Q86VG3

Uncharacterized protein C11orf74 // UniProt Profile

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Species	H. sapiens
Number of Interactions	12 / 19
Average Interaction Score	0.767

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Aggresome (GO:0016235)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytosol (GO:0005829)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Cilium (GO:0005929)	0.3	Unknown: inferred from electronic annotation	GO	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

Q86VG3

Interaction Score

0.997

P53350

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein kinase PLK1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Midbody (GO:0030496)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Spindle (GO:0005819)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Spindle midzone (GO:0051233)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Spindle microtubule (GO:0005876)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Spindle pole (GO:0000922)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Centriolar satellite (GO:0034451)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Centriole (GO:0005814)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Condensed nuclear chromosome outer kinetochore (GO:0000942)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Synaptonemal complex (GO:0000795)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Chromatin (GO:0000785)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Kinetochore (GO:0000776)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q86VG3

Interaction Score

0.997

Q96FT9

(UniProtKB/Swiss-Prot/P) Details

Intraflagellar transport protein 43 homolog

Q86VG3

Interaction Score

0.997

Q9P2L0

(UniProtKB/Swiss-Prot/P) Details

WD repeat-containing protein 35

Q86VG3

Interaction Score

0.997

Q9HBG6

(UniProtKB/Swiss-Prot/P) Details

Intraflagellar transport protein 122 homolog

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cilium basal body (GO:0036064)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Intraflagellar transport particle A (GO:0030991)	0.999	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cilium (GO:0005929)	0.956	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Ciliary base (GO:0097546)	0.956	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Photoreceptor connecting cilium (GO:0032391)	0.956	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.956	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q86VG3

Interaction Score

0.997

Q96RY7

(UniProtKB/Swiss-Prot/P) Details

Intraflagellar transport protein 140 homolog

Q86VG3

Interaction Score

0.997

Q9Y4C4

(UniProtKB/Swiss-Prot/P) Details

Malignant fibrous histiocytoma-amplified sequence 1

Q86VG3

Interaction Score

0.996

P36873

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Midbody (GO:0030496)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Protein phosphatase type 1 complex (GO:0000164)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	PTW/PP1 phosphatase complex (GO:0072357)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cleavage furrow (GO:0032154)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.86	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial outer membrane (GO:0005741)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.999	Experimental: inferred from mutant phenotype	GO	PubMed
Nucleus	Nuclear chromosome, telomeric region (GO:0000784)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Condensed chromosome kinetochore (GO:0000777)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendritic spine (GO:0043197)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.657	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

Q86VG3

Interaction Score

0.977

Q8NEZ3

(UniProtKB/Swiss-Prot/P) Details

WD repeat-containing protein 19

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.971	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.971	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.971	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Intraflagellar transport particle A (GO:0030991)	0.971	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cilium (GO:0005929)	0.981	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Motile cilium (GO:0031514)	0.981	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Photoreceptor connecting cilium (GO:0032391)	0.981	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Photoreceptor outer segment (GO:0001750)	0.981	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q86VG3

Interaction Score

0.95

Q16763

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin-conjugating enzyme E2 S

Q86VG3

Interaction Score

0.3

Q14973

(UniProtKB/Swiss-Prot/P) Details

Sodium/bile acid cotransporter

Q86VG3

Interaction Score

Q8TAQ2

(UniProtKB/Swiss-Prot/P) Details

SWI/SNF complex subunit SMARCC2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Transcriptional repressor complex (GO:0017053)	1	Predicted: inferred from physical interaction	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Unknown: HDA	GO	PubMed
Nucleus	SWI/SNF complex (GO:0016514)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	NBAF complex (GO:0071565)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	NpBAF complex (GO:0071564)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nuclear chromatin (GO:0000790)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

Q86VG3

Interaction Score

F8VXC8

(UniProtKB/TrEmbl/P) Details

SWI/SNF complex subunit SMARCC2

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Q86VG3

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

Q86VG3

P53350

Serine/threonine-protein kinase PLK1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86VG3

Q96FT9

Intraflagellar transport protein 43 homolog

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86VG3

Q9P2L0

WD repeat-containing protein 35

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86VG3

Q9HBG6

Intraflagellar transport protein 122 homolog

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86VG3

Q96RY7

Intraflagellar transport protein 140 homolog

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86VG3

Q9Y4C4

Malignant fibrous histiocytoma-amplified sequence 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86VG3

P36873

Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86VG3

Q8NEZ3

WD repeat-containing protein 19

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86VG3

Q16763

Ubiquitin-conjugating enzyme E2 S

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86VG3

Q14973

Sodium/bile acid cotransporter

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86VG3

Q8TAQ2

SWI/SNF complex subunit SMARCC2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86VG3

F8VXC8

SWI/SNF complex subunit SMARCC2

Localizations:

Interaction Source Database:

Interaction Source Publication: