Q9UPY5

Cystine/glutamate transporter    //   UniProt Profile 

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Species

 H. sapiens

Number of Interactions

 9 / 9

Average Interaction Score

 0.938

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Cell surface (GO:0009986) 0.998 Experimental: inferred from direct assay GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.86 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Rough endoplasmic reticulum (GO:0005791) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.998 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.998 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.998 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.998 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.998 Predicted: inferred from biological aspect of ancestor GO PubMed 

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

Q9UPY5

Interaction Score
1

P16070

(UniProtKB/Swiss-Prot/P) Details

CD44 antigen

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.992 Predicted: SVM decision tree eSLDB PubMed 
Membrane Macrophage migration inhibitory factor receptor complex (GO:0035692) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Cell surface (GO:0009986) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.86 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.992 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.992 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Secretory granule membrane (GO:0030667) 0.992 Unknown: traceable author statement GO PubMed 
Membrane Cell projection (GO:0042995) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Microvillus (GO:0005902) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Lamellipodium membrane (GO:0031258) 1 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Integral to plasma membrane (GO:0005887) 1 Unknown: non-traceable author statement GO PubMed 
Membrane Apical plasma membrane (GO:0016324) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.86 Unknown: HDA GO PubMed 
Membrane Focal adhesion (GO:0005925) 1 Unknown: HDA GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q9UPY5

Interaction Score
1

P08195

(UniProtKB/Swiss-Prot/P) Details

4F2 cell-surface antigen heavy chain

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Cell surface (GO:0009986) 0.997 Unknown: HDA GO PubMed 
Cytosol Cytosol (GO:0005829) 0.972 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.972 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.96 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Melanosome (GO:0042470) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.997 Unknown: HDA GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.997 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.997 Unknown: non-traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.997 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.997 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Apical plasma membrane (GO:0016324) 0.997 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.972 Unknown: HDA GO PubMed 

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed 

Q9UPY5

Interaction Score
0.999

Q86X19

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 17

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Actin cytoskeleton (GO:0015629) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Ciliary transition zone (GO:0035869) 0.994 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane TCTN-B9D complex (GO:0036038) 0.994 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Cilium membrane (GO:0060170) 0.994 Predicted: inferred from sequence or structural similarity GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.994 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.994 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

Q9UPY5

Interaction Score
0.999

Q9BW83

(UniProtKB/Swiss-Prot/P) Details

Intraflagellar transport protein 27 homolog

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.992 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.937 Predicted: PAML algorithm PA-GOSUB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.992 Predicted: inferred from biological aspect of ancestor GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.992 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Endosome (GO:0005768) 0.992 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Centrosome (GO:0005813) 0.937 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Intraflagellar transport particle B (GO:0030992) 0.937 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Cilium (GO:0005929) 0.991 Experimental: inferred from direct assay GO PubMed 
Membrane Motile cilium (GO:0031514) 0.991 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Sperm midpiece (GO:0097225) 0.991 Unknown: inferred from electronic annotation GO PubMed 
Membrane Sperm principal piece (GO:0097228) 0.991 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.991 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q9UPY5

Interaction Score
0.97

O14746

(UniProtKB/Swiss-Prot/P) Details

Telomerase reverse transcriptase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Ribonucleoprotein complex (GO:0030529) 0.999 Experimental: experimental Organelle PubMed 
Cytosol Telomerase holoenzyme complex (GO:0005697) 0.999 Unknown: traceable author statement GO PubMed 
Cytosol Telomerase catalytic core complex (GO:0000333) 0.999 Experimental: inferred from mutant phenotype GO PubMed 
Cytosol Cytosol (GO:0005829) 0.999 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Mitochondrion Mitochondrial nucleoid (GO:0042645) 0.8 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleolus (GO:0005730) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nuclear speck (GO:0016607) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear speck (GO:0016607) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus PML body (GO:0016605) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear telomere cap complex (GO:0000783) 1 Unknown: inferred by curator GO PubMed 
Nucleus RNA-directed RNA polymerase complex (GO:0031379) 1 Predicted: inferred from physical interaction GO PubMed 
Nucleus Chromosome (GO:0005694) 1 Experimental: experimental Organelle PubMed 
Nucleus Nuclear chromosome, telomeric region (GO:0000784) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Chromosome, telomeric region (GO:0000781) 1 Unknown: inferred by curator GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.79 Predicted: SVM decision tree eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.79 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9UPY5

Interaction Score
0.953

Q8N4P2

(UniProtKB/Swiss-Prot/P) Details

Tetratricopeptide repeat protein 30B

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.982 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Centrosome (GO:0005813) 0.982 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Intraflagellar transport particle B (GO:0030992) 0.982 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Cilium (GO:0005929) 0.7 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

Q9UPY5

Interaction Score
0.859

Q14032

(UniProtKB/Swiss-Prot/P) Details

Bile acid-CoA:amino acid N-acyltransferase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.999 Experimental: experimental eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.999 Experimental: inferred from direct assay GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.999 Unknown: unspecified method The Human Protein Atlas PubMed 
Cytosol Peroxisome (GO:0005777) 0.999 Experimental: inferred from direct assay GO PubMed 
Cytosol Peroxisome (GO:0005777) 0.999 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Peroxisomal matrix (GO:0005782) 0.999 Unknown: traceable author statement GO PubMed 

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed 

Q9UPY5

Interaction Score
0.853

Q9UI95

(UniProtKB/Swiss-Prot/P) Details

Mitotic spindle assembly checkpoint protein MAD2B

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.992 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.992 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleolus (GO:0005730) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleolus (GO:0005730) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Unknown: traceable author statement GO PubMed 
Nucleus Zeta DNA polymerase complex (GO:0016035) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Anaphase-promoting complex (GO:0005680) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Spindle (GO:0005819) 0.992 Experimental: inferred from direct assay GO PubMed 
Nucleus Chromosome (GO:0005694) 1 Unknown: inferred by curator GO PubMed 
Nucleus Site of double-strand break (GO:0035861) 1 Unknown: inferred by curator GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q9UPY5

Interaction Score
0.805

Q07627

(UniProtKB/Swiss-Prot/P) Details

Keratin-associated protein 1-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.51 Unknown: traceable author statement GO PubMed 
Cytosol Keratin filament (GO:0045095) 0.51 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.7 Predicted: pTarget method LOCATE PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

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ComPPI is published in Nucleic Acids Research Database Issue 2015