKB/Swiss-Prot/P) Details

Protein TFG

Q6ZVZ8

Interaction Score

0.994

O14639

(UniProtKB/Swiss-Prot/P) Details

Actin-binding LIM protein 1

Q6ZVZ8

Interaction Score

0.993

P84090

(UniProtKB/Swiss-Prot/P) Details

Enhancer of rudimentary homolog

Q6ZVZ8

Interaction Score

0.993

Q93034

(UniProtKB/Swiss-Prot/P) Details

Cullin-5

Q6ZVZ8

Interaction Score

0.986

Q13509

(UniProtKB/Swiss-Prot/P) Details

Tubulin beta-3 chain

Q6ZVZ8

Interaction Score

0.981

P05141

(UniProtKB/Swiss-Prot/P) Details

ADP/ATP translocase 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Myelin sheath (GO:0043209)	0.986	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.992	Experimental: experimental	Human Proteinpedia	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial nucleoid (GO:0042645)	0.999	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	0.999	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.3	Unknown: HDA	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.992	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	MMXD complex (GO:0071817)	0.992	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.96	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.96	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.986	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.986	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Membrane raft (GO:0045121)	0.986	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.986	Experimental: experimental	Organelle	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	0.986	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q6ZVZ8

Interaction Score

0.981

Q9Y2W1

(UniProtKB/Swiss-Prot/P) Details

Thyroid hormone receptor-associated protein 3

Q6ZVZ8

Interaction Score

0.978

Q15369

(UniProtKB/Swiss-Prot/P) Details

Elongin-C

Q6ZVZ8

Interaction Score

0.977

P60891

(UniProtKB/Swiss-Prot/P) Details

Ribose-phosphate pyrophosphokinase 1

Q6ZVZ8

Interaction Score

0.973

P23246

(UniProtKB/Swiss-Prot/P) Details

Splicing factor, proline- and glutamine-rich

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nuclear matrix (GO:0016363)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Paraspeckles (GO:0042382)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	RNA polymerase II transcription factor complex (GO:0090575)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Chromatin (GO:0000785)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Dendrite cytoplasm (GO:0032839)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q6ZVZ8

Interaction Score

0.973

Q15233

(UniProtKB/Swiss-Prot/P) Details

Non-POU domain-containing octamer-binding protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nuclear matrix (GO:0016363)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Paraspeckles (GO:0042382)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	RNA polymerase II transcription factor complex (GO:0090575)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q6ZVZ8

Interaction Score

0.972

P78332

(UniProtKB/Swiss-Prot/P) Details

RNA-binding protein 6

Q6ZVZ8

Interaction Score

0.971

Q13247

(UniProtKB/Swiss-Prot/P) Details

Serine/arginine-rich splicing factor 6

Q6ZVZ8

Interaction Score

0.963

Q14558

(UniProtKB/Swiss-Prot/P) Details

Phosphoribosyl pyrophosphate synthase-associated protein 1

Q6ZVZ8

Interaction Score

0.959

P12236

(UniProtKB/Swiss-Prot/P) Details

ADP/ATP translocase 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	0.999	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrial inner membrane presequence translocase complex (GO:0005744)	0.999	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.3	Unknown: HDA	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.96	Experimental: experimental	Human Proteinpedia	PubMed
Extracellular	Extracellular region (GO:0005576)	0.96	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.96	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.91	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Organelle inner membrane (GO:0019866)	0.96	Experimental: experimental	Organelle	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q6ZVZ8

Interaction Score

0.922

B4DP31

(UniProtKB/TrEmbl/P) Details

Phosphoribosyl pyrophosphate synthase-associated protein 1

Q6ZVZ8

Interaction Score

0.922

B7ZB02

(UniProtKB/TrEmbl/P) Details

Ribose-phosphate pyrophosphokinase 1

Q6ZVZ8

Interaction Score

0.915

Q86VG2

(UniProtKB/TrEmbl/P) Details

Splicing factor proline/glutamine-rich

Q6ZVZ8

Interaction Score

0.82

P61313

(UniProtKB/Swiss-Prot/P) Details

60S ribosomal protein L15

Q6ZVZ8

Interaction Score

0.778

E9PK91

(UniProtKB/TrEmbl/P) Details

Bcl-2-associated transcription factor 1

Q6ZVZ8

Interaction Score

0.778

E9PGM9

(UniProtKB/TrEmbl/P) Details

RNA-binding protein 6

Q6ZVZ8

Interaction Score

0.687

Q53G92

(UniProtKB/TrEmbl/P) Details

Tubulin beta chain

Q6ZVZ8

Interaction Score

0.687

Q5T6L4

(UniProtKB/TrEmbl/P) Details

Argininosuccinate synthase 1 isoform 1

Q6ZVZ8

Interaction Score

0.294

Q01726

(UniProtKB/Swiss-Prot/P) Details

Melanocyte-stimulating hormone receptor

Q6ZVZ8

Interaction Score

Q6I9V5

(UniProtKB/TrEmbl/P) Details

SLC25A6 protein

Q6ZVZ8

Interaction Score

Q6NVC0

(UniProtKB/TrEmbl/P) Details

SLC25A5 protein

Q6ZVZ8

Interaction Score

Q96HS1

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein phosphatase PGAM5, mitochondrial

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Q6ZVZ8

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

Q6ZVZ8

P15531

Nucleoside diphosphate kinase A

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q6ZVZ8

Q15370

Elongin-B

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q6ZVZ8

P15121

Aldose reductase

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q6ZVZ8

Q13268

Dehydrogenase/reductase SDR family member 2, mitochondrial

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q6ZVZ8

P00966

Argininosuccinate synthase

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q6ZVZ8

Q9NYF8

Bcl-2-associated transcription factor 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q6ZVZ8

Q92734

Protein TFG

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q6ZVZ8

O14639

Actin-binding LIM protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q6ZVZ8

P84090

Enhancer of rudimentary homolog

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q6ZVZ8

Q93034

Cullin-5

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q6ZVZ8

Q13509

Tubulin beta-3 chain

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q6ZVZ8

P05141

ADP/ATP translocase 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q6ZVZ8