Q92643

GPI-anchor transamidase // UniProt Profile

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Species	H. sapiens
Number of Interactions	13 / 18
Average Interaction Score	0.972

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.994	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.994	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.994	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Integral to endoplasmic reticulum membrane (GO:0030176)	0.994	Unknown: non-traceable author statement	GO	PubMed
Secretory-pathway	GPI-anchor transamidase complex (GO:0042765)	0.994	Experimental: inferred from mutant phenotype	GO	PubMed
Cytosol	Lysosome (GO:0005764)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.86	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.86	Experimental: experimental	eSLDB	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

Q92643

Interaction Score

P27824

(UniProtKB/Swiss-Prot/P) Details

Calnexin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Myelin sheath (GO:0043209)	0.966	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Neuronal cell body (GO:0043025)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Ribosome (GO:0005840)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Rough endoplasmic reticulum (GO:0005791)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Smooth endoplasmic reticulum (GO:0005790)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum lumen (GO:0005788)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Integral to lumenal side of endoplasmic reticulum membrane (GO:0071556)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum quality control compartment (GO:0044322)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Melanosome (GO:0042470)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendrite cytoplasm (GO:0032839)	0.966	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendritic spine (GO:0043197)	0.966	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Axon (GO:0030424)	0.966	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.96	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.96	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.966	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.966	Experimental: experimental	eSLDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.657	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q92643

Interaction Score

O43292

(UniProtKB/Swiss-Prot/P) Details

Glycosylphosphatidylinositol anchor attachment 1 protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endomembrane system (GO:0012505)	0.94	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.998	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.998	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.998	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Integral to endoplasmic reticulum membrane (GO:0030176)	0.998	Experimental: experimental	Organelle	PubMed
Secretory-pathway	GPI-anchor transamidase complex (GO:0042765)	0.998	Unknown: traceable author statement	GO	PubMed
Cytosol	Lysosome (GO:0005764)	0.94	Predicted: pTarget method	LOCATE	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.79	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.79	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

HPRD, BioGRID

Interaction Source Publication:

PubMed

, PubMed

Q92643

Interaction Score

Q9BZM5

(UniProtKB/Swiss-Prot/P) Details

UL16-binding protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.958	Experimental: experimental	eSLDB	PubMed
Membrane	Cell surface (GO:0009986)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.958	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.958	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Lysosome (GO:0005764)	0.94	Predicted: pTarget method	LOCATE	PubMed
Extracellular	Extracellular region (GO:0005576)	0.992	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.992	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.992	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.992	Experimental: inferred from direct assay	GO	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Anchored to plasma membrane (GO:0046658)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q92643

Interaction Score

0.999

Q9H490

(UniProtKB/Swiss-Prot/P) Details

Phosphatidylinositol glycan anchor biosynthesis class U protein

Q92643

Interaction Score

0.999

Q969N2

(UniProtKB/Swiss-Prot/P) Details

GPI transamidase component PIG-T

Q92643

Interaction Score

0.997

O95274

(UniProtKB/Swiss-Prot/P) Details

Ly6/PLAUR domain-containing protein 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.971	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.971	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.971	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.971	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.986	Experimental: experimental	eSLDB	PubMed
Membrane	Membrane (GO:0016020)	0.986	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.986	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.986	Unknown: traceable author statement	GO	PubMed
Membrane	Anchored to plasma membrane (GO:0046658)	0.986	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q92643

Interaction Score

0.993

Q6NUS6

(UniProtKB/Swiss-Prot/P) Details

Tectonic-3

Q92643

Interaction Score

0.987

Q9UI38

(UniProtKB/Swiss-Prot/P) Details

Probable threonine protease PRSS50

Q92643

Interaction Score

0.982

Q96S52

(UniProtKB/Swiss-Prot/P) Details

GPI transamidase component PIG-S

Q92643

Interaction Score

0.98

Q9Y2A9

(UniProtKB/Swiss-Prot/P) Details

N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3

Q92643

Interaction Score

0.962

Q8NBL9

(UniProtKB/TrEmbl/P) Details

cDNA PSEC0119 fis, clone PLACE1002376, highly similar to GPI transamidase component PIG-S

Q92643

Interaction Score

0.949

P05187

(UniProtKB/Swiss-Prot/P) Details

Alkaline phosphatase, placental type

Q92643

Interaction Score

0.788

Q9NRD1

(UniProtKB/Swiss-Prot/P) Details

F-box only protein 6

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Q92643

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

Q92643

P27824

Calnexin

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q92643

O43292

Glycosylphosphatidylinositol anchor attachment 1 protein

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q92643

Q9BZM5

UL16-binding protein 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q92643

Q9H490

Phosphatidylinositol glycan anchor biosynthesis class U protein

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q92643

Q969N2

GPI transamidase component PIG-T

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q92643

O95274

Ly6/PLAUR domain-containing protein 3

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q92643

Q6NUS6

Tectonic-3

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q92643

Q9UI38

Probable threonine protease PRSS50

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q92643

Q96S52

GPI transamidase component PIG-S

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q92643

Q9Y2A9

N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q92643

Q8NBL9

cDNA PSEC0119 fis, clone PLACE1002376, highly similar to GPI transamidase component PIG-S

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q92643

P05187

Alkaline phosphatase, placental type

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q92643