Q8N3Y7

Epidermal retinol dehydrogenase 2    //   UniProt Profile 

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Species

 H. sapiens

Number of Interactions

 13 / 15

Average Interaction Score

 0.786

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.996 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Experimental: inferred from direct assay GO PubMed 
Nucleus Transcriptional repressor complex (GO:0017053) 0.992 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.996 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.996 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 0.996 Experimental: inferred from direct assay GO PubMed 
Nucleus Chromatin (GO:0000785) 0.992 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.86 Experimental: inferred from direct assay GO PubMed 

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

Q8N3Y7

Interaction Score
1

Q13596

(UniProtKB/Swiss-Prot/P) Details

Sorting nexin-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Retromer complex (GO:0030904) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Retromer complex, outer shell (GO:0030905) 1 Predicted: inferred from physical interaction GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Macromolecular complex (GO:0032991) 0.8 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Endosome (GO:0005768) 0.999 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endosome (GO:0005768) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Early endosome membrane (GO:0031901) 0.999 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endosome membrane (GO:0010008) 0.999 Experimental: inferred from direct assay GO PubMed 
Cytosol Lysosome (GO:0005764) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Lysosome (GO:0005764) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Lamellipodium (GO:0030027) 0.958 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.958 Experimental: inferred from direct assay GO PubMed 
Membrane Extrinsic to membrane (GO:0019898) 0.958 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Vesicle (GO:0031982) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q8N3Y7

Interaction Score
0.999

Q92935

(UniProtKB/Swiss-Prot/P) Details

Exostosin-like 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.996 Experimental: experimental eSLDB PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.996 Predicted: pTarget method LOCATE PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.996 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 0.996 Unknown: traceable author statement GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.996 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.86 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.86 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

Q8N3Y7

Interaction Score
0.998

Q9HC62

(UniProtKB/Swiss-Prot/P) Details

Sentrin-specific protease 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Endomembrane system (GO:0012505) 0.998 Experimental: experimental Organelle PubMed 
Cytosol Cytoplasm (GO:0005737) 0.998 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.998 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.998 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.94 Predicted: SVM decision tree eSLDB PubMed 
Mitochondrion Pore complex (GO:0046930) 0.94 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 0.999 Experimental: experimental Human Proteinpedia PubMed 
Nucleus Nucleus (GO:0005634) 0.999 Experimental: experimental Organelle PubMed 
Nucleus Nuclear membrane (GO:0031965) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nuclear pore (GO:0005643) 0.999 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.999 Unknown: traceable author statement GO PubMed 
Nucleus PML body (GO:0016605) 0.999 Predicted: inferred from sequence or structural similarity GO PubMed 
Secretory-pathway Cytoplasmic vesicle (GO:0031410) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q8N3Y7

Interaction Score
0.997

Q9UBE8

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein kinase NLK

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.987 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.987 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.987 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.987 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleolus (GO:0005730) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Unknown: traceable author statement GO PubMed 
Membrane Cell junction (GO:0030054) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

Q8N3Y7

Interaction Score
0.996

Q05329

(UniProtKB/Swiss-Prot/P) Details

Glutamate decarboxylase 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.994 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.994 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.994 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 0.994 Unknown: inferred from electronic annotation GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: pTarget method LOCATE PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.931 Experimental: experimental eSLDB PubMed 
Secretory-pathway Golgi membrane (GO:0000139) 0.931 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Synaptic vesicle membrane (GO:0030672) 0.931 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Clathrin sculpted gamma-aminobutyric acid transport vesicle membrane (GO:0061202) 0.931 Unknown: traceable author statement GO PubMed 
Membrane Axon (GO:0030424) 0.976 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.976 Experimental: experimental eSLDB PubMed 
Membrane Anchored to membrane (GO:0031225) 0.976 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.976 Unknown: traceable author statement GO PubMed 
Cytosol Vesicle (GO:0031982) 0.994 Experimental: experimental eSLDB PubMed 
Membrane Cell junction (GO:0030054) 0.976 Unknown: inferred from electronic annotation GO PubMed 
Membrane Inhibitory synapse (GO:0060077) 0.976 Unknown: inferred from electronic annotation GO PubMed 
Membrane Presynaptic membrane (GO:0042734) 0.976 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q8N3Y7

Interaction Score
0.995

Q96Q40

(UniProtKB/Swiss-Prot/P) Details

Cyclin-dependent kinase 15

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.973 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.973 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.973 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Nucleus (GO:0005634) 0.982 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Nucleus (GO:0005634) 0.982 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.982 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q8N3Y7

Interaction Score
0.988

Q9UBD0

(UniProtKB/Swiss-Prot/P) Details

Heat shock transcription factor, X-linked

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.996 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.996 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.996 Experimental: experimental Human Proteinpedia PubMed 
Nucleus Nucleus (GO:0005634) 0.996 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q8N3Y7

Interaction Score
0.907

P02794

(UniProtKB/Swiss-Prot/P) Details

Ferritin heavy chain

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.979 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.979 Unknown: traceable author statement GO PubMed 
Cytosol Intracellular ferritin complex (GO:0008043) 0.979 Unknown: traceable author statement GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.3 Unknown: HDA GO PubMed 
Cytosol Microtubule cytoskeleton (GO:0015630) 0.979 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.3 Unknown: traceable author statement GO PubMed 
Membrane Membrane (GO:0016020) 0.96 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.96 Experimental: experimental Organelle PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.979 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q8N3Y7

Interaction Score
0.72

Q9BWH2

(UniProtKB/Swiss-Prot/P) Details

FUN14 domain-containing protein 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.996 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.996 Experimental: experimental Human Proteinpedia PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.996 Predicted: pTarget method LOCATE PubMed 
Mitochondrion Integral to mitochondrial outer membrane (GO:0031307) 0.996 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Nucleus (GO:0005634) 0.3 Unknown: HDA GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q8N3Y7

Interaction Score
0.72

Q9NU19

(UniProtKB/Swiss-Prot/P) Details

TBC1 domain family member 22B

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Endomembrane system (GO:0012505) 0.937 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Intracellular (GO:0005622) 0.937 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cytosol (GO:0005829) 0.937 Unknown: unspecified method The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.3 Unknown: unspecified method The Human Protein Atlas PubMed 
Membrane Integral to membrane (GO:0016021) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q8N3Y7

Interaction Score
0.602

Q17RD7

(UniProtKB/Swiss-Prot/P) Details

Synaptotagmin-16

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.94 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Plasma membrane (GO:0005886) 0.7 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q8N3Y7

Interaction Score
0.299

P49638

(UniProtKB/Swiss-Prot/P) Details

Alpha-tocopherol transfer protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.958 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.958 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.958 Unknown: traceable author statement GO PubMed 
Secretory-pathway Late endosome (GO:0005770) 0.3 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q8N3Y7

Interaction Score
0

Q08426

(UniProtKB/Swiss-Prot/P) Details

Peroxisomal bifunctional enzyme

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.971 Unknown: traceable author statement GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.91 Predicted: SVM decision tree eSLDB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Peroxisome (GO:0005777) 0.971 Experimental: inferred from direct assay GO PubMed 
Cytosol Peroxisome (GO:0005777) 0.971 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Peroxisomal matrix (GO:0005782) 0.971 Unknown: traceable author statement GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

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ComPPI is published in Nucleic Acids Research Database Issue 2015