Q969Z0

FAST kinase domain-containing protein 4 // UniProt Profile

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Species	H. sapiens
Number of Interactions	68 / 86
Average Interaction Score	0.513

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.998	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial matrix (GO:0005759)	0.998	Experimental: inferred from direct assay	GO	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

Q969Z0

Interaction Score

0.999

Q8TCS8

(UniProtKB/Swiss-Prot/P) Details

Polyribonucleotide nucleotidyltransferase 1, mitochondrial

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.992	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Polysomal ribosome (GO:0042788)	0.992	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.992	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial degradosome (GO:0045025)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial intermembrane space (GO:0005758)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q969Z0

Interaction Score

0.999

P52815

(UniProtKB/Swiss-Prot/P) Details

39S ribosomal protein L12, mitochondrial

Q969Z0

Interaction Score

0.999

O00483

(UniProtKB/Swiss-Prot/P) Details

Cytochrome c oxidase subunit NDUFA4

Q969Z0

Interaction Score

0.998

Q9P032

(UniProtKB/Swiss-Prot/P) Details

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4

Q969Z0

Interaction Score

0.997

Q9UBX3

(UniProtKB/Swiss-Prot/P) Details

Mitochondrial dicarboxylate carrier

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: experimental	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	0.999	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.972	Unknown: HDA	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.972	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.972	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.91	Predicted: inferred from biological aspect of ancestor	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q969Z0

Interaction Score

0.997

Q96I51

(UniProtKB/Swiss-Prot/P) Details

RCC1-like G exchanging factor-like protein

Q969Z0

Interaction Score

0.995

Q9Y6E7

(UniProtKB/Swiss-Prot/P) Details

NAD-dependent protein lipoamidase sirtuin-4, mitochondrial

Q969Z0

Interaction Score

0.993

O75208

(UniProtKB/Swiss-Prot/P) Details

Ubiquinone biosynthesis protein COQ9, mitochondrial

Q969Z0

Interaction Score

0.989

P14854

(UniProtKB/Swiss-Prot/P) Details

Cytochrome c oxidase subunit 6B1

Q969Z0

Interaction Score

0.985

Q96MF6

(UniProtKB/Swiss-Prot/P) Details

Coenzyme Q-binding protein COQ10 homolog A, mitochondrial

Q969Z0

Interaction Score

0.958

A1L188

(UniProtKB/Swiss-Prot/P) Details

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 8

Q969Z0

Interaction Score

0.908

Q9C002

(UniProtKB/Swiss-Prot/P) Details

Normal mucosa of esophagus-specific gene 1 protein

Q969Z0

Interaction Score

0.786

P35613

(UniProtKB/Swiss-Prot/P) Details

Basigin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.897	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.992	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.3	Unknown: HDA	GO	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.897	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Melanosome (GO:0042470)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Acrosomal membrane (GO:0002080)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.999	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.999	Experimental: experimental	eSLDB	PubMed
Membrane	Membrane raft (GO:0045121)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Sarcolemma (GO:0042383)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.992	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.999	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q969Z0

Interaction Score

0.7

Q13137

(UniProtKB/Swiss-Prot/P) Details

Calcium-binding and coiled-coil domain-containing protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.958	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.958	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	0.958	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Autophagic vacuole (GO:0005776)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Autophagic vacuole membrane (GO:0000421)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

Q969Z0

Interaction Score

0.7

Q9UQV4

(UniProtKB/Swiss-Prot/P) Details

Lysosome-associated membrane glycoprotein 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Early endosome (GO:0005769)	0.94	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Lysosome (GO:0005764)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Lysosomal membrane (GO:0005765)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Lysosomal membrane (GO:0005765)	1	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Alveolar lamellar body membrane (GO:0097233)	0.94	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.987	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.987	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.987	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.987	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Vesicle (GO:0031982)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q969Z0

Interaction Score

0.7

Q6RW13

(UniProtKB/Swiss-Prot/P) Details

Type-1 angiotensin II receptor-associated protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.996	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cell cortex (GO:0005938)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.96	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.996	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.996	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle membrane (GO:0030659)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.902	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Vesicle (GO:0031982)	1	Experimental: experimental	eSLDB	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

Q969Z0

Interaction Score

0.7

Q9HCE1

(UniProtKB/Swiss-Prot/P) Details

Putative helicase MOV-10

Q969Z0

Interaction Score

0.699

P62834

(UniProtKB/Swiss-Prot/P) Details

Ras-related protein Rap-1A

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Myelin sheath (GO:0043209)	0.979	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Unknown: traceable author statement	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Guanyl-nucleotide exchange factor complex (GO:0032045)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	0.937	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Late endosome (GO:0005770)	0.937	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Phagocytic vesicle (GO:0045335)	0.937	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Neuron projection (GO:0043005)	0.979	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.979	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.979	Unknown: traceable author statement	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.999	Unknown: HDA	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.979	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q969Z0

Interaction Score

0.699

O43150

(UniProtKB/Swiss-Prot/P) Details

Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2

Q969Z0

Interaction Score

0.698

Q96D09

(UniProtKB/Swiss-Prot/P) Details

G-protein coupled receptor-associated sorting protein 2

Q969Z0

Interaction Score

0.696

Q9NRY5

(UniProtKB/Swiss-Prot/P) Details

Protein FAM114A2

Q969Z0

Interaction Score

0.692

Q14258

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin/ISG15 ligase TRIM25

Q969Z0

Interaction Score

0.692

Q15714

(UniProtKB/Swiss-Prot/P) Details

TSC22 domain family protein 1

Q969Z0

Interaction Score

0.687

Q86X02

(UniProtKB/Swiss-Prot/P) Details

Cerebellar degeneration-related protein 2-like

Q969Z0

Interaction Score

0.68

P00533

(UniProtKB/Swiss-Prot/P) Details

Epidermal growth factor receptor

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Cell surface (GO:0009986)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Endomembrane system (GO:0012505)	0.972	Experimental: experimental	Organelle	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.972	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.994	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.994	Experimental: experimental	Organelle	PubMed
Nucleus	Nuclear membrane (GO:0031965)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.994	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Early endosome membrane (GO:0031901)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endosome membrane (GO:0010008)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Clathrin coated vesicle membrane (GO:0030665)	0.999	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.86	Unknown: non-traceable author statement	GO	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Membrane raft (GO:0045121)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	AP-2 adaptor complex (GO:0030122)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: pTarget method	LOCATE	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Shc-EGFR complex (GO:0070435)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Receptor complex (GO:0043235)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Apical plasma membrane (GO:0016324)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Basolateral plasma membrane (GO:0016323)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Unknown: HDA	GO	PubMed
Membrane	Synapse (GO:0045202)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed

, PubMed

Q969Z0

Interaction Score

0.68

Q7Z5P4

(UniProtKB/Swiss-Prot/P) Details

17-beta-hydroxysteroid dehydrogenase 13

Q969Z0

Interaction Score

0.68

Q9UBB9

(UniProtKB/Swiss-Prot/P) Details

Tuftelin-interacting protein 11

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.972	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.972	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Spliceosomal complex (GO:0005681)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	U2-type post-mRNA release spliceosomal complex (GO:0071008)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Catalytic step 2 spliceosome (GO:0071013)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear chromosome, telomeric region (GO:0000784)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.86	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q969Z0

Interaction Score

0.679

P40259

(UniProtKB/Swiss-Prot/P) Details

B-cell antigen receptor complex-associated protein beta chain

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	B cell receptor complex (GO:0019815)	0.999	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.971	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.971	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.971	Unknown: unspecified method	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.86	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.86	Unknown: unspecified method	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.8	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Unknown: unspecified method	The Human Protein Atlas	PubMed
Membrane	External side of plasma membrane (GO:0009897)	0.999	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	0.999	Unknown: traceable author statement	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.971	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q969Z0

Interaction Score

0.678

Q7Z3Y8

(UniProtKB/Swiss-Prot/P) Details

Keratin, type I cytoskeletal 27

Q969Z0

Interaction Score

0.672

P49736

(UniProtKB/Swiss-Prot/P) Details

DNA replication licensing factor MCM2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Chromosome (GO:0005694)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nuclear chromosome, telomeric region (GO:0000784)	1	Unknown: HDA	GO	PubMed
Nucleus	MCM complex (GO:0042555)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear origin of replication recognition complex (GO:0005664)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Chromatin (GO:0000785)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q969Z0

Interaction Score

0.671

Q9NYA4

(UniProtKB/Swiss-Prot/P) Details

Myotubularin-related protein 4

Q969Z0

Interaction Score

0.658

Q5JR04

(UniProtKB/TrEmbl/P) Details

Mov10, Moloney leukemia virus 10, homolog (Mouse), isoform CRA_a

Q969Z0

Interaction Score

0.658

Q96FM1

(UniProtKB/Swiss-Prot/P) Details

Post-GPI attachment to proteins factor 3

Q969Z0

Interaction Score

0.628

P04629

(UniProtKB/Swiss-Prot/P) Details

High affinity nerve growth factor receptor

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Neuronal cell body (GO:0043025)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.897	Unknown: unspecified method	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.897	Unknown: unspecified method	The Human Protein Atlas	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.7	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.994	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.994	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	0.994	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Late endosome membrane (GO:0031902)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Early endosome membrane (GO:0031901)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Late endosome (GO:0005770)	0.994	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Lysosome (GO:0005764)	0.897	Predicted: pTarget method	LOCATE	PubMed
Membrane	Dendrite (GO:0030425)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Axon (GO:0030424)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Receptor complex (GO:0043235)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q969Z0

Interaction Score

0.602

Q8WZ55

(UniProtKB/Swiss-Prot/P) Details

Barttin

Q969Z0

Interaction Score

0.56

A0A087WX61

(UniProtKB/TrEmbl/P) Details

CD83 antigen

Q969Z0

Interaction Score

0.56

O15126

(UniProtKB/Swiss-Prot/P) Details

Secretory carrier-associated membrane protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Trans-Golgi network (GO:0005802)	0.994	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Recycling endosome membrane (GO:0055038)	0.994	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Zymogen granule membrane (GO:0042589)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Clathrin-coated vesicle (GO:0030136)	0.994	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Synaptic vesicle membrane (GO:0030672)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.992	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.992	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.992	Predicted: pTarget method	LOCATE	PubMed
Membrane	Cell junction (GO:0030054)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q969Z0

Interaction Score

0.56

Q86VR2

(UniProtKB/Swiss-Prot/P) Details

Reticulophagy regulator 3

Q969Z0

Interaction Score

0.56

Q9UBN6

(UniProtKB/Swiss-Prot/P) Details

Tumor necrosis factor receptor superfamily member 10D

Q969Z0

Interaction Score

0.56

Q01151

(UniProtKB/Swiss-Prot/P) Details

CD83 antigen

Q969Z0

Interaction Score

0.56

J3QKU0

(UniProtKB/TrEmbl/P) Details

Post-GPI attachment to proteins factor 3

Q969Z0

Interaction Score

0.56

Q8WV19

(UniProtKB/Swiss-Prot/P) Details

Vesicle transport protein SFT2A

Q969Z0

Interaction Score

0.56

O95274

(UniProtKB/Swiss-Prot/P) Details

Ly6/PLAUR domain-containing protein 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.971	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.971	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.971	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.971	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.986	Experimental: experimental	eSLDB	PubMed
Membrane	Membrane (GO:0016020)	0.986	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.986	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.986	Unknown: traceable author statement	GO	PubMed
Membrane	Anchored to plasma membrane (GO:0046658)	0.986	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q969Z0

Interaction Score

0.553

Q969P0

(UniProtKB/Swiss-Prot/P) Details

Immunoglobulin superfamily member 8

Q969Z0

Interaction Score

0.49

Q7Z6L0

(UniProtKB/Swiss-Prot/P) Details

Proline-rich transmembrane protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Synaptic vesicle (GO:0008021)	0.79	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Synaptic vesicle membrane (GO:0030672)	0.79	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendritic spine (GO:0043197)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic density (GO:0014069)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Nerve terminal (GO:0043679)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Vesicle (GO:0031982)	0.7	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Presynaptic membrane (GO:0042734)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Postsynaptic membrane (GO:0045211)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q969Z0

Interaction Score

0.49

Q9P0K9

(UniProtKB/Swiss-Prot/P) Details

DOMON domain-containing protein FRRS1L

Q969Z0

Interaction Score

0.357

Q969L2

(UniProtKB/Swiss-Prot/P) Details

Protein MAL2

Q969Z0

Interaction Score

0.299

P0C7P0

(UniProtKB/Swiss-Prot/P) Details

CDGSH iron-sulfur domain-containing protein 3, mitochondrial

Q969Z0

Interaction Score

0.21

P21246

(UniProtKB/Swiss-Prot/P) Details

Pleiotrophin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.998	Experimental: experimental	eSLDB	PubMed
Membrane	Cell surface (GO:0009986)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.8	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.998	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.998	Experimental: experimental	Human Proteinpedia	PubMed
Extracellular	Extracellular region (GO:0005576)	0.998	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.998	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.998	Experimental: experimental	MatrixDB	PubMed
Extracellular	Basement membrane (GO:0005604)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Membrane (GO:0016020)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Membrane (GO:0016020)	0.931	Experimental: experimental	MatrixDB	PubMed
Membrane	Neuromuscular junction (GO:0031594)	0.931	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

Q969Z0

Interaction Score

0.21

P04201

(UniProtKB/Swiss-Prot/P) Details

Proto-oncogene Mas

Q969Z0

Interaction Score

0.21

P32970

(UniProtKB/Swiss-Prot/P) Details

CD70 antigen

Q969Z0

Interaction Score

E9PFD7

(UniProtKB/TrEmbl/P) Details

Receptor protein-tyrosine kinase

Q969Z0

Interaction Score

E7BSV0

(UniProtKB/TrEmbl/P) Details

Receptor protein-tyrosine kinase

Q969Z0

Interaction Score

F2YGG7

(UniProtKB/TrEmbl/P) Details

Receptor protein-tyrosine kinase

Q969Z0

Interaction Score

Q8IZU0

(UniProtKB/Swiss-Prot/P) Details

Protein FAM9B

Q969Z0

Interaction Score

Q504U8

(UniProtKB/TrEmbl/P) Details

Receptor protein-tyrosine kinase

Q969Z0

Interaction Score

Q9H400

(UniProtKB/Swiss-Prot/P) Details

Lck-interacting transmembrane adapter 1

Q969Z0

Interaction Score

B7Z2I3

(UniProtKB/TrEmbl/P) Details

Receptor protein-tyrosine kinase

Q969Z0

Interaction Score

Q9NUM3

(UniProtKB/Swiss-Prot/P) Details

Zinc transporter ZIP9

Q969Z0

Interaction Score

M0QX28

(UniProtKB/TrEmbl/P) Details

Zinc transporter ZIP9

Q969Z0

Interaction Score

Q6FHY5

(UniProtKB/TrEmbl/P) Details

MEOX2 protein

Q969Z0

Interaction Score

A2RU67

(UniProtKB/Swiss-Prot/P) Details

Protein FAM234B

Q969Z0

Interaction Score

Q9BTV4

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 43

Q969Z0

Interaction Score

Q54A51

(UniProtKB/TrEmbl/P) Details

Basigin (Ok blood group), isoform CRA_a

Q969Z0

Interaction Score

Q9H813

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 206

Q969Z0

Interaction Score

Q04118

(UniProtKB/Swiss-Prot/P) Details

Basic salivary proline-rich protein 3

Q969Z0

Interaction Score

P41587

(UniProtKB/Swiss-Prot/P) Details

Vasoactive intestinal polypeptide receptor 2

Q969Z0

Interaction Score

X5DR71

(UniProtKB/TrEmbl/P) Details

Tyrosine-protein kinase receptor

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Q969Z0

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

Q969Z0

Q8TCS8

Polyribonucleotide nucleotidyltransferase 1, mitochondrial

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q969Z0

P52815

39S ribosomal protein L12, mitochondrial

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q969Z0

O00483

Cytochrome c oxidase subunit NDUFA4

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q969Z0

Q9P032

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q969Z0

Q9UBX3

Mitochondrial dicarboxylate carrier

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q969Z0

Q96I51

RCC1-like G exchanging factor-like protein

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q969Z0

Q9Y6E7

NAD-dependent protein lipoamidase sirtuin-4, mitochondrial

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q969Z0

O75208

Ubiquinone biosynthesis protein COQ9, mitochondrial

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q969Z0

P14854

Cytochrome c oxidase subunit 6B1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q969Z0

Q96MF6

Coenzyme Q-binding protein COQ10 homolog A, mitochondrial

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q969Z0

A1L188

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 8

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q969Z0

Q9C002

Normal mucosa of esophagus-specific gene 1 protein

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q969Z0