Q99797

Mitochondrial intermediate peptidase // UniProt Profile

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Species	H. sapiens
Number of Interactions	34 / 44
Average Interaction Score	0.6

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial matrix (GO:0005759)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.8	Experimental: experimental	Organelle	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

Q99797

Interaction Score

O00746

(UniProtKB/Swiss-Prot/P) Details

Nucleoside diphosphate kinase, mitochondrial

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular (GO:0005622)	0.7	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial matrix (GO:0005759)	1	Unknown: inferred from electronic annotation	GO	PubMed
Mitochondrion	Mitochondrial intermembrane space (GO:0005758)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	1	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q99797

Interaction Score

0.999

Q9BUB7

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 70, mitochondrial

Q99797

Interaction Score

0.997

Q8IWL3

(UniProtKB/Swiss-Prot/P) Details

Iron-sulfur cluster co-chaperone protein HscB, mitochondrial

Q99797

Interaction Score

0.997

Q6IN84

(UniProtKB/Swiss-Prot/P) Details

rRNA methyltransferase 1, mitochondrial

Q99797

Interaction Score

0.997

Q6YN16

(UniProtKB/Swiss-Prot/P) Details

Hydroxysteroid dehydrogenase-like protein 2

Q99797

Interaction Score

0.991

Q9Y6E7

(UniProtKB/Swiss-Prot/P) Details

NAD-dependent protein lipoamidase sirtuin-4, mitochondrial

Q99797

Interaction Score

0.96

Q9BQP7

(UniProtKB/Swiss-Prot/P) Details

Mitochondrial genome maintenance exonuclease 1

Q99797

Interaction Score

0.958

Q96MF6

(UniProtKB/Swiss-Prot/P) Details

Coenzyme Q-binding protein COQ10 homolog A, mitochondrial

Q99797

Interaction Score

0.94

Q5QPE7

(UniProtKB/TrEmbl/P) Details

Mitochondrial genome maintenance exonuclease 1

Q99797

Interaction Score

0.848

Q9NX40

(UniProtKB/Swiss-Prot/P) Details

OCIA domain-containing protein 1

Q99797

Interaction Score

0.8

P30550

(UniProtKB/Swiss-Prot/P) Details

Gastrin-releasing peptide receptor

Q99797

Interaction Score

0.8

Q13418

(UniProtKB/Swiss-Prot/P) Details

Integrin-linked protein kinase

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Neuronal cell body (GO:0043025)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.972	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.972	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Costamere (GO:0043034)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Sarcomere (GO:0030017)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Stress fiber (GO:0001725)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Lamellipodium (GO:0030027)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendritic shaft (GO:0043198)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	1	Unknown: HDA	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Cell-cell junction (GO:0005911)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Terminal button (GO:0043195)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed

Q99797

Interaction Score

0.8

Q5QPE8

(UniProtKB/TrEmbl/P) Details

Mitochondrial genome maintenance exonuclease 1

Q99797

Interaction Score

0.8

Q96FC7

(UniProtKB/Swiss-Prot/P) Details

Phytanoyl-CoA hydroxylase-interacting protein-like

Q99797

Interaction Score

0.8

A0A087WVT9

(UniProtKB/TrEmbl/P) Details

Nucleoside diphosphate kinase

Q99797

Interaction Score

0.794

Q9NRR8

(UniProtKB/Swiss-Prot/P) Details

CDC42 small effector protein 1

Q99797

Interaction Score

0.79

P42858

(UniProtKB/Swiss-Prot/P) Details

Huntingtin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Inclusion body (GO:0016234)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Late endosome (GO:0005770)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Autophagic vacuole (GO:0005776)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle membrane (GO:0030659)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centriole (GO:0005814)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Dendrite (GO:0030425)	0.988	Experimental: inferred from direct assay	GO	PubMed
Membrane	Axon (GO:0030424)	0.988	Experimental: inferred from direct assay	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.988	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed

Q99797

Interaction Score

0.745

Q14203

(UniProtKB/Swiss-Prot/P) Details

Dynactin subunit 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell leading edge (GO:0031252)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Retromer complex (GO:0030904)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Neuronal cell body (GO:0043025)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cell cortex (GO:0005938)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear envelope (GO:0005635)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intermediate filament cytoskeleton (GO:0045111)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intermediate filament cytoskeleton (GO:0045111)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Spindle (GO:0005819)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Spindle pole (GO:0000922)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule associated complex (GO:0005875)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Cytosol	Dynein complex (GO:0030286)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Dynactin complex (GO:0005869)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Centriole (GO:0005814)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule (GO:0005874)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule plus end (GO:0035371)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Kinetochore (GO:0000776)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Neuron projection (GO:0043005)	0.931	Experimental: inferred from direct assay	GO	PubMed
Membrane	Axon (GO:0030424)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.931	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q99797

Interaction Score

0.722

Q16352

(UniProtKB/Swiss-Prot/P) Details

Alpha-internexin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Myelin sheath (GO:0043209)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nuclear membrane (GO:0031965)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear membrane (GO:0031965)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.999	Experimental: experimental	Organelle	PubMed
Cytosol	Intermediate filament cytoskeleton (GO:0045111)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intermediate filament cytoskeleton (GO:0045111)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Neurofilament (GO:0005883)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular space (GO:0005615)	0.3	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.902	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q99797

Interaction Score

0.688

Q13618

(UniProtKB/Swiss-Prot/P) Details

Cullin-3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cul3-RING ubiquitin ligase complex (GO:0031463)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.937	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.937	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.937	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.86	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Polar microtubule (GO:0005827)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Sperm flagellum (GO:0036126)	0.86	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.86	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q99797

Interaction Score

0.688

Q9BRR6

(UniProtKB/Swiss-Prot/P) Details

ADP-dependent glucokinase

Q99797

Interaction Score

0.64

P20155

(UniProtKB/Swiss-Prot/P) Details

Serine protease inhibitor Kazal-type 2

Q99797

Interaction Score

0.64

Q01524

(UniProtKB/Swiss-Prot/P) Details

Defensin-6

Q99797

Interaction Score

0.468

Q9P286

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein kinase PAK 5

Q99797

Interaction Score

0.3

P0C7P0

(UniProtKB/Swiss-Prot/P) Details

CDGSH iron-sulfur domain-containing protein 3, mitochondrial

Q99797

Interaction Score

0.24

Q16659

(UniProtKB/Swiss-Prot/P) Details

Mitogen-activated protein kinase 6

Q99797

Interaction Score

Q6MZZ3

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein DKFZp686I0746

Q99797

Interaction Score

Q96BQ3

(UniProtKB/Swiss-Prot/P) Details

Tripartite motif-containing protein 43

Q99797

Interaction Score

P01106

(UniProtKB/Swiss-Prot/P) Details

Myc proto-oncogene protein

Q99797

Interaction Score

Q2M3D2

(UniProtKB/Swiss-Prot/P) Details

Exocyst complex component 3-like protein 2

Q99797

Interaction Score

Q8N5D0

(UniProtKB/Swiss-Prot/P) Details

WD and tetratricopeptide repeats protein 1

Q99797

Interaction Score

Q8IWF2

(UniProtKB/Swiss-Prot/P) Details

FAD-dependent oxidoreductase domain-containing protein 2

Q99797

Interaction Score

A0A087WVR4

(UniProtKB/TrEmbl/P) Details

Myc proto-oncogene protein

Q99797

Interaction Score

O43638

(UniProtKB/Swiss-Prot/P) Details

Forkhead box protein S1

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Q99797

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

Q99797

O00746

Nucleoside diphosphate kinase, mitochondrial

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q99797

Q9BUB7

Transmembrane protein 70, mitochondrial

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q99797

Q8IWL3

Iron-sulfur cluster co-chaperone protein HscB, mitochondrial

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q99797

Q6IN84

rRNA methyltransferase 1, mitochondrial

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q99797

Q6YN16

Hydroxysteroid dehydrogenase-like protein 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q99797

Q9Y6E7

NAD-dependent protein lipoamidase sirtuin-4, mitochondrial

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q99797

Q9BQP7

Mitochondrial genome maintenance exonuclease 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q99797

Q96MF6

Coenzyme Q-binding protein COQ10 homolog A, mitochondrial

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q99797

Q5QPE7

Mitochondrial genome maintenance exonuclease 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q99797

Q9NX40

OCIA domain-containing protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q99797

P30550

Gastrin-releasing peptide receptor

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q99797

Q13418

Integrin-linked protein kinase

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q99797