Q96DB5

Regulator of microtubule dynamics protein 1 // UniProt Profile

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Species	H. sapiens
Number of Interactions	14 / 19
Average Interaction Score	0.652

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.986	Unknown: inferred from electronic annotation	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Spindle pole (GO:0000922)	0.986	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Centrosome (GO:0005813)	0.986	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Microtubule (GO:0005874)	0.986	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	0.986	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

Q96DB5

Interaction Score

0.993

Q9NTX5

(UniProtKB/Swiss-Prot/P) Details

Ethylmalonyl-CoA decarboxylase

Q96DB5

Interaction Score

0.986

P24941

(UniProtKB/Swiss-Prot/P) Details

Cyclin-dependent kinase 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cyclin-dependent protein kinase holoenzyme complex (GO:0000307)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Cajal body (GO:0015030)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Transcription factor complex (GO:0005667)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Chromosome, telomeric region (GO:0000781)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Condensed chromosome (GO:0000793)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Y chromosome (GO:0000806)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	X chromosome (GO:0000805)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed

Q96DB5

Interaction Score

0.98

P54252

(UniProtKB/Swiss-Prot/P) Details

Ataxin-3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.958	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.958	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.958	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial matrix (GO:0005759)	0.91	Predicted: inferred from sequence or structural similarity	GO	PubMed
Mitochondrion	Mitochondrial membrane (GO:0031966)	0.91	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear inclusion body (GO:0042405)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nuclear matrix (GO:0016363)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.8	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q96DB5

Interaction Score

0.956

P29353

(UniProtKB/Swiss-Prot/P) Details

SHC-transforming protein 1

Q96DB5

Interaction Score

0.947

G3V5T9

(UniProtKB/TrEmbl/P) Details

Cyclin-dependent kinase 2, isoform CRA_c

Q96DB5

Interaction Score

0.947

E7ESI2

(UniProtKB/TrEmbl/P) Details

Cyclin-dependent kinase 2

Q96DB5

Interaction Score

0.945

Q13231

(UniProtKB/Swiss-Prot/P) Details

Chitotriosidase-1

Q96DB5

Interaction Score

0.923

P16104

(UniProtKB/Swiss-Prot/P) Details

Histone H2AX

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Male germ cell nucleus (GO:0001673)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Centrosome (GO:0005813)	0.86	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Chromosome (GO:0005694)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Site of double-strand break (GO:0035861)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Condensed nuclear chromosome (GO:0000794)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nuclear chromatin (GO:0000790)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Replication fork (GO:0005657)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleosome (GO:0000786)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Chromosome, telomeric region (GO:0000781)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	XY body (GO:0001741)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.86	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

Q96DB5

Interaction Score

0.68

Q5TGZ0

(UniProtKB/Swiss-Prot/P) Details

MICOS complex subunit MIC10

Q96DB5

Interaction Score

0.56

A0A087WU07

(UniProtKB/TrEmbl/P) Details

MICOS complex subunit MIC10

Q96DB5

Interaction Score

0.21

P05181

(UniProtKB/Swiss-Prot/P) Details

Cytochrome P450 2E1

Q96DB5

Interaction Score

A0A0A0MS38

(UniProtKB/TrEmbl/P) Details

Ataxin-3

Q96DB5

Interaction Score

C9JQV6

(UniProtKB/TrEmbl/P) Details

Ataxin-3

Q96DB5

Interaction Score

Q9BQB6

(UniProtKB/Swiss-Prot/P) Details

Vitamin K epoxide reductase complex subunit 1

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Q96DB5

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

Q96DB5

Q9NTX5

Ethylmalonyl-CoA decarboxylase

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96DB5

P24941

Cyclin-dependent kinase 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96DB5

P54252

Ataxin-3

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96DB5

P29353

SHC-transforming protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96DB5

G3V5T9

Cyclin-dependent kinase 2, isoform CRA_c

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96DB5

E7ESI2

Cyclin-dependent kinase 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96DB5

Q13231

Chitotriosidase-1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96DB5

P16104

Histone H2AX

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96DB5

Q5TGZ0

MICOS complex subunit MIC10

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96DB5

A0A087WU07

MICOS complex subunit MIC10

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96DB5

P05181

Cytochrome P450 2E1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96DB5

A0A0A0MS38

Ataxin-3

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96DB5