Q9BXR6

Complement factor H-related protein 5 // UniProt Profile

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Species	H. sapiens
Number of Interactions	12 / 14
Average Interaction Score	0.868

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.8	Experimental: inferred from mutant phenotype	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.3	Unknown: non-traceable author statement	GO	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	MatrixDB	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

Q9BXR6

Interaction Score

0.986

Q96BA8

(UniProtKB/Swiss-Prot/P) Details

Cyclic AMP-responsive element-binding protein 3-like protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.995	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.995	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.995	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.86	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Lysosome (GO:0005764)	0.94	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nuclear chromatin (GO:0000790)	0.995	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.972	Experimental: inferred from direct assay	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.972	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q9BXR6

Interaction Score

0.979

Q3SXY8

(UniProtKB/Swiss-Prot/P) Details

ADP-ribosylation factor-like protein 13B

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.979	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.979	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.979	Unknown: unspecified method	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.982	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.982	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	0.982	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	0.979	Unknown: unspecified method	The Human Protein Atlas	PubMed
Cytosol	Axoneme (GO:0005930)	0.979	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Cilium (GO:0005929)	0.937	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Cilium membrane (GO:0060170)	0.937	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Motile cilium (GO:0031514)	0.937	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q9BXR6

Interaction Score

0.973

Q9Y282

(UniProtKB/Swiss-Prot/P) Details

Endoplasmic reticulum-Golgi intermediate compartment protein 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.986	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.986	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum-Golgi intermediate compartment membrane (GO:0033116)	0.986	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.986	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.986	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.853	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.853	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.853	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q9BXR6

Interaction Score

0.952

O43889

(UniProtKB/Swiss-Prot/P) Details

Cyclic AMP-responsive element-binding protein 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.988	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	0.988	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.971	Unknown: inferred by curator	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.971	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	0.971	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.971	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.902	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.902	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.3	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q9BXR6

Interaction Score

0.937

P01024

(UniProtKB/Swiss-Prot/P) Details

Complement C3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.897	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.86	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum lumen (GO:0005788)	0.897	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Secretory granule lumen (GO:0034774)	0.897	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Azurophil granule lumen (GO:0035578)	0.897	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.969	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.969	Predicted: pTarget method	LOCATE	PubMed
Extracellular	Extracellular region (GO:0005576)	0.969	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.969	Unknown: HDA	GO	PubMed
Extracellular	Blood microparticle (GO:0072562)	0.969	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.86	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.86	Unknown: traceable author statement	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.86	Unknown: HDA	GO	PubMed

Interaction Source Database:

HPRD, BioGRID

Interaction Source Publication:

PubMed

Q9BXR6

Interaction Score

0.931

Q5SR56

(UniProtKB/Swiss-Prot/P) Details

Hippocampus abundant transcript-like protein 1

Q9BXR6

Interaction Score

0.929

O00559

(UniProtKB/Swiss-Prot/P) Details

Receptor-binding cancer antigen expressed on SiSo cells

Q9BXR6

Interaction Score

0.901

Q05940

(UniProtKB/Swiss-Prot/P) Details

Synaptic vesicular amine transporter

Q9BXR6

Interaction Score

0.851

P02730

(UniProtKB/Swiss-Prot/P) Details

Band 3 anion transport protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Z disc (GO:0030018)	0.958	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cortical cytoskeleton (GO:0030863)	0.958	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Experimental: experimental	MatrixDB	PubMed
Extracellular	Blood microparticle (GO:0072562)	0.86	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Unknown: non-traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Basolateral plasma membrane (GO:0016323)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.958	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q9BXR6

Interaction Score

0.848

P02545

(UniProtKB/Swiss-Prot/P) Details

Prelamin-A/C

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endomembrane system (GO:0012505)	0.998	Experimental: experimental	Organelle	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Unknown: HDA	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Lamin filament (GO:0005638)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nuclear membrane (GO:0031965)	1	Unknown: HDA	GO	PubMed
Nucleus	Nuclear envelope (GO:0005635)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.998	Experimental: experimental	Organelle	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.8	Experimental: experimental	MatrixDB	PubMed
Cytosol	Organelle inner membrane (GO:0019866)	0.998	Experimental: experimental	Organelle	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9BXR6

Interaction Score

0.569

Q8TED1

(UniProtKB/Swiss-Prot/P) Details

Probable glutathione peroxidase 8

Q9BXR6

Interaction Score

0.56

Q5TCI8

(UniProtKB/TrEmbl/P) Details

Prelamin-A/C

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Q9BXR6

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

Q9BXR6

Q96BA8

Cyclic AMP-responsive element-binding protein 3-like protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9BXR6

Q3SXY8

ADP-ribosylation factor-like protein 13B

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9BXR6

Q9Y282

Endoplasmic reticulum-Golgi intermediate compartment protein 3

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9BXR6

O43889

Cyclic AMP-responsive element-binding protein 3

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9BXR6

P01024

Complement C3

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9BXR6

Q5SR56

Hippocampus abundant transcript-like protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9BXR6

O00559

Receptor-binding cancer antigen expressed on SiSo cells

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9BXR6

Q05940

Synaptic vesicular amine transporter

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9BXR6

P02730

Band 3 anion transport protein

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9BXR6

P02545

Prelamin-A/C

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9BXR6

Q8TED1

Probable glutathione peroxidase 8

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9BXR6

Q5TCI8

Prelamin-A/C

Localizations:

Interaction Source Database:

Interaction Source Publication: