Q96FV0

Leucine-rich repeat-containing protein 46 // UniProt Profile

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Species	H. sapiens
Number of Interactions	27 / 32
Average Interaction Score	0.728

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

Q96FV0

Interaction Score

0.982

P22059

(UniProtKB/Swiss-Prot/P) Details

Oxysterol-binding protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleolus (GO:0005730)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Trans-Golgi network (GO:0005802)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.992	Experimental: experimental	eSLDB	PubMed
Membrane	Membrane (GO:0016020)	0.992	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.992	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q96FV0

Interaction Score

0.975

Q9Y2I8

(UniProtKB/Swiss-Prot/P) Details

WD repeat-containing protein 37

Q96FV0

Interaction Score

0.973

P29597

(UniProtKB/Swiss-Prot/P) Details

Non-receptor tyrosine-protein kinase TYK2

Q96FV0

Interaction Score

0.971

P56282

(UniProtKB/Swiss-Prot/P) Details

DNA polymerase epsilon subunit 2

Q96FV0

Interaction Score

0.971

Q8NCD3

(UniProtKB/Swiss-Prot/P) Details

Holliday junction recognition protein

Q96FV0

Interaction Score

0.969

Q6UWE0

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase LRSAM1

Q96FV0

Interaction Score

0.962

Q86W34

(UniProtKB/Swiss-Prot/P) Details

Archaemetzincin-2

Q96FV0

Interaction Score

0.957

P0C1Z6

(UniProtKB/Swiss-Prot/P) Details

TCF3 fusion partner

Q96FV0

Interaction Score

0.956

Q9UIU6

(UniProtKB/Swiss-Prot/P) Details

Homeobox protein SIX4

Q96FV0

Interaction Score

0.951

Q8WUD4

(UniProtKB/Swiss-Prot/P) Details

Coiled-coil domain-containing protein 12

Q96FV0

Interaction Score

0.949

Q9NVA1

(UniProtKB/Swiss-Prot/P) Details

Ubiquinol-cytochrome-c reductase complex assembly factor 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.988	Experimental: experimental	Human Proteinpedia	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.988	Predicted: pTarget method	LOCATE	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	0.988	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.79	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q96FV0

Interaction Score

0.928

Q8N3E9

(UniProtKB/Swiss-Prot/P) Details

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

Q96FV0

Interaction Score

0.923

Q9UM11

(UniProtKB/Swiss-Prot/P) Details

Fizzy-related protein homolog

Q96FV0

Interaction Score

0.897

Q07864

(UniProtKB/Swiss-Prot/P) Details

DNA polymerase epsilon catalytic subunit A

Q96FV0

Interaction Score

0.85

J3KR35

(UniProtKB/TrEmbl/P) Details

Coiled-coil domain containing 12, isoform CRA_a

Q96FV0

Interaction Score

0.785

P20226

(UniProtKB/Swiss-Prot/P) Details

TATA-box-binding protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
N/A	Transcriptional preinitiation complex (GO:0097550)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Female pronucleus (GO:0001939)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Male pronucleus (GO:0001940)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Transcription factor TFIIA complex (GO:0005672)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Transcription factor TFIID complex (GO:0005669)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Nucleus	Nuclear chromatin (GO:0000790)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear euchromatin (GO:0005719)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q96FV0

Interaction Score

0.785

Q99697

(UniProtKB/Swiss-Prot/P) Details

Pituitary homeobox 2

Q96FV0

Interaction Score

0.783

Q9Y3A4

(UniProtKB/Swiss-Prot/P) Details

Ribosomal RNA-processing protein 7 homolog A

Q96FV0

Interaction Score

0.7

Q8NBZ0

(UniProtKB/Swiss-Prot/P) Details

INO80 complex subunit E

Q96FV0

Interaction Score

0.692

J3KNE2

(UniProtKB/TrEmbl/P) Details

INO80 complex subunit E

Q96FV0

Interaction Score

0.658

Q32MN7

(UniProtKB/TrEmbl/P) Details

TATA box binding protein, isoform CRA_a

Q96FV0

Interaction Score

0.56

P55084

(UniProtKB/Swiss-Prot/P) Details

Trifunctional enzyme subunit beta, mitochondrial

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial nucleoid (GO:0042645)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial envelope (GO:0005740)	1	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial outer membrane (GO:0005741)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.8	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q96FV0

Interaction Score

0.49

Q86VP3

(UniProtKB/Swiss-Prot/P) Details

Phosphofurin acidic cluster sorting protein 2

Q96FV0

Interaction Score

Q3KRB6

(UniProtKB/TrEmbl/P) Details

Chromosome 20 open reading frame 44, isoform CRA_g

Q96FV0

Interaction Score

A0A024R7E4

(UniProtKB/TrEmbl/P) Details

Tyrosine-protein kinase

Q96FV0

Interaction Score

F5GZQ3

(UniProtKB/TrEmbl/P) Details

Trifunctional enzyme subunit beta, mitochondrial

Q96FV0

Interaction Score

Q9NX36

(UniProtKB/Swiss-Prot/P) Details

DnaJ homolog subfamily C member 28

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Q96FV0

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

Q96FV0

P22059

Oxysterol-binding protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96FV0

Q9Y2I8

WD repeat-containing protein 37

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96FV0

P29597

Non-receptor tyrosine-protein kinase TYK2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96FV0

P56282

DNA polymerase epsilon subunit 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96FV0

Q8NCD3

Holliday junction recognition protein

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96FV0

Q6UWE0

E3 ubiquitin-protein ligase LRSAM1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96FV0

Q86W34

Archaemetzincin-2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96FV0

P0C1Z6

TCF3 fusion partner

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96FV0

Q9UIU6

Homeobox protein SIX4

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96FV0

Q8WUD4

Coiled-coil domain-containing protein 12

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96FV0

Q9NVA1

Ubiquinol-cytochrome-c reductase complex assembly factor 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96FV0

Q8N3E9

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96FV0