Q96EG1

Arylsulfatase G // UniProt Profile

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Species	H. sapiens
Number of Interactions	31 / 41
Average Interaction Score	0.875

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.972	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.972	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum lumen (GO:0005788)	0.972	Unknown: traceable author statement	GO	PubMed
Cytosol	Lysosome (GO:0005764)	0.94	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Lysosome (GO:0005764)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.8	Experimental: inferred from direct assay	GO	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	MatrixDB	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

Q96EG1

Interaction Score

Q9Y6A9

(UniProtKB/Swiss-Prot/P) Details

Signal peptidase complex subunit 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endomembrane system (GO:0012505)	0.972	Experimental: experimental	Organelle	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.972	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Signal peptidase complex (GO:0005787)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Integral to endoplasmic reticulum membrane (GO:0030176)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Integral to endoplasmic reticulum membrane (GO:0030176)	1	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.94	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.94	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Organelle membrane (GO:0031090)	0.972	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q96EG1

Interaction Score

Q6NUQ4

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 214

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytoplasmic microtubule (GO:0005881)	0.992	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.79	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q96EG1

Interaction Score

0.999

P27824

(UniProtKB/Swiss-Prot/P) Details

Calnexin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Myelin sheath (GO:0043209)	0.966	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Neuronal cell body (GO:0043025)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Ribosome (GO:0005840)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Rough endoplasmic reticulum (GO:0005791)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Smooth endoplasmic reticulum (GO:0005790)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum lumen (GO:0005788)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Integral to lumenal side of endoplasmic reticulum membrane (GO:0071556)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum quality control compartment (GO:0044322)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Melanosome (GO:0042470)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendrite cytoplasm (GO:0032839)	0.966	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendritic spine (GO:0043197)	0.966	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Axon (GO:0030424)	0.966	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.96	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.96	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.966	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.966	Experimental: experimental	eSLDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.657	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q96EG1

Interaction Score

0.999

Q9Y5Z0

(UniProtKB/Swiss-Prot/P) Details

Beta-secretase 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.971	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Cell surface (GO:0009986)	0.971	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.971	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.971	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.971	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Lysosome (GO:0005764)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.971	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.971	Unknown: non-traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.971	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q96EG1

Interaction Score

0.999

Q15262

(UniProtKB/Swiss-Prot/P) Details

Receptor-type tyrosine-protein phosphatase kappa

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Cell surface (GO:0009986)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Neuronal cell body (GO:0043025)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.972	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.972	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Dendrite (GO:0030425)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Axon (GO:0030424)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Photoreceptor outer segment (GO:0001750)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Unknown: non-traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Leading edge membrane (GO:0031256)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Unknown: non-traceable author statement	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Adherens junction (GO:0005912)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Cell-cell junction (GO:0005911)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q96EG1

Interaction Score

0.998

Q9NZJ5

(UniProtKB/Swiss-Prot/P) Details

Eukaryotic translation initiation factor 2-alpha kinase 3

Q96EG1

Interaction Score

0.997

P14735

(UniProtKB/Swiss-Prot/P) Details

Insulin-degrading enzyme

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	0.972	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosolic proteasome complex (GO:0031597)	1	Unknown: inferred from electronic annotation	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.94	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Peroxisome (GO:0005777)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Peroxisomal matrix (GO:0005782)	1	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.96	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Membrane (GO:0016020)	0.972	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.972	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q96EG1

Interaction Score

0.995

Q9H497

(UniProtKB/Swiss-Prot/P) Details

Torsin-3A

Q96EG1

Interaction Score

0.987

Q14696

(UniProtKB/Swiss-Prot/P) Details

LRP chaperone MESD

Q96EG1

Interaction Score

0.987

Q96PC5

(UniProtKB/Swiss-Prot/P) Details

Melanoma inhibitory activity protein 2

Q96EG1

Interaction Score

0.984

P68366

(UniProtKB/Swiss-Prot/P) Details

Tubulin alpha-4A chain

Q96EG1

Interaction Score

0.981

O15320

(UniProtKB/Swiss-Prot/P) Details

Endoplasmic reticulum export factor CTAGE5

Q96EG1

Interaction Score

0.98

X6R2S6

(UniProtKB/TrEmbl/P) Details

Signal peptidase complex subunit 1 homolog

Q96EG1

Interaction Score

0.977

Q5TG12

(UniProtKB/TrEmbl/P) Details

Receptor-type tyrosine-protein phosphatase kappa

Q96EG1

Interaction Score

0.975

Q7Z4W2

(UniProtKB/Swiss-Prot/P) Details

Lysozyme-like protein 2

Q96EG1

Interaction Score

0.97

Q99675

(UniProtKB/Swiss-Prot/P) Details

Cell growth regulator with RING finger domain protein 1

Q96EG1

Interaction Score

0.968

Q8NBK3

(UniProtKB/Swiss-Prot/P) Details

Formylglycine-generating enzyme

Q96EG1

Interaction Score

0.95

P49840

(UniProtKB/Swiss-Prot/P) Details

Glycogen synthase kinase-3 alpha

Q96EG1

Interaction Score

0.94

Q9BZG8

(UniProtKB/Swiss-Prot/P) Details

2-(3-amino-3-carboxypropyl)histidine synthase subunit 1

Q96EG1

Interaction Score

0.939

Q9H0R6

(UniProtKB/Swiss-Prot/P) Details

Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial

Q96EG1

Interaction Score

0.939

P78362

(UniProtKB/Swiss-Prot/P) Details

SRSF protein kinase 2

Q96EG1

Interaction Score

0.938

O94952

(UniProtKB/Swiss-Prot/P) Details

F-box only protein 21

Q96EG1

Interaction Score

0.934

Q3ZCM7

(UniProtKB/Swiss-Prot/P) Details

Tubulin beta-8 chain

Q96EG1

Interaction Score

0.855

Q8IUQ5

(UniProtKB/TrEmbl/P) Details

F-box protein 21, isoform CRA_b

Q96EG1

Interaction Score

0.806

Q59EZ1

(UniProtKB/TrEmbl/P) Details

Protein tyrosine phosphatase, receptor type, K variant

Q96EG1

Interaction Score

0.68

Q68DI6

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein DKFZp781H1925

Q96EG1

Interaction Score

0.658

Q4G104

(UniProtKB/TrEmbl/P) Details

F-box only protein 21

Q96EG1

Interaction Score

0.56

Q59FD2

(UniProtKB/TrEmbl/P) Details

CTAGE family, member 5 isoform 1 variant

Q96EG1

Interaction Score

0.56

Q86WJ2

(UniProtKB/TrEmbl/P) Details

Mutant receptor type protein tyrosine phosphatase K

Q96EG1

Interaction Score

0.56

Q4G155

(UniProtKB/TrEmbl/P) Details

CTAGE5 protein

Q96EG1

Interaction Score

A8MPS7

(UniProtKB/Swiss-Prot/P) Details

Carbohydrate deacetylase

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Q96EG1

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

Q96EG1

Q9Y6A9

Signal peptidase complex subunit 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96EG1

Q6NUQ4

Transmembrane protein 214

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96EG1

P27824

Calnexin

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96EG1

Q9Y5Z0

Beta-secretase 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96EG1

Q15262

Receptor-type tyrosine-protein phosphatase kappa

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96EG1

Q9NZJ5

Eukaryotic translation initiation factor 2-alpha kinase 3

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96EG1

P14735

Insulin-degrading enzyme

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96EG1

Q9H497

Torsin-3A

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96EG1

Q14696

LRP chaperone MESD

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96EG1

Q96PC5

Melanoma inhibitory activity protein 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96EG1

P68366

Tubulin alpha-4A chain

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96EG1

O15320

Endoplasmic reticulum export factor CTAGE5

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96EG1