Q8NBN3

Transmembrane protein 87A    //   UniProt Profile 

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Species

H. sapiens

Number of Interactions

29 / 36

Average Interaction Score

0.882

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.988 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.988 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Golgi cisterna membrane (GO:0032580) 0.988 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.937 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.937 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.937 Predicted: pTarget method LOCATE PubMed 

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

Q8NBN3

Interaction Score
1

Q92581

(UniProtKB/Swiss-Prot/P) Details

Sodium/hydrogen exchanger 6

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Endomembrane system (GO:0012505) 0.992 Experimental: experimental Organelle PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.992 Experimental: inferred from direct assay GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.992 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.998 Experimental: experimental eSLDB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.998 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.998 Experimental: experimental Organelle PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.998 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 1 Experimental: experimental Organelle PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Recycling endosome membrane (GO:0055038) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Early endosome membrane (GO:0031901) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Late endosome (GO:0005770) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Dendrite (GO:0030425) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Membrane Nerve terminal (GO:0043679) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.999 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.999 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.999 Experimental: experimental Human Proteinpedia PubMed 
Membrane Plasma membrane (GO:0005886) 0.999 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q8NBN3

Interaction Score
1

P08247

(UniProtKB/Swiss-Prot/P) Details

Synaptophysin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Endomembrane system (GO:0012505) 0.96 Experimental: experimental Organelle PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.995 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Synaptic vesicle (GO:0008021) 0.995 Predicted: inferred from sequence or structural similarity GO PubMed 
Secretory-pathway Integral to synaptic vesicle membrane (GO:0030285) 0.995 Predicted: inferred from biological aspect of ancestor GO PubMed 
Secretory-pathway Integral to synaptic vesicle membrane (GO:0030285) 0.995 Experimental: experimental Organelle PubMed 
Membrane Neuron projection (GO:0043005) 0.993 Predicted: inferred from sequence or structural similarity GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.993 Experimental: experimental eSLDB PubMed 
Cytosol Vesicle (GO:0031982) 0.96 Experimental: experimental eSLDB PubMed 
Membrane Cell junction (GO:0030054) 0.993 Unknown: inferred from electronic annotation GO PubMed 
Membrane Neuromuscular junction (GO:0031594) 0.993 Unknown: inferred from electronic annotation GO PubMed 
Membrane Excitatory synapse (GO:0060076) 0.993 Unknown: inferred from electronic annotation GO PubMed 
Membrane Terminal button (GO:0043195) 0.993 Unknown: inferred from electronic annotation GO PubMed 
Membrane Presynaptic active zone (GO:0048786) 0.993 Unknown: inferred from electronic annotation GO PubMed 
Membrane Presynaptic membrane (GO:0042734) 0.993 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q8NBN3

Interaction Score
1

Q9NZ08

(UniProtKB/Swiss-Prot/P) Details

Endoplasmic reticulum aminopeptidase 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.979 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.98 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytosol (GO:0005829) 0.98 Unknown: non-traceable author statement GO PubMed 
Cytosol Cytosol (GO:0005829) 0.98 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.96 Experimental: experimental Human Proteinpedia PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.979 Unknown: non-traceable author statement GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.979 Experimental: experimental Human Proteinpedia PubMed 
Secretory-pathway Endoplasmic reticulum lumen (GO:0005788) 0.979 Unknown: traceable author statement GO PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 0.979 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.992 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.992 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.992 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.992 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 0.994 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 0.994 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.994 Unknown: non-traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.994 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.994 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.98 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q8NBN3

Interaction Score
1

Q13596

(UniProtKB/Swiss-Prot/P) Details

Sorting nexin-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Retromer complex (GO:0030904) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Retromer complex, outer shell (GO:0030905) 1 Predicted: inferred from physical interaction GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Macromolecular complex (GO:0032991) 0.8 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Endosome (GO:0005768) 0.999 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endosome (GO:0005768) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Early endosome membrane (GO:0031901) 0.999 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endosome membrane (GO:0010008) 0.999 Experimental: inferred from direct assay GO PubMed 
Cytosol Lysosome (GO:0005764) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Lysosome (GO:0005764) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Lamellipodium (GO:0030027) 0.958 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.958 Experimental: inferred from direct assay GO PubMed 
Membrane Extrinsic to membrane (GO:0019898) 0.958 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Vesicle (GO:0031982) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q8NBN3

Interaction Score
1

P12830

(UniProtKB/Swiss-Prot/P) Details

Cadherin-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.972 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Trans-Golgi network (GO:0005802) 0.972 Experimental: inferred from mutant phenotype GO PubMed 
Secretory-pathway Endosome (GO:0005768) 0.972 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cortical actin cytoskeleton (GO:0030864) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Actin cytoskeleton (GO:0015629) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Lamellipodium (GO:0030027) 1 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Membrane (GO:0016020) 1 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: pTarget method LOCATE PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Internal side of plasma membrane (GO:0009898) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Lateral plasma membrane (GO:0016328) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Catenin complex (GO:0016342) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Flotillin complex (GO:0016600) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Apical junction complex (GO:0043296) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 
Membrane Cell junction (GO:0030054) 1 Unknown: traceable author statement GO PubMed 
Membrane Cell junction (GO:0030054) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Cell-cell adherens junction (GO:0005913) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q8NBN3

Interaction Score
1

P11279

(UniProtKB/Swiss-Prot/P) Details

Lysosome-associated membrane glycoprotein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Neuronal cell body (GO:0043025) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 1 Experimental: inferred from mutant phenotype GO PubMed 
Secretory-pathway Late endosome (GO:0005770) 0.986 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Multivesicular body (GO:0005771) 0.986 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Endosome membrane (GO:0010008) 0.986 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Lysosome (GO:0005764) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Lysosome (GO:0005764) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytolytic granule (GO:0044194) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Lysosomal membrane (GO:0005765) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Secretory-pathway Melanosome (GO:0042470) 0.986 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Alveolar lamellar body (GO:0097208) 0.986 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Integral to synaptic vesicle membrane (GO:0030285) 0.986 Unknown: inferred from electronic annotation GO PubMed 
Membrane Dendrite (GO:0030425) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.999 Unknown: HDA GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.999 Predicted: SVM decision tree eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.999 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.999 Predicted: pTarget method LOCATE PubMed 
Membrane Plasma membrane (GO:0005886) 0.999 Experimental: experimental Organelle PubMed 
Membrane Sarcolemma (GO:0042383) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Membrane External side of plasma membrane (GO:0009897) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.999 Unknown: traceable author statement GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q8NBN3

Interaction Score
0.999

O15155

(UniProtKB/Swiss-Prot/P) Details

BET1 homolog

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Endomembrane system (GO:0012505) 0.8 Experimental: experimental Organelle PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 0.993 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Endoplasmic reticulum-Golgi intermediate compartment membrane (GO:0033116) 0.993 Unknown: traceable author statement GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.993 Experimental: experimental eSLDB PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.993 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Golgi cisterna (GO:0031985) 0.993 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Golgi membrane (GO:0000139) 0.993 Unknown: traceable author statement GO PubMed 
Secretory-pathway Cis-Golgi network (GO:0005801) 0.993 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Transport vesicle (GO:0030133) 0.993 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.931 Unknown: HDA GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.931 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.931 Unknown: inferred from electronic annotation GO PubMed 
Membrane SNARE complex (GO:0031201) 0.931 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q8NBN3

Interaction Score
0.999

O43493

(UniProtKB/Swiss-Prot/P) Details

Trans-Golgi network integral membrane protein 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.96 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum lumen (GO:0005788) 1 Unknown: traceable author statement GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Trans-Golgi network (GO:0005802) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endosome (GO:0005768) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Secretory-pathway Clathrin coated vesicle membrane (GO:0030665) 1 Unknown: traceable author statement GO PubMed 
Secretory-pathway Transport vesicle (GO:0030133) 1 Unknown: traceable author statement GO PubMed 
Secretory-pathway Trans-Golgi network transport vesicle (GO:0030140) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.853 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.853 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.853 Unknown: traceable author statement GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q8NBN3

Interaction Score
0.999

Q92633

(UniProtKB/Swiss-Prot/P) Details

Lysophosphatidic acid receptor 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Cell surface (GO:0009986) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Neuronal cell body (GO:0043025) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.96 Experimental: experimental Organelle PubMed 
Nucleus Nuclear speck (GO:0016607) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endosome (GO:0005768) 0.96 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endocytic vesicle (GO:0030139) 0.96 Experimental: inferred from direct assay GO PubMed 
Membrane Dendritic shaft (GO:0043198) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Dendritic spine (GO:0043197) 1 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Experimental: experimental eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: pTarget method LOCATE PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Integral to plasma membrane (GO:0005887) 1 Predicted: inferred from sequence or structural similarity GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q8NBN3

Interaction Score
0.999

Q9Y282

(UniProtKB/Swiss-Prot/P) Details

Endoplasmic reticulum-Golgi intermediate compartment protein 3

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.986 Experimental: experimental eSLDB PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 0.986 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Endoplasmic reticulum-Golgi intermediate compartment membrane (GO:0033116) 0.986 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.986 Experimental: experimental eSLDB PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.986 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.853 Unknown: HDA GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.853 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.853 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q8NBN3

Interaction Score
0.997

Q9NY72

(UniProtKB/Swiss-Prot/P) Details

Sodium channel subunit beta-3

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.988 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.8 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Z disc (GO:0030018) 0.988 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Intermediate filament cytoskeleton (GO:0045111) 0.988 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Unknown: non-traceable author statement GO PubMed 
Membrane Voltage-gated sodium channel complex (GO:0001518) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Human Proteinpedia PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q8NBN3

Interaction Score
0.994

Q15005

(UniProtKB/Swiss-Prot/P) Details

Signal peptidase complex subunit 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.937 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 0.937 Unknown: traceable author statement GO PubMed 
Secretory-pathway Signal peptidase complex (GO:0005787) 0.937 Predicted: inferred from biological aspect of ancestor GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.79 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.79 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Organelle membrane (GO:0031090) 0.3 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q8NBN3

Interaction Score
0.993

O00322

(UniProtKB/Swiss-Prot/P) Details

Uroplakin-1a

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Cell surface (GO:0009986) 0.998 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.7 Predicted: inferred from sequence or structural similarity GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.998 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.998 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.998 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.998 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.3 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q8NBN3

Interaction Score
0.987

A2TJK5

(UniProtKB/TrEmbl/P) Details

ERGIC and golgi 3, isoform CRA_a

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.96 Experimental: experimental eSLDB PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.96 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.8 Experimental: experimental eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q8NBN3

Interaction Score
0.981

Q86X19

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 17

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Actin cytoskeleton (GO:0015629) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Ciliary transition zone (GO:0035869) 0.994 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane TCTN-B9D complex (GO:0036038) 0.994 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Cilium membrane (GO:0060170) 0.994 Predicted: inferred from sequence or structural similarity GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.994 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.994 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed 

Q8NBN3

Interaction Score
0.977

P23416

(UniProtKB/Swiss-Prot/P) Details

Glycine receptor subunit alpha-2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Cell projection (GO:0042995) 1 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Predicted: SVM decision tree eSLDB PubMed 
Membrane Chloride channel complex (GO:0034707) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: pTarget method LOCATE PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to plasma membrane (GO:0005887) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Cell junction (GO:0030054) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Postsynaptic membrane (GO:0045211) 1 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q8NBN3

Interaction Score
0.977

Q9P0N5

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 216

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.51 Unknown: traceable author statement GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 0.51 Unknown: inferred from electronic annotation GO PubMed 
Membrane Cilium (GO:0005929) 0.987 Experimental: inferred from direct assay GO PubMed 
Membrane TCTN-B9D complex (GO:0036038) 0.987 Predicted: inferred from sequence or structural similarity GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.987 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.987 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

Q8NBN3

Interaction Score
0.976

Q8IVM8

(UniProtKB/Swiss-Prot/P) Details

Solute carrier family 22 member 9

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.996 Experimental: experimental eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.996 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.996 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Basolateral plasma membrane (GO:0016323) 0.996 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q8NBN3

Interaction Score
0.973

P62079

(UniProtKB/Swiss-Prot/P) Details

Tetraspanin-5

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.988 Experimental: experimental eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.988 Experimental: inferred from direct assay GO PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.988 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q8NBN3

Interaction Score
0.973

Q8WXA8

(UniProtKB/Swiss-Prot/P) Details

5-hydroxytryptamine receptor 3C

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.987 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.987 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.987 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.987 Predicted: pTarget method LOCATE PubMed 
Membrane Plasma membrane (GO:0005886) 0.987 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q8NBN3

Interaction Score
0.962

Q6UX41

(UniProtKB/Swiss-Prot/P) Details

Butyrophilin-like protein 8

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.94 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to membrane (GO:0016021) 0.902 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.902 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.902 Unknown: traceable author statement GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q8NBN3

Interaction Score
0.951

O00116

(UniProtKB/Swiss-Prot/P) Details

Alkyldihydroxyacetonephosphate synthase, peroxisomal

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.999 Unknown: traceable author statement GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.3 Unknown: HDA GO PubMed 
Nucleus Nucleolus (GO:0005730) 0.8 Experimental: inferred from direct assay GO PubMed 
Cytosol Peroxisome (GO:0005777) 0.999 Experimental: experimental eSLDB PubMed 
Cytosol Peroxisome (GO:0005777) 0.999 Experimental: inferred from direct assay GO PubMed 
Cytosol Peroxisome (GO:0005777) 0.999 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Peroxisome (GO:0005777) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Peroxisomal matrix (GO:0005782) 0.999 Unknown: traceable author statement GO PubMed 
Cytosol Peroxisomal membrane (GO:0005778) 0.999 Unknown: HDA GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.86 Experimental: experimental eSLDB PubMed 
Membrane Membrane (GO:0016020) 0.86 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q8NBN3

Interaction Score
0.849

Q9UII7

(UniProtKB/TrEmbl/P) Details

E-cadherin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to membrane (GO:0016021) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q8NBN3

Interaction Score
0.75

Q5VZX0

(UniProtKB/TrEmbl/P) Details

Endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2, isoform CRA_a

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Integral to membrane (GO:0016021) 0.8 Experimental: experimental eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q8NBN3

Interaction Score
0.74

Q00987

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase Mdm2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.972 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.972 Experimental: inferred from mutant phenotype GO PubMed 
Cytosol Cytosol (GO:0005829) 0.972 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleolus (GO:0005730) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear body (GO:0016604) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Macromolecular complex (GO:0032991) 1 Experimental: inferred from mutant phenotype GO PubMed 
Secretory-pathway Endocytic vesicle membrane (GO:0030666) 0.3 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.51 Unknown: traceable author statement GO PubMed 
Membrane Synapse (GO:0045202) 0.51 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q8NBN3

Interaction Score
0.726

A0A1B0GV11

(UniProtKB/TrEmbl/P) Details

Sodium/hydrogen exchanger

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q8NBN3

Interaction Score
0.298

Q9H8X2

(UniProtKB/Swiss-Prot/P) Details

Inositol-pentakisphosphate 2-kinase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Intracellular (GO:0005622) 0.994 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.994 Experimental: experimental eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.994 Unknown: traceable author statement GO PubMed 
Cytosol Cytosol (GO:0005829) 0.994 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.998 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.998 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Nucleolus (GO:0005730) 0.998 Experimental: inferred from mutant phenotype GO PubMed 
Nucleus DNA-directed RNA polymerase I complex (GO:0005736) 0.998 Experimental: inferred from mutant phenotype GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.998 Unknown: traceable author statement GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q8NBN3

Interaction Score
0.282

Q93009

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin carboxyl-terminal hydrolase 7

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.94 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.94 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.999 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.999 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 0.999 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.999 Unknown: traceable author statement GO PubMed 
Nucleus Nuclear body (GO:0016604) 0.999 Unknown: HDA GO PubMed 
Nucleus PML body (GO:0016605) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Macromolecular complex (GO:0032991) 0.999 Experimental: inferred from direct assay GO PubMed 
Nucleus Chromosome (GO:0005694) 0.999 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q8NBN3

Interaction Score
0.21

Q6U8A4

(UniProtKB/TrEmbl/P) Details

Ubiquitin-specific protease 7 isoform

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

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ComPPI is published in Nucleic Acids Research Database Issue 2015