Q8TBB6

Probable cationic amino acid transporter    //   UniProt Profile 

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Species

 H. sapiens

Number of Interactions

 30 / 31

Average Interaction Score

 0.864

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Lysosomal membrane (GO:0005765) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.981 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.981 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.981 Predicted: pTarget method LOCATE PubMed 
Membrane Plasma membrane (GO:0005886) 0.981 Predicted: PAML algorithm PA-GOSUB PubMed 

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

Q8TBB6

Interaction Score
0.995

P63027

(UniProtKB/Swiss-Prot/P) Details

Vesicle-associated membrane protein 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.996 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.996 Unknown: traceable author statement GO PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 0.996 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.996 Predicted: inferred from sequence or structural similarity GO PubMed 
Secretory-pathway Trans-Golgi network (GO:0005802) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Secretory-pathway Cytoplasmic vesicle (GO:0031410) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Secretory-pathway Secretory granule (GO:0030141) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Secretory-pathway Secretory granule membrane (GO:0030667) 1 Unknown: traceable author statement GO PubMed 
Secretory-pathway Zymogen granule membrane (GO:0042589) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Secretory-pathway Clathrin-coated vesicle (GO:0030136) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Clathrin coated vesicle membrane (GO:0030665) 1 Unknown: traceable author statement GO PubMed 
Secretory-pathway Synaptic vesicle (GO:0008021) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Secretory-pathway Synaptic vesicle membrane (GO:0030672) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Secretory-pathway Clathrin sculpted glutamate transport vesicle membrane (GO:0060203) 1 Unknown: traceable author statement GO PubMed 
Secretory-pathway Clathrin sculpted monoamine transport vesicle membrane (GO:0070083) 1 Unknown: traceable author statement GO PubMed 
Secretory-pathway Clathrin sculpted gamma-aminobutyric acid transport vesicle membrane (GO:0061202) 1 Unknown: traceable author statement GO PubMed 
Membrane Neuron projection (GO:0043005) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Neuron projection terminus (GO:0044306) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Integral to membrane (GO:0016021) 1 Predicted: SVM decision tree eSLDB PubMed 
Membrane Voltage-gated potassium channel complex (GO:0008076) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane SNARE complex (GO:0031201) 1 Unknown: traceable author statement GO PubMed 
Membrane Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex (GO:0070033) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Synaptobrevin 2-SNAP-25-syntaxin-1a complex (GO:0070044) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex (GO:0070032) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Integral to plasma membrane (GO:0005887) 1 Unknown: traceable author statement GO PubMed 
Cytosol Vesicle (GO:0031982) 0.996 Experimental: inferred from direct assay GO PubMed 
Membrane Cell junction (GO:0030054) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Synapse (GO:0045202) 1 Predicted: inferred from sequence or structural similarity GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q8TBB6

Interaction Score
0.994

Q13651

(UniProtKB/Swiss-Prot/P) Details

Interleukin-10 receptor subunit alpha

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.94 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to membrane (GO:0016021) 0.995 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.995 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.995 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.995 Experimental: experimental Organelle PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q8TBB6

Interaction Score
0.994

P19397

(UniProtKB/Swiss-Prot/P) Details

Leukocyte surface antigen CD53

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Cell surface (GO:0009986) 1 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Tertiary granule membrane (GO:0070821) 0.3 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Experimental: experimental eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Immunological synapse (GO:0001772) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Integral to plasma membrane (GO:0005887) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.3 Unknown: HDA GO PubMed 
Membrane Cell-cell junction (GO:0005911) 1 Predicted: inferred from sequence or structural similarity GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q8TBB6

Interaction Score
0.994

Q9BSR8

(UniProtKB/Swiss-Prot/P) Details

Protein YIPF4

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.96 Experimental: inferred from direct assay GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.998 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.998 Experimental: experimental Human Proteinpedia PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.998 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.998 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.994 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.994 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.994 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.994 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q8TBB6

Interaction Score
0.993

P42857

(UniProtKB/Swiss-Prot/P) Details

Neuronal vesicle trafficking-associated protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.853 Unknown: traceable author statement GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.853 Predicted: pTarget method LOCATE PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.86 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 0.86 Experimental: experimental Organelle PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 1 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 1 Experimental: experimental eSLDB PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Golgi cisterna membrane (GO:0032580) 1 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Trans-Golgi network membrane (GO:0032588) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Secretory-pathway Endosome (GO:0005768) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Secretory-pathway Recycling endosome membrane (GO:0055038) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Secretory-pathway Early endosome membrane (GO:0031901) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Secretory-pathway Late endosome (GO:0005770) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Secretory-pathway Multivesicular body membrane (GO:0032585) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Lysosomal lumen (GO:0043202) 0.853 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Cytoplasmic vesicle membrane (GO:0030659) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Dendrite (GO:0030425) 0.991 Predicted: inferred from sequence or structural similarity GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.991 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.991 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Lateral plasma membrane (GO:0016328) 0.991 Unknown: inferred from electronic annotation GO PubMed 
Membrane Postsynaptic membrane (GO:0045211) 0.991 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q8TBB6

Interaction Score
0.99

O00767

(UniProtKB/Swiss-Prot/P) Details

Acyl-CoA desaturase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleolus (GO:0005730) 0.8 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 1 Experimental: experimental eSLDB PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 1 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.992 Unknown: HDA GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.992 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.992 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.992 Predicted: pTarget method LOCATE PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q8TBB6

Interaction Score
0.989

O95236

(UniProtKB/Swiss-Prot/P) Details

Apolipoprotein L3

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.79 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.79 Unknown: inferred from electronic annotation GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nuclear body (GO:0016604) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.958 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 0.958 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.958 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q8TBB6

Interaction Score
0.989

Q14162

(UniProtKB/Swiss-Prot/P) Details

Scavenger receptor class F member 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.79 Predicted: SVM decision tree eSLDB PubMed 
Secretory-pathway Endocytic vesicle membrane (GO:0030666) 0.79 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to membrane (GO:0016021) 0.972 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.972 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.972 Experimental: experimental Human Proteinpedia PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q8TBB6

Interaction Score
0.987

Q9BUN8

(UniProtKB/Swiss-Prot/P) Details

Derlin-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Signal recognition particle (GO:0048500) 0.8 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 1 Experimental: experimental eSLDB PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 1 Predicted: pTarget method LOCATE PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Signal recognition particle receptor complex (GO:0005785) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 1 Unknown: traceable author statement GO PubMed 
Secretory-pathway Cdc48p-Npl4p-Ufd1p AAA ATPase complex (GO:0034098) 1 Unknown: traceable author statement GO PubMed 
Secretory-pathway Integral to endoplasmic reticulum membrane (GO:0030176) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Early endosome (GO:0005769) 1 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Late endosome (GO:0005770) 1 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.972 Unknown: HDA GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.972 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.972 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q8TBB6

Interaction Score
0.985

Q9Y5Z9

(UniProtKB/Swiss-Prot/P) Details

UbiA prenyltransferase domain-containing protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.992 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.992 Experimental: inferred from direct assay GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.992 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.937 Predicted: pTarget method LOCATE PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.937 Predicted: PAML algorithm PA-GOSUB PubMed 
Mitochondrion Mitochondrial membrane (GO:0031966) 0.937 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.96 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.96 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.972 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 0.972 Unknown: traceable author statement GO PubMed 
Secretory-pathway Integral to Golgi membrane (GO:0030173) 0.972 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.96 Experimental: inferred from direct assay GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.96 Experimental: experimental eSLDB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q8TBB6

Interaction Score
0.983

P62136

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Protein phosphatase type 1 complex (GO:0000164) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol PTW/PP1 phosphatase complex (GO:0072357) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Perikaryon (GO:0043204) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Glycogen granule (GO:0042587) 1 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Human Proteinpedia PubMed 
Nucleus Nucleolus (GO:0005730) 1 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nuclear chromosome, telomeric region (GO:0000784) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Dendritic spine (GO:0043197) 0.994 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.994 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.994 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 
Membrane Cell-cell adherens junction (GO:0005913) 0.994 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q8TBB6

Interaction Score
0.98

Q12981

(UniProtKB/Swiss-Prot/P) Details

Vesicle transport protein SEC20

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Endomembrane system (GO:0012505) 0.992 Experimental: experimental Organelle PubMed 
Cytosol Cytoplasm (GO:0005737) 0.992 Experimental: inferred from direct assay GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.992 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrial membrane (GO:0031966) 0.8 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.96 Experimental: experimental Organelle PubMed 
Nucleus Nuclear envelope (GO:0005635) 0.96 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.999 Experimental: experimental eSLDB PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.999 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 0.999 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Integral to endoplasmic reticulum membrane (GO:0030176) 0.999 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.94 Predicted: SVM decision tree eSLDB PubMed 
Membrane SNARE complex (GO:0031201) 0.94 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q8TBB6

Interaction Score
0.978

Q8N4V1

(UniProtKB/Swiss-Prot/P) Details

Membrane magnesium transporter 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.999 Predicted: SVM decision tree eSLDB PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.999 Experimental: experimental Human Proteinpedia PubMed 
Secretory-pathway ER membrane protein complex (GO:0072546) 0.999 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.999 Predicted: inferred from sequence or structural similarity GO PubMed 
Secretory-pathway Golgi membrane (GO:0000139) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Early endosome (GO:0005769) 0.999 Predicted: inferred from sequence or structural similarity GO PubMed 
Secretory-pathway Early endosome membrane (GO:0031901) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.958 Unknown: HDA GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.958 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.958 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q8TBB6

Interaction Score
0.978

Q9NZG7

(UniProtKB/Swiss-Prot/P) Details

Ninjurin-2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.958 Predicted: SVM decision tree eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.958 Experimental: experimental Organelle PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.958 Unknown: traceable author statement GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q8TBB6

Interaction Score
0.976

O15155

(UniProtKB/Swiss-Prot/P) Details

BET1 homolog

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Endomembrane system (GO:0012505) 0.8 Experimental: experimental Organelle PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 0.993 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Endoplasmic reticulum-Golgi intermediate compartment membrane (GO:0033116) 0.993 Unknown: traceable author statement GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.993 Experimental: experimental eSLDB PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.993 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Golgi cisterna (GO:0031985) 0.993 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Golgi membrane (GO:0000139) 0.993 Unknown: traceable author statement GO PubMed 
Secretory-pathway Cis-Golgi network (GO:0005801) 0.993 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Transport vesicle (GO:0030133) 0.993 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.931 Unknown: HDA GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.931 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.931 Unknown: inferred from electronic annotation GO PubMed 
Membrane SNARE complex (GO:0031201) 0.931 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q8TBB6

Interaction Score
0.969

Q9ULC5

(UniProtKB/Swiss-Prot/P) Details

Long-chain-fatty-acid--CoA ligase 5

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Mitochondrion Mitochondrion (GO:0005739) 0.994 Experimental: experimental eSLDB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.994 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.994 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Mitochondrion Mitochondrial outer membrane (GO:0005741) 0.994 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleolus (GO:0005730) 0.992 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.86 Experimental: experimental eSLDB PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 0.86 Unknown: traceable author statement GO PubMed 
Cytosol Peroxisome (GO:0005777) 0.8 Experimental: experimental eSLDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.902 Unknown: HDA GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.902 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.902 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q8TBB6

Interaction Score
0.969

Q8IY26

(UniProtKB/Swiss-Prot/P) Details

Phospholipid phosphatase 6

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.902 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.902 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.902 Unknown: traceable author statement GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q8TBB6

Interaction Score
0.961

O75063

(UniProtKB/Swiss-Prot/P) Details

Glycosaminoglycan xylosylkinase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.998 Experimental: experimental eSLDB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.96 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.998 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.998 Predicted: pTarget method LOCATE PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.998 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Golgi membrane (GO:0000139) 0.998 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Membrane (GO:0016020) 0.86 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.86 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q8TBB6

Interaction Score
0.952

Q8NHW4

(UniProtKB/Swiss-Prot/P) Details

C-C motif chemokine 4-like

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.973 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular region (GO:0005576) 0.973 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.973 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q8TBB6

Interaction Score
0.941

Q7Z2K6

(UniProtKB/Swiss-Prot/P) Details

Endoplasmic reticulum metallopeptidase 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleolus (GO:0005730) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.853 Unknown: HDA GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.853 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.853 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q8TBB6

Interaction Score
0.938

Q96EC8

(UniProtKB/Swiss-Prot/P) Details

Protein YIPF6

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 1 Experimental: experimental Human Proteinpedia PubMed 
Secretory-pathway Golgi trans cisterna (GO:0000138) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi medial cisterna (GO:0005797) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi membrane (GO:0000139) 1 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Cis-Golgi network (GO:0005801) 1 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Trans-Golgi network (GO:0005802) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway ER to Golgi transport vesicle (GO:0030134) 1 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.79 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.79 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q8TBB6

Interaction Score
0.938

Q9P0B6

(UniProtKB/Swiss-Prot/P) Details

Coiled-coil domain-containing protein 167

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.79 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.79 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q8TBB6

Interaction Score
0.919

O95159

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein-like 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.3 Unknown: non-traceable author statement GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.96 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.79 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.79 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q8TBB6

Interaction Score
0.799

Q969F0

(UniProtKB/Swiss-Prot/P) Details

Fetal and adult testis-expressed transcript protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Mitochondrion Mitochondrial outer membrane (GO:0005741) 0.8 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: pTarget method LOCATE PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.972 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.972 Experimental: experimental Human Proteinpedia PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 0.972 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.3 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q8TBB6

Interaction Score
0.769

Q5JX71

(UniProtKB/Swiss-Prot/P) Details

Protein FAM209A

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.3 Unknown: HDA GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.3 Unknown: HDA GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q8TBB6

Interaction Score
0.746

Q9BQB6

(UniProtKB/Swiss-Prot/P) Details

Vitamin K epoxide reductase complex subunit 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.992 Predicted: SVM decision tree eSLDB PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.992 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.992 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 0.992 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.3 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q8TBB6

Interaction Score
0.687

A0A0C4DFN3

(UniProtKB/TrEmbl/P) Details

Monoglyceride lipase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Integral to membrane (GO:0016021) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q8TBB6

Interaction Score
0.3

Q12982

(UniProtKB/Swiss-Prot/P) Details

BCL2/adenovirus E1B 19 kDa protein-interacting protein 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Endomembrane system (GO:0012505) 1 Experimental: experimental Organelle PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Experimental: experimental Organelle PubMed 
Nucleus Nuclear envelope (GO:0005635) 0.992 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q8TBB6

Interaction Score
0.21

Q9Y680

(UniProtKB/Swiss-Prot/P) Details

Peptidyl-prolyl cis-trans isomerase FKBP7

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.987 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: inferred from biological aspect of ancestor GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.987 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.987 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum lumen (GO:0005788) 0.987 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q8TBB6

Interaction Score
0

A5D903

(UniProtKB/TrEmbl/P) Details

PRB1 protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

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ComPPI is published in Nucleic Acids Research Database Issue 2015