Q8TD43

Transient receptor potential cation channel subfamily M member 4 // UniProt Profile

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Species	H. sapiens
Number of Interactions	12 / 13
Average Interaction Score	0.959

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Neuronal cell body (GO:0043025)	0.91	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.91	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.96	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.96	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Sodium channel complex (GO:0034706)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Fully spanning plasma membrane (GO:0044214)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

Q8TD43

Interaction Score

P40259

(UniProtKB/Swiss-Prot/P) Details

B-cell antigen receptor complex-associated protein beta chain

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	B cell receptor complex (GO:0019815)	0.999	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.971	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.971	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.971	Unknown: unspecified method	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.86	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.86	Unknown: unspecified method	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.8	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Unknown: unspecified method	The Human Protein Atlas	PubMed
Membrane	External side of plasma membrane (GO:0009897)	0.999	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	0.999	Unknown: traceable author statement	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.971	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q8TD43

Interaction Score

Q9H6D8

(UniProtKB/Swiss-Prot/P) Details

Fibronectin type III domain-containing protein 4

Q8TD43

Interaction Score

O00322

(UniProtKB/Swiss-Prot/P) Details

Uroplakin-1a

Q8TD43

Interaction Score

Q9NWB7

(UniProtKB/Swiss-Prot/P) Details

Intraflagellar transport protein 57 homolog

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.91	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.91	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cilium basal body (GO:0036064)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Axoneme (GO:0005930)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Intraflagellar transport particle B (GO:0030992)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Dendrite terminus (GO:0044292)	0.853	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Cilium (GO:0005929)	0.853	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Photoreceptor connecting cilium (GO:0032391)	0.853	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q8TD43

Interaction Score

0.999

O00214

(UniProtKB/Swiss-Prot/P) Details

Galectin-8

Q8TD43

Interaction Score

0.999

P14866

(UniProtKB/Swiss-Prot/P) Details

Heterogeneous nuclear ribonucleoprotein L

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Ribonucleoprotein complex (GO:0030529)	0.999	Experimental: experimental	Organelle	PubMed
Cytosol	Ribonucleoprotein granule (GO:0035770)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.999	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q8TD43

Interaction Score

0.998

Q7Z2W7

(UniProtKB/Swiss-Prot/P) Details

Transient receptor potential cation channel subfamily M member 8

Q8TD43

Interaction Score

0.996

Q8WV48

(UniProtKB/Swiss-Prot/P) Details

Coiled-coil domain-containing protein 107

Q8TD43

Interaction Score

0.996

P35637

(UniProtKB/Swiss-Prot/P) Details

RNA-binding protein FUS

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Perikaryon (GO:0043204)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.931	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Polysome (GO:0005844)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Dendritic spine head (GO:0044327)	0.3	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q8TD43

Interaction Score

0.943

Q13344

(UniProtKB/TrEmbl/P) Details

Fus-like protein

Q8TD43

Interaction Score

0.902

Q6IBQ5

(UniProtKB/TrEmbl/P) Details

FUS protein

Q8TD43

Interaction Score

0.672

Q6NTA2

(UniProtKB/TrEmbl/P) Details

HNRNPL protein

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Q8TD43

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

Q8TD43

P40259

B-cell antigen receptor complex-associated protein beta chain

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q8TD43

Q9H6D8

Fibronectin type III domain-containing protein 4

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q8TD43

O00322

Uroplakin-1a

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q8TD43

Q9NWB7

Intraflagellar transport protein 57 homolog

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q8TD43

O00214

Galectin-8

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q8TD43

P14866

Heterogeneous nuclear ribonucleoprotein L

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q8TD43

Q7Z2W7

Transient receptor potential cation channel subfamily M member 8

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q8TD43

Q8WV48

Coiled-coil domain-containing protein 107

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q8TD43

P35637

RNA-binding protein FUS

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q8TD43

Q13344

Fus-like protein

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q8TD43

Q6IBQ5

FUS protein

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q8TD43

Q6NTA2

HNRNPL protein

Localizations:

Interaction Source Database:

Interaction Source Publication: