Q9HCN3

Post-GPI attachment to proteins factor 6    //   UniProt Profile 

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Species

H. sapiens

Number of Interactions

16 / 16

Average Interaction Score

0.868

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Lysosomal membrane (GO:0005765) 0.51 Unknown: HDA GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.988 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.988 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Intercellular bridge (GO:0045171) 0.988 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Integral to membrane (GO:0016021) 0.987 Predicted: SVM decision tree eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.987 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.987 Experimental: experimental Organelle PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.987 Unknown: non-traceable author statement GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.51 Unknown: HDA GO PubMed 

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

Q9HCN3

Interaction Score
1

Q8TCT7

(UniProtKB/Swiss-Prot/P) Details

Signal peptide peptidase-like 2B

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleoplasm (GO:0005654) 0.96 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Integral to cytosolic side of endoplasmic reticulum membrane (GO:0071458) 0.999 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Integral to lumenal side of endoplasmic reticulum membrane (GO:0071556) 0.999 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi membrane (GO:0000139) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Golgi-associated vesicle membrane (GO:0030660) 0.999 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endosome membrane (GO:0010008) 0.999 Experimental: inferred from direct assay GO PubMed 
Cytosol Lysosomal membrane (GO:0005765) 0.998 Experimental: inferred from direct assay GO PubMed 
Cytosol Centrosome (GO:0005813) 0.998 Experimental: inferred from direct assay GO PubMed 
Cytosol Centrosome (GO:0005813) 0.998 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Actin cytoskeleton (GO:0015629) 0.998 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.998 Experimental: inferred from direct assay GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.998 Predicted: SVM decision tree eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.998 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.998 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9HCN3

Interaction Score
0.999

Q9UN42

(UniProtKB/Swiss-Prot/P) Details

Protein ATP1B4

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nuclear inner membrane (GO:0005637) 0.86 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear envelope (GO:0005635) 0.86 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.991 Predicted: SVM decision tree eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.991 Predicted: pTarget method LOCATE PubMed 
Membrane Plasma membrane (GO:0005886) 0.991 Experimental: experimental Organelle PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.991 Unknown: traceable author statement GO PubMed 
Membrane Sodium:potassium-exchanging ATPase complex (GO:0005890) 0.991 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9HCN3

Interaction Score
0.998

P61978

(UniProtKB/Swiss-Prot/P) Details

Heterogeneous nuclear ribonucleoprotein K

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.996 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.996 Unknown: traceable author statement GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.996 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasmic stress granule (GO:0010494) 0.996 Predicted: inferred from sequence or structural similarity GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Catalytic step 2 spliceosome (GO:0071013) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Podosome (GO:0002102) 0.996 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nuclear chromatin (GO:0000790) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Cell projection (GO:0042995) 0.657 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.96 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular matrix (GO:0031012) 0.96 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.657 Unknown: HDA GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.996 Unknown: HDA GO PubMed 
Membrane Focal adhesion (GO:0005925) 0.657 Unknown: HDA GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q9HCN3

Interaction Score
0.997

Q96FT7

(UniProtKB/Swiss-Prot/P) Details

Acid-sensing ion channel 4

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.996 Predicted: SVM decision tree eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.996 Predicted: pTarget method LOCATE PubMed 
Membrane Plasma membrane (GO:0005886) 0.996 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 0.996 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.996 Unknown: traceable author statement GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9HCN3

Interaction Score
0.995

Q96GX1

(UniProtKB/Swiss-Prot/P) Details

Tectonic-2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.902 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.902 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Cytoskeleton (GO:0005856) 0.902 Unknown: inferred from electronic annotation GO PubMed 
Membrane TCTN-B9D complex (GO:0036038) 0.971 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Cilium membrane (GO:0060170) 0.971 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.971 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.971 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9HCN3

Interaction Score
0.991

Q86T26

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protease serine 11B

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Plasma membrane (GO:0005886) 0.86 Experimental: inferred from direct assay GO PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.3 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9HCN3

Interaction Score
0.977

Q15323

(UniProtKB/Swiss-Prot/P) Details

Keratin, type I cuticular Ha1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.999 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.999 Unknown: traceable author statement GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 0.999 Experimental: experimental Organelle PubMed 
Cytosol Intermediate filament (GO:0005882) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.79 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular space (GO:0005615) 0.79 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.999 Unknown: HDA GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q9HCN3

Interaction Score
0.961

Q7Z3S9

(UniProtKB/Swiss-Prot/P) Details

Notch homolog 2 N-terminal-like protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.79 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.79 Predicted: pTarget method LOCATE PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q9HCN3

Interaction Score
0.958

A8MQ03

(UniProtKB/Swiss-Prot/P) Details

Cysteine-rich tail protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Membrane Midbody (GO:0030496) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.86 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nuclear speck (GO:0016607) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.86 Unknown: HDA GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q9HCN3

Interaction Score
0.89

Q04864

(UniProtKB/Swiss-Prot/P) Details

Proto-oncogene c-Rel

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.91 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol I-kappaB/NF-kappaB complex (GO:0033256) 0.91 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Nucleus (GO:0005634) 0.994 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.994 Experimental: inferred from mutant phenotype GO PubMed 
Nucleus Nucleus (GO:0005634) 0.994 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.994 Unknown: traceable author statement GO PubMed 
Nucleus Transcription factor complex (GO:0005667) 0.994 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

Q9HCN3

Interaction Score
0.772

P60328

(UniProtKB/Swiss-Prot/P) Details

Keratin-associated protein 12-3

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.51 Unknown: traceable author statement GO PubMed 
Cytosol Keratin filament (GO:0045095) 0.51 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.7 Predicted: pTarget method LOCATE PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q9HCN3

Interaction Score
0.772

P60409

(UniProtKB/Swiss-Prot/P) Details

Keratin-associated protein 10-7

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.51 Unknown: traceable author statement GO PubMed 
Cytosol Keratin filament (GO:0045095) 0.51 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.7 Predicted: pTarget method LOCATE PubMed 

Interaction Source Database:

CCSB, IntAct, BioGRID

Interaction Source Publication:

PubMed 

Q9HCN3

Interaction Score
0.772

Q07627

(UniProtKB/Swiss-Prot/P) Details

Keratin-associated protein 1-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.51 Unknown: traceable author statement GO PubMed 
Cytosol Keratin filament (GO:0045095) 0.51 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.7 Predicted: pTarget method LOCATE PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q9HCN3

Interaction Score
0.772

P60410

(UniProtKB/Swiss-Prot/P) Details

Keratin-associated protein 10-8

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.51 Unknown: traceable author statement GO PubMed 
Cytosol Keratin filament (GO:0045095) 0.51 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.7 Predicted: pTarget method LOCATE PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q9HCN3

Interaction Score
0.772

P26371

(UniProtKB/Swiss-Prot/P) Details

Keratin-associated protein 5-9

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.51 Unknown: traceable author statement GO PubMed 
Cytosol Keratin filament (GO:0045095) 0.51 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.7 Predicted: pTarget method LOCATE PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q9HCN3

Interaction Score
0.26

P60369

(UniProtKB/Swiss-Prot/P) Details

Keratin-associated protein 10-3

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.51 Unknown: traceable author statement GO PubMed 
Cytosol Keratin filament (GO:0045095) 0.51 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

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ComPPI is published in Nucleic Acids Research Database Issue 2015