Q8WZ73

E3 ubiquitin-protein ligase rififylin    //   UniProt Profile 

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Species

H. sapiens

Number of Interactions

43 / 60

Average Interaction Score

0.912

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
N/A Tumor necrosis factor receptor superfamily complex (GO:0002947) 0.8 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.79 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.79 Unknown: traceable author statement GO PubMed 
Secretory-pathway Golgi membrane (GO:0000139) 0.972 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Recycling endosome membrane (GO:0055038) 0.972 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Endosome membrane (GO:0010008) 0.972 Experimental: inferred from direct assay GO PubMed 
Cytosol Lysosome (GO:0005764) 1 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.972 Experimental: experimental eSLDB PubMed 
Membrane Membrane (GO:0016020) 0.972 Unknown: HDA GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.972 Experimental: inferred from direct assay GO PubMed 

First-Neighbour Network Visualization

Toggle Display
Q9BZL6Q13546P31947Q14790P51668A8K855P12036Q14674P54252P62837Q969K3Q6IPM2P04637P61077P45974P29353Q9Y5K5Q00987Q92783Q14258Q96FW1Q93009P60604A0A087WW00D6RAH7Q53GA5C9JQV6A0A0A0MS38Q96RU2A0A087WX45A0A087WX19G3XA89Q9H3M9B3KUV5Q96DC9B4E3L3A0A087WTM5Q6U8A4A0A087X1Q1A0A087WT22A0A087WXZ1A7UKX8Q96DS0Q8WZ73

The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

Q8WZ73

Interaction Score
1

Q9BZL6

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein kinase D2

Q8WZ73

Interaction Score
1

Q13546

(UniProtKB/Swiss-Prot/P) Details

Receptor-interacting serine/threonine-protein kinase 1

Q8WZ73

Interaction Score
1

P31947

(UniProtKB/Swiss-Prot/P) Details

14-3-3 protein sigma

Q8WZ73

Interaction Score
1

Q14790

(UniProtKB/Swiss-Prot/P) Details

Caspase-8

Q8WZ73

Interaction Score
1

P51668

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin-conjugating enzyme E2 D1

Q8WZ73

Interaction Score
1

A8K855

(UniProtKB/Swiss-Prot/P) Details

EF-hand calcium-binding domain-containing protein 7

Q8WZ73

Interaction Score
1

P12036

(UniProtKB/Swiss-Prot/P) Details

Neurofilament heavy polypeptide

Q8WZ73

Interaction Score
1

Q14674

(UniProtKB/Swiss-Prot/P) Details

Separin

Q8WZ73

Interaction Score
1

P54252

(UniProtKB/Swiss-Prot/P) Details

Ataxin-3

Q8WZ73

Interaction Score
1

P62837

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin-conjugating enzyme E2 D2

Q8WZ73

Interaction Score
1

Q969K3

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase RNF34

Q8WZ73

Interaction Score
1

Q6IPM2

(UniProtKB/Swiss-Prot/P) Details

IQ domain-containing protein E

Q8WZ73

Interaction Score
1

P04637

(UniProtKB/Swiss-Prot/P) Details

Cellular tumor antigen p53

Q8WZ73

Interaction Score
1

P61077

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin-conjugating enzyme E2 D3

Q8WZ73

Interaction Score
1

P45974

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin carboxyl-terminal hydrolase 5

Q8WZ73

Interaction Score
1

P29353

(UniProtKB/Swiss-Prot/P) Details

SHC-transforming protein 1

Q8WZ73

Interaction Score
0.999

Q9Y5K5

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin carboxyl-terminal hydrolase isozyme L5

Q8WZ73

Interaction Score
0.998

Q00987

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase Mdm2

Q8WZ73

Interaction Score
0.998

Q92783

(UniProtKB/Swiss-Prot/P) Details

Signal transducing adapter molecule 1

Q8WZ73

Interaction Score
0.997

Q14258

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin/ISG15 ligase TRIM25

Q8WZ73

Interaction Score
0.993

Q96FW1

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin thioesterase OTUB1

Q8WZ73

Interaction Score
0.987

Q93009

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin carboxyl-terminal hydrolase 7

Q8WZ73

Interaction Score
0.985

P60604

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin-conjugating enzyme E2 G2

Q8WZ73

Interaction Score
0.955

A0A087WW00

(UniProtKB/TrEmbl/P) Details

Ubiquitin-conjugating enzyme E2 D1

Q8WZ73

Interaction Score
0.955

D6RAH7

(UniProtKB/TrEmbl/P) Details

Ubiquitin-conjugating enzyme E2 D3

Q8WZ73

Interaction Score
0.948

Q53GA5

(UniProtKB/TrEmbl/P) Details

Cellular tumor antigen p53

Q8WZ73

Interaction Score
0.946

C9JQV6

(UniProtKB/TrEmbl/P) Details

Ataxin-3

Q8WZ73

Interaction Score
0.946

A0A0A0MS38

(UniProtKB/TrEmbl/P) Details

Ataxin-3

Q8WZ73

Interaction Score
0.937

Q96RU2

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin carboxyl-terminal hydrolase 28

Q8WZ73

Interaction Score
0.926

A0A087WX45

(UniProtKB/TrEmbl/P) Details

IQ domain-containing protein E

Q8WZ73

Interaction Score
0.926

A0A087WX19

(UniProtKB/TrEmbl/P) Details

IQ domain-containing protein E

Q8WZ73

Interaction Score
0.923

G3XA89

(UniProtKB/TrEmbl/P) Details

E3 ubiquitin-protein ligase Mdm2

Q8WZ73

Interaction Score
0.921

Q9H3M9

(UniProtKB/Swiss-Prot/P) Details

Ataxin-3-like protein

Q8WZ73

Interaction Score
0.8

B3KUV5

(UniProtKB/TrEmbl/P) Details

cDNA FLJ40710 fis, clone THYMU2027125, highly similar to Ubiquitin thioesterase protein OTUB1

Q8WZ73

Interaction Score
0.771

Q96DC9

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin thioesterase OTUB2

Q8WZ73

Interaction Score
0.758

B4E3L3

(UniProtKB/TrEmbl/P) Details

cDNA FLJ58236, highly similar to Ubiquitin carboxyl-terminal hydrolase 28

Q8WZ73

Interaction Score
0.758

A0A087WTM5

(UniProtKB/TrEmbl/P) Details

E3 ubiquitin-protein ligase RNF34

Q8WZ73

Interaction Score
0.7

Q6U8A4

(UniProtKB/TrEmbl/P) Details

Ubiquitin-specific protease 7 isoform

Q8WZ73

Interaction Score
0.632

A0A087X1Q1

(UniProtKB/TrEmbl/P) Details

Cellular tumor antigen p53

Q8WZ73

Interaction Score
0.632

A0A087WT22

(UniProtKB/TrEmbl/P) Details

Cellular tumor antigen p53

Q8WZ73

Interaction Score
0.632

A0A087WXZ1

(UniProtKB/TrEmbl/P) Details

Cellular tumor antigen p53

Q8WZ73

Interaction Score
0.632

A7UKX8

(UniProtKB/TrEmbl/P) Details

E3 ubiquitin-protein ligase Mdm2

Q8WZ73

Interaction Score
0.553

Q96DS0

(UniProtKB/TrEmbl/P) Details

MDM2 variant FB55

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ComPPI is published in Nucleic Acids Research Database Issue 2015