Q86UN6

A-kinase anchor protein 14 // UniProt Profile

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Species	H. sapiens
Number of Interactions	20 / 32
Average Interaction Score	0.757

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	CAMP-dependent protein kinase complex (GO:0005952)	0.996	Experimental: inferred from mutant phenotype	GO	PubMed
Cytosol	Axoneme (GO:0005930)	0.996	Experimental: inferred from direct assay	GO	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

Q86UN6

Interaction Score

0.996

P17612

(UniProtKB/Swiss-Prot/P) Details

cAMP-dependent protein kinase catalytic subunit alpha

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	CAMP-dependent protein kinase complex (GO:0005952)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.972	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.972	Unknown: traceable author statement	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.972	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Acrosomal vesicle (GO:0001669)	0.7	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Axoneme (GO:0005930)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Ciliary base (GO:0097546)	0.931	Unknown: traceable author statement	GO	PubMed
Membrane	Motile cilium (GO:0031514)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.96	Experimental: experimental	MatrixDB	PubMed
Extracellular	Intercellular bridge (GO:0045171)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Membrane (GO:0016020)	0.931	Experimental: inferred from direct assay	GO	PubMed
Membrane	Calcium channel complex (GO:0034704)	0.931	Unknown: traceable author statement	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, HPRD

Interaction Source Publication:

PubMed

, PubMed

Q86UN6

Interaction Score

0.996

P13861

(UniProtKB/Swiss-Prot/P) Details

cAMP-dependent protein kinase type II-alpha regulatory subunit

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	CAMP-dependent protein kinase complex (GO:0005952)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	AMP-activated protein kinase complex (GO:0031588)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.8	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Axoneme (GO:0005930)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Ciliary base (GO:0097546)	0.986	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.986	Unknown: HDA	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.986	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.986	Experimental: experimental	Organelle	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.986	Unknown: HDA	GO	PubMed

Interaction Source Database:

HPRD, BioGRID

Interaction Source Publication:

PubMed

Q86UN6

Interaction Score

0.996

P31323

(UniProtKB/Swiss-Prot/P) Details

cAMP-dependent protein kinase type II-beta regulatory subunit

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Neuronal cell body (GO:0043025)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	CAMP-dependent protein kinase complex (GO:0005952)	1	Unknown: inferred from electronic annotation	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.86	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Dendritic shaft (GO:0043198)	0.991	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Dendritic spine (GO:0043197)	0.991	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Ciliary base (GO:0097546)	0.991	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane raft (GO:0045121)	0.991	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.991	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed

, PubMed

Q86UN6

Interaction Score

0.996

P22694

(UniProtKB/Swiss-Prot/P) Details

cAMP-dependent protein kinase catalytic subunit beta

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	CAMP-dependent protein kinase complex (GO:0005952)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.3	Unknown: traceable author statement	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Ciliary base (GO:0097546)	0.51	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.96	Experimental: experimental	MatrixDB	PubMed
Extracellular	Intercellular bridge (GO:0045171)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q86UN6

Interaction Score

0.993

Q15506

(UniProtKB/Swiss-Prot/P) Details

Sperm surface protein Sp17

Q86UN6

Interaction Score

0.993

P22612

(UniProtKB/Swiss-Prot/P) Details

cAMP-dependent protein kinase catalytic subunit gamma

Q86UN6

Interaction Score

0.983

P31321

(UniProtKB/Swiss-Prot/P) Details

cAMP-dependent protein kinase type I-beta regulatory subunit

Q86UN6

Interaction Score

0.978

A8K855

(UniProtKB/Swiss-Prot/P) Details

EF-hand calcium-binding domain-containing protein 7

Q86UN6

Interaction Score

0.957

Q99417

(UniProtKB/Swiss-Prot/P) Details

c-Myc-binding protein

Q86UN6

Interaction Score

0.937

B1APG3

(UniProtKB/TrEmbl/P) Details

cAMP-dependent protein kinase catalytic subunit beta

Q86UN6

Interaction Score

0.937

B1APF9

(UniProtKB/TrEmbl/P) Details

cAMP-dependent protein kinase catalytic subunit beta

Q86UN6

Interaction Score

0.937

Q9HAT0

(UniProtKB/Swiss-Prot/P) Details

Ropporin-1A

Q86UN6

Interaction Score

0.857

P13637

(UniProtKB/Swiss-Prot/P) Details

Sodium/potassium-transporting ATPase subunit alpha-3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Neuronal cell body (GO:0043025)	0.86	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Neuronal cell body membrane (GO:0032809)	0.86	Unknown: inferred by curator	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.96	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Axon (GO:0030424)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Unknown: non-traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Sodium:potassium-exchanging ATPase complex (GO:0005890)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Synapse (GO:0045202)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q86UN6

Interaction Score

0.797

A0A087WVC4

(UniProtKB/TrEmbl/P) Details

cAMP-dependent protein kinase catalytic subunit beta

Q86UN6

Interaction Score

0.797

B3KY43

(UniProtKB/TrEmbl/P) Details

cDNA FLJ46798 fis, clone TRACH3031660, highly similar to cAMP-dependent protein kinase type II-beta regulatory subunit

Q86UN6

Interaction Score

0.697

Q9C005

(UniProtKB/Swiss-Prot/P) Details

Protein dpy-30 homolog

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Histone methyltransferase complex (GO:0035097)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	MLL3/4 complex (GO:0044666)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Set1C/COMPASS complex (GO:0048188)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.992	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Trans-Golgi network (GO:0005802)	0.992	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Chromosome, telomeric region (GO:0000781)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q86UN6

Interaction Score

0.299

Q96KC2

(UniProtKB/Swiss-Prot/P) Details

ADP-ribosylation factor-like protein 5B

Q86UN6

Interaction Score

Q53ES0

(UniProtKB/TrEmbl/P) Details

Sodium/potassium-transporting ATPase subunit alpha

Q86UN6

Interaction Score

P57105

(UniProtKB/Swiss-Prot/P) Details

Synaptojanin-2-binding protein

Q86UN6

Interaction Score

Q9NX40

(UniProtKB/Swiss-Prot/P) Details

OCIA domain-containing protein 1

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Q86UN6

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

Q86UN6

P17612

cAMP-dependent protein kinase catalytic subunit alpha

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86UN6

P13861

cAMP-dependent protein kinase type II-alpha regulatory subunit

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86UN6

P31323

cAMP-dependent protein kinase type II-beta regulatory subunit

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86UN6

P22694

cAMP-dependent protein kinase catalytic subunit beta

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86UN6

Q15506

Sperm surface protein Sp17

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86UN6

P22612

cAMP-dependent protein kinase catalytic subunit gamma

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86UN6

P31321

cAMP-dependent protein kinase type I-beta regulatory subunit

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86UN6

A8K855

EF-hand calcium-binding domain-containing protein 7

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86UN6

Q99417

c-Myc-binding protein

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86UN6

B1APG3

cAMP-dependent protein kinase catalytic subunit beta

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86UN6

B1APF9

cAMP-dependent protein kinase catalytic subunit beta

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86UN6

Q9HAT0

Ropporin-1A

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86UN6