Q96FV2

Secernin-2 // UniProt Profile

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Species	H. sapiens
Number of Interactions	24 / 28
Average Interaction Score	0.843

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.937	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.937	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.937	Unknown: HDA	GO	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

Q96FV2

Interaction Score

0.989

Q5QP82

(UniProtKB/Swiss-Prot/P) Details

DDB1- and CUL4-associated factor 10

Q96FV2

Interaction Score

0.986

P25963

(UniProtKB/Swiss-Prot/P) Details

NF-kappa-B inhibitor alpha

Q96FV2

Interaction Score

0.984

P49006

(UniProtKB/Swiss-Prot/P) Details

MARCKS-related protein

Q96FV2

Interaction Score

0.983

Q8IZH2

(UniProtKB/Swiss-Prot/P) Details

5'-3' exoribonuclease 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Neuronal cell body (GO:0043025)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.996	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasmic mRNA processing body (GO:0000932)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.996	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.937	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.937	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.937	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Dendrite (GO:0030425)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.997	Experimental: experimental	eSLDB	PubMed
Membrane	Membrane (GO:0016020)	0.997	Unknown: HDA	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.997	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.997	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Synapse (GO:0045202)	0.997	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q96FV2

Interaction Score

0.983

Q5JSZ5

(UniProtKB/Swiss-Prot/P) Details

Protein PRRC2B

Q96FV2

Interaction Score

0.982

Q13557

(UniProtKB/Swiss-Prot/P) Details

Calcium/calmodulin-dependent protein kinase type II subunit delta

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Sarcoplasmic reticulum membrane (GO:0033017)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.79	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.79	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endocytic vesicle membrane (GO:0030666)	0.3	Unknown: traceable author statement	GO	PubMed
Membrane	Neuron projection (GO:0043005)	0.996	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.996	Unknown: HDA	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.996	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Sarcolemma (GO:0042383)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q96FV2

Interaction Score

0.98

P48431

(UniProtKB/Swiss-Prot/P) Details

Transcription factor SOX-2

Q96FV2

Interaction Score

0.977

O14618

(UniProtKB/Swiss-Prot/P) Details

Copper chaperone for superoxide dismutase

Q96FV2

Interaction Score

0.976

Q9NYB0

(UniProtKB/Swiss-Prot/P) Details

Telomeric repeat-binding factor 2-interacting protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.94	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.94	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nuclear envelope (GO:0005635)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear telomere cap complex (GO:0000783)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Telosome (GO:0070187)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Mre11 complex (GO:0030870)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Chromosome (GO:0005694)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nuclear chromosome (GO:0000228)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nuclear chromosome, telomeric region (GO:0000784)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Chromosome, telomeric region (GO:0000781)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

Q96FV2

Interaction Score

0.963

O15530

(UniProtKB/Swiss-Prot/P) Details

3-phosphoinositide-dependent protein kinase 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Perikaryon (GO:0043204)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Unknown: traceable author statement	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.3	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Cell projection (GO:0042995)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Postsynaptic density (GO:0014069)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q96FV2

Interaction Score

0.961

Q92993

(UniProtKB/Swiss-Prot/P) Details

Histone acetyltransferase KAT5

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.86	Experimental: experimental	eSLDB	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Transcription factor complex (GO:0005667)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Piccolo NuA4 histone acetyltransferase complex (GO:0032777)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	NuA4 histone acetyltransferase complex (GO:0035267)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Swr1 complex (GO:0000812)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q96FV2

Interaction Score

0.956

O75191

(UniProtKB/Swiss-Prot/P) Details

Xylulose kinase

Q96FV2

Interaction Score

0.948

Q9Y597

(UniProtKB/Swiss-Prot/P) Details

BTB/POZ domain-containing protein KCTD3

Q96FV2

Interaction Score

0.935

Q9BU62

(UniProtKB/TrEmbl/P) Details

BAT2L protein

Q96FV2

Interaction Score

0.8

Q9BSI4

(UniProtKB/Swiss-Prot/P) Details

TERF1-interacting nuclear factor 2

Q96FV2

Interaction Score

0.797

Q7Z309

(UniProtKB/Swiss-Prot/P) Details

Protein FAM122B

Q96FV2

Interaction Score

0.752

G1UD79

(UniProtKB/TrEmbl/P) Details

Protein FAM122B

Q96FV2

Interaction Score

0.752

A0A0A0MQT4

(UniProtKB/TrEmbl/P) Details

DDB1- and CUL4-associated factor 10

Q96FV2

Interaction Score

0.75

E9PF82

(UniProtKB/TrEmbl/P) Details

Calcium/calmodulin-dependent protein kinase type II subunit delta

Q96FV2

Interaction Score

0.75

E9PBG7

(UniProtKB/TrEmbl/P) Details

Calcium/calmodulin-dependent protein kinase type II subunit delta

Q96FV2

Interaction Score

0.75

D6R938

(UniProtKB/TrEmbl/P) Details

Calcium/calmodulin-dependent protein kinase (CaM kinase) II delta, isoform CRA_e

Q96FV2

Interaction Score

0.64

Q6FHY5

(UniProtKB/TrEmbl/P) Details

MEOX2 protein

Q96FV2

Interaction Score

0.64

B4DFJ1

(UniProtKB/TrEmbl/P) Details

cDNA FLJ53728, highly similar to TERF1-interacting nuclear factor 2

Q96FV2

Interaction Score

P59536

(UniProtKB/Swiss-Prot/P) Details

Taste receptor type 2 member 41

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Q96FV2

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

Q96FV2

Q5QP82

DDB1- and CUL4-associated factor 10

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96FV2

P25963

NF-kappa-B inhibitor alpha

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96FV2

P49006

MARCKS-related protein

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96FV2

Q8IZH2

5'-3' exoribonuclease 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96FV2

Q5JSZ5

Protein PRRC2B

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96FV2

Q13557

Calcium/calmodulin-dependent protein kinase type II subunit delta

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96FV2

P48431

Transcription factor SOX-2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96FV2

O14618

Copper chaperone for superoxide dismutase

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96FV2

Q9NYB0

Telomeric repeat-binding factor 2-interacting protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96FV2

O15530

3-phosphoinositide-dependent protein kinase 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96FV2

Q92993

Histone acetyltransferase KAT5

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96FV2

O75191

Xylulose kinase

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96FV2