Q86Y78

Ly6/PLAUR domain-containing protein 6 // UniProt Profile

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Species	H. sapiens
Number of Interactions	46 / 54
Average Interaction Score	0.931

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.8	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.86	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Neuron projection (GO:0043005)	0.976	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.958	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.958	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.958	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Membrane (GO:0016020)	0.976	Experimental: experimental	MatrixDB	PubMed
Membrane	Anchored to membrane (GO:0031225)	0.976	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Membrane raft (GO:0045121)	0.976	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.976	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.976	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Synapse (GO:0045202)	0.976	Unknown: inferred from electronic annotation	GO	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

Q86Y78

Interaction Score

P50570

(UniProtKB/Swiss-Prot/P) Details

Dynamin-2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Midbody (GO:0030496)	0.995	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Photoreceptor inner segment (GO:0001917)	0.995	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Coated pit (GO:0005905)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Unknown: inferred from electronic annotation	GO	PubMed
Mitochondrion	Mitochondrial membrane (GO:0031966)	0.7	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.853	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.853	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.853	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.995	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.995	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.995	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Trans-Golgi network (GO:0005802)	0.995	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.995	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endocytic vesicle membrane (GO:0030666)	0.995	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Phagocytic vesicle membrane (GO:0030670)	0.995	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Clathrin-coated endocytic vesicle (GO:0045334)	0.995	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Microtubule (GO:0005874)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Growth cone (GO:0030426)	0.995	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Ruffle membrane (GO:0032587)	0.995	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Lamellipodium (GO:0030027)	0.995	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.995	Unknown: traceable author statement	GO	PubMed
Membrane	Phagocytic cup (GO:0001891)	0.995	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.995	Unknown: HDA	GO	PubMed
Membrane	Postsynaptic membrane (GO:0045211)	0.995	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q86Y78

Interaction Score

P13637

(UniProtKB/Swiss-Prot/P) Details

Sodium/potassium-transporting ATPase subunit alpha-3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Neuronal cell body (GO:0043025)	0.86	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Neuronal cell body membrane (GO:0032809)	0.86	Unknown: inferred by curator	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.96	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Axon (GO:0030424)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Unknown: non-traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Sodium:potassium-exchanging ATPase complex (GO:0005890)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Synapse (GO:0045202)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q86Y78

Interaction Score

0.999

P18031

(UniProtKB/Swiss-Prot/P) Details

Tyrosine-protein phosphatase non-receptor type 1

Q86Y78

Interaction Score

0.999

Q8NEW0

(UniProtKB/Swiss-Prot/P) Details

Zinc transporter 7

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.972	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.994	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.994	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.994	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.937	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.937	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.937	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Vesicle (GO:0031982)	0.972	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q86Y78

Interaction Score

0.999

Q9HCU4

(UniProtKB/Swiss-Prot/P) Details

Cadherin EGF LAG seven-pass G-type receptor 2

Q86Y78

Interaction Score

0.999

Q07065

(UniProtKB/Swiss-Prot/P) Details

Cytoskeleton-associated protein 4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Lipid particle (GO:0005811)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Unknown: unspecified method	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.958	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.958	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.958	Unknown: unspecified method	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.986	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Rough endoplasmic reticulum (GO:0005791)	0.986	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum lumen (GO:0005788)	0.986	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.986	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Lamellar body (GO:0042599)	0.986	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.96	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.96	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.657	Unknown: traceable author statement	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.657	Unknown: traceable author statement	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.999	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q86Y78

Interaction Score

0.999

Q96GX1

(UniProtKB/Swiss-Prot/P) Details

Tectonic-2

Q86Y78

Interaction Score

0.999

Q9UQ16

(UniProtKB/Swiss-Prot/P) Details

Dynamin-3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Photoreceptor inner segment (GO:0001917)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Mitochondrion	Mitochondrial membrane (GO:0031966)	0.7	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.86	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Microtubule (GO:0005874)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendritic spine (GO:0043197)	0.996	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Dendritic spine head (GO:0044327)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic density (GO:0014069)	0.996	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Axon (GO:0030424)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.996	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Synaptic cleft (GO:0043083)	0.996	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q86Y78

Interaction Score

0.999

Q14332

(UniProtKB/Swiss-Prot/P) Details

Frizzled-2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.8	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear body (GO:0016604)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Clathrin-coated endocytic vesicle membrane (GO:0030669)	0.3	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Cell junction (GO:0030054)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q86Y78

Interaction Score

0.998

Q6UWP7

(UniProtKB/Swiss-Prot/P) Details

Lysocardiolipin acyltransferase 1

Q86Y78

Interaction Score

0.998

O15031

(UniProtKB/Swiss-Prot/P) Details

Plexin-B2

Q86Y78

Interaction Score

0.998

Q92604

(UniProtKB/Swiss-Prot/P) Details

Acyl-CoA:lysophosphatidylglycerol acyltransferase 1

Q86Y78

Interaction Score

0.998

Q9UP95

(UniProtKB/Swiss-Prot/P) Details

Solute carrier family 12 member 4

Q86Y78

Interaction Score

0.998

Q6NUQ4

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 214

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytoplasmic microtubule (GO:0005881)	0.992	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.79	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q86Y78

Interaction Score

0.998

Q13433

(UniProtKB/Swiss-Prot/P) Details

Zinc transporter ZIP6

Q86Y78

Interaction Score

0.998

Q8NBJ9

(UniProtKB/Swiss-Prot/P) Details

SID1 transmembrane family member 2

Q86Y78

Interaction Score

0.998

P43681

(UniProtKB/Swiss-Prot/P) Details

Neuronal acetylcholine receptor subunit alpha-4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Neuronal cell body (GO:0043025)	0.7	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Dendrite (GO:0030425)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Unknown: non-traceable author statement	GO	PubMed
Membrane	Acetylcholine-gated channel complex (GO:0005892)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: pTarget method	LOCATE	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	External side of plasma membrane (GO:0009897)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic membrane (GO:0045211)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q86Y78

Interaction Score

0.998

P32297

(UniProtKB/Swiss-Prot/P) Details

Neuronal acetylcholine receptor subunit alpha-3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Neuronal cell body (GO:0043025)	0.7	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Dendrite (GO:0030425)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Postsynaptic density (GO:0014069)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Unknown: non-traceable author statement	GO	PubMed
Membrane	Acetylcholine-gated channel complex (GO:0005892)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: pTarget method	LOCATE	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Cell junction (GO:0030054)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic membrane (GO:0045211)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q86Y78

Interaction Score

0.998

Q9H3N1

(UniProtKB/Swiss-Prot/P) Details

Thioredoxin-related transmembrane protein 1

Q86Y78

Interaction Score

0.998

Q9NYQ6

(UniProtKB/Swiss-Prot/P) Details

Cadherin EGF LAG seven-pass G-type receptor 1

Q86Y78

Interaction Score

0.997

P35610

(UniProtKB/Swiss-Prot/P) Details

Sterol O-acyltransferase 1

Q86Y78

Interaction Score

0.996

P30926

(UniProtKB/Swiss-Prot/P) Details

Neuronal acetylcholine receptor subunit beta-4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Tertiary granule membrane (GO:0070821)	0.3	Unknown: traceable author statement	GO	PubMed
Membrane	Neuron projection (GO:0043005)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Unknown: non-traceable author statement	GO	PubMed
Membrane	Acetylcholine-gated channel complex (GO:0005892)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: pTarget method	LOCATE	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Unknown: inferred by curator	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic membrane (GO:0045211)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q86Y78

Interaction Score

0.995

Q9H330

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 245

Q86Y78

Interaction Score

0.995

P30532

(UniProtKB/Swiss-Prot/P) Details

Neuronal acetylcholine receptor subunit alpha-5

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Acetylcholine-gated channel complex (GO:0005892)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: pTarget method	LOCATE	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Cell junction (GO:0030054)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Postsynaptic membrane (GO:0045211)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q86Y78

Interaction Score

0.994

P36544

(UniProtKB/Swiss-Prot/P) Details

Neuronal acetylcholine receptor subunit alpha-7

Q86Y78

Interaction Score

0.994

P17787

(UniProtKB/Swiss-Prot/P) Details

Neuronal acetylcholine receptor subunit beta-2

Q86Y78

Interaction Score

0.994

Q15825

(UniProtKB/Swiss-Prot/P) Details

Neuronal acetylcholine receptor subunit alpha-6

Q86Y78

Interaction Score

0.992

Q9H228

(UniProtKB/Swiss-Prot/P) Details

Sphingosine 1-phosphate receptor 5

Q86Y78

Interaction Score

0.991

Q05193

(UniProtKB/Swiss-Prot/P) Details

Dynamin-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Photoreceptor inner segment (GO:0001917)	0.966	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Myelin sheath (GO:0043209)	0.966	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.853	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrial membrane (GO:0031966)	0.7	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Synaptic vesicle (GO:0008021)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Microtubule (GO:0005874)	0.853	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Varicosity (GO:0043196)	0.966	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Membrane coat (GO:0030117)	0.966	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.966	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.966	Experimental: experimental	Organelle	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.853	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q86Y78

Interaction Score

0.99

Q9GZR5

(UniProtKB/Swiss-Prot/P) Details

Elongation of very long chain fatty acids protein 4

Q86Y78

Interaction Score

0.988

Q8WVP7

(UniProtKB/Swiss-Prot/P) Details

Limb region 1 protein homolog

Q86Y78

Interaction Score

0.984

Q96FL8

(UniProtKB/Swiss-Prot/P) Details

Multidrug and toxin extrusion protein 1

Q86Y78

Interaction Score

0.983

Q96MH6

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 68

Q86Y78

Interaction Score

0.982

Q9UNW1

(UniProtKB/Swiss-Prot/P) Details

Multiple inositol polyphosphate phosphatase 1

Q86Y78

Interaction Score

0.98

Q96S06

(UniProtKB/Swiss-Prot/P) Details

Lipase maturation factor 1

Q86Y78

Interaction Score

0.977

Q96CW5

(UniProtKB/Swiss-Prot/P) Details

Gamma-tubulin complex component 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Spindle (GO:0005819)	1	Unknown: non-traceable author statement	GO	PubMed
Cytosol	Polar microtubule (GO:0005827)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Spindle pole body (GO:0005816)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Unknown: non-traceable author statement	GO	PubMed
Cytosol	Centriole (GO:0005814)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Gamma-tubulin small complex (GO:0008275)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q86Y78

Interaction Score

0.974

Q9H1A3

(UniProtKB/Swiss-Prot/P) Details

Methyltransferase-like protein 9

Q86Y78

Interaction Score

0.926

Q53ES0

(UniProtKB/TrEmbl/P) Details

Sodium/potassium-transporting ATPase subunit alpha

Q86Y78

Interaction Score

0.916

B4DSN5

(UniProtKB/TrEmbl/P) Details

Tyrosine-protein phosphatase non-receptor type

Q86Y78

Interaction Score

0.781

Q86UZ8

(UniProtKB/TrEmbl/P) Details

FZD2 protein

Q86Y78

Interaction Score

0.766

H3BVI4

(UniProtKB/TrEmbl/P) Details

Lipase maturation factor

Q86Y78

Interaction Score

0.766

A8K3M3

(UniProtKB/TrEmbl/P) Details

Tyrosine-protein phosphatase non-receptor type

Q86Y78

Interaction Score

0.688

E5RJN2

(UniProtKB/TrEmbl/P) Details

Transmembrane protein 68

Q86Y78

Interaction Score

0.602

Q9UHA2

(UniProtKB/Swiss-Prot/P) Details

SS18-like protein 2

Q86Y78

Interaction Score

0.602

Q8N1K8

(UniProtKB/TrEmbl/P) Details

cDNA FLJ40556 fis, clone THYMU2002583, highly similar to DYNAMIN 2

Q86Y78

Interaction Score

A0A0D9SFE4

(UniProtKB/TrEmbl/P) Details

Dynamin-1

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Q86Y78

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

Q86Y78

P50570

Dynamin-2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86Y78

P13637

Sodium/potassium-transporting ATPase subunit alpha-3

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86Y78

P18031

Tyrosine-protein phosphatase non-receptor type 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86Y78

Q8NEW0

Zinc transporter 7

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86Y78

Q9HCU4

Cadherin EGF LAG seven-pass G-type receptor 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86Y78

Q07065

Cytoskeleton-associated protein 4

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86Y78

Q96GX1

Tectonic-2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86Y78

Q9UQ16

Dynamin-3

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86Y78

Q14332

Frizzled-2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86Y78

Q6UWP7

Lysocardiolipin acyltransferase 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86Y78

O15031

Plexin-B2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86Y78

Q92604

Acyl-CoA:lysophosphatidylglycerol acyltransferase 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86Y78