Q9NRS6

Sorting nexin-15 // UniProt Profile

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Species	H. sapiens
Number of Interactions	16 / 21
Average Interaction Score	0.934

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.996	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleolus (GO:0005730)	0.988	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Cytoplasmic vesicle membrane (GO:0030659)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: non-traceable author statement	GO	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

Q9NRS6

Interaction Score

Q86VN1

(UniProtKB/Swiss-Prot/P) Details

Vacuolar protein-sorting-associated protein 36

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.86	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.998	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Late endosome membrane (GO:0031902)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	ESCRT II complex (GO:0000814)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Lysosome (GO:0005764)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Lysosome (GO:0005764)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9NRS6

Interaction Score

Q9NQC3

(UniProtKB/Swiss-Prot/P) Details

Reticulon-4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endomembrane system (GO:0012505)	0.972	Experimental: experimental	Organelle	PubMed
Cytosol	Neuronal cell body (GO:0043025)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Intracellular (GO:0005622)	0.972	Experimental: inferred from mutant phenotype	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Experimental: experimental	Organelle	PubMed
Nucleus	Nuclear envelope (GO:0005635)	0.988	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum tubular network (GO:0071782)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Integral to endoplasmic reticulum membrane (GO:0030176)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Integral to endoplasmic reticulum membrane (GO:0030176)	1	Experimental: experimental	Organelle	PubMed
Membrane	Dendritic growth cone (GO:0044294)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic density (GO:0014069)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.897	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.897	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed

, PubMed

Q9NRS6

Interaction Score

Q9UI14

(UniProtKB/Swiss-Prot/P) Details

Prenylated Rab acceptor protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.96	Experimental: experimental	eSLDB	PubMed
Nucleus	Fibrillar center (GO:0001650)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear membrane (GO:0031965)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.971	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.971	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.971	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Synaptic vesicle (GO:0008021)	0.971	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.952	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.952	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.952	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.952	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Vesicle (GO:0031982)	0.96	Experimental: experimental	eSLDB	PubMed
Membrane	Cell junction (GO:0030054)	0.952	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct, HPRD

Interaction Source Publication:

PubMed

Q9NRS6

Interaction Score

0.998

O60341

(UniProtKB/Swiss-Prot/P) Details

Lysine-specific histone demethylase 1A

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Transcription factor complex (GO:0005667)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear chromosome, telomeric region (GO:0000784)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear chromatin (GO:0000790)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed

Q9NRS6

Interaction Score

0.998

Q9HCE5

(UniProtKB/Swiss-Prot/P) Details

N6-adenosine-methyltransferase non-catalytic subunit

Q9NRS6

Interaction Score

0.992

Q15041

(UniProtKB/Swiss-Prot/P) Details

ADP-ribosylation factor-like protein 6-interacting protein 1

Q9NRS6

Interaction Score

0.988

Q9NYD6

(UniProtKB/Swiss-Prot/P) Details

Homeobox protein Hox-C10

Q9NRS6

Interaction Score

0.978

P02751

(UniProtKB/Swiss-Prot/P) Details

Fibronectin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.971	Predicted: SVM decision tree	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum lumen (GO:0005788)	0.971	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum-Golgi intermediate compartment (GO:0005793)	0.971	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Lysosome (GO:0005764)	0.79	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Platelet alpha granule lumen (GO:0031093)	0.971	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	1	Unknown: non-traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	1	Predicted: pTarget method	LOCATE	PubMed
Extracellular	Extracellular region (GO:0005576)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Fibrinogen complex (GO:0005577)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Blood microparticle (GO:0072562)	1	Unknown: HDA	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	1	Experimental: experimental	MatrixDB	PubMed
Extracellular	Basement membrane (GO:0005604)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Membrane (GO:0016020)	0.86	Experimental: experimental	MatrixDB	PubMed
Membrane	Apical plasma membrane (GO:0016324)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.79	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9NRS6

Interaction Score

0.957

R4GMQ1

(UniProtKB/TrEmbl/P) Details

Lysine-specific histone demethylase 1A

Q9NRS6

Interaction Score

0.955

P49902

(UniProtKB/Swiss-Prot/P) Details

Cytosolic purine 5'-nucleotidase

Q9NRS6

Interaction Score

0.942

Q96BY9

(UniProtKB/Swiss-Prot/P) Details

Store-operated calcium entry-associated regulatory factor

Q9NRS6

Interaction Score

0.911

Q96HR9

(UniProtKB/Swiss-Prot/P) Details

Receptor expression-enhancing protein 6

Q9NRS6

Interaction Score

0.895

Q6MZM7

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein DKFZp686O12165

Q9NRS6

Interaction Score

0.895

Q6MZF4

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein DKFZp686F219

Q9NRS6

Interaction Score

0.79

Q53XI4

(UniProtKB/TrEmbl/P) Details

Homeo box C10

Q9NRS6

Interaction Score

0.64

A0A1L5BXV2

(UniProtKB/TrEmbl/P) Details

Receptor expression-enhancing protein

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Q9NRS6

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

Q9NRS6

Q86VN1

Vacuolar protein-sorting-associated protein 36

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9NRS6

Q9NQC3

Reticulon-4

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9NRS6

Q9UI14

Prenylated Rab acceptor protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9NRS6

O60341

Lysine-specific histone demethylase 1A

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9NRS6

Q9HCE5

N6-adenosine-methyltransferase non-catalytic subunit

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9NRS6

Q15041

ADP-ribosylation factor-like protein 6-interacting protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9NRS6

Q9NYD6

Homeobox protein Hox-C10

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9NRS6

P02751

Fibronectin

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9NRS6

R4GMQ1

Lysine-specific histone demethylase 1A

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9NRS6

P49902

Cytosolic purine 5'-nucleotidase

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9NRS6

Q96BY9

Store-operated calcium entry-associated regulatory factor

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9NRS6

Q96HR9

Receptor expression-enhancing protein 6

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9NRS6