Q9NZD4

Alpha-hemoglobin-stabilizing protein    //   UniProt Profile 

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Species

 H. sapiens

Number of Interactions

 16 / 18

Average Interaction Score

 0.766

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.958 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.958 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Hemoglobin complex (GO:0005833) 0.958 Unknown: non-traceable author statement GO PubMed 

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

Q9NZD4

Interaction Score
0.958

P62942

(UniProtKB/Swiss-Prot/P) Details

Peptidyl-prolyl cis-trans isomerase FKBP1A

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Sarcoplasmic reticulum (GO:0016529) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Terminal cisterna (GO:0014802) 0.7 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Z disc (GO:0030018) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Nerve terminal (GO:0043679) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.86 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

CCSB, IntAct, BioGRID

Interaction Source Publication:

PubMed 

Q9NZD4

Interaction Score
0.958

P20618

(UniProtKB/Swiss-Prot/P) Details

Proteasome subunit beta type-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytosol (GO:0005829) 1 Unknown: traceable author statement GO PubMed 
Cytosol Proteasome complex (GO:0000502) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Proteasome core complex (GO:0005839) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Proteasome core complex, beta-subunit complex (GO:0019774) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Nucleus Nucleus (GO:0005634) 0.994 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.994 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.994 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.994 Unknown: traceable author statement GO PubMed 
Secretory-pathway Secretory granule lumen (GO:0034774) 0.3 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.3 Unknown: traceable author statement GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q9NZD4

Interaction Score
0.957

P69905

(UniProtKB/Swiss-Prot/P) Details

Hemoglobin subunit alpha

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Haptoglobin-hemoglobin complex (GO:0031838) 0.996 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytosol (GO:0005829) 0.999 Unknown: traceable author statement GO PubMed 
Cytosol Cytosolic small ribosomal subunit (GO:0022627) 0.999 Experimental: inferred from direct assay GO PubMed 
Cytosol Hemoglobin complex (GO:0005833) 0.999 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endocytic vesicle lumen (GO:0071682) 0.3 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.996 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.996 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular space (GO:0005615) 0.996 Experimental: inferred from direct assay GO PubMed 
Extracellular Blood microparticle (GO:0072562) 0.996 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 0.86 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 0.86 Experimental: experimental MatrixDB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.999 Unknown: HDA GO PubMed 

Interaction Source Database:

HPRD, IntAct, DIP

Interaction Source Publication:

PubMed , PubMed , PubMed 

Q9NZD4

Interaction Score
0.956

Q5D1E8

(UniProtKB/Swiss-Prot/P) Details

Endoribonuclease ZC3H12A

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.998 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.998 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasmic mRNA processing body (GO:0000932) 0.998 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.998 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.998 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.998 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Macromolecular complex (GO:0032991) 0.998 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Rough endoplasmic reticulum (GO:0005791) 0.937 Predicted: inferred from sequence or structural similarity GO PubMed 
Secretory-pathway Rough endoplasmic reticulum membrane (GO:0030867) 0.937 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Extrinsic to endoplasmic reticulum membrane (GO:0042406) 0.937 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 0.998 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID, CCSB, HPRD, IntAct

Interaction Source Publication:

PubMed , PubMed 

Q9NZD4

Interaction Score
0.955

Q05086

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin-protein ligase E3A

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.997 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.997 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.997 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.997 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytosol (GO:0005829) 0.997 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Proteasome complex (GO:0000502) 0.997 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.958 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.958 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.958 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9NZD4

Interaction Score
0.95

Q9HC07

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 165

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.992 Experimental: inferred from direct assay GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.992 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.999 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Trans-Golgi network membrane (GO:0032588) 0.999 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Late endosome membrane (GO:0031902) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Early endosome membrane (GO:0031901) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Endosome membrane (GO:0010008) 0.999 Experimental: inferred from direct assay GO PubMed 
Cytosol Lysosomal membrane (GO:0005765) 0.992 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.86 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.86 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

Q9NZD4

Interaction Score
0.94

P0CAP1

(UniProtKB/Swiss-Prot/P) Details

Myocardial zonula adherens protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.981 Predicted: SVM decision tree eSLDB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol I band (GO:0031674) 0.981 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Z disc (GO:0030018) 0.981 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cortical actin cytoskeleton (GO:0030864) 0.981 Predicted: inferred from biological aspect of ancestor GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Extrinsic to internal side of plasma membrane (GO:0031234) 0.79 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Cell junction (GO:0030054) 0.79 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

Q9NZD4

Interaction Score
0.932

Q9H2G0

(UniProtKB/TrEmbl/P) Details

CTCL tumor antigen se37-2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.973 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.973 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytoplasm (GO:0005737) 0.973 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9NZD4

Interaction Score
0.872

Q8IUQ0

(UniProtKB/Swiss-Prot/P) Details

Clavesin-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Trans-Golgi network (GO:0005802) 0.991 Predicted: inferred from sequence or structural similarity GO PubMed 
Secretory-pathway Trans-Golgi network membrane (GO:0032588) 0.991 Unknown: traceable author statement GO PubMed 
Secretory-pathway Endosome (GO:0005768) 0.991 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Early endosome membrane (GO:0031901) 0.991 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Clathrin-coated vesicle (GO:0030136) 0.991 Predicted: inferred from sequence or structural similarity GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q9NZD4

Interaction Score
0.824

O60216

(UniProtKB/Swiss-Prot/P) Details

Double-strand-break repair protein rad21 homolog

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.86 Experimental: experimental eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.86 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Human Proteinpedia PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nuclear matrix (GO:0016363) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Chromosome (GO:0005694) 1 Unknown: traceable author statement GO PubMed 
Nucleus Nuclear cohesin complex (GO:0000798) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Chromatin (GO:0000785) 1 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Chromosome, centromeric region (GO:0000775) 1 Unknown: traceable author statement GO PubMed 
Nucleus Cohesin complex (GO:0008278) 1 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.3 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9NZD4

Interaction Score
0.766

Q6EEV4

(UniProtKB/Swiss-Prot/P) Details

DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.8 Experimental: experimental Human Proteinpedia PubMed 
Nucleus Nucleus (GO:0005634) 0.996 Experimental: experimental Human Proteinpedia PubMed 
Nucleus Nucleus (GO:0005634) 0.996 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 0.996 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.996 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

HPRD, BioGRID

Interaction Source Publication:

PubMed 

Q9NZD4

Interaction Score
0.766

Q9Y2B5

(UniProtKB/Swiss-Prot/P) Details

VPS9 domain-containing protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.982 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.982 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.982 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q9NZD4

Interaction Score
0.757

P0CAP2

(UniProtKB/Swiss-Prot/P) Details

DNA-directed RNA polymerase II subunit GRINL1A

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Neuronal cell body (GO:0043025) 0.79 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.79 Predicted: SVM decision tree eSLDB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.998 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nuclear envelope (GO:0005635) 0.998 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.998 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus DNA-directed RNA polymerase II, holoenzyme (GO:0016591) 0.998 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed 

Q9NZD4

Interaction Score
0.671

Q0VDC6

(UniProtKB/TrEmbl/P) Details

Peptidylprolyl isomerase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9NZD4

Interaction Score
0

Q9BZD3

(UniProtKB/Swiss-Prot/P) Details

Putative GRINL1B complex locus protein 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
N/A Cellular component (GO:0005575) 0.3 Unknown: no biological data available GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.91 Predicted: SVM decision tree eSLDB PubMed 
Nucleus DNA-directed RNA polymerase II, holoenzyme (GO:0016591) 0.91 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9NZD4

Interaction Score
0

P17024

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein 20

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.958 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.958 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.958 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Plasma membrane (GO:0005886) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

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ComPPI is published in Nucleic Acids Research Database Issue 2015