Q8IVP5

FUN14 domain-containing protein 1 // UniProt Profile

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Species	H. sapiens
Number of Interactions	20 / 24
Average Interaction Score	0.666

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Mitochondrion	Mitochondrion (GO:0005739)	0.988	Predicted: pTarget method	LOCATE	PubMed
Mitochondrion	Mitochondrial outer membrane (GO:0005741)	0.988	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Integral to mitochondrial outer membrane (GO:0031307)	0.988	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

First-Neighbour Network Visualization

Toggle Display

The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

Q8IVP5

Interaction Score

0.998

Q96AG3

(UniProtKB/Swiss-Prot/P) Details

Solute carrier family 25 member 46

Q8IVP5

Interaction Score

0.998

P49411

(UniProtKB/Swiss-Prot/P) Details

Elongation factor Tu, mitochondrial

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Myelin sheath (GO:0043209)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.958	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial nucleoid (GO:0042645)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.958	Experimental: experimental	Human Proteinpedia	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.657	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.958	Unknown: HDA	GO	PubMed
Membrane	Synapse (GO:0045202)	0.657	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

CCSB, IntAct, BioGRID

Interaction Source Publication:

PubMed

Q8IVP5

Interaction Score

0.997

Q9NX47

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase MARCH5

Q8IVP5

Interaction Score

0.992

Q9BWH2

(UniProtKB/Swiss-Prot/P) Details

FUN14 domain-containing protein 2

Q8IVP5

Interaction Score

0.986

Q96E29

(UniProtKB/Swiss-Prot/P) Details

Transcription termination factor 3, mitochondrial

Q8IVP5

Interaction Score

0.974

Q9HC62

(UniProtKB/Swiss-Prot/P) Details

Sentrin-specific protease 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endomembrane system (GO:0012505)	0.998	Experimental: experimental	Organelle	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Pore complex (GO:0046930)	0.94	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: experimental	Organelle	PubMed
Nucleus	Nuclear membrane (GO:0031965)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nuclear pore (GO:0005643)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.999	Unknown: traceable author statement	GO	PubMed
Nucleus	PML body (GO:0016605)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

Q8IVP5

Interaction Score

0.974

Q9GZQ8

(UniProtKB/Swiss-Prot/P) Details

Microtubule-associated proteins 1A/1B light chain 3B

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endomembrane system (GO:0012505)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Intracellular (GO:0005622)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.94	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.94	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.79	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Autophagic vacuole (GO:0005776)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Autophagic vacuole membrane (GO:0000421)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.79	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Microtubule (GO:0005874)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Axoneme (GO:0005930)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Cytosol	Organelle membrane (GO:0031090)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

IntAct, BioGRID, CCSB

Interaction Source Publication:

PubMed

, PubMed

Q8IVP5

Interaction Score

0.951

Q9H0R8

(UniProtKB/Swiss-Prot/P) Details

Gamma-aminobutyric acid receptor-associated protein-like 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cell body (GO:0044297)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Intracellular (GO:0005622)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: inferred from genetic interaction	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.897	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Autophagic vacuole (GO:0005776)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Autophagic vacuole membrane (GO:0000421)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle membrane (GO:0030659)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Microtubule (GO:0005874)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendrite cytoplasm (GO:0032839)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendrite membrane (GO:0032590)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed

Q8IVP5

Interaction Score

0.917

Q9Y371

(UniProtKB/Swiss-Prot/P) Details

Endophilin-B1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Midbody (GO:0030496)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial outer membrane (GO:0005741)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Autophagic vacuole membrane (GO:0000421)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.96	Experimental: experimental	eSLDB	PubMed

Interaction Source Database:

IntAct, BioGRID, CCSB

Interaction Source Publication:

PubMed

Q8IVP5

Interaction Score

0.899

Q08426

(UniProtKB/Swiss-Prot/P) Details

Peroxisomal bifunctional enzyme

Q8IVP5

Interaction Score

0.891

P07947

(UniProtKB/Swiss-Prot/P) Details

Tyrosine-protein kinase Yes

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Actin filament (GO:0005884)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.997	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.997	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.997	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Extrinsic to internal side of plasma membrane (GO:0031234)	0.997	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.999	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.997	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct, BioGRID, CCSB

Interaction Source Publication:

PubMed

Q8IVP5

Interaction Score

0.881

Q13596

(UniProtKB/Swiss-Prot/P) Details

Sorting nexin-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Retromer complex (GO:0030904)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Retromer complex, outer shell (GO:0030905)	1	Predicted: inferred from physical interaction	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.8	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Early endosome membrane (GO:0031901)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endosome membrane (GO:0010008)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Lysosome (GO:0005764)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Lysosome (GO:0005764)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Lamellipodium (GO:0030027)	0.958	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.958	Experimental: inferred from direct assay	GO	PubMed
Membrane	Extrinsic to membrane (GO:0019898)	0.958	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Vesicle (GO:0031982)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

Q8IVP5

Interaction Score

0.857

Q9H492

(UniProtKB/Swiss-Prot/P) Details

Microtubule-associated proteins 1A/1B light chain 3A

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.79	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Late endosome (GO:0005770)	0.79	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Autophagic vacuole (GO:0005776)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Autophagic vacuole membrane (GO:0000421)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Microtubule (GO:0005874)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.86	Experimental: experimental	eSLDB	PubMed
Cytosol	Organelle membrane (GO:0031090)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Synapse (GO:0045202)	0.86	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

Q8IVP5

Interaction Score

0.79

E5RIK9

(UniProtKB/TrEmbl/P) Details

Transcription termination factor 3, mitochondrial

Q8IVP5

Interaction Score

0.21

P56545

(UniProtKB/Swiss-Prot/P) Details

C-terminal-binding protein 2

Q8IVP5

Interaction Score

Q5SQP8

(UniProtKB/TrEmbl/P) Details

C-terminal-binding protein 2

Q8IVP5

Interaction Score

P60520

(UniProtKB/Swiss-Prot/P) Details

Gamma-aminobutyric acid receptor-associated protein-like 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular (GO:0005622)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.999	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.999	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Autophagic vacuole (GO:0005776)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Autophagic vacuole membrane (GO:0000421)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.999	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

CCSB, IntAct, BioGRID

Interaction Source Publication:

PubMed

Q8IVP5

Interaction Score

Q13363

(UniProtKB/Swiss-Prot/P) Details

C-terminal-binding protein 1

Q8IVP5

Interaction Score

Q658J6

(UniProtKB/TrEmbl/P) Details

Microtubule-associated protein 1 light chain 3 beta, isoform CRA_c

Q8IVP5

Interaction Score

A0A087WW40

(UniProtKB/TrEmbl/P) Details

Endophilin-B1

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Q8IVP5

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

Q8IVP5

Q96AG3

Solute carrier family 25 member 46

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q8IVP5

P49411

Elongation factor Tu, mitochondrial

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q8IVP5

Q9NX47

E3 ubiquitin-protein ligase MARCH5

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q8IVP5

Q9BWH2

FUN14 domain-containing protein 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q8IVP5

Q96E29

Transcription termination factor 3, mitochondrial

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q8IVP5

Q9HC62

Sentrin-specific protease 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q8IVP5

Q9GZQ8

Microtubule-associated proteins 1A/1B light chain 3B

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q8IVP5

Q9H0R8

Gamma-aminobutyric acid receptor-associated protein-like 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q8IVP5

Q9Y371

Endophilin-B1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q8IVP5

Q08426

Peroxisomal bifunctional enzyme

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q8IVP5

P07947

Tyrosine-protein kinase Yes

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q8IVP5

Q13596

Sorting nexin-1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q8IVP5