Q7Z6M1

Rab9 effector protein with kelch motifs    //   UniProt Profile 

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Species

 H. sapiens

Number of Interactions

 12 / 16

Average Interaction Score

 0.966

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.937 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.937 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.937 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Trans-Golgi network membrane (GO:0032588) 0.76 Unknown: traceable author statement GO PubMed 
Secretory-pathway Endosome (GO:0005768) 0.76 Unknown: traceable author statement GO PubMed 
Secretory-pathway Endosome membrane (GO:0010008) 0.76 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Transport vesicle (GO:0030133) 0.76 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.3 Unknown: unspecified method The Human Protein Atlas PubMed 

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

Q7Z6M1

Interaction Score
0.998

Q9UJY5

(UniProtKB/Swiss-Prot/P) Details

ADP-ribosylation factor-binding protein GGA1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.96 Experimental: inferred from direct assay GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.999 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.999 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.999 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Macromolecular complex (GO:0032991) 0.999 Experimental: inferred from mutant phenotype GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.999 Experimental: experimental eSLDB PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.999 Unknown: traceable author statement GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.999 Predicted: pTarget method LOCATE PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.999 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Endosome (GO:0005768) 0.999 Experimental: experimental eSLDB PubMed 
Secretory-pathway Early endosome membrane (GO:0031901) 0.999 Unknown: traceable author statement GO PubMed 
Secretory-pathway Endosome membrane (GO:0010008) 0.999 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.902 Experimental: experimental eSLDB PubMed 
Membrane Membrane (GO:0016020) 0.902 Unknown: HDA GO PubMed 
Membrane Clathrin adaptor complex (GO:0030131) 0.902 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q7Z6M1

Interaction Score
0.998

P16435

(UniProtKB/Swiss-Prot/P) Details

NADPH--cytochrome P450 reductase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.992 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.992 Experimental: inferred from direct assay GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.992 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.987 Predicted: pTarget method LOCATE PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.987 Experimental: experimental Organelle PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.987 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 0.987 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.853 Unknown: HDA GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.853 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.853 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed 

Q7Z6M1

Interaction Score
0.997

Q9Y2I7

(UniProtKB/Swiss-Prot/P) Details

1-phosphatidylinositol 3-phosphate 5-kinase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.969 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytoplasm (GO:0005737) 0.969 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.969 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 0.969 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.79 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nuclear speck (GO:0016607) 0.79 Unknown: unspecified method The Human Protein Atlas PubMed 
Secretory-pathway Golgi membrane (GO:0000139) 0.98 Unknown: traceable author statement GO PubMed 
Secretory-pathway Late endosome membrane (GO:0031902) 0.98 Unknown: traceable author statement GO PubMed 
Secretory-pathway Early endosome membrane (GO:0031901) 0.98 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endosome membrane (GO:0010008) 0.98 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane raft (GO:0045121) 0.86 Experimental: inferred from direct assay GO PubMed 
Cytosol Vesicle membrane (GO:0012506) 0.969 Unknown: inferred from electronic annotation GO PubMed 
Membrane Cell-cell junction (GO:0005911) 0.86 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

HPRD, BioGRID

Interaction Source Publication:

PubMed 

Q7Z6M1

Interaction Score
0.996

P51151

(UniProtKB/Swiss-Prot/P) Details

Ras-related protein Rab-9A

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.986 Experimental: experimental eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.986 Unknown: traceable author statement GO PubMed 
Cytosol Cytosol (GO:0005829) 0.986 Unknown: unspecified method The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.3 Unknown: unspecified method The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.999 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Trans-Golgi network membrane (GO:0032588) 0.999 Unknown: traceable author statement GO PubMed 
Secretory-pathway Late endosome (GO:0005770) 0.999 Experimental: inferred from direct assay GO PubMed 
Cytosol Lysosome (GO:0005764) 0.986 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Phagocytic vesicle (GO:0045335) 0.999 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Phagocytic vesicle membrane (GO:0030670) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Melanosome (GO:0042470) 0.999 Predicted: inferred from sequence or structural similarity GO PubMed 
Secretory-pathway Transport vesicle (GO:0030133) 0.999 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.958 Experimental: experimental eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.958 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.958 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.986 Unknown: HDA GO PubMed 

Interaction Source Database:

HPRD, BioGRID

Interaction Source Publication:

PubMed 

Q7Z6M1

Interaction Score
0.994

O75569

(UniProtKB/Swiss-Prot/P) Details

Interferon-inducible double-stranded RNA-dependent protein kinase activator A

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: pTarget method LOCATE PubMed 
Cytosol RISC-loading complex (GO:0070578) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 1 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.988 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.988 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.988 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.3 Unknown: HDA GO PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed 

Q7Z6M1

Interaction Score
0.989

Q15942

(UniProtKB/Swiss-Prot/P) Details

Zyxin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.96 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.96 Experimental: experimental Human Proteinpedia PubMed 
Secretory-pathway Phagocytic vesicle (GO:0045335) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Experimental: experimental eSLDB PubMed 
Cytosol Stress fiber (GO:0001725) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.998 Experimental: experimental Organelle PubMed 
Membrane Focal adhesion (GO:0005925) 0.998 Experimental: inferred from direct assay GO PubMed 
Membrane Focal adhesion (GO:0005925) 0.998 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Cell-cell adherens junction (GO:0005913) 0.998 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed 

Q7Z6M1

Interaction Score
0.98

Q9Y6A4

(UniProtKB/Swiss-Prot/P) Details

Cilia- and flagella-associated protein 20

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.96 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Cilium basal body (GO:0036064) 0.98 Experimental: inferred from direct assay GO PubMed 
Cytosol Centriole (GO:0005814) 0.98 Experimental: inferred from direct assay GO PubMed 
Cytosol Microtubule (GO:0005874) 0.98 Unknown: inferred from electronic annotation GO PubMed 
Membrane Cilium (GO:0005929) 0.8 Experimental: inferred from direct assay GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.98 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q7Z6M1

Interaction Score
0.974

P15104

(UniProtKB/Swiss-Prot/P) Details

Glutamine synthetase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Myelin sheath (GO:0043209) 0.657 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Perikaryon (GO:0043204) 0.998 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.998 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.998 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.998 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.998 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.96 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.51 Unknown: HDA GO PubMed 
Nucleus Macromolecular complex (GO:0032991) 0.51 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Rough endoplasmic reticulum (GO:0005791) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Membrane Glial cell projection (GO:0097386) 0.657 Unknown: inferred from electronic annotation GO PubMed 
Membrane Nerve terminal (GO:0043679) 0.657 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.998 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

Q7Z6M1

Interaction Score
0.964

Q9Y2Y6

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 98

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.988 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.988 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.988 Experimental: experimental Human Proteinpedia PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.3 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

Q7Z6M1

Interaction Score
0.937

Q8IVT2

(UniProtKB/Swiss-Prot/P) Details

Mitotic interactor and substrate of PLK1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.971 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cell cortex (GO:0005938) 0.971 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.971 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 0.971 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.998 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.998 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Focal adhesion (GO:0005925) 0.998 Experimental: inferred from direct assay GO PubMed 
Membrane Focal adhesion (GO:0005925) 0.998 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q7Z6M1

Interaction Score
0.882

Q9UF02

(UniProtKB/Swiss-Prot/P) Details

Voltage-dependent calcium channel gamma-5 subunit

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Postsynaptic density (GO:0014069) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Experimental: experimental eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 1 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: pTarget method LOCATE PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex (GO:0032281) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Cell junction (GO:0030054) 1 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q7Z6M1

Interaction Score
0.881

O43688

(UniProtKB/Swiss-Prot/P) Details

Phospholipid phosphatase 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Mitochondrion Mitochondrion (GO:0005739) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.987 Unknown: traceable author statement GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.987 Predicted: SVM decision tree eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.987 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.987 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.987 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

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ComPPI is published in Nucleic Acids Research Database Issue 2015